INSECTICIDE
CHLORFLUAZURON
Insect growth regulator
Chlorfluazuron is one of the leading benzoylphenylurea IGR insecticides.
This compound, discovered and developed by ISK, was launched in the late
1980’s. Since then, chlorfluazuron has been globally used under the trademark
of Atabron for controlling Lepidopteran pests on cotton, bean, vegetables and
fruit trees, etc.
Chlorfluazuron is an insect growth regulator that inhibits chitin synthesis and
provides good control of various pest insects, especially Lepidoptera, at a low
dose rate.
Chlorfluazuron has very little negative impact on natural enemies and pollinating
insects, and can be used in integrated pest management programs.
Physico-Chemical Properties Toxicology & Ecotoxicology
Chemical structure
Rat LD50 (oral) : > 8,500 mg/kg (m/f)
CI CI F Rat LD50 (dermal) : > 1,000 mg/kg (m/f)
Rat LC50 (inhalation) : > 2.4 mg/L (4 h) (x/f)
F3C O NHCONHCO
Skin irritation : non irritant (rabbit)
N F Eye irritation : irritant but also physical irritant (rabbit)
CI
Skin sensitization : not a sensitizer (guinea pig)
Class : benzoylurea
Avian LD50 (acute oral) : > 2,510 mg/kg (quail)
IUPAC name : 1-[3,5-dichloro-4-(3-chloro-5- Avian LD50 (acute oral) : > 2,510 mg/kg (mallard ducks)
trifluoromethyl-2-pyridyloxy) phenyl]-
3-(2,6-difluorobenzoyl)urea Fish LC50 : > 1,071 mg/L (bluegill, 96 h)
Molecular weight : 540.7 Bees LD50 (oral) : >100 μg/bee
Molecular formula : C20H9Cl3F5N3O3 Daphnia magna EC50 : 0.304 μg/L (48 h)
Vapour pressure : 1.599x10-3 mPa (20°C)
Water solubility : 0.012 mg/L (20°C)
Form : White solid
Development code : IKI-7899
Application Mode of Action
Control of Lepidoptera such as Helicoverpa, Spodoptera and Pseudo- Chlorfluazuron, which acts as an anti-molting agent, inhibits biosynthesis
plusia on soybean; and Plutella, Spodoptera and thrips on vegetables; of chitin in the insect cuticle, which causes loss of cuticle elasticity and
Adoxophyes, Ascotis on tea and fruit trees. Also used on potatoes, firmness, and results in abortive molting.
ornamentals and turf. Application rate : 10-100 g a.i./ha It belongs to IRAC Group 15.
Product
Trade Names ATABRON, ISHIPRON, NICE EAGLE, 愛扶農, 抑太保, etc.
Formulations 5%EC, 10%SC
Registered Countries Asia China, India, Japan, Philippines, South Korea, Taiwan, Thailand, Vietnam, etc.
Americas Argentine, Brazil, Peru, etc.
Crops Corn, Cotton, Fruit trees, Soybean, Tea, Turf, Vegetables, etc.
URL : http://www.iskweb.co.jp E-mail : isk.bio@iskweb.co.jp
ISHIHARA SANGYO KAISHA, LTD.
1-3-15 Edobori, Nishi-ku, Osaka 550-0002 TEL +81-6-6444-7154
INSECTICIDE CHLORFLUAZURON
Insect growth regulator
Inhibition of Larval Molting of Spodoptera Characterisitics
litura by Chlorfluazuron Application
Chitin synthesis inhibitor
Interrupts insect molting and growth
Active against larval stages of a broad spectrum
of Lepidopteran insects
Long residual activity
Active against certain Coleoptera, Hemiptera,
Thysanoptera and Blattodea
Stomach toxin - active through ingestion
Normal Effective at low rates (10-100 g a.i./ha)
Easy to use (liquid formulation)
Abnormal molting when chlorfluazuon was treated at
5th instar larvae Safe to beneficial insects
The Efficacy of Chlorfluazuron on DBM (7 days after application)
Untreated cabbage Chlorfluazuron 5%EC/1 L/ha (50 g a.i./ha)
Pest Spectrum
Lepidoptera Acrolepiopsis nagaimo Adoxophyes honmai Adoxophyes orana
Agrotis ipsilon Alabama argilacea Anticarsia gemmatalis
Archips audax Archips breviplicanus Archips fuscocupreanus
Ascia monuste Ascotis selenaria Autographa nigrisigna
Diaphania indica Helicoverpa armigera Hellula undalis
Homona magnanima Mamestra brassicae Orgyia thyellina
Parapediasia teterrella Pieris rapae Plutella xylostella
Pseudoplusia includens Rachiplusia nu Rhopobota naevana
Spodoptera depravata Spodoptera exigua Spodoptera frugiperda
Spodoptera litura Stathmopoda masinissa Tuta absoluta
Hemiptera Whitefly Bemisia tabacii Trialeurodes vaporariorum
Thysanoptera Thrips Thrips palmi Thrips tabaci Frankliniella occidentalis
Ponticulothrips diospyrosi
Blattodea Termite Coptotermes formosanus Reticulitermes speratus
Coleoptera Anomala octiescostata. Cassida nebulosa Phyllotreta striolata
Popillia japonica Sphenophorus venatus
Helicoverpa armigera Spodoptera litura Plutella xyloatella
URL : http://www.iskweb.co.jp E-mail : isk.bio@iskweb.co.jp
ISHIHARA SANGYO KAISHA, LTD.
1-3-15 Edobori, Nishi-ku, Osaka 550-0002 TEL +81-6-6444-7154
