Kingdom of Fungi                                                 One yeast cell produce up to 24 daughter cell
 Eukaryotic       (have     membrane-bound                    by budding.
     nucleus)                                             Pseudohyphae – short chain of cells that fall to
    Obtain food from other organism                      detach from buds (e.g. Candida albicans)
    Possess cell wall (CHITIN)
    Not photosynthetic                                   Dimorphic Fungi
    Fungi can be unicellular (yeast) and                    Pathogenic      fungal    species          exhibit
     multicellular (mold)                                      Dimorphism.
Composed of:                                                 Two forms of growth
                                                             Can grow either as a mold or yeast
mold – multicellular, have hyphae; reproduce by
                                                             Temperature dependent.
sexual and asexual spores.
                                                          Life Cycle
Yeast – unicellular; reproduce asexually by
budding; some produce sexual spores.                           Reproduction of fungi can be either asexual or
                                                                sexual.
mushroom – multicellular; resembles plants.
                                                          Asexual spores – formed by the hyphae of one
Importance of Fungi
                                                          organism.
    Important     in the     food    chain         as
                                                               When spores germinate, it become organisms
      decomposers.
                                                                  that are genetically identical to the parent.
mycorrhizae – a symbiosis pf plants that help
                                                          Sexual spores – result from the fusion of nuclei
roots absorb minerals and water from the soil.
                                                          from two opposite mating strains of the same species
     Beneficial as a source of food and to
                                                          of fungi.
        produce foods and drugs.
     More than 100,000 species, only about 200 are       Asexual Spore Formation
        pathogenic.                                           Two types of asexual spores produced by
Characteristics of Fungi                                       fungi.
Fruiting Body                                                 1. Conidiospore/Conidium
                                                               A unicellular or multicellular spore that is not
    Reproductive structure that creates spores.
                                                                 enclosed in a sac.
Hyphae (sing; hypha)
                                                          Arthroconidia – conidia formed by hyphae
   Long thin filaments of cells that make up the
                                                          fragmentation of septate hyphae into single, slightly
     fungus body.
                                                          thickened cells (Coccidia immitis).
   Hyphae contain cross wall called septa,
     divided into uninucleate cell-like units (septate    Blastoconidia – consists of buds coming off the
     hyphae).                                             parent cell.
      Coenocytic hyphae – no septa, with long            Clamydoconidium – thick-walled spore formed
       continuous cells with many nuclei.                 by rounding and enlargement within a hyphal segment
Vegetative vs. Aerial Hyphae                              (Candida albicans).
                                                              2. Sporangiospore
Vegetative Hyphae – the portion of hyphae that
                                                               Formed within a sporangium, at the end of
obtains nutrients.
                                                                 an aerial hyphae called sporangiophore.
Aerial     Hyphae     –   portion   concerned      with        Produce by Rhizopus.
reproduction.                                             Sexual Spores
Yeast
                                                          Plasmogamy – a haploid nucleus of a donor cells
    Non-filamentous, unicellular fungi that are
                                                          penetrates the cytoplasm of a recipient cell.
      typically spherical or oval.
    Widely distributed in nature.                        Karyogamy – the (+) and (-) nuclei fuse to form a
    Frequently found as white powdery coating on         diploid nucleus.
      fruits and leaves.                                  meiosis – the diploid nucleus gives rise to haploid
    Capable of facultative anaerobic growth.             nuclei (sexual spores).
    Can perform aerobic           respiration   to
                                                          Sexual Spores
      metabolize carbohydrates.
Reproduction in Yeast by Budding                          Zygospores – sturdy diploid spores formed when
   1. Yeast cell                                          hyphae of two opposite strains (called the plus and
   2. Developing bud                                      minus strains) fuse and create a diploid zygote that
   3. New bud                                             swells and becomes covered by strong, spiny walls.
   4. Chain of buds
Ascospores – haploid spores, created inside a special              -   Opportunistic pathogen – generally
fungal sac.                                                            harmless in its normal habitat but can be
Basidiospores – haploid sexual spores formed on                        pathogenic in a host that is debilitated or
the outside of a club-shaped cell called a basidium.                   traumatized, under treatment with high-
                                                                       broad spectrum antibiotics, immune
Classification                                                         suppressed by drugs or has a lung disease.
   1. Zygomycetes: bread and terrestrial molds.                    -   Caused by normal microbiota or fungi that
      Reproductive spores are external and                             are not usually pathogenic (E.g.,
      uncovered. Sexual spores are zygospores, and                     Pneumocystis,              Stachybotrys,
      asexual spores are sporangiospores.                              Mucormycosis,               Aspergillosis,
                                                                       Candidiasis).
   2. Ascomycetes: yeasts and molds. Sexual
                                                                           Survey of Protist: Algae
      spores, called ascospores, are produced in a
      saclike structure called an ascus. Conidia are               Algae
      sexual spores produced on a conidiophore.                   Are eukaryotic protist, usually unicellular or
   3. Basidiomycetes: fleshy fungi, toadstools,                    colonial, that photosynthesize with chlorophyl.
      mushrooms, puffballs, and bracket fungi.                     They lack vascular systems for transport and
      Reproductive spores, basidiospores, are                      have simple reproductive structures.
      separate from specialized stalks called                     Chloroplasts – chlorophyll (green pigment).
      basidia.                                                     Yellow, Red, Brown Coloration.
   4. Deuteromycetes: also called Fungi                           Plankton – large floating, community of
      Imperfecti because no sexual reproductive                    microscopic organisms.
      phase has been observed.                                    Aquatic Food, webs. Oxygen content of the
Dead man’s Finger                                                  atmosphere through photosynthesis.
   A saprobic fungus. It is a common                       Vegetative Structure
     inhabitant of forest and woodland areas,                   The body of an algae is called a thallus.
     usually growing from the bases of rotting or               Thalli in large multicellular algae is consists
     injured tree stumps and decaying wood.                       of:
               Fungal Diseases
                                                                   - Holdfast – anchor the algae to a rock.
mycosis                                                           Some algae are buoyant by floating, gas- failed
      Systematic mycoses – fungal infections                      bladder called pneumatocyst.
       deep within the body.                                Selected Phyla of Algae
       - Usually caused by fungi that live in the                 Brown Algae, or kelp – are macroscopic,
           soil.                                                   some reach 50 km.
       - Primary involve the respiratory system.
                                                                  Found in coastal waters.
       - Histoplasmosis                         and
           Coccidioidomycosis.                                    Algin – a polysaccharide extracted from cell
      Subcutaneous           mycoses    – fungal                  walls used as stabilizer and emulsifier.
                                                                  Used in ice cream and cake decorations and
       infections beneath the skin.
                                                                   variety of nonfood goods including rubber
       - Caused by saprophytic fungi that
                                                                   wires and hand lotion.
           lived in soil and vegetation.
       - Sporotrichosis – a subcutaneous                          Laminaria japonica – used to induce
           infection.                                              vaginal dilation before surgical entry into the
                                                                   uterus through the vagina.
      Cutaneous mycoses – fungi that infect
       only     epidermis,      hair,      and      nails   Green Algae – have cells walls, contain chlorophyll
       (Dermatophytes).                                     a and b.
       - Secretes an enzymes that degrade keratin,               Microscopic, although may either unicellular
           a protein found in hair, skin, and nails.                 or multicellular.
                                                                 An important food source for aquatic
      Superficial mycoses – fungi localized
                                                                     organisms.
       along hair shafts and superficial epidermal
       cells.                                               Diatoms – unicellular, or filamentous algae with cell
                                                            walls consist of pectin and silica.
                                                                 Store energy in form on oil.
                                                                 Domoic acid – neurological disease.
      Ingestion of mussels that fed on diatoms (also
       affects birds and sealions).                           Pseudopods – blunt, branches, or long and
                                                               pointed, depending on the species. Flowing
Dinoflageßates – a toxic marine algae.                         action results to amoeboid motion. Also acts as
    Causes Red tide (Alexandrium)                             feeding structures.
    Produce neurotoxins (saxitoxins) which kills
                                                              Flageßa – vary in number. Some, attached
      fish, marine mammals, and humans e.g.:
      parasitic shellfish poisoning (PSP).                     along the length of the cell by an extension of
                                                               the cytoplasm membrane called the undulating
      Ciguatera – a disease caused by                         membrane.
       Gambierdiscus toxicus passes up the food
                                                              Cilia (Ciliates) – distributed over the
       chain and concentrated in large fish.
                                                               surface.
      Seasonal changes in nutrient, light, and
       temperature cause fluctuations in algae           Life Cycle and Reproduction
       populations.                                           Asexual Reproduction – mitotic cell
Protozoa                                                       division. Multiple Fission.
    “first animals”                                          Sexual Reproduction – Conjugation (A
    65, 000 known species.                                    form of genetic exchange in which members of
    Harmless, free – living inhabitants of water              two different mating types fuse temporarily
      and soil.                                                and exchange nuclei.)
    Few parasites collectively responsible for
      hundred of millions of infections of humans             Trophozoite – motile feeding stage; the
      each year.                                               activated, growing or vegetative stage in the
                                                               life cycle of the specific parasite.
Protozoan Form and Function
                                                              Cyst – dormant, resting stage entered by the
    Single cells containing the major eukaryotic
      organelles except chloroplast.                           protozoa when the environment become
                                                               unfavorable for growth and feeding.
    Feeding, reproduction, locomotion
                                                           medicaßy Important Protozoa
      Cytoplasm – Ectoplasm (Outer layer –
       locomotion      feeding, and   protection),         1. Archaezoa – lack mitochondria.
       Endoplasm (Granular inner Region –                   Have a unique organelle called mitosome.
       Nucleus, mitochondria, food and contractile          Live as symbionts in the digestive tract of
       vacuoles).                                             animals.
      Lack a cell wall.
                                                              Typicaßy       spindle – shaped,          with
      Outer boundary – regulates movement of                  flagella projecting from the front end.
       food, wastes and secretions.                           E.g. Trichomonas, Giardia
Nutritional and Habitat Range                              2. miRospora
   Adapted to wide range of habitats.                      Lack mitochondria and microtubules.
      Predominant Habitats – fresh and                     Groups of unicellular intracellular parasites
       Marine Water, Soil, Plants, and animals.               closely related to fungi.
      Heterotrophic                                        Possess a unique organelle, the polar tubule or
      Require food in complex organic form.                  polar filament, which is coiled inside a spore.
      Free – living species graze on lice cells of         E.g.          Enterocytozzon           bieneusi,
       bacteria and algae, scavenge dead plant or             Encephalitozoon spp.
       animal debris.                                      3. Amoebozoa
      Oral Grooves – special feeding structure,            Move via pseudopodia, a lobe – like
       carry food particles into a passageway or              projections of the cytoplasm.
       gullet that packages the captured food into            Entamoeba – the only pathogenic amoeba
       vacuoles for digestion.                                 found in human intestine.
      Parasitic species – live on the fluids of their        Acanthamoeba – growing in water
       host, such as plasma and digestive juices, or           including tap water, can infect the cornea and
       actively feed on tissues.                               cause blindness.
   Pseudopods       (False Foot), Flageßa          or         Balamuthia – free living amoeba; also found
   Cilia.                                                      in water.
    Some        move by gliding or twisting
       movement      by not using  locomotor
       structures.
4. Apicomplexa
 Non – motile; obligate intracellular parasites.
 Characterized by the presence of complex of
   special organelles at the apexes of their cells.
 Have a complex life cycle.
 Plasmodium, Babesia microti, Toxoplasma
   gondii, Cryptosporidium
    Sporozoite – the infective stage.
5.   Euglenozoa
    Move by flagella
    Hemoflagellates
    Trypanosoma spp.
    Sleeping sickness (T. gambiense)
    Chagas’ disease (T. cruzi)