Shilajit - A Wonder Drug of Ayurveda: An Overview: Review Article
Shilajit - A Wonder Drug of Ayurveda: An Overview: Review Article
Review Article
been used for thousands of years in Ayurvedic system of Allergic cough will diminish, can effectively applied for joint
medicine, extensively for a variety of diseases. It has been disorders, remove gastric intestinal track, in curing deep
in extensive use in the preparation of a number of fissers with cracks11.
medicines and their utility has been most dependable
Physical Properties
because of the presence of many biologically active
chemical constituents5-7. Shilajit samples from diverse regions of the earth have
similar physical properties and qualitative chemical
Mythological Background
composition but they vary vividly in percentage ratio of
In ancient literature, Lord Shiva narrated the process of components. Physical properties like solubility, pH etc is
origin of the drug as during summer season, the mountains one of the vital and mandatory tests for standardisation.
get heated up and as a result these mountains releases the Solubility in water demonstrates that nearly 30-50% of the
extract of the exudate of Dhatu called as Shilajit. Hindus weight of Shilajit passes into the supernatent liquid and the
believe and there are many who claim to have met Sadhus remains includes minerals and plant residues in quantities
and Yogis in the high altitude Himalaya ranges, who live depending on purity of Shilajit. Shilajit is sticky and
and meditate for hundred of years without even getting tencious material with a shiny and polished surface easily
old or sick. They are able to withstand harsh weather soluble in water, alcohol and acetone. The studies reveal
condition with virtually little or no warm clothes, still that only about 60% of the raw material is soluble in water.
remain young and active throughout by taking the Shilajit samples did not soften, at ambient temperatures
substances said to be Shilajit. Shilajit believed to be but remained hard and brittle so that it was difficult to cut
"Amrit" given by Lord Shiva to mankind for eternal youth off small pieces. The pH of 1% of aqueous solutions varied
and health. According to Charaka and Susruta, at the time in the Shilajit obtained from different countries, namely
of Samudra Manthan (churning ocean) by Gods and 6.2 for India (Kumoan), 7.5 for Nepal (Dolpa), 6.8 for
Demons due to friction, heat was generated and as a result Pakistan (Peshawar) and 8.2 for Russia (Tien-Shan). When
great amount of sweat was formed. The sweat mixed with Shilajit samples were subjected to thermal analysis,
nectar thought to be divine by the Gods. The divine drug simultaneous thermal analysis curves differed bwtween
was distributed in little quantities to the mountains, the various heating runs indicating that samples of Shilajit are
same thing melted due to sun rays and become Lac or Jatu not uniform but expressed a batch dependence. The
like and hence Shilajit (shila: mountain + jit: won) got the differences were prominent in intensity and signal from
name. Ayurveda thus believed the formation of Shilajit especially at higher temperature. In an oxidising
from mountains due to the intense sun heat 1,2,8. atmosphere only exothermal process occur except during
the dehydration range upto 150° C (about 7% water). This
Uses in Traditional Medicine
indicates that Shilajit predominantly consists of organic
Shilajit is most important drug for many diseases. It was matter and the total mass loss in air amounts to 67.6%. In
used as a drug in prehistoric periods. Shilajit acts an agent an inert atmosphere a completely different behavior is
which enhances the property of other drugs. According to observed. The physiochemical study reveals that the
Ayurveda, Shilajit arrests the process of ageing and Arjuna (Terminalia arjuna), purified sample of Shilajit
produces rejuvenation which are of two important aspects exhibited pH 5.10, loss on drying 8.04%, ash value 18.76%,
of an Ayurvedic rasayana. It is prescribed to treat fractures, acid insoluble ash 10.57% and water soluble ash value
osteoarthritis, spondolysis, chronic bronchitis, nervous 84.66%12-14.
disorders, epilepsy, anemia, angina, jaundice, menorrhagia
Purification
and eczema. It has also been ascribed as a potent
aphrodisiac property. It is useful for treating kidney stones, Shilajit being a natural exudation from rocks containing a
oedema, piles, internal antiseptic, adiposity, to reduce fat large amount of contaminants like rock pieces, heavy
and anorevia. Traditionally, Shilajit is consumed by people metal ions, vegetable compounds, reactive free radicals,
from the north of India and Nepal and children usually take toxins and soil particles etc, which cause illness. Hence it
it with milk in their breakfast. The Sherpa claim to have is necessary to purify the Shilajit before using it for
Shilajit as a part of their diet, they constitute a population therapeutic purpose. Shilajit is purified as per classical
of strong men with very high level of healthy longevity. The methods, in decoction, with Triphala (powder of three
traditional uses include its action in genitourinary medicinal plant fruits namely: Embelica officinalis,
disorders, enlarged spleen, epilepsy and hemorrhoids9, 10. Terminalia chebula, Terminalia belerica) and expressed
juice of Bhringraja (Eclipta alba) in an iron container
According to traditional Indian knowledge, Shilajit exerts
successively for one day each. It may also be purified with
action as a tonic, laxative, expectorants, anti-bilious,
by mixing Shilajit in water/cow milk15,16.
lithotriptic and antihypertensive when given internally and
it acts as antiseptic, analgesic, deo-obstruent and Chemical Constituents
germicide when applied externally. Shilajit is given
Shilajit from different regions contained a large variation
alongwith milk to treat diabetes. It is used for applications
of organic compounds that can be broadly grouped into
of tongue and cheeks as a paint, prepared by mixing Shilajit
humic acid (80-85%) of total organic mass and non-humic
in hot water. It is also instilled as nasal drops and ear drops.
(15-20%) substances. Generally Shilajit contains 14-20%
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Int. J. Pharm. Sci. Rev. Res., 59(1), November - December 2019; Article No. 23, Pages: 140-143 ISSN 0976 – 044X
humidity, 18-20% minerals, 13-17% proteins, 4-4.5% in dyslipidemia, atherosclosis, breathing trouble, chronic
lipids, 3.3-6.5% steroids, 18-20% nitrogen free compounds, constipation, arthritic disorders, chronic dysmenorrhea or
1.5-2.0% carbohydrates and 0.5-0.8% alkaloids, amino pelvis pain, frequent urination, high blood pressure in
acids and other compounds10,12. alchoholism, tachycardia, oligospermia, piles antilithiatic
(stops formation of stones in kidney), carminative, mild
The chemical composition of Shilajit is a phytocomplex.
laxation, blood detoxifier, antiseptic, epilepsy, leucorrhea,
The components, humins, humic acids and fulvic acids, are
postrate enlargement, infertility due to oligospermia and
found in all Shilajit along with dilbenzo-α-pyrones which
antibacterial8,27,28.
act as carrier of other substances. The humaric substances
are the results of degradation of organic matter mainly Shilajit contains humic acid and iron which may help in
vegatable substances which is the results of the action of treating iron deficiency anemia and chronic fatigue
many microorganism. A large amount of benzoic acid, because it contains more than 85 different minerals as well
benzoates, hippuric acid and their salts as active as fulvic and humic acids. Because of the board spectrum,
substances are reported from Shilajit. Chemical Shilajit is thought to help the sickness of liver cancer. It is
investigation of Shilajit carried by Ali and co workers found that Shilajit helped the destruction of cancerous
furnished six compunds namely, shilajityl acetate, cells in the liver. Shilajit may also protect the heart and
shilajitol, silacatechol, silaxanthone, shilaanthranil and improve heart health. By taking Shilajit orally, reduce the
naphsilajitone. The other molecules present in Shilajit are obesity and this could mean less fatigue and more strength
lipids, steroids, carbohydrates, alkaloids, amino acids, free overtime. It has also been used to increase testosteron.
fatty acids, coloring matters such as carotenoids and Shilajit is also used externally for sprain, bruises, stops the
indigoids, coumarins, organic acids including adipic, itching and oozing of skin diseases and for inflammatory
succinic, citric, oxalic and tartaric acids, waxes, resins, swelling arthritis28.
polyphenols, essential oils, and vitamins like B and B 12,
CONCLUSION
eldagic acid, latex gums, albumins, triterpenes, sterols,
aromatic carbocylic acids, phenolic acids, tannoids and Shilajit is a naturally occurring multi-component with
lignins8,12,17-24. humous rich blakish brown substance which is widely used
in Indigenous system of medicine for the cure of variety of
Determination of heavy metals/minerals was carried out
diseases and to accelerate the process of rejuvenation. It
which gave the presence of Fe, Al, Zn, Cr, Mn, Mg, Co, Pb,
is mentioned and claimed as a panacea in classical texts. In
K and Ca. The percentage of these metals are very minimal
other words it means a remedy for all diseases or universal
amount which are permisiible level as prescribed by World
medicine. Shilajit was obtained in mountain regions as
Health Organisation (WHO) and not associated with health
exudates where the hilly tribes first identified its benifial
effects25.
use. It serves as potent tonic. Shilajit has nearly 85 ionic
Biological Investigations minerals and contains fulvic acid and humic acid together
with many phytochemicals. It is prescribed as the best
Shilajit, an ancient traditional medicine has been ascribed
Rasayana in Ayurvedic texts. The present communication
a number of biological activities for the treatment of
describes a comprehensive review on Shilajit highlighting
various diseases. It has been used as rejuvenator and
the significance, sources, definition, varieties,
adaptogen for thousands of years. Many therapeutic
mythological background, traditional uses, purification,
properties have been validated by modern scientific
physical and chemical investigation and biological
evalutaion. Fulvic acid is one of the major constituent of
evaluations. Apart from various claims regarding its
Shilajit. It is likely that the curative properties attributable
therapeutic activity, it is need of the day that further
to Shilajit are provided by the significant levels of fulvic
research be undertaken based on modern scientific
acids that Shilajit contains considering that fulvic acid is
methods. The presented data will be useful for further
known by its strong antioxidant actions and likely has
studies.
systemic effects as compliment activator. The fulvic acid in
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