Peter Parker lives with his Aunt May and Uncle Ben.
On a school trip, he visits a genetics
laboratory with his friend Harry Osborn and Mary Jane Watson. There, Peter is bitten by a "super
spider." after arriving home, he becomes unconscious. After Harry's father, s Norman Osborn,
owner of Oscorp, is trying to secure an important military contract. He experiments on himself
with a performance-enhancing chemical. After absorbing the chemical, he goes insane and kills his
assistant.
The next morning, Peter finds that his body has transform into a more muscular physique. At
school, he finds that his hands can produce webs, and his quick reflexes let him avoid during a
confrontation with Flash Thompson. Peter discovers he has developed superhuman speed,
strength, the ability to stick to surfaces, and an ability to sense danger.
Brushing off Ben's advice, Peter thinks of impressing Mary Jane with a car. He enters an
underground fighting and wins his first match, but the promoter cheats him out of his money.
When a thief suddenly raids the promoter's office, Peter allows him to escape. Moments later, he
discovers that Ben was robed, and killed. Peter pursues and confronts the robber, only to realize it
was the thief he let escape. After Peter disarms him, the robber flees and dies in the process. Then
Norman interrupts a military experiment by Oscorp's corporate rival and kills several scientists and
the military's General Slocum. Upon graduating, Peter begins using his abilities to fight injustice.
Norman, upon teach Oscorp's board members plan to force him out and sell the company,
assassinates them at the World Unity Fair. Jameson quickly dubs the mysterious killer the Green
Goblin. Norman offers Peter a place at his side, but Peter refuses. They fight, and Peter is
wounded. At Thanksgiving dinner, May invites Mary Jane, Harry, and Norman. During the dinner,
Norman sees the wound and realizes Peter's identity. Shortly after he leaves, Norman attacks, and
hospitalizes May.
Mary Jane admits she is crazy for Spider-Man, who has rescued her in many occasions, and asks
Peter whether Spider-Man ever asked about her. Harry, who is dating Mary Jane, arrives and
presumes she has feelings for Peter after seeing them hold hands. Devastated, Harry tells his
father that Peter loves Mary Jane, unintentionally revealing Spider-Man's biggest weakness.
Norman holds Mary Jane and a Roosevelt Island Tram car full of children hostage alongside the
Queensboro Bridge. He forces Peter to choose whom he wants to save and drops Mary Jane and
the children. Peter saves both Mary Jane and the car, while Norman is pelted by civilians who side
with Spider-Man.
Norman reveals himself to Peter, who stops attacking. He begs for forgiveness, but at the same
time controls his glider to impale him Sensing the attack, Peter dodges, and the glider impales
Norman. As he dies, Norman begs Peter not to tell Harry of Norman's identity. Peter takes
Norman's body back to his house. Harry arrives to find a costumed Peter standing over his father's
body. He seizes a gun, intent on shooting Peter, but Peter escapes and hides Norman's equipment.
At Norman's funeral, Harry swears vengeance toward Spider-Man, whom he deems responsible
for his father's death.
