Name: _____________________________________ Date: ______________ Period: ________
DNA Structure Worksheet
In 1953, James Watson and Francis Crick established that the structure of DNA is a double helix. A
double helix is like a twisted ladder. The sides of the ladder are made of alternating sugar and phosphate
molecules. The sugar is deoxyribose. Color all the phosphates brown (one is labeled with a "p"). Color
all the deoxyriboses blue (one is labeled with a "D").
The rungs of the ladder are pairs of 4 types of nitrogen bases. They are called adenine, guanine,
thymine, and cytosine. The bases are known by their coded letters A, G, T, C. These bases always bond in
a certain way. Adenine will only bond to thymine. Guanine will only bond with cytosine.
Color the thymines orange.             Color the adenines green.
Color the guanines purple.             Color the cytosines yellow.
                                      The combination of a single base, a deoxyribose sugar, and a
                                      phosphate make up a nucleotide. The DNA molecule is made of
                                      repeating nucleotides. Color the parts of the nucleotide (make
                                      sure to use the correct colors!). The two sides of the DNA ladder
                                      are held together loosely by hydrogen bonds. The DNA can
                                      "unzip" its hydrogen bonds when it needs to replicate (make a
                                      copy of) itself. The hydrogen bonds are represented by small
                                      circles. Color the hydrogen bonds red.
                                      Answer the following questions.
                                      1. Write out the full name for DNA.
                                      2.  What is a gene?
                                      3.  Where in the cell are chromosomes located?
                                      4.  What two scientists established the structure of DNA?
5.  What is the shape of DNA?
6. What are the sides of the DNA ladder made of?
7.  What are the "rungs" of the DNA ladder made of?
8.  What sugar is found in DNA?
9.  How do the bases bond?
  A bonds with _____  G bonds with _____
10. DNA is made of repeating units called ______________.