GENERILLO, MA. TRISHAREY C.

SEPTEMBER 13, 2022

BSN II – 02 MA’AM DYNAH ABOGADO

DRUG STUDY

NAME OF THE DOSAGE, ROUTE, INDICATION CONTRAINDICATI SIDE EFFECTS ADVERSE NURSING
DRUG AND FREQUE-NCY ON REACTION CONSIDERATION
(GENERIC/BRAND) OF ADMINIS-
TRATION

Generic Name: Dosage: -Short-term therapy of  Any allergy -Frequent: Phlebitis, CNS: Ototoxicity, -Baseline
Amikacin sulfate 37 mg severe infections to thrombophlebitis. confusion, examinations: C&S,
brought on by aminoglycosi Occasional: Rash, disorientation, renal function, and
Brand Name: Route: susceptible strains of des, kidney fever, urticaria, depression, vestibulocochlear
Amikin /Amikin Intravenous (IV) Pseudomonas or liver pruritus. lethargy, nystagmus, nerve function before
Pediatric species, Escherichia disease, -Rare: Neuromuscular visual disturbances, to the first dose (and

Frequency: coli, Providencia prior hearing blockade (difficulty headache, fever, at regular intervals

Ø24˚(every 24 species, Klebsiella, loss, breathing, drowsiness, numbness, tingling, during therapy;

hours) Enterobacter, and myasthenia weak tremor, closely monitor in the

Serratia species, gravis, paresthesias, older adult, patients
Acinetobacter parkinsonism muscle twitching, with documented ear
species, indole , baby seaizures, muscular problems, renal
positive and indole botulism, and weekness, impairment, or during
negative Proteus lactation are neuromuscular high dose or
species. contraindicati blockade, apnea. prolonged therapy).
-Initial intervention for ons. CV: Palpitations,
staphylococcal  Use with hypotension, -Draw blood 1 hour
infections in scenarios caution in hypertension. after IM or right away
patients who
where penicillin is GI: Nausea, after the end of an IV
are pregnant,
contraindicated, when elderly, or Vomiting, Anorexia, infusion to monitor
who have
infection may be diarrhea, weight peak and trough
hearing loss,
brought on by several kidney loss, stomatitis, amikacin blood levels;
disease,
organisms, or both. increased, draw blood right
dehydration,
-Treatment of severe or salivation, before the next IM or
neuromuscul
infections including splenomegaly. IV dosage to monitor
ar diseases.
bacterial septicemia GU: Nephrotoxicity trough levels.
(including newborn Hematologic:
spesis), infections of Leukemoid reaction, -Periodic serum
the respiratory agranulocytosis, creatinine and BUN
system, bones, joints, granulocytosis, tests, as well as a full
CNS, skin, and soft leukopenia, urinalysis. Weekly
tissues, intra- leukocytosis, audiograms,
abdominal infections, thrombocytopenia, vestibular tests, and
and difficult, recurrent, eosinophilia, daily tests of renal
and postoperative pancytopenia, function are strongly
infections. anemia, hemolytic indicated for patients
anemia, increased receiving therapy for
or decreased more than 10 days.
reticulocyte count, -In the presence of
electrolyte impaired renal
disturbances. function, in newborns,
Hepatic: Hepatic and in older adults,
toxicity; serum creatinine or
hepatomegaly creatinine clearance
Hypersensitivity: (usually preferable)
Purpura, rash, should be monitored
urticara, exfoliative, more frequently. Take
dermatitis, itching. notice that sustained
OTHER: high trough (>8
Superinfections, mg/mL) or peak (>30–
pain and irritation at 35 mg/mL) values are
IM injection sites. linked to toxicity.

-Watch for signs and

symptoms of
ototoxicity which
primarily affects the
cochlear branch; high-
frequency deafness
typically manifests
first and can only be
detected by an
audiometer; indicators
of declining renal
function; respiratory
tract infections and
other symptoms
suggestive of
superinfections; and
 report any
occurrences to a
doctor.

-Keep an eye out for,

and report, auditory
symptoms, such as
tinnitus, roaring
noises, a feeling of
fullness in the ears,
and hearing loss
(dizziness or vertigo,
nystagmus, ataxia).
-Keep an eye on your
I&O, oliguria,
hematuria, and cloudy
urine, and report any
changes.
Nephrotoxicity risk is
decreased by
maintaining patient
hydration; speak with
a doctor
Generic Name: Dosage: -Treatment of - Contraindicated Frequent: Pain at IM Harmful effects on BASELINE
Ampicillin 154 mg illnesses brought on with allergies to injection site, GI the heart EVALUATION:
by salmonella, penicilins, disturbances (mild (hypertension, Ask about any allergy
Brand Name: Route: shigella, or other cephalosporins or diarrhea, nausea, Anaphylaxis, history, particularly.
Ampi, Omnipen, Intravenous (IV) susceptible strains. other allergens. vomiting), oral or ventricular fibrillation Renal impairment;
Penglobe, and gram-positive - Use cautiously with vaginal candidiasis. hardly ever. altered penicillins;
Principen. Frequency: organisms, typhosa, renal disorders. Occasional: hearing/vision, cephalosporins.
Ø12 ˚(every 12 Escherichia coli, Generalized rash, seizures, liver INTERVENTION/
hours) Haemophilus urticaria, phlebitis, damage, and EVALUATION:
influenzae, Proteus thrombophlebitis (with coagulation Report rash (although
mirabilis, Neisseria IV administration), malformations, it is common with
gonorrhoea, headache. Rare: multiple organ ampicillin) or diarrhea
enteroccoci, etc. Dizziness, seizures failure, and sepsis (fever, abdominal
(esp. with IV therapy). may happen. Every pain, mucus, and
-Neisseria possible formulation blood in the stool) as
meningitidis is the is less harmful to the soon as possible.
cause of meningitis. kidneys than may be a sign of
standard colitis brought on by

-After dental, oral, or amphotericin antibiotics). Check for

respiratory operations (Amphocin). phlebitis at the IV site.

in patients at very Check

high risk, prevent Injection location for

bacterial endocarditis. induration and

-Unlabeled use: discomfort.

Cesarean section Observe I&O,

prophylaxis in some urinalysis, and kidney

high-risk patients. function

tests. Be on the
lookout for
 superinfection: fever
vomiting, diarrhea,
vaginal or anal
itchiness, and
changes to the oral
mucosa (ulceration,
ache and erythema).
Patient and family
education:
Maintain antibiotic
therapy for the entire
treatment. Arrange
doses uniformly. More
effective if given two
hours after or one
hour before
food/beverages.IM
injections may cause
discomfort. · Report
any new symptoms,
such as rash or
diarrhea.
Generic Name: Dosage:  Vitamin K  Hypersensiti There may be Rarely will this -To avoid an
Vitamin K 0.1cc deficiency vity to discomfort, medication cause a unintentional dose
prophylaxis vitamin K bruising, or pain very serious allergic doubling, record the
Brand Name: Route:  Hemorrhagic where the injection reaction. However, if administration of the
Phytomenadione, Intramuscular (IM) disease of was made. Rarely, you experience any drug to the newborn.
Phytonadine, newborn there may also be major adverse -Watch for bleeding
Phytonadione, Frequency:  Malabsorption brief episodes of reaction symptoms, (usually occurs on
Vitamin K1 Shortly / 1 hour after syndrome bluish lips, skin, or such as a rash, second or third day).
birth  Cystic nails, temporary itching or swelling Ecchymoses all over
Fibrosis flushing, taste (particularly of the the body or bleeding
 Biliary atresia changes, face, tongue, or from the umbilical

 Hepatic disorientation, throat), severe cord, the site of a

failure rapid heartbeat, dizziness, or circumcision, the

 Antidote to perspiration, or difficulty breathing, nose, or the digestive

warfarin shortness of seek medical tract can all be signs

breath. Inform attention right away. of bleeding.
your doctor or -Keep an eye out for
pharmacist as kernicterus and
soon as possible if jaundice, especially in
any of these side premature babies.
effects persist or -Watch for indications
get worse. of localized
inflammation.
-In order to stop
further bleeding, apply
pressure to the
injection site.
-Defend medication
against light.
give vitamin K before
 performing a
circumcision.
Generic Name: Dosage:  Shields the  Recombinant  Headache.  Pain  For those
Hepatitis B shot 0.5cc child from the hepatitis B  Rash. Pruritus whose

potentially vaccination  Fatigue.  Erythema immune

Brand Name: Route: fatal disease should not  Cold or flu-like  Burning systems have
Engerix B, Heplisav Intramuscular (IM) hepatitis B. be symptoms.  Nodules been
B because administered  Fever  Fatigue weakened,
Frequecy: children with to those who (pyrexia). Headache further doses
24 hours after birth hepatitis B have a could be
 Pins and  Fever
frequently known yeast necessary.
needles  Vertigo
show no allergy, a  A proper cold
(paraesthesia)  Lightheaded
symptoms hypersensitiv chain should
 Dizziness. ness
and may ity to any be maintained
 Pain in the  Flushinig
infect others vaccine for vaccine
joints  Insomnia
without
ingredient, or storage.
showing any (arthralgia).  Irritability
who have  The patient
signs of their  Pain in the  Arthralgia
experienced record needs
infection, muscles  Constipation
a severe to include the
protecting (myalgia).
allergic  Pruritus
batch number
others from  Itching
reaction like  Lupus-like and expiration
the disease. (pruritis).
anaphylaxis syndrome date for the
 Those who  Soreness at
after  Lymphaden injection
may be injection site.
receiving a opathy location
exposed to  Allergic
dose of any  Tachycardia (bronchospas
blood or
reactions such
blood hepatitis B- m).
 containing as lips
products at
work such as vaccine. swelling,

health care tongue and

workers. throat
 Abusers of (angioedema)
injectable or narrowing
drugs. of the airways
 People with a (bronchospas
number of m).
sexual
partners.
 Homosexual
men.
 Haemodialysi
s patients or
those
receiving
certain blood
products.
 People with
chronic liver
disease or
hepatitis C.
 People in
close contact
with a
hepatitis B
 carrier or with
an infected
person.
 Staff and
residents of
homes.
 Inmates and
staff in
prisons.
 Travellers
intending to
stay for long
periods in
areas where
the hepatitis
B incidence is
high.

Generic Name: Dosage:  Prevention of  Hypersensiti  swollen lymph  hives, Assessment &
BCG Vaccine/BGC 0.5cc disseminate, vity. Impaired nodes  difficulty Drug Effects
live severe forms immune  small red breathing,
Route: of response, areas at the  swelling of  Monitor for
Brand Name: Intramuscular (IM) tuberculosis. congenital or site of the face, S&S of
TheraCys® BCG acquired injection. lips, tongue, systemic BCG
TICE® BCG Frequecy: immune (These usually or throat, infection:
24 hours after birth deficiencies appear 10-14  fever, Fever, chills,
(e.g., HIV days after severe
infection, injection and  chills, malaise, or
leukemia, slowly  aches, cough.
lymphoma, decrease in  weakness,  Culture blood
cancer size. They  flu-like and urine, if
treatment, should symptoms, systemic
Hodgkin's disappear  cough, infection is
disease), after about 6 suspected.
 pain or
active months.)  Assess for
burning
tuberculosis,  fever regional
while
acute severe  blood in the lymph node
urinating,
febrile urine enlargement
 a weak
illness,  frequent or and report
stream of
generalized painful fistula
urine,
infected skin urination formation.
 trouble
conditions,  upset stomach Patient & Family
emptying
current or  vomiting Education
the bladder,
previous  Review
 blood in the
evidence of potential
urine,
BCG adverse
 dark-colored
infection, effects.
urine,
urinary tract  Keep
 vomiting,
infection, vaccination
 upper
gross site clean until
stomach
haematuria, local reaction
pain,
14 days of has subsided.
 yellowing of
biopsy, TUR,
or traumatic the skin or  Do not breast
catheterizatio eyes, feed until
n are all  not feeling cleared to do
examples of well, and so by
these  burning, physician.
conditions. itching,
concurrent odor,
treatment discharge,
with pain,
antibiotics, tenderness,
radiation redness, or
therapy, swelling of
bone marrow the genital
inhibitors, or rectal
and area,
immunosupp
ressive drugs