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Introduction

PCOS is the most common hormonal disorder in premenopausal women that influences androgen and estrogen production. It is characterized by irregular periods, infertility, excess hair growth and other metabolic issues like diabetes and heart disease. Current treatments have side effects, so natural treatments with fewer side effects are needed.

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Yahya Kiyani
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42 views1 page

Introduction

PCOS is the most common hormonal disorder in premenopausal women that influences androgen and estrogen production. It is characterized by irregular periods, infertility, excess hair growth and other metabolic issues like diabetes and heart disease. Current treatments have side effects, so natural treatments with fewer side effects are needed.

Uploaded by

Yahya Kiyani
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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PCOS (polycystic ovary syndrome) is the most usual hormonal disorder.

PCOS is the most


frequent ailment among premenopausal and reproductive-age women. PCOS influences
androgen synthesis, estrogen production, and androgen formation in women. [1]Patelanuradha
Jitendra, Thakor Akanksha Pravin, 2012. This disorder is described by symptoms like menstrual
instability, anovulator y infertility, analytic and biochemical hyperandrogenism, along with some
more metabolic demonstration, that results in 30-70 percent females suffering from PCOS [1]
Tosatti, J.A., Alves, M.T., Cândido, A.L., Reis, F.M., Araújo, V.E. and Gomes, K.B, 2020.
According to WHO's estimation, polycystic ovary syndrome has targeted 116 million females all
around the globe in 2012 [5]. Rineesha, K.P. and ST, A, 2021. PCOS is differentiated via at least
two of the following key factors: The presence of hyperandrogenism clinical (hirsutism) and/or
biochemical and either oligo or anovulation and finally presence of polycystic ovarian
morphology[2] Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF,
Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF, 2006.
Metabolic problems linked with PCOS include insulin resistance, dyslipidemia, obesity, Type 2
diabetes, cardiovascular disease, oxidative stress, and hereditary issues. [7-9] Faghfoori Z,
Fazelian S, Shadnoush M, Goodarzi R, 2017. Chatterjee B, Suri J, Suri JC, Mittal P, Adhikari T,
2014. Hyperinsulinemia may also increase abnormal ovarian androgen secretion and develop
abnormal follicles, leading to dysfunctional ovarian and menstrual cycle.[3] Eisenhardt S,
Schwarzmann N, Henschel V, Germeyer A, Von Wolf M, Hamann A, Strowitzki T, 2006.
Women with PCOS are currently treated using a range of methods, including nutritional
modifications and pharmacological treatments. A change in lifestyle is linked to diet, weight
loss, and exercise. Pharmacological therapies include antiandrogens (spironolactone, flutamide),
hypoglycemic medicines (metformin and thiazolidinediones), and estrogen-progestin combos
(oral contraceptives). Though successful, such therapy is costly and can have several side effects,
including increased insulin tolerance, extended menstruation, gastrointestinal problems, and
weight gain [13,14] Jang M, Lee MJ, Lee JM, Bae CS, Kim SH, Ryu JH, 2014. Bates GW,
Legro RS, 2013. As a result, successful treatments based on natural products with fewer side
effects are required. [15] . Ramachandran S, Sanjay AS, Dhanaraju MD, 2013

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