Virology MCQ
1- Which of the following statements defines "virus" correctly:
a) Infectious agent that infects humans only
b) Infectious particle that is composed solely of protein.
c) A very small infectious agent (20 –350nm) that is obligate
intracellular can infect man, animals, plants and bacteria.
d) Infectious agent that cannot be killed
2- Basic viral structure includes:
a) Cell wall
b) Flagella
c) Nucleic acid and capsid
d) Peptidoglycan
3- Viruses have variable symmetry, they may be:
a) Helical
b) Icosahedral
c) Complex
d) All of the above
4- Regarding viral nucleic acid which is correct:
a) Only DNA
b) Only RNA
c) Both DNA and RNA
d) Either DNA or RNA, never both
5- Virus replication occurs in the following sequence:
a) Penetration , release, assembly, protein synthesis, uncoating,
penetration
b) Attachment, penetration, uncoating, transcription and
replication, protein synthesis , assembly, release
c) Penetration, assembly, replication, transcription, release, protein
synthesis
d) Attachment, replication, uncoating, protein synthesis ,
transcription, assembly, release
6- Positive stranded RNA viruses have which of the following
characteristics?
a) Their genome RNA can be translated directly as mRNA
b) They have to transcribe their genome RNA to a mirror image copy
as a mRNA
c) Their RNA genome is segmented
d) Their RNA genome is circular
7- Virus classification depends on:
a) Nucleic acid properties
b) Size, shape, type of symmetry
c) Presence or absence of envelope
d) All of the above
8- Regarding enveloped viruses:
a) Escape by budding from the cell surface.
b) Released by lysis and death of the infected cell.
c) Are resistant to acid and typically cause infection via the oro-
faecal route
d) Taken up into endosomes when infect host cells
9- Atypical virus like agents include all of the following except:
a) Virion
b) Prion
c) Pseudovirion
d) Viroid
10- Possible outcomes of viral infections of host cells include:
a) Acute infection
b) Chronic infection
c) Latency
d) All of the above
11- Persistent viral infections include:
a) Chronic infections
b) Latent infections
c) ”SIow virus” infections
d) All of the above
12- Virus shows the following effects on infected cells:
a) Viral replication modifies host cell gene transcription with loss of
normal cellular homeostasis.
b) Cell cycle does not affected by viral infection
c) Expression host cell enzymes (e.g kinases) does not altered.
13- Immune system fights virus via
a) Cytotoxic T-lymphocytes
b) Antibodies
c) Cytokines
d) All of the above
14- The ability of a virus to cause human infection or disease is
determined by:
a) Transmission
b) Virulence
c) Host susceptibility
d) All of the above
15- Virus infections can be transmitted by
a) Respiratory route
b) Transfusion of blood
c) Sexual exposure
d) All of the above
1-C 2-C 3-D 4-D 5-B
6-A 7-D 8-A 9-A 10-D
11-D 12-A 13-D 14-D 15-D