‫‪File No 5‬‬

‫** نظام االمتحان **‬

‫االمتحان عبارة عن ‪ 150‬سؤال الوقت ‪ 210‬دقيقة‬
‫*اول ‪ 15‬دقيقة تتعرف علي البرنامج اللي هتمتحن عليه‬
‫*اول جزء في االمتحان ‪ 75‬سؤال والوقت ‪ 90‬دقيقة‬
‫*استراحه لمده ‪ 15‬دقيقة‬
‫*تاني جزء في االمتحان ‪ 75‬سؤال والوقت ‪ 90‬دقيقة‬

‫متنساش تذاكر باقي الملفات‬

‫‪1- pharma 700 Qu‬‬
‫‪2- pharma 300 Qu‬‬
‫‪3 – cases‬‬
‫‪4- calculation‬‬
‫كل الملفات هتالقيها علي الجروب‬
‫‪FB.com/groups/pearsonvue.questions‬‬
 New QU 10/2017
1- narcotic iv still effective till :-
a- 12 hours b- 24 hours
c- 36 hours d- 72 hours

2- women with phobia with car which drug is for ttt:

Buspirone (Generalized Anxiety Disorder GAD)

3- Flumazenil with overdose of diazepam with no effect due

to - antidote was small amount

4- Most potent Statin: Rosuvastatin, Pitavastatin and

Atorvastatin

5- which has fastest action diazepam or lorazepam:

lorazepam

6- 48 yrs man he took pneumococcal with influenza

vaccines, which vaccine should take next
a- influenza b- pneumococcal polysaccharide
c- hepatitis B d- MMR

7- Lithium and Gentamicin can be measured and curved

down after: 8 hrs
Therapeutic Drug Monitoring (TDM)

8- GMP in KSA means: good manufacturing practices

establishment of all safety and efficiency of drug manufacture procedure

9- Simvastatin max dose in geriatric:

a- 20 mg c- 40mg
d- 60 mg e- 80 mg

10- Monophasic OCs means :

a-Estrogen b-progestron
c-Estrogen + progestrond

11- Warfarin antidepressant drug interactions :

a- Decrease Warfarin metabolism b- increase plasma level

12- Athlete's foot player treatment:

a-oral anticiotic b-oral antifungal
c-topical antifugal d- topical …. Oil
**NORTE** Antifungal such as Terbinafine (Lamisil®); 250 mg/day
orally once or 2 divided doses for 2-6 weeks

13- Carbidopa and Levodopa contains mainly effect ?

Entacapone which is selectively and reversibly inhibit COMT

14- Potassium channel blockers:

class III antiarrythmia

15- Interleukin I Inhibitor : Anakinra

16- Ciprofloxacin side effects: seizures

17- Cephalosporins side effects : Allergic reactions (cross-

sensitivity) &Hypoprothrombinemia & Mild stomach cramps

18- Cyclophosphamide side effects:

Bladder toxicity (Hemorrhagic_Cystitis)

19- Intermittent cough (asthma) treated with:

Short-acting β2-adrenoceptor Agonists (SABA)

20- Toxin that can be used therapeutically:

a-Botulinum toxin b- x toxin

21- 2 Vaccines (live attenuated and killed ) how can be

administered :
a- at same time b- day after day
c- 2 weaks between them d- monthes between them

22- Phase 3 and phase 4 in cardiac action potential

Phase 3 (Rapid Repolarization K )
Phase 4 (Resting Membrane Potential; RMP)

23- Tyramine not taken with :

Monoamine Oxidase Inhibitors (MAOIs)

24- According to KSA cold preparation; drugs not given to

children less than:
a-2 years b-4 years
c-6 years d-6 years

25- Maximum daily dose of ibuprofen OTC:

a-800 b-1000
c-1200 d-2000
e-3000
** If Q: Maximum dose of Ibuprofen : 3200
26- ttt of hyperkalemia
a- kaylexate b- Na

27- Dose of heparin: 80-100 units /kg

28- Digoxin dose calc should be measure through or post

dose ?
-Through dose , before second dose by half hour
-Therapeutic Drug Monitoring (TDM)
29- types of errors in pharmacy:
a-adminstratin b-dispensing c-ommission

30- Heparin Side effect :

bleeding complicatins & Hyper sensitivity reactions & Thrombocytopenia &
Osteoporosis has been observed in patients on long-term therapy

31- Patient burn hand when cooking:

a-wash with water for 20-30 min b- put ice c-put vasline

32- SE of Lithium:
headache, dry mouth, polydipsia, polyuria, polyphagia
may include ataxia, slurred speech, coarse tremors, confusion, and convulsions,
arrhythmia, hypotention & Teratogenicity with pregnant
33- Nurse give pt dose 2 hrs later what is the type of error:
wrong time errors - administration error

34- Fingolimod which used for multiple scelerosis

must check up of the following: ECG

35- Patient with depression and took amitriptine after

days she felt depreesed Dr should:
a-shift b-double dose
c- add another antidepressant

36- Old patient end stage colorectal cancer take 60 mg

morphine twice . Suffer pain when he go to bathroom. Add
?:
a-Mg b- morphine c-……..

37 Patient second exposure in h. Pylori and there is risk of

resistance he took in first time:
38- Phenytoin suspension dose : 15ml/day or 5 mL (125 mg/5 mL) three times
daily, or one teaspoonful, by mouth 3 times daily. Adjust the dosage to suit
individual requirements, up to a maximum of 25 mL daily

39- Penicillin allergy caused by : IgE

40- according to the saudia food and drug authority cough

medications are contraindicated in children:
A- less than one year B- less than two years
C- less than three years D- less than six years

41- at what age the tuberculosis vaccines (BCG) should be

given:
a- at birth b- 6weeks_2months_4months
c- 2months_4monthd_6months d- 1 year

42-a man travelled to Africa and while he was there he got

ameoba and started metronidazole 500mg three times daily
after 7 days he still have symptoms .what medication can
be added ?
a- vancomycin b- erythromycin
c- diloxanide

43- a child is taking high dose amoxicillin (99mg/kg) for

otitis media came to the clinic for pneumonia and infuenza
vaccine:
a) cancel the vaccines b) proceed to give the vaccines
c) delay the vaccines for one year

44- MMR vaccine is given at what age?

first dose 12months and second dose 4years
45- the cause of diphtheria: corynebacteriam

46- Vit c used for:

a-Coloring agent b-Preservative
c-Tasting agent
47- Alndronate dose per week: 70mg once aweak =10 mg daily

48- Antidot for atropin? : Physostigmine

49- Role of scientific office in pharmaceutical company:

A pharmaceutical establishment that provides scientific, technical and
marketing information on pharmaceutical preparations throughout the
Kingdom.

50- Nilotinib:
Tyrosine Kinase Inhibitor use as
chronic myelogenous leukemia (CML)
gastrointestinal stromal tumors (GISTs)

51- 40 years .playing sport . Dry cough , Weezing , chest

tightness :
a- Laba b- SABA c- Inhaled corticosteroid d-Loncet

52- Dr ask pharmacist about interaction between warfarin

and heparin? Chosse ipnr after how many days and the
test result:
53- Prescription of tramadol written 2days ago in Riyad
and you are a pharmacist in dammam what will you do
a- don't dispense b- call doctor to change drug
c- dispense d- fill 3 days
54- Mechanism of action of sitagliptin:
dipeptyl peptidase no. 4 inhibitor (DPP IV Inhibitor)

55- adanafil effect on pt using nitrate with diabetes is:

non pharmacological treatment

56- most common dispensed in otc : Multi Vitamins

57- drug disponsed to patient and the nurse found that

there was another dose at the patient room so what
should she do :
a- return the dose to the pharmacy
b- keep it to the next dose
c- throw it away

58- one of the OTC : Ibuprofen

59- Misoprostol is used for :

a- prevent ulcer b- prevent and treat gastric ulcer
c- treatment of ulcer

60- A woman with seizure is on valproic acid shes planning

to get pregnant what is the best choice?
a- continue on valproic acid b- stop valproic acid
c- change to levetiracetam
61- which of these laxatives have the lowest onset of
action:
a- milk of magnesia b- glycerin
c- Biscodyl d- psyllium

62- A patient with a gastric ulcer caused by h.pylori and

started on triple therapy ( clarithromy, metronidazole
,ppi)but his symptoms not improved because of
bacterial resistant :
a- (clarithromycin, amoxicillin,ppi)
b- (bismuth, tetracycline, metronidazole ,ppi)
c- (bismuth, doxycycline, metronidazole,ppi)

63- at what time 99% of the drug will be cleared from

the plasma:
a- 4.5 t half b- 6.6 t half
c- 7.4 t half

64- What is the meaning of pregnancy category B :

Animal reproduction studies have failed to demonstrate a risk to the fetus
and there are no adequate and well-controlled studies in pregnant women.

65- validity of Pharmacy permit :

a-1 year b-3 years
c-5 years d-10
66- MMR vaccine is given at what age :
first dose 12months and second dose 4years

67- when we should stop plavix before cardiac surgery :

5-7 Days

68- in which muscle we give vaccine for infants :

The vastus lateralis muscle in the anterolateral thigh

69- -which of this lowest potency laxative :

a- glycrine b- magnesium milk
c- bisacodyl

70-Pharmacy regulation & guidlines is comming from:

a-MOH b-SPA
c-sFda d-scfhs
‫ موجوده بيقي هي الصح‬General Pharmaceutical Council GPhC)( ‫لو‬
71-therapeutic equivalent dose of omeprazole 20 is:
a- cimetidin 800 mg b- esomeprazole 40 mg
c- ranitidine 300 mg d- pantaprazole 40 mg

72-dose of ferrous sulfate: 300 B.I.D

73- which NSAID has more enterogenic effect

a- Piroxicam b- Naproxen c- Dicofenac d- Ibuprofen

74- physician prescribe Amoxicillin if you don't have the

brand what you will do: a-
Will you give the generic b- send him an other pharmacy
c- tell him you dont have the medicine

75- child receive high dose Amoxicillin for otitis and he has-
appointment for vaccine what we do shall we postponed
the vaccination ?: NO
76- child receive short acting b agonist without
improvement then he develop cough with wheeping what is
the treatment: a- Amoxicillin b- azithromycin
c- steroid

77- pt was treated with Fluoxetine without improvement

after how many weeks: you shift him to anther group

78- Warfarin and heparin was prescribed to pt in hospital

how long he will take the heparin and how much the INR :
Take heparin for 2 days with warfarin then stop heparin , warfarin biological t/2
after 48 hours

79- Total knee replacement which anticoagulation he

should continue:
a- asprin b- enoxaparin c-Clopidogril

80- Pseudoefedrine is: a-

antiallergic b- decongestant

81-20 mg omeprazol equal to which doses of pantoprazol or

ranitidin in the H.Pylori treatment: pantaprazole 40 mg
82- Pt with Prostate hyperplasia and dysuria what
medication u will give :

83-35years BMI35 , (Oral contaceptive)?:

Only progesterone pill

84- Baby with immunedeficiency syndrome took

immunoglobulin which vaccines is C.I:
a- mmr b- rubella c- meningitis d- rotavirus (RV)

85- Baby with fever & tugging ear. Doctor exclude bacterial
infection : (amoxicillin with different doses + antiviral i do not remember)

86- Calculate cr.cl age 40 &weight 80 &sr.cr=0.5 Result mg

/ml For
male
- For female = CrCl of male x 0.85

87- what is the treatment of keto acidosis :

-Correction of fluid loss with intravenous fluids

-Correction of hyperglycemia with insulin

-Correction of electrolyte disturbances, particularly potassium loss

-Correction of acid-base balance

-Treatment of concurrent infection, if present

88- what should be monitored when giving patient lithium

therapy:

89- Liraglutide MOA:

Liraglutide (NN2211) is a derivative of human incretin (metabolic hormone) glucagon-like
peptide-1 (GLP-1) that is used as a long-acting glucagon-like peptide-1 receptor agonist,
binding to the same receptors as does the endogenous metabolic hormone GLP-1 that
stimulates insulin secretion.
90- child weight 16 kg and length 92 cm calculate the body
surface area ?

so BSA(m²)= SQRT (92x16)/3600

= SQRT (.48555)

=.69681 m²

91- Anti metabolite cause bone marrow suppression:

a- Azathioprine b- Methotrexate

92- Relation between autism and vaccine:

Relation between autism and MMR vaccine ?? No relation
Relation between autism and thimerosal vaccine ?? relation
93- Urine incontinence drugs for urge conditions?:
-Anticholinergic medications
-Mirabegron (Myrbetriq)
-Ona botulinum toxin type A (Botox)
94- Body mass index and body surface area calculation:

95- Duration of using domperidon 6–8 hrs

96- Duration of esomeprazole in gastroesophagial disease:
up to 24 hrs

97- Drug and dose of Infant with mild fever:

paracetamol 1 gm per day
98- Antibiotic cause hyperkalemia:
trimethoprim
99-Selective estrogen receptor modulator ( SERM):
tamoxifen

100- Masking acidic taste of syrup use which flavor:

strong base anion‐exchange resins

101- Dose of enxaparine in male with DVT1.5 or1 rout IV or

IM: ‫ اعتقد االجابه هي‬SC

102- organophosphorus toxicity removed by:

a-gastric lavage b-paralidoxime
c- charcoal d- hemodialysis

103- Reduce gastric side effect of metoformine administer

metoformine. .......?:
biggest complaint people have about Metformin is that it causes gas and
diarrhea. This can often be reduced by increasing the dose gradually
104- Dispense a prescription of diazepam for:
a- 7days b- 14 days c- 30 days

105-A man with hypertension and myocardial infarction his

medications are metoprolol and nitroglycerin for his MI he
present to the clinic with erectile dysfunction what
medication is the most appropriate for his erectile
dysfunction:
a- sildenafil b- avanafil c- no pharmacological treatment
106- Antiarrhythmic drug cause iodine hypothyroidism :
amiodarone

107- Metformin avoiding its side effect of N, V:

Metformin nausea and vomiting may be asign of lactic acidosis.And treatment is :
treating Lactic acidosis sometimes represents a medical emergency. Increasing
oxygen to the tissues and giving IV fluids are often used to reduce lactic acid
levels. Electrolyte-replacement sports drinks such as Gatorade help with
hydration, but water is usually best.

108- Pt taking prazocin , want to give him tadalafil , want

the time duration bet them: 4 hours
109- patient is on Omeprazole and it's expired what you
advice her?:
a- she can take it if it was stored properly
b- buy a new one

110- Anti hypertension drug safe in pregnant?: labetalol

111- pt take morphen and we want replace by Fentanyl ?:
Fentanyl is 50 to 100 times more potent than morphine (80)
112- Removing a drug from formulary:
pharmacy therapeutic committee
113- Anti hypertensive drug... can affect fetal growth:
a- Amlodipine b- hydrochlorothiazide c- lisinopril

114- Diuretic side effects are ototoxicity and deafness:

a- frusemide b- triamterene c- hydrochlorothiazide
115- Food that should be avoided when taking amiodarone:
grape fruit
116- The meaning of compassionate drug use:
use a drug that not approved yet (new unapproved drug)
117- Overlapping of clexane with warfarin:
At least 5 days

118- Voriconazole dose is adjusted in hepatic impairment:

100 mg/ twice daily
119- Chlild with otitis media with QT prolongation , which
abx is CI: azithromycin
120- Mechanism of action of (aliskiren):
Aliskiren (trade names Tekturna and Rasilez) is the first in a class of drugs
called direct renin inhibitors. It is used for essential (primary) hypertension.
121- Lamotrigen we start with small doses then
increase(reson):
to prevent develop of serious Rash.

122- When Women start folic acid :

- before pregnancy with one month and 1st trimester.
123-Dose of enoxaparin in knee replacement:
30 mg SC q12hr; initiate therapy 12-24 hr postoperatively and continued for
10 days or up to 35 days postoperatively or until risk of DVT has been
significantly reduced or patient is on anticoagulant therapy

124- terazosin Mechanism of action :

selective alpha-1 antagonist

126- maximum dose of Phyntoin: 300mg/d

127- what enzyme we used for acute leukemia :

L-Asparaginase enzyme

128-Cetirizine MOA-: H1 blocker

129- MMR is : mixture of live attenuated viruses

130- Pilocarpine : medication used to treat open angle glaucoma

131- Sevelamer: decreases serum uric acid concentration .

132- bone marrow suppression :
a- Vincristine b-Ergot c-L-aspiregase d- doxorubicin

133- Vincristine adminstration:

by minibag (IV push) or infusion (IV)

136- simvastatin daily dose for pt hypercholestrolemia:

a- 20 b-40 c-60 d- 80

132- zolpidem maximum dose:

a- 5 mg/d b-10 mg/d c-15 mg/d d-20 mg/d

134- labetalol M.O.A:

135- Montelukast MOA :

Leukotriene antagonists
*NB*
used for the maintenance treatment of asthma and to relieve symptoms of
seasonal allergies. It is usually administered orally.

136- dosage form preferred for children : Oral

137- Biosimilar means:

is a biologic medical product which is almost an identical copy of an original
product that is manufactured by a different company.[1] Biosimilars are
officially approved versions of original "innovator" products, and can be
manufactured when the original product's patent expires.

138- Proton Pump Inhibitors MOA:

inhibitors act by irreversibly blocking the hydrogen/potassium adenosine
triphosphatase enzyme system (Inhibitors of the H+/K+-ATPase proton pump)

139- Example of drug disease interaction:

pioglitazone and heart failure

140- speed of response of receptors ( receptor response in

milliseconds and other receptor response in seconds :
a- voltage gated receptors and ligand gated receptors
b- voltage gated receptors and G _ protein receptors
c-ligand gated receptors and G _ protein receptors
d- ...........................................

141- Which solution is isotonic

a- dextrose 5% b- saline 3%
c- ringer solution d- ....................

142-(case) is taking doxycycline for acne and doctor prescribe

adapalene for topical use and doxycycline for systemic use
and he suffer from heartburn you advised him to :
a- take omeprazole with doxycycline b- stop adapalene
c- apply adapalene as thin layer

143- smoker man which drink coffee , take steroid drug ,

married to two wifes , how many factor effect ulcer :
a- 1 b- 2
c- 3 d-4
144- MAO inhibitor drug inhibited with cheese:
a- linezolide b- tranylcybromine

145-Side effects of enoxaparin

A- hypokalemia B- hyperkalemia
C- hypocalcemia D- hypercalcemia

146-malignant hypertension treatment :

intravenous sodium nitroprussideinjection,
In less urgent cases, oral agents like captopril, clonidine, labetalol,
or prazosin can be used, but all have a delayed onset of action

147- (Case)diabetic patient needs drug for

hypertriglyceridemia
a- statin b-glifibrozide
c-cholestyramine d- Eztimibe

148- Antipseudomonal Drug

a- nafcillin b- Merobenem

149- (case) with upper respiratory tract .. penicillin sensitivity

a- cephradin b- cephdinir
c- ciprofloxacin d- clindamycin

150- Drug for Myasthenia gravis : pyridostigmine

151- Phentolamine MOA : -α Adrenergic Antagonists

152- (Case) addictive driver challenge police , talkative ,

aggressive .. addiction of :
a- amphetamine b- morphin saline 3%
c- cannabinoid d- LSD

153- (Case) had accident .. phobia from cars .. treated with

Anxiolytic .. she takes also cimetidine for hyperacidity .. she
become phobic when takes cimetidine .. why ?
a- cimetidine decrease excretion
b- cimetidine increase metabolism of anxiolytic

154- (Case) Woman wants the prescription of her drug

because her case is like his case as she said what will you
do:
a- give her the prescription
b- give her the bottles of drugs in the prescription
c- prevent her from taking it without her brother approval
d- give her the telephone of the prescriper doctor

155- (Case) girl has epilepsy .. taking valproic acid and it's
control the disease she planned to be pregnant and she
already takes folic acid what to do:
a- shift from valproic acid to phenytoin b- keep her using valproic acid
c- give her leviteracetam and decrease valproic acid till epilepsy is well
controlled then discontinue

156-(Case) car driver wants Antihistaminic: desloratidine

157- Minoxidil is : arteriodilator only

158-What is the time interval between two drugs if half life

time is 4 hrs : 8 hrs
159- Example of error of deteriorating drug:
example of giving expired drug

160- What's the five right of drug administration

the right patient, the right drug, the right dose, the right route, and the right
time

161-(case) of hypertension patient takes 40 mg Lisinopril and

10mg carvedilol he has normal heart rate but hypotension
after drug administration
a- stop Lisinopril b- decrease dose of Lisinopril
c- decrease dose of carvedilol d- stop carvedilol

162-(case) pt go to doctor and his blood pressure is high then

after that he measure the pressure after that but his blood
pressure is normal . the doctor prescribe two
antihypertensive drugs although its pressure is normal at
last times he prescribe:
hydrochlorothiazide and spironolactone

163- base that use in suppository : cocoa butter

164- dose of zaleplon as sedative:

165-(case) Someone has cold symptoms and he has drug A

contains pseudo ephedrine and chlorpheniramine maleate
and drug B contains pseudoephedrine with loratidine you
advised him sensitivity:
a- use both of them as they have same efficacy
b- use one of them as they are the same brand
c- take drug B as it has more benefits
d- don’t use any one of them

166-(case) patient take ciprofloxacin you advised him to:

a- administer hour before and two hours after phosphates administer
b- administer ciprofloxacin with food

167- taste disturbance caused by drug :

a- verapamil b- captopril
c- …………….

168- more important mentalic multivitams:

a- cobalt b- iron
c- beta carotin
169- hydralazine mechanism of action:
smooth muscle relaxant and cause arteries and veines dilation and relaxation

170- labetalol M.O.A :

is a dual alpha (α1) and beta (β1/β2) adrenergic receptor blocker and competes
with other Catecholamines for binding to these sites

171- role of GMP:

GMP (Good Manufacturing Practice) is part of a quality system covering the manufacture and
testing of pharmaceutical dosage forms or drugs and active pharmaceutical ingredients, diagnostics,
foods, pharmaceutical products, and medical devices. GMPs are guidance that outlines the aspects of
production and testing that can impact the quality of a product.

172- Drug which increases the action of warfarin:

a. Carbimazole b. Oral contraceptive
c. Phenobarbitone. d. None of the above

173- (case) woman take levothyroxine 50 and she become

pregnant and she feel fatigue :
a- don’t change dose coz fatigue is normal sign in pregnant
c- increase levothyroxine dose

174- Duration of domperidone: 3-5 days

175- pt take fluoxetine but no effect doctor want to change

drug by phenelzine .. when pt initiate to take phenelzine :
a- 2 weeks b-3 weaks
c- 4weaks d-5 weaks

176- Avanafil is a PDE5 inhibitor approved for erectile dysfunction

177- doxycycline↓GIT Side Effect by : drink large amount of water

178- Patient has psychosis and he agreed to take a
medication which has the lowest hypnotic effect .. What is
it: a- Clozapine b- Olanzapine
c- Respeidone d- Quitabine

179- treatment of pulmonary tuberculosis must be

continued for at least :
a- 6 months b- 4 months
c- 2 months d- a month

180- In secondary hypertension pt which combination is

best her : ACE inhibitor + CCB + thiazide
181- Prophylaxis of migraine : Sufficient evidence and consensus
exist to recommend propranolol, timolol, amitriptyline, divalproex, sodium
valproate, and topiramate as first-line agents for migraine prevention.

182- which is Controlled drug:

a- Fentanyl b- sitagliptin
c- Dextromethorphan d- atenolol

183- which of the following is a high alert solution:

a- Ringer b- Dextrose 20%
c- Saline d- Parenteral nutrition

184- Anti-deprssant taken to woman with seizures :

a-paroxetine b-fluoxetine
c-bupropion d-sertraline

185- Category A drug in pregnancy means :

a- no evidence of any risk on human
b- no evidence of any risk on human and animals
186- In USA,,tablets must be uniform in order to perform :
a- bioavailability b- safety
c- absorption

187- Infant with croup what virus u suggest he has :

a- rotavirus b- parainfluenza
c- pneumonia

188- Dose of digoxin is :

-oral : 0.125- 0.5 mg/d
-IV/IM : 0.1 – 0.4 mg/d

189- (calc) want to prepare 60ml of 15% liquid .. and we have

30% how many ml of stoke to be taken ??
15 g ---> 100 ml
X g ---> 60 ml X = (60 x 15 )/ 100 = 9 garms
…………………………….
30 g ---> 100 ml
9 g ---> Y y = (9 x 100) / 30 = 30 ml
190-Old man will be on simvastatin and he is on verapamil
what dose of simvastatin will be appropriate :
a- 10 mg/d b- 20 mg/d
c-30 mg/d d- 40 mg/d

191- Sever case of Alzheimer we give :

a- donepezil b- Memantin

#Donepezil is the only cholinesterase inhibitor approved to treat all stages of

Alzheimer's, including moderate to severe.

192- drug treat extrapyramidal for 70 y old :

a- benztropin b- haloperidol
c- memantin

193- drug cause change in Mental Status :

a- diazepam b- sertraline

194- pt have kidney failure not give : Indomethasine

195 – which is fast absorption :

a- Oral b - Rectal
c- Subcutaneous d Topical
196- Ca carbonate side effect :
a- Constipation b- Salivation
c- increase in weight d- Hypercalcemia

197- one drop has a volume of :

a-0.5 ml b-1 ml c- 1.5 ml
d- variable , depending on the liquid and the dropper

198- Best counseling point for patients taking warfarin :

a.Avoid grapefruit b.No caffeine
c. Vit K consistent d.Use sunscreen

199- drug use in ER:

a- Lorazepam b- Diazepam

200- which antiemetic we can use it for pregnant : cyclizine

o Cyclizine
o Diphenhydramine (Benadryl)
o Dimenhydrinate (Gravol, Dramamine)
o Doxylamine
o Meclizine (Bonine, Antivert)
o Promethazine (Pentazine, Phenergan, Promacot) can be administered
o via a rectal suppository for adults and children over 2 years of age.
o Hydroxyzine

201- Pharmacoviglance :
Postapproval standing seientific and data gathering activities related to the
detection, assessment ,understanding and prevent s.e.

202- Use Metformin to avoid get side effect :

a- Take after meal by 2 hr b- take divided dose with meals
c- Take the dose with food
203- (Case) A child swallowed 100 capsules of iron each
capsule contains 18 mg no signs and symptoms so the ttt
is:
a- activated chatcoal
b- activated charcoal double dose
c- Gastric lavag

204-In USA,,tablets must be uniform in order to perform:

a- bioavailability b-safety
c- absorption

205- Benzoyl peroxide MOA in acne:

a-Keratolytic b-Antifungal
c-Antibacterial

206- Max duration of domperidone therapy:

a- 5 days b- 7 days
c- 10 days d- 14 days

207- A nursing women was taking a drug and caused

decrease in the milk what drug can decrease the milk :
Drugs inhibit lactation :
-ethinylestradiol ( Estrogens)
-ergometrine ( Oxytocics)
-chlorphenamine ( ANTIALLERGICS)
-levodopa + carbidopa (ANTIPARKINSONISM DRUGS)
-amiloride ( diuretics)
-furosemide ( diuretics)
-hydrochlorothiazide ( diuretics)
-ethinylestradiol + levonorgestrel (Hormonal contraceptives)
-ethinylestradiol + norethisterone (Hormonal contraceptives)

208- Anticoagulant with hemodialysis :

a- Heparin b-Clexan
c- clapidogrel d- Aspirin

209- What's Your advice to patient uses isosorbide dinitrate

for angina :
a- to chew and swallow tablet
b- If the pain not relieved after two minutes to go to emergency department

210- A woman has high level of T3 and T4 and normal level

of TSH .. give her :
a- levothyroxine b- methamizol

211- neonate came to the clinic with fever, persisting

cough, nasal discharge which diagnosis :
a- pneumonia b- laryngitis
c- pharyngitis

212- which your advice to pt take fentanyl patch:

*Get emergency medical help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.

*Remove the skin patch and call your doctor at once if you have any of these
serious side effects:

• slow heart rate, weak or shallow breathing, sighing;

• confusion, hallucinations, unusual thoughts or behavior;
• severe weakness, feeling like you might pass out;
• cold, clammy skin; or
• pale skin, easy bruising or bleeding

-Do not use this medication unless you are already being treated with a similar opioid
(narcotic) pain medicine and your body is tolerant to it.
-Do not expose the skin patch to heat while you are wearing it.
-Keep both used and unused fentanyl transdermal patches out of the reach of
children or pets. The amount of fentanyl in a used skin patch could be fatal to a child
or pet who accidentally sucks on or swallows the unit
***more infotmation about Use of Fentanyl Patches on this link***

https://www.palliativedrugs.com/download/08_09_Fentanyl%20Patches.pdf
214- "off label" meaning:
"Off-label" means the medication is being used in a manner not
specified in the FDA's approved packaging label (unapproved)

215- Aspirin dose with ticagrelor :

Administer with aspirin: Initial loading dose of 325 mg, then maintenance dose of aspirin of
75-100 mg/day; DO NOT exceed aspirin dose of 100 mg/day .

Source: http://reference.medscape.com/drug/brilinta-ticagrelor-999674

216- MOA of Memantine :

MOA: Open channel block of NMDA receptors. Prevents Na+ and, more
importantly, Ca2+ entry into theneurone, so reducing glutamate excitotoxicity.
Normal glutamatergic transmission continues.

217- which increase absorption of iron : Vit C

A higher bioavailability of the dietary iron can be achieved by increasing the
content of food components enhancing iron absorption (ascorbic acid, meat/fish)
or by decreasing the content of inhibitors (e.g., phytates, tannins).

https://www.ncbi.nlm.nih.gov/pubmed/2507689

218-Most likely to interact with statins:

a- Nitrofurantoin b- Amoxicillin
c- Fosfomycin d- Daptomycin

statin, daptomycin. Either increases toxicity of the other by

Other .Modify Therapy/Monitor Closely.

Comment: Coadministration of daptomycin with HMG-CoA

reductase inhibitors may increase CPK levels and risk for
myopathy; consider temporary suspension of HMG-CoA
reductase inhibitors during daptomycin therapy.
219- Which medication would you avoid administering with
calcium:

a- Amoxicillin b- Ciprofloxacin
c- Macrobid d- Ibuprofen

220- Which med should be avoided in a patient with a true

sulfa allergy :

a- Septra b- Vancomycin
c- Ceftriaxone d- Clindamycin

221- Which of the following is a benzodiazepine :

a- Linzess b- Chlordiazepoxide
c- .Mechlorethamine d- Chlorhexidine

222- Celexa (citalopram) is an SSRI – Max recommended

dose in the elderly (>60) is 20 mg daily due to potential QT
prolongation

Which can be problematic with iron supplementation in the

elderly?
a- Absoprtion b- Elimination
c- Distribution d- Metabolism

223-MOA of terazosin :
a- Increase nitous oxide b- Blocks alpha receptors
c- Blocks beta receptors d- Calcium channel blocker
224- pt have green sputum which anti cough can be give:
Guaifenesin such as robitussin , mucinex

225- which is the pt with multiple prescription not take

OTC:
a- adult b- pediatric
c- children d- geriatric

226- child have nisseria what is the precautions :

isolate to prevent transmission of infectious agents and prevent
transmission of pathogens spread through close respiratory or mucous
membrane contact with respiratory secretions

227- stop in lactation:

a- anti-cholinergic b- anti-muscarinic
c- antihistamine

228- pt take alprazolam and verapamil which your advice:

Verapamil increase level of alprazolam so we decrease
dose of alprazolam

229- girl came to the pharmacy with her brother drugs say
need same drugs:
a- Print prescription for her b- Send her to the doctor

230- drug avoiding taking with tyramine:

a- linezolid b- warfarin
c- prednisolone d- ketoconazole

231- Antibiotic cause hyperkalemia:

a- Trimethoprime b- Sulfamethoxazole
232- The bioavailability of diclofenac injections is muscle
injection:
a- 25% b- 50%
c- 75% d- 100%

233- Pt. Take levothyroxin when he can monitor after:

a- 1 weak b- 2 weaks
c- 3 weaks d- 4 weaks
‫ اسابيع لكن مش موجوده في االختيارات‬8-6 ‫االجابه المفروض تكون من‬

234- Case pt needs drug for hypertriglyceridemia:

a- atrovastatin b- Gemfibrozil
c- Ezitimibe d- Cholestyramine

235- Case diabetic pt needs drug for hypertriglyceridemia :

a- atrovastatin b- Gemfibrozil
c- Ezitimibe d- Cholestyramine
236- case geriatric pt + back pain + high LDL+ DM which
analgesic can give to him?: Acetaminophen

237- GAD work as :

Glutamic acid decarboxylase (GAD) is the enzyme responsible for the
synthesis of gamma-aminobutyric acid (GABA). GABA is an important
inhibitory neurotransmitter in neurons and beta pancreatic cells. The two
isoforms in glutamic acid decarboxylase are identified as GAD-67 and
GAD-65. Both isoforms are present in both the brain and pancreas.

238- Dose of enoxaparin in DVT treatment :

A- 1.5 mg/kg SC every 12 hr B - 1 mg/kg SC once daily
C- 1 mg/kg SC every 12 hr D- 1.5 mg/kg SC once daily

239- Case condition in which the symptoms of

hypothyroidism:
levothyroxine

240- Vaccine contra indicated in pregnancy:

241- live vaccine :
List of live vaccines 
- Influenza intranasal - Measles - Mumps
- Polio Sabin - Rotavirus - Rubella
- Tuberculosis (BCG) - Varicella - Yellow Fever

242- Levothyroxin dose in geriatric :

Mild Hypothyroidism
1.7 mcg/kg or 100-125 mcg PO qDay; not to exceed 300 mcg/day
>50 years (or <50 yr with CV disease)
• Usual initial dose: 25-50 mcg/day
• May adjust dose by 12.5-25 mcg q6-8Week
>50 years with CV disease
• Usual initial dose: 12.5-25 mcg PO qDay
• May adjust dose by 12.5-25 mcg q4-6weeks until patient becomes euthyroid and serum
TSH concentration normalized; adjustments q6-8weeks also used
• Dose range: 100-125 mcg PO qDay

Severe Hypothyroidism
Initial: 12.5-25 mcg PO qDay
Adjust dose by 25 mcg/day q2-4Week PRN
Subclinical Hypothyroidism
Initial: 1 mcg/kg PO qDay may be adequate, OR
If replacement therapy not initiated, monitor patient annually for clinical status
243- Zolpidam max daily dose :
Immediate-release tablet, sublingual tablet, and oral spray
• Dosing for PO (Ambien), SL (Edluar), and oral spray (Zolpimist)
• Women: 5 mg PO/SL/oral spray qHS
• Men: Consider 5 mg PO/SL/oral spray qHS; may use 10 mg PO/SL/oral
spray qHS if needed
Extended-release (Ambien CR)
• Women: 6.25 mg PO qHS
• Men: Consider 6.25 mg PO qHS; may use 12.5 mg PO qHS; not to
exceed 12.5 mg/day
Source: http://reference.medscape.com/drug/ambien-cr-zolpidem-342931#0

NB q.h.s. = at bedtime

244- test for renal function :

a-Cr.cl. b- Bun.
c- urea . d- serum creatine
‫االختيارات كلها تنفع بس االكثر استخدام فيهم‬
serum cr.

245- DOC for pneumonia :

246- digoxin cause :

a-hypokalemia b- hyperkalemia
c- hypercalacemia

247- anti depressive should be taken to a woman with

seizures:
a-Buprion b- Fluxetine
c- Paroxetine d- Sertaline and citalopram
248- paracetamol is hepatotoxic due to its action on:
a-Glutathione b- Liver enzymes

249- analgesic considered as narcotic but dispensed

normally:
a-Naproxen b- Methycodone
c- Ketorolac

250- drug treat extrapyramidal for 70 y old:

a-Benztropin and diphenhydramine ,trihexyphenidyl
b- Haloperidol.
c- Memantin

251- what is the category of Lisinopril in pregnancy :

a- category B b - category C
c- category D d- category X

252- Lisinopril Contraindications in: Angioedema history patient

Lisinopril Contraindications
Hypersensitivity to lisinopril/other ACE inhibitors
History of ACE inhibitor-induced angioedema, hereditary or idiopathic angioedema
Coadministration of neprilysin inhibitors (eg, sacubitril)
Coadministration with aliskiren in patients with diabetes mellitus or with renal
impairment (ie, GFR <60 mL/min/1.73m²
http://reference.medscape.com/drug/prinivil-zestril-lisinopril-342321#5

253- Most important in constipation patients :-

A- daily take of water . B- Go bathrooms morning daily for 30 min
C- decrese fiber intake

254- Code of ethics in KSA :-

With the beginning of drug registration and follow-up throw the Saudi Food and Drug
Authority,the authority have introduced qualitative step by obligating the Scientific
offices of pharmaceutical companies to follow the terms of Saudi Arabian code of ethics
for marketing practicing of Saudi pharmaceutical products In Kingdom of Saudi Arabia
255- Po meaning: drug take by mouth

256- HTN drugs : must taken graduly

257- Clozapine cause : agranulocytosis

258- Best way to use NSAIDS :

a- WITH food and milk to decrease git upset
b- after meal

259- Pylonehritis pregmant woman treatment :

Amoxicillin- clavulanate 500/125 mg orally twice daily for 3-7 days

260- Streptokinase used in : Myocardial Infarction and Clot lysis

261- Nilotinib used in : philadelphia myelogenous leukaemia

262-Which need monitoring ( Low molecular wight heparin ):

a- LMWH SC b- LMWH IV

263- Patient take Mycophenolate and she want to be

pregnant , What is your advise :-
A- Continues use Mycophenolate
B- Stop Mycophenolate before 2 weeks of trying to be pregnant
C- Stop Mycophenolate before 6 weeks of trying to be pregnant

It is known that mycophenolate products can cause birth defects in the unborn
baby of mothers who are, or have recently been, taking mycophenolate. It is for
this reason women are advised not to become pregnant whilst taking
mycophenolate and for 6 weeks after stopping.
source: Oxford Transplant Centre/Oxford Kidney Unit

264- Cyproheptadine in which calss of drug? :-

a- antihistamines b- antibiotics

265- Codeine may used as :- Cough suppressant

266- Patient take valporic acid and have to start take

Lamotrigine What is maximum initial dose of Lamotrigine:
a- 200 b- 300
c- 400

267- Drug cause Ototoxicity in high dose :- Amikacin

268- Patient had depression and take St. John warts,

which drug interact with : sertraline
269- pain killer classified to narcotics drugs and in green
line :
a-Oxycodone b- gabapentin
c- Naproxin

270- Case of 45y patient with kidney failure from 2y ago

with increased K &life threatening arrhythmia, the patient
should be treated with:
A- calcium chloride IV b- calcium carbonate IV
c- insulin 10 units d- resin

271- side effect of NSAID in 3 trimester on fetus :

increase in the risk of premature ductal closure

272- loperamid which recaptor block:

loperamide act on Mu receptor

273- Rivastigmine MOA:

a reversible cholinesterase inhibitor

Although the precise mechanism of action of rivastigmine is unknown, it is thought to

exert its therapeutic effect by enhancing cholinergic function. This is accomplished by
increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis
by cholinesterase.

274- Amphetamine MOA:

Sympathomimetic amine that promotes release of dopamine and norepinephrine
from their storage sites in the presynaptic nerve terminals.
275- Neonatal bronchiolitis treatment:
ventilation and supportive iv nutrition

276- Antidote of Methotrexate ( MTX) : Leucovorin

There are three antidotes that have been used for MTX toxicity: leucovorin,
thymidine and glucarpidase.

277- Varicella cause : Chickenpox

278- Patient identification by : Name and medical record numbe

279- Aptamer for macular degeneration : Pegaptanib

280- What is NSAID that permanently inhibit thromboxane

A2 :
a-Aspirin b- Celecoxib
c- Piroxicam d- Naproxen

281- What is the narcotic that might be used in ttt of

narcotic addiction:
a-Morphine b- Hydrocodone
c- Pethidine d- Methadone

282- what should be monitor when use ppi : PH- Monitoring

To avoid osteoporosis bone fracture add vit B12, vit D and Ca to the
patient in long term treatment .
283- mange of patient with h. pylori:
Vit D and Ca should be added to patient.

284- drug dispense in OTC and use for cough

Suppressant:
Dextromethorphan
NB 
Oxycodone and Dextromethorphan dispense OTC and use for
cough Suppressant.

285- drug mask hyperglycemic effect :

Information 
- Metoprolol - Atenolol -Carvedilol -Clonidine
-Propranolol -Nebivilol -Nadolol -Timolol

286- Aliskiren Contraindications :

Information 
-Furosemide -ketoconazole -nifedipene -vastatine
-ator -apirin -sildenafil -celecoxib

287- first choice of drug for patient in prehyperteintion:

Diuretic

288- what the intervintion to take to patient have erectil

dysfunction , Diabetic , HTN: Sildenafil
289- which drug use to lactating mother for nausea and
vomiting : Domperidone & Meteclopramide

290- women have chronic shortner of breath which

medication use: Cortisone

291- antiparkinson act on any area of brain:

Substantia nigra

292- Patient with left ventricular dysfunction (ejection

fraction > ( number not remember),He developed
dyspnea and make difficult for him in daily life ,,, it cause
by :
B2 blocker

293- Most drug used in immune suppression:

Cortisone

Current treatments for immunological disorders are nearly all empirical in

origin, using immunosuppressive drugs identified by screening large numbers
of natural and synthetic compounds. The drugs currently used to suppress
the immune system can be divided into three categories: first, powerful anti-
inflammatory drugs of the corticosteroid family such as prednisone; second,
cytotoxic drugs such as azathioprine and cyclophosphamide; and third, fungal
and bacterial derivatives, such as cyclosporine.
294- Iodine contrast medium for Patient who have
diabetes and take Metformin , Glipizide and have normal
renal function :

Stop taking Metformin before the exam and not to begin using
it again until 48 hours after exam.

295- Bad effect on heart : Long Acting Beta Agonists (LABAs)

296- Drug not pass placenta : Insulin

297- Mania TTT: Physiologically lithium

298- case pt feeling pain +MI .. He is already taking

paracetamol what should give him: Morphin

299- Case pt arrhythmia + high k what we give him :

Ca gluconate

300- Which Benzodiazepine cause irritability : short acting

301- HTN pt. 170/90 Dr.wrote combination what is it :

ACEI+ loop

302- Recently intered the green list and considered

narcotic drug : Gabapentin

303- Side effect with use of combination of

contraceptives:
Information 
Acne
SE is: Acne, PCOS , PDMM, endometriosis ,Premenstrual dysphoric disorder (PMDD)
,Polycystic Ovary Syndrome (PCOS)
304- Clomiphen:
Clomiphene is a non-steroidal fertility medicine. It causes the pituitary gland to
release hormones needed to stimulate ovulation (the release of an egg from the
ovary).
Clomiphene is used to cause ovulation in women with certain medical conditions
(such as polycystic ovary syndrome) that prevent naturally occurring ovulation.

305- L-dopa effect:

The main function of L-Dopa is as a precursor to several different neurotransmitters,

especially Dopamine.
The Dopamine chemical cannot itself cross over the blood-brain barrier and must be
synthesized in the brain.
However, L-Dopa can penetrate this barrier and leads to increased levels of this
pleasure-inducing hormone. L-Dopa is converted into Dopamine by the DOPA
decarboxylase enzyme, also known as aromatic L-amino acid decarboxylase.
Another necessary component of this process is Vitamin B6 (Pyridoxal phosphate)
which is often stacked with L-Dopa supplements for increased conversion efficiency.
306- Patient have diabetes and he ask if her brother use
the same needle:
Can't share needle

307- Nurse want dose in syringe how can pharmacist

dispensing the dose :
a- Despens syringe with out needle
b- Despens syringe with 60ml
c- In vial and she despens when reach bedside
d- Give her mini-bag instead of syringe
308- When expire date for drug end in December :
31 december

309- Child patient start course of antibiotics he take the

drug for seven days and still one dose and he have to
take vaccine: Take vaccine immediately

310- TTT open angle glaucoma in pregnant:

Brimonidine

311- The mother has infection when she delivered her

baby he come with fever ...etc which antibiotic should
baby take:
a-Gentamicin & ampicillin b- Gentamicin
c-Ampicillin d- Clindamycin

312-effect of finesteride on pregnancy :

abnormalities of the external genitalia

313- side effects of phenytoin :

Side effects of phenytoin include: congenital anomalies. Other side effects include:
hepatic necrosis, ataxia, confusion, constipation, depression, dizziness, drowsiness,
fatigue, hypertrichosis, mental status changes, myasthenia, nervousness, numbness,
tremor, tremor of hands, vertigo, excitement, irritability, mood changes, and
restlessness.

314- Ibuprofen how to take:

a-With food & milk b- After food by 2h
c-Before food by 2h d- With fatty acid

315- Zolpidem side effect :

Drowsiness , Dizziness, Headache, Muscle aches , Sleepiness or

316- Zolpidem use:
Is a sedative-hypnotic drug that is used for short-term treatment of
insomnia

317- Acute ischemic stroke treatment:

The goal for the emergent management of stroke is to assess the patient’s
airway, breathing, and circulation (ABCs); stabilize the patient as necessary;
and complete initial evaluation and assessment, including imaging and
laboratory studies, within 60 minutes of patient arrival . A Finnish study
demonstrated that time to treatment with fibrinolytics can be decreased
with changes in EMS and ED coordination and in ED procedures for treating
acute stroke patients.
https://emedicine.medscape.com/article/1916852-treatment#d10

318- old woman with Alzheimer take medicine make her

vomiting and nausea :
Rivastigmen( Exelon patch)

319- whats the toxic when breakup of sustained release

drug:
multidose toxicity

320- treatment of gout attack in 24h:

Indomethacin

321- Pyelonephritis Treatment:

a-Amoxicillin+clavulinic b- Cephalexin
c-Nitofurantoin
322- Therapeutic drug monitoring (TDM) aim is to:
individualize pharmacokinetic parameter

323- the best drug dlivery in the infant:

a- Evohaler b- Turbuhaler
c- Inhaler d-Neutralizer

324- case diabetes + keto acidosis + BP (90/60)+ Na K

slight high + HCO3 low initiate with :
a-Insuin b- Saline 0. 9%
c-HCO3

325- fentanyl patch :

a-Expose to heat to increse absorption
b- Put in refrigerator
c-Avoid the increase of body core temp
d- Rotate to avoid tolerance

326- 1% pilocarpine ....how many microgram in 1drop:

ITEM Mean or equal =
1% 1 gm -----100 ml
1 ml 16 drops
1 drop 0.0625 ml
1 gram 1000000 µg

1 ml ---------- 16 drops
y ml ---------- 1 drop
y = 1/16 = 0.0625 ml

1 gm ---------- 100 ml
x gm ---------- 0.0625 ml

x = 0.0625/100 = 0.000625 gm
= 625 µg

: ‫مالحظة‬
‫ نقطه‬16 = ‫ملي‬1 ‫ ولذلك احنا حليناها علي ان‬.. ‫ملي بيساوي كام نقطه‬1 ‫في المسأله مكنش جايب‬
327- maximun infusion rate of vancomycin:
a- 1 ml/min b- 2 ml/min
c- 3 ml/min d- 4 ml/min

328- Mechanism of Action of Cromolyn sodium:

Mast cell stabilizer; inhibits release of histamine, leukotrienes, and

slow-reacting substance of anaphylaxis from mast cell by inhibiting
degranulation following exposure to reactive antigens

329- Head lice ttt :

-Permethrin -Lindan -Malathion -Ivermectin
-Piperonyl butoxid -Itraconazol -Terbinafin -Benzyl alcohol lotion
330- what kind of error for dose more or less than
prescribed:
Improper dose Error

331- pt after injection amoxicillin suffer from dyspnea and

Hypotension & NOW need ABX for URTI :
a-ampicillin b- cefaclor c- erythromycin

332- smoking effect on olanzapine:

a- increase metabolism b- Decrease metabolism
c- No effect between them

333- voriconazole dose should be adjusted in :

a- liver cirrhosis b- renal failure
334- Patient treated for long time with alpha blocker as
ttt for bladder. Dr. Decided to give phosphodiesterase
inhibitor:
a- sildenafil with tamsulosin
b- tadalfil after 4 hrs from tamsulosin
c- tadalafil before tamsulosin 4 hrs
d- take tadalafil with tamsulosin

335- patient suffer greenish yellow sputum . Dr exclude

antibacterial and say it is viral . Ask patient to take
ingredient which can added to cough admixture.:
a- dextromethorphan b- guaifenesin

336- mild dry cough :

a- dextromethorphan b- guaifenesin

337- epoetin for ttt anemia caused by kidney disease. Iron

or hemoglobin conc should be :
a- 11 mg/dl b- 13 mg/dl c-16 mg/dl

338- mother went to pharmacist her baby 1 month old

suffer from mild fever:
a- paracetamol nasal metered dose 15 mg / kg
b- ibuprofen syrup dose 12 mg /kg
339- most common cause for Pediatric dose error than
adult:
a- most medication is weight dependant
b- most medication is liquid
c- greater surface area

340- fluxetine wash out:

a- 2 weeks b- 3 weeks c- 4 weeks

341- Who sign the form send to sFDA TO investigate in

drug :
a- physician/consultant b- cheif pharmacist
c- head nurse d- investigator

342- - pt hypertension ll should take:

a- losartan/ hydrochlorothiazide b- Amodarone/ triamterene

343- pt suffered before from acute migraine attack

combined with aura . Now suffering from migraine should
take:
a- paracetamol 1000 four times daily
b- ibuprofen 400 four times daily

344- pt with melena. , bloody stool endoscopy

erthomatous mucosa. Should take :
a- bevacizumab b- pabizumab
c- cyclsporin d- sulfasalazin
345- dr prescribed for pt with open angle glucoma eye
drops one drop / day and told him to administer:
a- at night b- at morning c- any time

346- furosemide Iv (i think 120 mg) should take:

a- 10 min b- 20 min c- 30 min

347- normal water used for:

a- iphthalmic b- parental c- external preparation

348- to say suspension is good:

a- moderate shaking for reconstitution
b- bulk at the bottom

349- drug is waiting to be in in folmulary of hospital is

called: non formulary

350- lactating woman took pseudoephdrine what effect

on baby:

Mothers reported irritability was reported in 20% of infants exposed

to pseudoephedrine.

351- reconsituation antibiotic or refregirated should used

within:
a- 7 days b- 14 days c-30 days
352- drug is waiting approval from sfda to be
commercial :
a- non formulary drug b- unregistered drug

353- nurse received extra vial in the bag what should do:
a- keep until next dose b- return to pharmacy

354- pateient receive morphine 60 mg every 12 hr

Dr will change to fentanyl. What will be dose:
a-1.2 mg/d b- 5 mg/d c-12 mg/

355- Case pt take ACEI but he become suffer from cough:

Stop ACEI and shift to ARBs

356- 12 years baby weight : 30 kg & length 120 cm should

receive medicine 5 mg/m2
What is the total dose:
357- pt with renal failure shouldn't take mg sulphate:

a- it decrease excretion of Mg
b- it increase excretion of Mg
c-it decreases absorption of mg from intestine

358- dr want to know about interactions between garlic and

drug( I don't remember) he should read

How do I check for drug interactions?

Review the Medication Guide, prescription information, warning labels, and Drug
Facts Label with each new prescription or OTC product. Labeling may change as new
information is learned about medications, so it’s important to review the
information frequently.

359- which drug is dangerous & CI in third trimester:

a- methotrexate b- lithium

Information:
1- methotrexate is category X and it mean never use with mother and its danger to her live .

2- Lithium is category D and it mean that it is danger to fetal

*Risks of Using Lithium in Pregnancy
First trimester – there is a small risk of congenital problems, including serious heart malformation.

Second trimester – there continues to be a risk of congenital problems, but not to the same degree
360- Sulfasalazine:
antiinflammatory and immunosuppressive properties of 5-ASA, suggesting a
multifactorial basis of therapeutic action. These properties include:

• Inhibition of prostaglandin and leukotriene synthesis

• Free radical scavenging

• Immunosuppressive activity

• Impairment of white cell adhesion and function

• Inhibition of cytokine synthesis

• Activation of the peroxisome proliferator-activated receptor-gamma (PPAR-

]]] gamma)

361- diphenoxylate works on:

a- opioid receptors agonist
b- opioid receptors antagonist

362- drug for nausea & vomiting in cancer pt:

Granisteron

Drugs That May Be Prescribed by Your Doctor:

When suffering from nausea caused by chemotherapy treatments, your doctor will
prescribe anti-nausea medications to prevent or relieve nausea.
Likewise, your doctor may not prescribe any anti-nausea drugs because not all
chemotherapy cause nausea and vomiting. However, if the chemotherapy is likely to
cause nausea and vomiting, your doctor may prescribe one or more of the following
common anti-nausea medications:

• Aprepitant (Emend®)
• Dolasetron (Anzemet®)
363- Dose related SEs of 200 mM/L phynetoin:
a-Coma b- Nystagmus
c- Ataxia d- Decrease mental status

364- pt suffered before from migraine attack wz aura

He need drug as for prophylaxis:
a- Aspirin 75 Twice daily
b- Propranolol 20 mg twice
c- Topiramate 25 mg twice
365- Drug cause pulmonary toxicity:
a- Desopyramide b- Amiodarone c- Lithium

366- pt on clozapine ttt , what shuld be checked during ttt

RBCs:
a- Platelets b- Neutrophils

367- pt suffer from psychosis and he take certain

medication ..Then he develop involuntry movements in
face and mouth two weaks after …What is the drug he take
?:
a- Closapine b- Haloperidole

368- pt with HTN and developed ankle edema , also have

proteinurea .. Dr can prescribe ?:
a-Irbesartan b-Amlodipine
c- Hydrochlorothiazide

369- Drug used in multiple sclerosis (MS):

a-Inflizmab b- Abatacept c-Fingolimd

370- 44 years pt with BP 160/95 The best approbriate

Enalapril with B blocker:
a-Losartan and thiazide b- Amlodipine and ARBs
371- Most occurring error in prescription
a-Wrong drug order b- Omission order
c-Misinterpretion durg order

372- Dr prescribe chlorpheniramine for a driver but the

pharmacist discover a problem:
a-The error occur and drug will reach the the pt
b- Th error occur and drug won't reach the pt
c-There is no error

373- what is the effect of smoking on clozapine drug:

smoking will decrease the level or effect of clozapine by affecting

hepatic enzyme CYP1A2 metabolism. Use Caution/Monitor.

374- drug to cause serotonin syndrome while ttt the

symptoms accompanied by chemotherapy ttt:
a-Flouxetine b- Granisetron

375- Pt with BPH and classified as first degree Drug to

use:
a-Finasteride b- Tamsulosin
c-The two

376- Used in anxiety without produce withdrawal symptoms

:
a-Flouxetine b- Buspirone
c-Phenbarbital
377- pt with Inflammatory bowel disease (IBD) the initial
ttt:
a-Abatacept b- pertulsmab c-Sulfasalazin

378- pt suffer from aspergillus what is the ttt :

Voriconazole
Amphterocin_B
Cuspofungin

379- new born with fever , dyspnea and jaundice

He can take :
a-Ampicillin and gentamicin
b- Ceftazidime and gentamicin
c-Ampicillin and ceftriaxone

380- babie infected with ( i think with tuberculosis):

a-family should take rifampicin
b- should take rifampicin within
c-rifampicin has no role in protection

381- If maximum moisturization required use :

a-Cream b- Lotion
c-Ointment

Important Notes
 ** List of High-Alert Medications **

** Helicobacter pylori Infection Treatment **

First line :
 1- Proton pump inhibitor (PPI) (eg, omeprazole 20 mg BID, lansoprazole 30
mg BID, esomeprazole 40 mg QD, pantoprazole 40 mg QD, rabeprazole 20
mg BID) plus
2- Clarithromycin 500 mg BID (first-line) or metronidazole 500 mg BID [3]
(when clarithromycin resistance is increasing) plus
3- Amoxicillin 1000 mg BID or metronidazole.

Second Line :

** 1st & 2nd gen antihistamines **

**list of weak electrolytes**

** Pregnancy Categories**