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Drug Study 2

Gentamicin is an aminoglycoside antibiotic with the brand name Gentacare. It works by binding to bacterial ribosomes and disrupting protein synthesis. The recommended dosage is 12 mg administered intravenously every 12 hours to treat aerobic bacterial infections. Nursing responsibilities include verifying orders, observing safe administration practices, monitoring for allergic reactions, and reporting any signs of muscle weakness or hypersensitivity.
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0% found this document useful (0 votes)
34 views2 pages

Drug Study 2

Gentamicin is an aminoglycoside antibiotic with the brand name Gentacare. It works by binding to bacterial ribosomes and disrupting protein synthesis. The recommended dosage is 12 mg administered intravenously every 12 hours to treat aerobic bacterial infections. Nursing responsibilities include verifying orders, observing safe administration practices, monitoring for allergic reactions, and reporting any signs of muscle weakness or hypersensitivity.
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DRUG STUDY

Generic Name: Gentamicin

Brand Name: Gentacare

Classification:

Therapeutic: Aminoglycoside antibiotic

Dosage, Frequency, and Route: 12 mg IV q 12 hrs

Mechanism of Action: Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal
subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell
membrane defective.

Desired Effect: To treat infection by stopping the growth of aerobic bacteria.

Nursing Responsibilities and Rationale:

Nursing Responsibilities Rationale

Safe and effective drug administration

1. Verify the doctor’s order ● To ensure and verify the right


procedure to the right patient.

2. Observe the 13 Rs of medication ● To prevent medication errors and


administration. ensure the patient's safety.

3. Perform hand hygiene before and ● To reduce the transmission of


after administration. microorganisms.

4. Assess for any allergies to any ● To prevent adverse reactions.


aminoglycosides; renal or hepatic
disease; preexisting hearing loss;
active infection with herpes, vaccinia,
varicella, fungal infections,
myobacterial infections (ophthalmic
preparations); myasthenia gravis;
parkinsonism; infant botulism;
lactation, pregnancy.

5. Administer the medication slowly. ● To prevent vein injury.

6. Always wash hands thoroughly and ● To prevent the spread of infection.


disinfect equipment (whirlpools,
electrotherapeutic devices,
treatment tables, and so forth).

7. Report any muscle weakness or ● To provide emergent interventions


paralysis that occurs following when adverse reactions occur.
injection of high doses to the
physician.

8. Monitor signs of hypersensitivity ● To provide emergent interventions


reactions, including pulmonary when adverse reactions occur.
symptoms (tightness in the throat
and chest, wheezing, cough dyspnea)
or skin reactions (rash, pruritus,
urticaria).

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