Kylah Grace D Giganto BSN2C

Name of drug Dosage, Mechanism of Action Indication Contraindication Adverse Reaction Nursing Responsibility
Route,
Frequency

Generic Name: Dosage: − Penicillin-binding − Co-Amoxiclav is for − Allergy to Gastrointestinal effects: − Assessing the patient's
Amoxicillin- 625mg/tab protein 1 and other short-term treatment of penicillins: Co- These are the most medical history:
clavulanate 2 tablets high-molecular-weight bacterial infections at amoxiclav is a common side effects of Before administering
penicillin binding the following sites: member of the co-amoxiclav and can co-amoxiclav, it is
Brand Name: Frequency: proteins are Upper respiratory tract penicillin class of include diarrhea, nausea, important to review
Augmentin 2x a Day competitively infections [including antibiotics and vomiting, and abdominal the patient's medical
BID inhibited by eyes, ears, nose should not be used pain. history and identify
Classification: amoxicillin. Penicillin (EENT)] e.g., recurrent in patients who any contraindications,
Antibiotic Timing: binding proteins are in tonsillitis, sinusitis, have a known Hypersensitivity allergies, or potential
8AM – 8PM charge of the otitis media. allergy to reactions: Co-amoxiclav drug interactions.
glycosyltransferase − Lower respiratory tract penicillins. Allergic can cause allergic − Administering the
Route: and transpeptidase infections e.g., acute reactions can range reactions in some people, medication as
Oral reactions that result in exacerbation of chronic from mild rashes to which can range from prescribed: Co-
the cross-linking of D- bronchitis, lobar and severe anaphylaxis, mild skin rashes to severe amoxiclav is typically
alanine and D-aspartic bronchopneumonia. which is a life- anaphylaxis. administered orally in
acid in bacterial cell − Skin and soft tissue threatening allergic the form of tablets or
walls. Without infections e.g., boils, reaction. capsules, and should
penicillin binding abscesses, cellulitis, − Severe liver Liver toxicity: Co- be given according to
proteins, bacteria wound infections. disease: Co- amoxiclav can cause liver the prescribed dosage
upregulate autolytic Bone and joint amoxiclav can damage in some people, and frequency. The
enzymes and are infections e.g., cause liver damage, particularly in those with medication should be
unable to construct osteomyelitis. and should be used pre-existing liver disease. taken with a full glass
and repair the cell − Other infections e.g., with caution in of water to ensure
wall, leading to dental infections, septic patients with pre- Blood disorders: Co- adequate absorption.
bacterial action. abortion, puerperal existing liver amoxiclav can affect the − Encouraging fluid
sepsis, intra-abdominal disease. It is production of blood cells intake: Co-amoxiclav
sepsis. Also septicemia, generally and may cause anemia, can cause dehydration
peritonitis and contraindicated in thrombocytopenia, or and electrolyte
postsurgical infections. patients with severe leukopenia. imbalances, so it is
liver disease, as it important to
encourage the patient
− Co-Amoxiclav is also can worsen their Neurological effects: to drink plenty of
indicated for condition. Rarely, co-amoxiclav can fluids, particularly
prophylaxis against − Kidney disease: cause neurological side water.
infection which may be Co-amoxiclav is effects such as dizziness, − Educating the patient
associated with major excreted by the headaches, or seizures. about potential side
surgical procedures kidneys, so it effects: Before
e.g., gastrointestinal, should be used with Candidiasis: Co- administering co-
pelvic, head and neck, caution in patients amoxiclav can disrupt the amoxiclav, it is
cardiac, renal, joint with kidney balance of bacteria and important to educate
replacement and biliary disease. Dose yeast in the body, leading the patient about
tract. adjustments may be to overgrowth of Candida potential side effects,
necessary in these albicans, a type of yeast such as
patients. that can cause infections. gastrointestinal upset,
− Infectious rash, or difficulty
mononucleosis: breathing. The patient
Co-amoxiclav is Renal effects: Co- should be instructed to
not recommended amoxiclav can cause notify the physician if
in patients with kidney damage in some they experience any
infectious people, particularly those adverse reactions.
mononucleosis, as with pre-existing kidney − Monitoring renal and
it can cause a rash. disease. liver function: Co-
− Pregnancy and amoxiclav can affect
breastfeeding: Co- Superinfection: Co- renal and liver
amoxiclav is amoxiclav can cause function, so it is
generally secondary infections in important to monitor
considered safe for some people, particularly these parameters in
use during if it is used for a patients with pre-
pregnancy and prolonged period of time. existing renal or liver
breastfeeding, but disease. Blood tests
its use should be may be necessary to
carefully assess kidney and liver
considered by a function.
doctor, particularly
in the first trimester
of pregnancy.
− Concomitant use
of certain
medications: Co-
amoxiclav may
interact with other
medications,
particularly those
that affect liver
function or blood
clotting. It should
not be used in
combination with
certain
medications, such
as methotrexate,
that can increase
the risk of side
effects.