See Brilliant Results

without all the reviews.

* In Development
Product not available in the U.S.
 First Pass Efficiency.™
Getting it right the first time.
GOALS: More reportable WBC and WBC • Reduces reflex testing due to interference
differential results on the first run, even from microcytic RBCs, RBC fragments,
when abnormal cells and interfering WBC fragments and non-platelet particles.
substances are present:
Three dimensional optical RBC count.
• MAPSS™ (Multi-Angle Polarized
Scatter Separation) technology provides • Improved RBC count accuracy.
laser-accurate optical readings for WBCs • Clinically useful RBC parameters.
with differential.
Flexible, easy-to-use software.
• Accurate identification using 4-angle
scatter measurements. • Features customizable views.
• Use of multiple scatterplot analysis • Easily performs non-routine tasks.
for identification of abnormal cells Only three reagents for complete CBC
and interfering substances. with 5-part WBC differential analysis.
First pass optical platelets. • WBC lyse
Right the first time. • HGB lyse
• The CELL-DYN Ruby 2-angle optical
™
• Diluent/sheath
platelet count accurately enumerates
and sizes to help ensure first pass
reportable results.

A shining example of advanced technology.

* In Development
Product not available in the U.S.
 Abbott Hematology.
The First with First Pass Efficiency.™
Highly discriminate, sequential MAPSS Laser Technology.
separation using MAPSS™ technology. A higher level of interrogation.
• Analysis performed on up to 10,000 cells from
90º D Granularity a single dilution, using a single reagent.
90º Lobularity • Captures up to 40,000 data points.
10º Complexity
MAPSS results are displayed in elegant, multiple,
0º Size color-coded scatterplots.
• Discriminates between neutrophils, eosinophils,
Four degrees of basophils, monocytes and lymphocytes.
separation in a flash
• Identifies and classifies immature cells
and interfering substances.

1. Mononuclear 3. Basophil
Polymorph Lymphocyte
Separation Monocyte
Separation

2. Neutrophil 4. Display of Five

Eosinophil Normal Cell
Separation Populations

How MAPSS™ differentiates and classifies.

Size Complexity Lobularity Granularity Classification
Cell Oo 10o 90o 90o Depolarized 1st 2nd 3rd 4th
1 165 162 116 32 POLY NEUT — —
2 60 64 15 6 MONO — — LYMPH
3 140 79 21 99 MONO — — MONO
4 148 182 104 118 POLY EOS — —
5 90 110 28 8 MONO — BASO —

MAPSS ™
Three-dimensional, Optical Red Blood Cell Analysis.

Improves the accuracy of red cell measurements, • Retics analyzed via 0º, 10º,
including retics, with 3-D analysis. and 90º scatter.
• Comprehensive cell-by-cell measurements • Retic assay based upon
with readings taken at 0º, 10º, and 90º for NCCLS/ICSH methods.
exquisite accuracy.

RED CELLS
90O

0O

10O

Red cell size and

size distributions
are displayed using
a histogram of
the 0o scatter.
Two-dimensional, Optical Platelet Analysis.

More reportable platelet counts across a • More reportable results are obtained:
wide variety of abnormal conditions. —without reflexing or extra reagents,
• Two-angle analysis separates the platelet —in presence of giant or clumped
and RBC populations. platelets using 2-D separation,
• Reduced interference from microcytic —on thrombocytopenic samples, and
RBCs, schistocytes, RBC fragments, —without dilution, on samples
or non-platelet particles. with thrombocytosis.

P L AT E L E T S

0O

10O

First Pass Optical Platelet Count:

Platelets and RBCs are accurately sized
and counted by multidimensional laser
light scatter. Whole blood is diluted
into a proprietary reagent system that
optimizes the separation of Platelets and
RBCs reducing interference by microcytic
red cells and non-platelet particles.
 Four-dimensional, WBC Analysis.

White cells are counted and studied so • MAPSS technology can detect potential
that results can be reported on the first interference from lysis-resistant red cells.
run, even when abnormal cells and These samples can be re-run in the
interfering substances are present. lysis-resistant mode without microscopic
• Reduced manual reviews due to review (See Figures 1 & 2).
interference from NRBCs, clumped
platelets and debris.

WHITE CELLS • 1
Neutrophils and
eosinophils are
separated from
lymphocytes,
monocytes and
basophils by
differences in
their complexity
and lobularity.

•
•

Figure 1:
The occurrence of a
significant population
of cells occurring 2 3 4
below the dynamic Neutrophils are Basophils are separated The net result
WOC threshold can separated from using both size (0 degrees) is the excellent
suggest the presence eosinophils by virtue and complexity (10 degrees) discrimination
of lysis-resistant RBCs. of their different readings, allowing lymphocytes of 5 normal cell
characteristics in and monocytes to be separated populations.
scattering polarized by size (0 degrees) information.
(90º) and depolarized
Figure 2: (90º D) light.
In cases where lysis-
resistant RBCs occur,
(typically in neonates
and patients with
hemoglobinopathies,
thalassaemia or liver
disease) the sample is
re-run in the resistant
RBC mode. * In Development
Product not available in the U.S.
Multi-faceted software offers touch-screen
convenience and maximum flexibility.
Easy for everyone.
• Screens are straightforward, intuitive,
and easy to navigate.
• The software offers customizable views
(Based on SQL Data Base).
• Handy tool tips help optimize
operator’s experience.
• Automatic monitoring of reagent status.

Even non-routine tasks are easy

to perform and user-friendly:
• Calibration functions
• Help menus
• Help videos

Configured for Security.

User sign-in is password-protected with
multiple security levels.

QC Files.
Users can store up to 500 quality
control files.

Run View-Chartable Information Run View-Lab Information Only Data Log

WBC, RBC, and Plt information for Patient In Lab View you can see additional parameters for Patient and Quality Control information is
and Quality Control results are clearly displayed internal lab use. For the differential they include stored for up to 10,000 results. Information is
using color-coding. Flagged specimens are easily BAND, IG, BLST (Blast), VARL (Variant Lymph) quickly and easily retrieved with user-friendly
identified. Operators may select up to 9 different absolute and percentage values. Additional search menus.
scatter gram views at the click of a button. hematology parameters are the PCT and PDW.

QCID Maintenance
In QC VIEW you can toggle from Levey-Jennings® All maintenance information is easily monitored
Plots to Data Summaries through the lower left on a single screen. An on-line Operator's Manual
function key labeled QCID DATA and QCID L-J Plots. and Help Videos are always available to assist in
performing maintenance functions.
Simply. Brilliant. Technology.
PRODUCT GOALS

THROUGHPUT CBC + Differential up to 76 per hour

SAMPLE VOLUME Open Mode 150 μL, Sample Loader 250 μL
REAGENTS Only 4 reagents including reticulocytes
TECHNOLOGY
WBC AND DIFFERENTIAL 4 angle optical MAPSS™ Multiple Scatterplot Analysis
PLATELETS Dual angle optical analysis, no extra reagent, no reflex testing requirement
RETICULOCYTES New Methylene Blue NCCLS/ICSH methods, supravital staining technique

Data Management Reportable Parameter Goals

• Microsoft Windows® based
Operating System WHITE CELLS RED CELLS PLATELETS RETICULOCYTES
• Touch Screen Monitor
• Full on-board QC NOC WOC NEU RBC HGB PLT RETIC#
- Summary statistics and %N LYM %L HCT MCV MPV RETIC%
Levey-Jennings® plots MONO %M EOS MCH MCHC
- Moving averages %E BASO %B RDW Retic
(including WBC differential) %R
- Westgard rules
• 10,000 results stored with graphics
• Work list capability
• Programmable patient and report limits Electrical Requirements
• Complete patient demographics
• Bar code reading: Code 39, Codabar, MAXIMUM MAXIMUM POWER
Code 128, Interleaved 2 of 5, ISBT MODULE VOLTAGE FREQUENCY CURRENT CONSUMPTION
• Auto-calibration on-line guide
• On-board diagnostics and Help Videos Analyzer 100-240 VAC 50/60 ± 3Hz 0.5-2.2 amps 550 watts
Display 100-240 VAC 50/60 ± 3Hz 0.7 amps 50 watts
Operating Environment
Temperature
• 15°C (59°F) to 30°C (86°F)

Humidity
•<
_ 80% relative humidity, System Measurements
non-condensing Indoor Use
Standards & MODULE HEIGHT WIDTH DEPTH WEIGHT
Safety Compliance
UL Analyzer 49.9 cm 86.4 cm 76.8 cm 105.2 kg
CSA (19.25 in.) (34.0 in.) (30.25 in.) (232.0 lbs.)
IEC 1010
CE Mark Printer Refer to the printer manufacturer's specifications
Ordering Information
08H67-01 CELL-DYN Ruby™ Analyzer
09H04-01 Accessory Kit
05H00-01 17” Touch Screen Monitor
08H14-01 Membrane Keyboard

www.abbottdiagnostics.com
1.800.323.9100
* In Development © 2006 Abbott Laboratories Printed in the USA
Product not available in the U.S. Windows is a registered trademark of Microsoft Corporation.

Abbott GmbH & Co. KG

Abbott Diagnostics Europe
Max-Planck-Ring 2
65205 Wiesbaden
Tel. (+49) 61 22 58 0
Fax (+49) 61 22 58 12 44
www.abbottdiagnostics.com

AH2205/uk CELL-DYN® Ruby 05/06/1