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MATERIAL SAFETY DATA SHEET

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1. Product and Company Identification
Material name
ENZOL® Enzymatic Detergent
Issue date
9/14/12
Change Order #
1005190
CAS #
Mixture
Revision #
G
MSDS Number
008
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Synonym(s)
CIDEZYME® Enzymatic Detergent
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Manufacturer/Supplier
'Advanced Sterilization Products'
i' 33 Technology Drive, Irvine
CA 92618
Telephone number 1-800-755-5900
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Emergency 24-Hour phone (Access code): 1t760-476-3962 (333623)
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!' 2. Hazards Identification I

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I Physical state Liquid.
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Appearance Clear liquid.
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Emergency overview DANGER

May cause allergic respiratory reaction. Causes skin, eye and respiratory tract irritation.
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OSHA regulatory status This product is hazardous according to OSHA 29 CFR 1910.1200.
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Potential health effects
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Routes of exposure
Inhalation. Ingestion. Skin contabt. Eye contact.

Eyes
Causes eye irritation. ,

Skin
Causes skin irritation. '

Inhalation
May cause respiratory tract irrita~ion.
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May cause allergic respiratory reaction.

Ingestion
Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea.
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Target organs Respiratory system Eye Skin Gastro-intestinal tract
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Chronic effects Not known. I
Signs and symptoms Wheezing. Cough, Shortness ofl breath, Headache, Nausea, Vomiting. Skin irritation. Irritation of
eyes and mucous membranes. Upper respiratory tract irritation.
3. Composition I Information on Ingredients ,I

Com ponents CAS # Percent

Subtilisins I
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9014-01-1 <5
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Com position comments All concentrations are in percent by weight unless ingredient is a gas. GaS concentrations are in
percent by volume. I
4. First Aid Measures I

First aid procedures I

Eye contact Immediately flush eyes with Ple~ty of water for at least 15 minutes. Get medical attention if
irritation develops or persists. I

Skin contact Wash skin thoroughly with soa~ and water. Get medical attention if irritation develops and

persists. I

Inhalation Remove victim to fresh air. If br~athing is difficult, give oxygen. Get medical attention.

Ingestion Immediately rinse mouth and d~ink plenty of water. Keep person under observation. Do not induce

vomiting. If vomiting occurs, keep head low. If person becomes uncomfortable seek medical

advice.

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f,,$'; Notes to physician Treat symptomatically.

ENZOL® Enzymatic Detergent I CPH MSDS NA

MSDS-008 Revision #: G Issue date: 9/14/12 1/5
WARNING: This is a controlled proprietary and confidential document. Verify revision is current p'rior to use.
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 General advice Ensure that medical personnel arei aware of the material(s) involved, and take precautions to
protect themselves.

5. Fire Fighting Measures I

Flammable properties Fire or high temperatures create: I

Extinguishing media I
Suitable extinguishing Extinguish with water spray, carbdn dioxide, dry chemical or material appropriate for the
media surrounding fire. I

Unsuitable extingUishing None.

media

Protection of firefighters

Specific hazards arising None.

from the chemical

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Protective equipment and Self-contained breathing apparatus and full protective clothing must be worn in case of fire.
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precautions for firefighters
Fire fighting Move containers from fire area if you can do it without risk.
equipment/instructions
Specific methods Self-contained breathing apparat4s and full protective clothing must be worn in case of fire.
Hazardous combustion None known. I

products
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6. Accidental Release Measures i

Personal precautions Avoid inhalation and contact with skin and eyes. Use personal protection as recommended in
Section 8 of the MSDS. I
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!' Environmental precautions Avoid discharge into storm drainsl water courses or onto the ground.

:' Methods for containment Stop leak if you can do so without risk.

Methods for cleaning up Use a non-combustible material like vermiculite, sand or earth to soak up the product and place
into a container for later disposal.: Following product recovery, flush area with water.
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Other information Clean up in accordance with all a,pplicable regulations.

7. Handling and Storage I

Handling Provide adequate ventilation. AV~id inhalation of vapors/spray and contact with skin and eyes.
Use appropriate Personal Protective Equipment. Wash thoroughly after handling. Observe good
industrial hygiene practices. I
Storage Store in closed original container,at temperatures at 15 - 30°C (59 - 86°F).
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8. Exposure Controls I Personal Protection
Occupational exposure limits
US. ACGIH Threshold limit Values

Components Type, Value

Subtilisins (9014-01-1) TVVA I 0.0001 mg/m3

Canada. Alberta OEls (Occupational Health & Safety cOde;llschedule 1, Table 2)

Components Type Value
Subtilisins (9014-01-1) Ceiling I 0.0001 mg/m3
Canada. British Columbia OEls. (Occupational Exposure limits for Chemical Substances, Occupational Health and
Safety RegUlation 296/97, as amended) I

Components Type I Value

Subtllisins (9014-01-1) Ceiling 0.0001 mg/rn3
Canada. Ontario OEls. (Ministry of labor· Control of Exposure to Biological or Chemical Agents)
Components Type' Value
Sl.I.btilisins (9014-01-1) Ceiling I 0.0001 rng/m3
Canada. Quebec OElS. (Ministry of Labor· Regulation Respecting the Quality of the Work Environment)
Components Type I Value
Subtilisins (9014-01-1) Ceiling 0.0001 mg/m3
Ii, Mexico. Occupational Exposure Limit Values
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Com ponents Type Value

Subtilisins (9014-01-1) Ceiling 0.0001 mg/m3

ENZOL® Enzymatic Detergent I CPH MSDS NA

MSDS-008 Revision #: G Issue date: 9/14/12 2/5
WARNING: This is a controlled proprietary and confidential document. Verify revision is current prior to use.
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 Exposure guidelines Use personal protective equipment as required. Keep working clothes separately.
Engineering controls Provide adequate ventilation and minimize the risk of inhalation of vapors and mists.
Personal protective equipment
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Eye I face protection Wear safety glasses with side shi~lds.
Skin protection Wear chemical-resistant, impervio~s gloves. Suitable gloves can be recommended by the glove
supplier. Wear suitable protective IClothing.
Respiratory protection In case of risk of inhalation of vapour/aerosols: Use high efficiency particulate respirator with
appropriate filter. I
General hygiene Wash thoroughly after handling. Handle in accordance with good industrial hygiene and safety
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considerations practice. I
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II 9. Physical & Chemical Properties

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Appearance Clear liquid.

Color Violet.

Odor Spearmint.

Odor threshold Not available.

Physical state Liquid.

Form Liquid.

pH 7.8 - 8.8

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I' Melting point Not available.

Freezing point Not available.

Boiling point Not available.

Flash point > 199.4 OF (> 93 DC)

Evaporation rate Not available.

Flammability iimits in air, upper, Not available.

% by volume

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Flammability limits in air, lower, Not available.

( % by volume

Vapor pressure Not available.

Vapor density Not available.

Specific gravity Not available.

Solubility (water) Not available.

Partition coefficient Not available.

(n-octanol/water)

Auto-ignition temperature Not available.

Decomposition temperature Not available.

10. Chemical Stability & Reactivity Information

Chemical stability Stable at normal conditions.

Conditions to avoid Temperatures above 40 DC

Incompatible materials None known.

HazardOUS decomposition Carbon oxides.

products I

Possibility of hazardous Hazardous polymerization does not occur.

reactions !

11. Toxicological Information

Acute effects Ingestion may cause gastrointes~inal irritation, nausea, vomiting and diarrhea.

Local effects Causes skin and eye irritation. May cause irritation of respiratory tract.

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Sensitization May cause allergic respiratory rJaction.

Chronic effects Not known.

Carcinogenicity Not classified.

i: ENZOL® Enzymatic Detergent I CPH MSDS NA

MSDS-008 Revision #: G Issue date: 9/14/12 3/5
WARNING: This is a controlled proprietary and confidentia~ document. Verify revision is current prior to use.
 I
Mutagenicity No data available to indicate prod:uct or any components present at greater than 0.1 % are
mutagenic or genotoxic.
Reproductive effects Not classified. i

Symptoms and target Wheezing. Cough, Shortness of !:breath, Headache, Nausea, Vomiting. Skin irritation. Irritation of
organs eyes and mucous membranes. ujPper respiratory tract irritation.
Further information No other specific acute or chronic health impact noted.

12. Ecological Information

Ecotoxicity Not expected to be harmful to aquatic organisms.
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Environmental effects An environmental hazard cannot be excluded in the event of unprofessional handling or disposal.
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Persistence and No data is available on the degra~ability of this product.
degradability
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Bioaccumulation 1 No data available. I
Accumulation
Partition coefficient Not available.
(n-octanol/water)
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i: Mobility in environmental The product is soluble in water.

!''i media

13. Disposal Considerations

Disposal instructions Dispose of contents/container in ~ccordance with local/regional/national/international regulations.
Waste from residues 1unused Dispose in accordance with all a~plicable regulations.
products I

Contaminated packaging Empty containers should be taker to an approved waste handling site for recycling or disposal.

14. Transport Information

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DOT
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Not regulated as dangerous goods.

lATA

Not regulated as dangerous goods.

IMDG

Not regulated as dangerous goods.

TOG
Not regulated as dangerous goods.

15. Regulatory Information

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US federal regulations This product is hazardous accord:ing to OSHA 29 CFR 1910.1200.

All components are on the U.S. E;PA TSCA Inventory List.
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TSCA Section 12(b) Export Notification(40 CFR 707, Subpt. D)
Not regulated.
CERCLA (Superfund) reportable quantity (Ibs) (40 CFR 302.4)
None
Superfund Amendments and Reauthorization Act of 1986 (SARA~
Hazard categories Immediate Hazard - Yes I

Delayed Hazard - No
Fire Hazard - No I

Pressure Hazard - No
Reactivity Hazard - No
Section 302 extremely No
hazardous substance (40
CRF 355, Appendix A)
Section 311/312 (40 CFR No
370)
Drug Enforcement Not controlled
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Administration (DEA) (21 CFR
1308.11-15)
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i ENZOL® Enzymatic Detergent CPH MSDS NA

!: MSDS-008 Revision #: G Issue date: 9/14/12 4/ 5
i WARNING: This is a controlled proprietary and confidential document. Verify revision is current prior to use.
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 Canadian regulations This product has been classified in accordance with the hazard criteria of the CPR and the MSDS
contains all the information required by the CPR.
WHMIS status Controlled !

WHMIS classification D2A - Other Toxic Effects-VERY TOXIC

WHMIS labeling

Inventory status
Country(s) or region Inventory name I On inventory (yes/no)*
Australia Australian Inventory of Chemical Substances (AICS) Yes
Canada Domestic Substances List (DSl) ! Yes
II Canada Non-Domestic Substances List (N,DSl) No
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China Inventory of Existing Chemical Substances in China (IECSC) Yes
Europe European Inventory of Existing Cqmmercial Chemical Yes
Substances (EINECS) I
i' Europe European List of Notified Chemic~1 Substances (ELINCS) No
Japan Inventory of Existing and New Ch~mical Substances (ENCS) No
Korea Existing Chemicals List (ECl) Yes
New Zealand New Zealand Inventory Yes
Philippines Philippine Inventory of Chemicals ,and Chemical Substances Yes
(PICCS) I

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United States & Puerto Rico Toxic Substances Control Act (T$CA) Inventory Yes
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*A "Yes" indicates that all components of this product comply with the inventory reqUirements administered by the governing country(s)
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State regUlations This product does not contain a chemical known to the State of California to cause cancer, birth
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defects or other reproductive harn,.
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,, ,' US· California Hazardous Substances (Director's): Listed sU,bstance
· ( ... Subtilisins (CAS 9014-01-1) Listed .
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Mexico regulations This safety data, sheet was prepa~ed in accordance with the Official Mexican Standard
(NOM-018-STPS-2000). '

16. Other Information

HM IS® ratings Health: 1*

Flammability: 0

Physical hazard: 0

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NFPA ratings Health: 1

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Flammability: 0

Instability: 0 I
Disclaimer The information in the sheet was written based on the best knowledge and experience currently
available.

ENZOL® Enzymatic Detergent CPH MSDS NA

MSDS-OOB Revision #: G Issue date: 9/14/12 5/ 5
WARNING: This is a controlled proprietary and confidential document. Verify revision is current prior to use.
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