DRUG OF CHOICE SERIES CENTRAL NERVOUS SYSTEM © Drug of choice for generalized absent seizure -Ethosuximide and Sodium valproate * Drug of choice for absence (Petit mal) seizures - Valproate © Drug of choice for absence seizures in children - Ethosuximide © Drug of choice for myoclonic seizures in men - Sodium Valproate © Drug of choice for myoclonic seizures in women - Lamotrigine © Drug of choice for focal seizure - Lamotrigine © Drug of choice for generalized tonic-clonic seizures (GTCS) - Lamotrigine © Drug of choice for tonic-clonic seizures - Sodium Valproate © Drug of choice for infantile seizures - ACTH © Drug of choice for rhinorrohea - Citrizine © Drug of choice for phobias - SSRI's © Drug of choice for reducing preanesthetic anxiety - Lorazepam * Drug of choice for status epilepticus - |.V Lorazepam © Drug of choice for febrile seizures - Diazepam * Drug of choice for partial seizures - Carbamazepine * Drug of choice for attention deficit hyperactivity disorder - Methylphenidate © Drug of choice for Alzheimer's disease - Rivastigmine © Drug of choice for obsessive-compulsive disorder (OCD) - Fluoxetine Drug of choice for drug-induced parkinsonism - Benzhexol * Drug of choice for parkinsonism - Ropinirole, Pramipexole © Drug of choice for glioma - Nitrosourea © Drug which has pain relief properties without opioid disadvantages - Tramadol * Drug of choice for sedation in patients with severe liver failure - Lorazepam © Drug of choice for maintenance treatment of generalized anxiety disorder - Buspirone © Drug of choice for febrile seizures - Diazepam © Drug of choice for endoscopic and colonscopy - MidazolamDrug of choice for hypnosis in elderly - Zolpidem © Drug of choice for diabetic neuropathy - Topiramate © Drug of choice for neuropathic pain - Lamotrigine or Topiramate or Gabapentin * Drug of choice for reducing alcohol craving - Naltrexone Drug for decreasing relapse of alcoholism - Acamprosate (NMDA receptor antagonist) or Naltrexone © Drug of choice for alcohol detoxification - Disulfiram * Drug of choice for smoking cessation - Bupropion © Drug of choice for depression in parkinson disease - SSRI's © Drug of choice for parkinson disease - Levodopa © Drug of choice for psycosis in parkinson disease - Clozapine © Drug of choice for depression - SSRI's Drug of choice for restless leg syndrome - Ropinirole * Drug of choice for violent behaviour - Haloperidol * Drug of choice for psychotic depression - Loxapine Drug of choice for neutropenia in felty's syndrome- Lithium * Drug of choice for patients with extra pyramidal symptoms (EPS) - Clozapine © Drug of choice for negative symptoms - Clozapine © Drug of choice for treatment resistant schizophrenia - Clozapine © Drug of choice for elderly with schizophrenia - Clozapine Drug of choice for peripheral neuropathy - Lamotrigine © Drug of choice for bulimia - SSRI's (Eg: Fluoxetine) Drug of choice for acute mania - Lithium © Drug of choice for serotonin syndrome - Cyproheptadine © Drug of choice for nocturnal enuresis - Desmopressin Drug of choice for major depression - SSRI's © Drug of choice for heat stroke - Chlorpromazine © Drug of choice for OCD - SSRI's or Clomipramine © Drug of choice for sleep walking - Carbamazepine © Drug of choice for cluster headache - Lithium © Drug of choice for cyclical vomiting - Lithium © Drug of choice for bipolar mood disorder - Lithium© Drug of choice for cerebral edema - Mannitol © Drug of choice for increased intracranial pressure - Mannitol * Drug of choice for psychomotor seizures - Carbamazepine © Drug of choice for mania - Lithium Carbonate © Drug of choice for Huntington chorea - Tetrabenazine © Drug of choice for Parkinsonism - Ropinirole and Pramipexole * Drug of choice for morning sickness - Hyoscine © Drug of choice for multiple sclerosis - Amitriptyline © Drug of choice for acute attack of migraine - Sumatriptan /Ergotamine © Drug of choice for night terrors - Benzodiazepines © Drug of choice for atypical depression - MAO inhibitors © Drug of choice for hydrocephalus - Glycerol or Acetazolamide * Drug of choice for cluster headache - Sumatriptan * Treatment of choice for cluster headache - High flow 02 © Drug of choice for infantile spasm - ACTH * Drug of choice for Huntington chorea - Tetra benzene © Drug of choice for multiple sclerosis - Interferon B * Drug of choice for pulmonary edema - Morphine Drug of choice generalized anxiety disorders - Diazepam (Benzodiazepines) © Drug of choice for pain in terminal illness - Morphine © Drug of choice for pain of acute myocardial infarction - Morphine * Drug of choice for chronic cancer pain - Morphine © Drug of choice for borderline personality disorder - Buspirone (5 HT partial agonist) © Drug of choice for neonate with respiratory depression due to use of morphine to control severe labour pain - Naloxone © Drug of choice for sedation in liver failure patients - Lorazepam * Drug of choice for decreasing anxiety in children preoperatively - Antihistaminics * Drug of choice for sedation in patients with porphyrias - Benzodiazepines © Drug of choice for trigeminal neuralgia - Carbamazepine © Drug of choice for status absence - Benzodiazepines * Drug of choice for convulsion in lidocaine treated patients - Diazepam © Drug of choice for tardive dyskinesia - Diazepam© Drug of choice for convulsion in tetanus patients - Diazepam © Drug of choice for delirium caused by ketamine — Diazepam HEMATOLOGY * Drug of choice for mierocytic anemia - Ferrous Sulfate © Drug of choice for iron deficiency anemia in pregnancy - Ferrous sulphate © Drug of choice for warfarin overdose - Vitamin K © Drug of choice for heparin overdose - Protamine sulphate © Drug of choice for hairy cell leukemia - Cladribine © Drug of choice for chronic lymphocytic leukemia - Fludarabine © Drug of choice for chronic myeloid leukemia (CML) - Imatinib © Drug of choice for chemotherapy-induced anemia - Erythropoietin © Drug of choice for anemia due to chronic kidney disease (CKD) - Erythropoietin drug of choive for autoimmune hemolytic anemia - Prednisolone * Drug of choice for transient ischemic attack (TIA) - Aspirin © Drug of choice for multiple myeloma - Melphalan © Drug of choice for heparin-induced thrombocytopenia - Argatroban © Drug of choice for chemotherapy-induced leukopenia - Sargramostim © Drug of choice for chemotherapy induced thrombocytopenia - Oprelvekin * First line drugs for multiple myeloma - Prednisolone, Prednisolone, Cyclophosphamide © Drug of choice for heparin-induced thrombocytopenia - Argatroban * Drug of choice for bleeding due to heparin - Hirudin * Drug of choice for warfarin overdose - Vitamin K © Drug of choice for heparin overdose - Protamine © Thrombolytic agent of choice in acute myocardial infarction - Streptokinase © Drug of choice for arterial fibrillation induced clotting - Warfarin © Drug of choice for prevention of stroke - Aspirin © drug of choice for prevention of deep vein thrombosis - Low molecularweight heparin (LMWH) © Drug of choice for preventing bleeding due to thrombolytic therapy - Epsilion amino capronic acid © Drug of choice for treatment of deep vein thrombosis - Low molecular weight heparin (LMWH) © Drug of choice for pulmonary embolism - Low molecular weight heparin (LMWH) © Drug of choice for anemia in chronic renal failure — Erythropoietin ANTICANCER DRUGS * Drug of choice for breast cancer - Tamoxifen © Drug of choice for glioma - Nitrosourea * Drug of choice for colorectal cancer - 5 Fluorouracil © Drug of choice for choriocarcinoma - Methotrexate © Drug of choice for pancreatic carcinoma - Gemcitabine * First line chemotherapy for cervix carcinoma - Cisplatin © Drug of choice for the brain tumor - Lomustine * Drug of choice for prostate carcinoma - Flutamide © Drug of choice for insulinoma - Streptozotocin © Drug of choice for polycythemia vera - Busulphan or Chlorambucil * Drug of choice for carcinoma of endometrium - Progestins © Drug of choice for kaposi sarcome - IF2 alpha © Drug of choice for CLL - Chlorambucil or Fludarabine * Drug of choice for acute myelocytic leukemia - Cytarabine with Mitoxantrone © Drug of choice for wilm's tumor - Vincristine with Danctinomycin © Drug of choice for acute promyeloblastic leukemia - Retinoic acid * Drug of choice for hairy cell leukemia - Cladarabine © Drug of choice for thyroid carcinoma — |-131 with Doxarubicin and cisplatin © Drug of choice for stomach cancer - Fluorouracil with Cisplatin * Drug of choice for CML - Imatinib or Busulfan © Drug of choice for acute lymphocytic leukemia(ALL) - Vincristine +Prednisolone + Mercaptopurine + Cyclophosphamide +Methotrexate * Drug of choice for ovarian cancer - Cisplatin with Paclitaxel © Drug of choice for lung cancer - Cisplatin with Taxane * Drug of choice for malignant melanoma - Dacarbazine © Drug of choice for testicular cancer - Bleomycin+ Etoposide + Cisplatin ANTIMICROBIAL DRUGS * Drug of choice for gram negative sepsis - Piperacillin with Toberamycin * Drug of choice for gram positive sepsis - Vancomycin with Gentamicin © Drug of choice for toxic shock syndrome (Group A strep.) - Penicillin with Clindamycin © Drug of choice for necrotizing fasciitis (Group A streptococcus) - Penicillin Drug of choice for prophylaxis of cardiac lesions in infective endocarditis - Amoxicillin * Drug of choice for impetigo - Penicillin G * Drug of choice for meningococcal meningitis - Penicillin G © Drug of choice for severe falciparum and chlorquinine resistant malaria - Quinine Drug of choice for enterococcus faecium - Linezolid * Drug of choice for animal bite - Amoxicillin © Drug of choice for otitis media - Amoxicillin * Drug of choice for dirty wound prophylaxis - Cefazolin © Drug of choice for pneumococcal pneumonia in adults - Amoxicillin © Drug of choice for typhus fever - Chloramphenicol © Drug of choice for lice infection - 1% permethrin © Drug of choice for dental prophylaxis in infective endocarditis - Clarithromycin * Drug of choice for cellulitis - Oxacillin © Drug of choice for severe infection in penicillin allergic patient - Vancomycin * Drug of choice for microspora - Albendazole © Drug of choice for serious upper urinary tract infections -Aminoglycosides © Drug of choice for serious upper respiratory infections by atypical pathogens - Doxycycline © Drug of choice for endocardial prophylaxis in patients allergic to penicillin - Vancomycin © Drug of choice for histoplasmosis - Amphotericin B © Drug of choice for invasive streptococcal infection - Clindamycin © Drug of choice for dermatitis herpetiformis - Aspirin © Drug of choice for cryptoccocus - Fluconazole * Drug of choice for vulvovaginal candidiasis - Fluconazole © Drug of choice for pyrazinamide induced hyperuricemia - Aspirin © Drug of choice for systemic fungal infection - Amphotericin B * Drug of choice for CMV retinitis - Gancyclovir © Drug of choice for condyloma accuminata - Podophyline © Drug of choice for cholera - Doxycycline © Drug of choice for chlamydiae - Tetracycline ( Eg:Doxycycline) * Drug of choice for tropical sprue - Tetracycline © Drug of choice for relapsing fever - Tetracycline © Drug of choice for rocky spotted mountain fever - Tetracycline © Drug of choice for tick typhus - Tetracycline * Drug of choice for scrubs typhus - Tetracycline © Drug of choice for syphilis - Penicillin G © Drug of choice for toxoplasmosis - Cotrimoxazole © Drug of choice for legionella - Azithromycin or Levofloxacin © Drug of choice for lymphogranuloma venereum (LGV) - Azithromycin © Drug of choice for kala-azar - Sodium Stibogluconate * Oral drug of choice for kala-azar - Miltefosine © Drug of choice for plague - Streptomycin © Drug of choice for brucella - Streptomycin © Drug of choice for tularemia - Streptomycin © Drug of choice for rhinoscleroma - Streptomycin © Drug of choice for actinomycosis - Penicillin-G * Drug of choice for leprosy - Dapsone © The most effective drug against Mycobacterium leprae — Rifampicin© Drug of choice for herpes zoster - Valaciclovir © Drug of choice for herpes simplex - Acyclovir * Drug of choice for influenza - Oseltamivir © Drug of choice for blood fluke - Praziquantel © Drug of choice for lung fluke - Praziquantel Drug of choice for typhoid (Enteric fever) - |.V Ceftriaxone * Drug of choice for leptospirosis - Penicillins © Drug of choice for Plasmodium vivax - Chloroquine * Drug of choice for Plasmodium falciparum - Artemisinin combination therapy (Artesunate + Pyrimethamine + Sulfadoxine) © Drug of choice for cerebral malaria - Artesunate © Drug of choice for malaria - Chloroquine © Drug of choice for chloroquine-resistant malaria - Artemisinin combination therapy (Artesunate + Pyrimethamine + Sulfadoxine) Drug of choice for brucella - Streptomycin with doxycycline © Drug of choice for candida - Fluconazole * Drug of choice for aspergillosis - Voriconazole © Drug of choice for dermatophytosis- Topically (Azole), Systemic (Griseofulvin) * Drug of choice for Chagas disease - Nifurtimox, Benznidazole © Drug of choice for dysuria - Phenazopyridine © Drug of choice for gonorrhea - Procaine Peni * Drug of choice for syphilis - Procaine penicillin * Drug of choice for rickettsial infection - Tetracycline © Drug of choice for plague - Tetracycline © Drug of choice for anthrax - Doxycycline © Drug of choice for toxoplasmosis - Trimethoprim Sulphamethoxazole * Drug of choice for Haemophilus influenza type B - Rifampicin © Drug of choice for prophylaxis of tuberculosis - Isoniazid © Drug of choice for diarrhea in HIV patient - Octreotide © Drug of choice for acyclovir-resistant herpes - Foscarnet * Drug of choice for hepatitis B - Limuvidine © Drug of choice for hepatitis C - Ribavarine & Interferon 2 alpha © Drug of choice for lava migrans - Albendazole * Drug of choice for inflammatory - Sulphasalazine* Drug of choice for prophylaxis of newborn to TB mother - INH © Drug of choice for accidental exposure of HIV to health care workers — Zidovudine with Lamivudine * Drug of choice for salmonella - Ceftriaxone * Drug of choice for meningitis - Ceftriaxone © Drug of choice for gonorrhea - Ceftriaxone Drug of choice for resistant pneumococcal infections - Ceftriaxone Second line drug of choice for filariasis - |vermectin Drug of choice for tapeworm infestation - Praziquantel © Drug of choice for strongyloidiasis (Threadworm) - lvermectin © Drug of choice for onchocerciasis (River Blindness) - lvermectin © Drug of choice for tetanus - Metronidazole © Drug of choice for listeria Ampicillin * Second line drug of choice for listeria - SMZ -TMP (Sulphamethoxazole Trimethoprim) © Drug of choice for MRSA - Vancomycin © Drug of choice for vancomycin - resistant staph aureus (VRSA) - Linezolid * Drug of choice for neonatal meningitis - Ampicillin + 3rd generation Cephalosporin * Drug of choice for bacteriosides fragialis - Clindamycin © Drug of choice for pseudomembranous colitis - Metronidazole * Drug of choice for amebiasis - Metronidazole * Drug of choice for trench mouth - Metronidazole * Drug of choice for bacterial vaginosis - Metronidazole © Drug of choice for amoebic liver disease - Metronidazole © Drug of choice for trichomoniasis - Metronidazole © Drug of choice for giardiasis - Metronidazole * Drug of choice for extraluminal amebiasis - Metronidazole * Drug of choice for antibiotic-induced colitis - Metronidazole © Drug of choice for anaerobic infections - Metronidazole * Drug of choice for gonorrhea - Ceftriaxone © Drug of choice for H.pylori eadication - Metronidazole © Drug of choice for whooping cough - Erythromycin * Drug of choice for cat scratch disease - Erythromycin © Drug of choice for campylobacter infections - Erythromycin© Drug of choice for gonococcal urethritis - Azithromycin © Drug of choice for chancroid - Azithromycin © Drug of choice for legionellosis - Azithromycin © Drug of choice for trachoma - Azithromycin © Drug of choice for inflammed acne - Minocycline * Drug of choice for cystic acne - Isotretinoin Drug of choice for urinary tract infection - Norfloxacin © Drug of choice for scabies - Permethrin * Oral drug of choice for scabies - lvermectin © Drug of choice for filariasis - Diethyl Carbamazine (DEC) * Drug of choice for listeria monocytogenes - Ampicillin © Drug of choice for enterococcus fecalis - Ampicillin © Drug of choice for toxoplasmosis - Cotrimoxazole Drug of choice for toxoplasmosis in pregnancy - Spiramycin © Drug of choice for schistosomiasis - Praziquantel © Drug of choice for leishmaniasis - Amphotericin B * Drug of choice for Aspergillosis - Amphotericin B © Drug of choice for roundworm (Ascaris) - Albendazole (Anti helminthic agent) © Drug of choice for pinworm (Enterobius vermicularis) - Albendazole (Anti helminthic agent) © Drug of choice for hookworm - Albendazole (Anti helminthic agent) Drug of choice for whip worm - Albendazole (Anti helminthic agent) © Drug of choice for trichinae worm (Trichinella spiralis) - Albendazole (Anti helminthic agent) © Drug of choice for guinea worm (Dracunculus medinensis) - Albendazole (Anti helminthic agent) © Drug of choice for hydatid disease - Albendazole © Drug of choice for filarial worm - Ivermectin (Anti helminthic agent ) © Drug of choice for threadworm (Strongyloides stercoralis) - lvermectin (Anti helminthic agent) © Drug of choice for pork tapeworm (Taenia solium) - Praziquantel © Drug of choice for beef tapeworm (Taenia saginata) - Praziquantel© Drug of choice for fish tapeworm (Diphyllobothrium latum ) - Praziquantel * Drug of choice for dog tapeworm (Echinococcus granulosus) - Praziquantel © Drug of choice for dwarf tapeworm (Hymenolepis nana) - Praziquantel © Drug of choice for liver fluke (Fasciola hepatica) - Triclabendazole * Drug of choice for blood fluke - Praziquantel © Drug of choice for lung fluke - Praziquantel © Drug of choice for community acquired pneumonia - Clarithromycin * Drug of choice for surgical prophylaxis - Cefazolin © Drug of choice for pneumocystis carnii - Cotrimoxazole © Drug of choice for cholera in children - Cotrimoxazole © Drug of choice for filarial worm — Di-Ethyl Carbamazepine © Drug of choice for Platyhelminthes - Praziquantel © Drug of choice for trichomoniasis - Metronidazole © Drug of choice for extended spectrum bacterial lactamase - Carbapenem © Drug of choice for otitis media - Amoxicillin * Drug of choice for Nocardia - Sulfonamides © Drug of choice for neurosyphilis - Aqueous penicillin © Drug of choice for donovanosis - Azithromycin or Doxycycline * Drug of choice for Neisseria - Ceftriaxone © Drug of choice for Cryptococcus - For induction( Amphotericin), for maintenance (Fluconazole) * Drug of choice for Neurocysticercosis - Albendazole * Drug of choice for typhoid (Enteric fever) - LV Ceftriaxone ° First line drugs for tuberculosis - Rifampicin, |soniazid, Pyrazinamide, Ethambutol, Streptomycin (RIPES) Drug of choice for tuberculosis in renal failure - Rifampicin * Drug of choice for prevention of tuberculosis in susceptible individuals - INH © Drug of choice for treatment of tuberculosis in HIV positive patients taking protease inhibitor - Rifabutin © Drug of choice for MDR strains of tuberculosis - Amikacin © Drug of choice for latent tuberculosis - INH * Drug of choice for INH resistant patients of latent tuberculosis - Rifampin© Drug of choice for leprosy - Rifampin © Drug of choice for lepra 1 reaction - Glucocorticoids Drug of choice for lepra 2 reaction - Glucocorticoids © Treatment of choice for multibacillary leprosy - Rifampin with Dapsone & Clofazamine © Drug of choice for hot water born tuberculosis in hospital (M.xenopi)- Clarithromycin © Drug of choice for cutaneous TB caused by atypical mycobacteria - Clarithromvcin. © Drug of choice for meningococcal prophylaxis - Ciprofloxacin © Drug of choice for meningococcemia - Ceftriaxone © Drug of choice for post spleenectomy sepsis — Ceftriaxone POISONING © Drug of choice for paracetamol poisoning - N-Acety! cysteine © Drug of choice for organophosphate poisoning - Atropine * Drug of choice for methotrexate toxicity - Folinic Acid * Drug of choice for ethylene glycol poisoning - Fomepizole © Drug of choice for warfarin poisoning - Vitamin K © Drug of choice for heparin poisoning - Protamine sulphate © Drug of choice for acute mercury - Dimercaprol © Drug of choice for theophylline poisoning - Beta blockers © Drug of choice for iron poisoning - Deferoxamine © Drug of choice for copper poisoning - D- Penicillamine or Zinc acetate * Drug of choice for acute arsenic poisoning - Dimercaprol © Drug of choice for carbamate poisoning - Atropine * Drug of choice for calcium channel blocker poisoning - Calcium with Glucagon © Drug of choice for lead poisoning - DMSA © Drug of choice for anticholinergic drug poisoning - Physostigmine © Drug of choice for methylxanthines poisoning - Beta blocker © Drug of choice for ergot alkaloid poisoning - Sodium nitroprusside © Drug of choice for alpha 1 agonist poisoning - Phentolamine* Drug of choice for beta 2 agonist poisoning - Propranolol * Drug of choice for carbon dioxide poisoning - Hyperbaric oxygen Drug of choice for chronic mercury poisoning - N-acetyl- penicillamine * Drug of choice for Beta blocker poisoning - Glucagon © Drug of choice for antipsychotic poisoning - Sodium bicarbonate with lidocaine * Drug of choice for INH poisoning - Vitamine B6 * Drug of choice for cyanide poisoning - Amyl Nitrate Drug of choice for opiod overdose — Naloxone Drug of choice for aspirin poisoning - Vitamin K fresh frozen plasma © Drug of choice for benzodiazepines poisoning - Flumazenil * Drug of choice for iodine poisoning — Starch RESPIRATORY SYSTEM © Drug of choice for COPD - Anticholinergics (Eg:Tiotropium) First line drugs for tuberculosis - Rifampicin, Isoniazid, Pyrazinamide, Ethambutol, Streptomycin (RIPES) * Drug of choice for testing bronchial hyperactivity - Methacholine (Non- selective muscarinic receptor agonist) © Drug of choice for pulmonary edema with Congestive heart failure (CHF) - Furosemide (Diuretic) * Drug of choice for a vasodilatory shock - Norepinephrine © Drug of choice for persistent hiccups - Carbon Dioxide © Drug of choice for apnea in premature infants - Theophylline © Drug of choice for exercise induced asthma - Mast cell stabilizers (Eg: Sodium Cromoglycate) © Drug of choice for asprin induced asthma - Leukotriene antagonist (Eg: Montelukast) Drug of choice for starting treatment of asthma - Inhaled beta 2 agonist (Eg: salmeterol) © Drug of choice for bronchospasm with COPD - Ipratropium Bromide © Drug of choice for smoking cessation - Nicotine * Drug of choice for liquefying plaques of sputum in patients with cysticfibrosis - Acetylcysteine * Drug of choice for temporal arteritis - Corticosteroid © Drug of choice for prophylaxis of exercise induced asthma - Sodium chromoglycate © Drug of choice for pulmonary edema - Furosemide * Drug of choice for dry itchy cough - Codeine © Drug of choice for acute asthma attack - Salbutamol (Short acting Selective Beta2-adrenergic receptor agonist) © Drug of choice for persistent asthma - Inhaled corticosteroid © Drug of choice for an asthmatic patient with hypertension - Amlodipine © Drug of choice for Pneumocystis carinii - Cotrimoxazole © Drug of choice for suppression of cough - Dextromethorphan © Drug of choice for ACE inhibitor induced cough - Asprin © Drug of choice for asthma in diabetes - |pratropium * Drug of choice for beta blocker induced bronchospas — Ipratropium bromide © Drug of choice for mild persistent - Inhaled low dose corticosteroid or Mast cell stabilizers or leukotrienes antagonist * Drug of choice for moderate persistent asthma - Inhaled corticosteroid with long acting beta 2 agonist * Drug of choice for severe persistent asthma - High dose Inhaled corticosteroid (ICS) + Long acting beta 2 agonists (LABA) + Oral corticosteroid © Drug of choice for poorly controlled asthma - Theophylline © Drug of choice for prophylaxis of asthma - Sodium cromoglycate ( Mast cell stabilizer) CARDIOVASCULAR SYSTEM Drug of choice for digoxin toxicity - Potassium 1st line drug of choice for CHF- ACE inhibitors (Eg : Captopril ,Enalapril) © Drug of choice for rapid fast diuresis - Loop diuretics (Eg: Furosemide) © Drug of choice for multi-focal atrial tachycardia - Verapamil (Calcium channel blocker)© Drug of choice for paroxysmal supra-ventricular tachycardia (PSVT) - Adenosine (Anti-arrhythmic agent) * Drug of choice for supra-ventricular tachycardia (SVT) - Verapamil © Drug of choice for digitalis-induced ventricular arrhythmia - Lignocaine (Anti-arrhythmic agent) © Drug of choice for ventricular arrhythmias - Lidocaine Drug of choice for ventricular tachycardia and fibrillation - Lidocaine © Drug of choice for ventricular extra-systole - Beta blocker (Eg: Atenolol) © Drug of choice for atrial fibrillation - Digitalis © Drug of choice for maintaining sinus rhythm - Amiodarone (Anti- arhythmic agent) * Drug of choice for Wolff- Parkinson-white syndrome - Procainamide or Amiodarone © Drug of choice for digitalis-induced arrhythmia - Lignocaine * Drug of choice for acute left ventricular failure - |.V Furosemide © Drug of choice for the scleroderma induced hypertensive crisis - ACE inhibitors * Drug of choice for acute long QT syndrome - MgSO4 © Drug of choice for congenital long QT syndrome - Beta blocker * Drug of choice for hypertension with peripheral vascular disease - Calcium channel blockers © Drug of choice for the Hypertensive emergency - Sodium nitroprusside (Vasodilator) © Drug of choice for malignant hypertension - Nitroprusside (Vasodilator) © Drug of choice for producing controlled hypotension - Sodium nitroprusside © Drug of choice for pulmonary hypertension - Bosentan © Drug of choice for atrial flutter and fibrillation - Ibutilide * Drug of choice for paradoxical tachycardia - Digoxin (Digitalis glycosides) © Drug of choice for angina - Nitrates (Vasodilator) © Drug of choice for prophylaxis of stable angina - Beta blockers © Drug of choice for variant angina - Calcium channel blockers (Eg: Verapamil) * Drug of choice for the cardiogenic shock with renal failure - Dopamine © Drug of choice for pulmonary edema with Congestive heart failure (CHF)- Furosemide (Loop diuretic) Drug of choice for rheumatic fever — Benzathine, Penicillin © Drug of choice for TOF - Morphine © Drug of choice for reducing mortility in CHF - Spironolactone © Drug of choice for inotropic effect - Dobutamine © Drug of choice for a hypertensive patient with benign prostatic hyperplasia(BPH) - Alpha 1 Blocker (Eg: Prazosin, Terazosin, Doxazosin, Alfuzosin) © Drug of choice for perioperative arrhythmias - Esmolol (Cardio selective beta blocker) URINARY SYSTEM * Drug of choice for RPGN - Cyclophosphamide © Drug of choice for lupus nephritis - Cyclophosphamide © Drug of choice for nephrotic syndrome - Steroids © Drug of choice for steroid-resistant nephrotic syndrome - Cyclosporine © Drug of choice for steroid-dependent nephrotic syndrome - Cyclophosphamide * Drug of choice for urinary retention - Bethanechol © Drug of choice for enuresis - Imipramine © Drug of choice for hemorrhagic cystitis - Mesna * Drug of choice for patient allergic to thiazides and loop diuretics - Ethacrynic acid © Drug of choice for forced alkaline diuresis - Furosemide © Drug of choice for cerebral edema - Mannitol (Osmotic diuretic ) © Drug of choice for malignant hypertension - Furosemide © Drug of choice for edema in liver cirrhosis - Furosemide © Drug of choice for hypercalcemia - Furosemide (Loop diuretic ) © Drug of choice for edema in congestive heart failure - Furosemide © Drug of choice for edema in renal failure - Furosemide © Drug of choice for idiopathic hypercalciuria - Thiazide (Eg: hydrochlorothiazide) * Drug of choice for calciuria due to hyperparathyroidism - Thiazides* Drug of choice for nephrogenic diabetes insipidus - Thiazides * Drug of choice for lithium induced nephropathy - Thiazides * Drug of choice for hyperuricemia in renal failure - Allopurinol * Drug of choice for gout in renal failure - Allopurinol © Drug of choice for lesh nyhan syndrome - Allopurinol © Drug of choice for urate nephropathy - Allopurinol (Xanthine oxidase inhibitor) © Drug of choice for alkalization of urine - Acetazolamide © Drug of choice for Conn’s syndrome primary hyperaldosteronism - Spironolactone * Drug of choice for secondary hyperaldosteronism - Spironolactone * Drug of choice for thiazide induced hypoklemia — Spironlactone OPTHALMOLOGY © Drug of choice for open-angle glaucoma - Prostaglandins analogs © Drug of choice for closed-angle glaucoma - Acetazolamide © Drug of choice for secondary glaucoma - Beta blocker * Drug of choice for inclusion conjunctivitis - Ceftriaxone © Drug of choice for trachoma - Azithromycin © Drug of choice for primary open angle glaucoma (POAG) - Timolol © Drug of choice for Xerostomia - Cevimeline © Drug of choice for corneal ulcer - Cyclopentolate * Drug of choice for hypertension with glaucoma - Timolol © Drug of choice for iridocyclitis - Atropine * Which beta blocker is the drug of choice in open angle glaucoma - Timolol © Drug of choice for hepatic keratitis - Idoxuridine © Drug of choice for fungal corneal ulcer - Natamycin © Drug of choice for uveal herpetic keratitis - Acyclovir * Drug of choice for preventing meiosis during cataract surgery - Flurbiprofrn * Drug of choice for mild allergic conjunctivitis - Topical antihistaminics © Drug of choice for decreasing intra ocular pressure before surgery —Osmotic diuretics (Eg: Manitol) © Drug of choice for decreasing high intra ocular pressure - Osmotic diuretics © Drug of choice for recurrent anterior uveitis - NSAID's © Drug of choice for reducing intra ocular pressure in diabetes - Osmotic diuretics ENDOCRINOLOGY © Drug of choice lithium-induced diabetes mellitus - Amiloride © Drug of choice for steroid-induced osteoporosis - Zolindrate (Bisphosphonates) © Drug of choice for prostate cancer - GNRH Analogues (Eg: buserelin ) * Drug of choice for neurogenic diabetes insipidus - Desmopressin * Drug of choice for nephrogenic diabetes insipidus - Thiazides © Drug of choice for acute adrenal insufficiency - Hydrocortisone (I.V) © Drug of choice for postprandial hyperglycemia - Nateglinide (Maglitinide derivative) © Drug of choice for type 2 diabetes mellitus (DM) - Metformin (Bigunides) © Drug of choice for type | diabetes mellitus (DM) - Regular Insulin © Drug of choice for diabetes mellitus in pregnancy - Regular Insulin © Drug of choice for uncontrolled diabetes mellitus - Regular Insulin © Drug of choice for diabetic ketoacidosis - Regular Insulin © Drug of choice for diabetes in renal and hepatic failure - Regular Insulin * Drug of choice for diabetes in renal failure - Repaglinide ( Maglitinide derivative) © Drug of choice for prevention of breast cancer - Tamoxifen © Drug of choice for prevention of diabetes - Metformin * Drug of choice for severe hypoglycemia in case of insulinoma - Diazoxide (Potassium channel opener) *Drug of choice for emergency contraception - Mifepristone Drug of choice for polycystic ovarian disease - Clomiphene citrate © Drug of choice for oligospermia - Clomiphene citrate * Drug of choice for corpus luteum insufficiency - Clomiphene citrate© Drug of choice for anovulatory infertility - Clomiphene citrate * Drug of choice for post coital contraception - Mifepristone © Drug of choice for hirsutism - Cyproterone acetate (Androgen receptor antagonist) * Drug of choice for large prostate - Finasteride ( 5 alpha reductase inhibitor) © Drug of choice for inducing labour - Oxytocin * Drug of choice for BPH - Tamsulosin * Drug of choice for postmenopausal osteoporosis - Raloxifene or Bisphosphonates © Drug of choice for acute & chronic adrenal insufficiency - Hydrocortisone (Shortest acting glucocorticoid) * Drug of choice for congenital adrenal hyperplasia - Hydrocortisone © Drug of choice for tumor induced brain edema - Dexamethasone ( Long acting glucocorticoid ) © Drug used for mineralocorticoid replacement - Fludrocortisone © Drug of choice for Premenstrual syndrome - SSRI's (Eg: Fluxetine) © Drug of choice for dysfunctional uterine bleeding - NSAIDS © Drug of choice for androgenic alopecia - Finasteride (5 Alpha reductase inhibitor) © Drug of choice for hypothyroidism - Levothyroxine © Drug of choice for hypothyroidism in children (cretinism) - Thyroxine © Drug of choice for myxedema coma - Levothyroxine © Drug of choice for reducing thyroid gland vascularity - Potassium iodide © Drug of choice for hyperprolactinemia - Bromocriptine © Drug of choice for acute gout - NSAID (Indomethacin) © Drug of choice for chronic gout - Allopurinol (Xanthine oxidase inhibitor) * Drug of choice for thyroid storm - Propylthiouracil © Drug of choice for making patient euthyroid before surgery - Potassium iodide * Drug of choice for thyroid cancer - Levothyroxine © Drug of choice for grave's disease - Methimazole (Antithyroid drug) © Drug of choice for thyroid ablation - | 131 * Drug of choice for thyroid storm in India - Potassium iodide © Drug of choice for reducing somatic manifestations of hyperthyroidism -Propranolol © Drug of choice for diabetic ketoacidosis (DKA) - Regular Insulin © Drug of choice for pheochromocytoma - Phenoxybenzamine (Alpha blocker) © Drug of choice for acute hypercalcemia - Furosemide (Loop diuretic) * Drug of choice for hypercalcemia due to malignancy - Bisphosphonate PREGNANCY © Drug of choice for ectopic pregnancy - Methotrexate © Drug of choice for induction of labor - Oxytocin * Drug of choice for postpartum hemorrhage - Oxytocin © Drug of choice for hypertension in pregnancy — Alpha Methyldopa © Drug of choice for endometriosis - Danazol © Drug of choice for asthma - Beta 2 agonists © Drug of choice for postpartum breast engorgement - Oxytocin © Drug of choice for seizures in eclampsia - Magnesium sulphate © Drug of choice in seizures during pregnancy- Phenobarbitone © Drug of choice for the hypertensive emergency in pregnancy - Labetalol * Drug of choice for postpartum hemorrhage - Oxytocin © Drug of choice for falciparum malaria in pregnancy - Quinine © Drug of choice for cerebral malaria - Quinine Drug of choice for gonorrhea - Penicillin or Ceftriaxone © Drug of choice for toxoplasmosis in pregnancy - Spiramycin © Drug of choice for malaria in pregnancy - Chloroquine © Drug of choice for acne - Erythromycin (oral ) / Benzylbenzoate (Topical) © Drug of choice for epilepsy in pregnancy - Phenobarbitone © Drug of choice for mania in pregnancy - Olanzapine © Drug of choice for hyperthyroidism - Propylthiouracil © Drug of choice for hypothyroidism - Levothyroxine © Drug of choice for bacterial vaginosis in 1st trimester - Clindamycin © Drug of choice cholera in pregnancy - Furazolidone© Drug of choice for typhoid fever in pregnancy - Ceftrixone or Ampicillin © Drug of choice for amoebiasis - Metronidazole ( Contraindicated in 1st trimester) © Drug of choice for amoebiasis in Ist trimester - Furazolidone Drug of choice for preventing neural tube defect - Folic acid * Drug of choice for anticoagulation in pregnancy - Heparin © Drug of choice for mania - Lithium Drug of choice for mysthenia gravis - Neostigmine * Drug of choice for thromboflebitis - Aspirin Drug of choice for urinary tract infection during pregnancy - Ampicillin Drug of choice for HIV in pregnancy - Zidovudine and Nevirapine © Drug of choice for resistant typhoid - Ceftriaxone Drug of choice for tuberculosis - INH with rifampicin Drug of choice for vitamin B12 deficiency - Cynacobalamin © Drug of choice for iron deficiency - Ferrous sulphate © Drug of choice for antiplatelet action - Aspirin © Drug of choice for anxiety - Benzodiazepines © Drug of choice for pain - Aspirin / Paracetamol © Drug of choice for depression in pregnancy - Tricyclic antidepressant © Drug of choice for superficial thrombophlebitis - Asprin © Drug choice for bacterial vaginosis in 1st trimester in pregnancy - Clindamycin * Drug choice for rosacea - NSAIDS Drug choice for rheumatoid arthritis - Aspirin Drug choice for schizophrenia - Phenothiazines (Eg: Haloperidol) Drug choice for seborrhic dermatitis - Salicylic acid DERMATOLOGY © Drug of choice for taenia - Topical azoles (Eg: clotriamazole) © Drug of choice for erythrodermic psoriasis - Methotrexate © Drug of choice for psoriatic arthropathy - Methotrexate © Drug of choice for severe psoriasis - Methotrexate© Drug of choice for severe erythrodermic psoriasis - Cyclosporine © Drug of choice for pustular psoriasis - Retinoid © Drug of choice for impetigo herpetiformis - Systemic Steroids © Drug of choice for dermatitis herpetiformis - Dapsone * Treatment of choice for subacute eczema - Creams & Moisturizers ¢ Treatment of choice for chronic eczema - Ointment * Drug of choice for impetigo - Mupirocin © Drug of choice for solar lentigenes - Tretinoin © Drug of choice for chancroid - Ceftriaxone * Drug of choice for pemphigus vulgaris - Prednisolone * Drug of choice for vitiligo - Corticosteroids © Drug of choice for atopic dermatitis - Topical corticosteroids Drug of choice for severe excerebation of atopic dermatitis - Systemic corticosteroids © Drug of choice for reducing recurrence of melanoma - Alpha interferon with vaccine © Drug of choice for lichen simplex chronicus - Corticosteroids * Drug of choice for seborrhic dermatitis in scalp - Selenium shampoo * Drug of choice for acne rosacea - Oral tetracycline © Drug of choice for tinea capitis - Griseofulvin © Drug of choice for the scleroderma induced hypertensive crisis - Ace inhibitors (Eg:Captopril, Enapril etc) © Treatment of choice for lichen planus - Topical glucocorticoids * Drug of choice for systemic dermatophytosis — Griseofulvin