TWITTER REVIEW CENTER 𝐆lucocorticoid zona 𝐑eticularis = 𝐒𝐞𝐱
Compiled by: SlicesOfMedtech steroids
Credits to the owners
Cardiac markers: Order of Elevation
CLINICAL CHEMISTRY during Myocardial Infarction (MI)
𝐇𝐀𝐗𝐈 𝐕𝐎𝐘𝐃 𝐌𝐲𝐓𝐫𝐨𝐩𝐢𝐂𝐀𝐋
HAXI = Horizontal, Abscissa, X-axis, 𝐌𝐲oglobin
Independent variable
𝐓𝐫𝐨𝐩onin
VOYD = Vertical, Ordinate, Y-axis,
Dependent variable 𝐂K
𝐀ST
ACID BASE: 𝐑𝐎-𝐌𝐄 𝐋DH
Respiratory-Opposite • Metabolic-
Equal
Gaussian Curve
- data elements are centered around
𝐓𝐀𝐌-𝐒𝐏𝐅 the MEAN
T = T-test - total area under the curve: 1.0 or
100%
A = Accuracy
CUSUM
M = Mean
- detects systematic error (trend
S = SD (Standard Deviation) only!!!)
P = Precision Youden/Twin Plot
F = F-test - compare results obtained on high
and low control serum from different
labs (2 sets)
Shewhart Levey Jennings Chart
ADRENAL CORTEX: 𝐆𝐨 𝐅𝐢𝐧𝐝 𝐑𝐞𝐱 - "dot chart"
and 𝐌𝐚𝐤𝐞 𝐆𝐨𝐨𝐝 𝐒𝐞𝐱 zona 𝐆lomerulosa
= 𝐌ineralocorticoid zona 𝐅asciculata =
- most widely used and ✨best✨ QC chart 13s - detects imprecision AND
for daily monitoring of accuracy and systematic bias
precision
R4s - detects imprecision (detectable
- easily identifies random and within a single run)
systematic errors
22s - detects bias
41s and 81s - detects bias trend
Main Causes of:
10x - not recommended as rejection
TREND - Deterioration of reagents rule
SHIFT - Improper calibration of 💭 Main Goal of Six Sigma ➜ reduction
instrument of the number of effects to near zero
OUTLIERS - Pipetting error 💭 Main Goal of Lean System ➜
elimination/reduction of non valued
activities
Only statistics seen in QC chart: 💭 Proponent of Lean System ➜
MOTOROLA
1. SD
3 types of POCT:
2. Mean
Verifying Ref. Intervals - 20 study 1️⃣ Wet Chem - liquid reagent
individuals
2️⃣ Cartridge Based
Establishing Ref. Intervals - 120
study individuals 3️⃣ Strip Based - most common
T-Test - compare means or accuracy
F-Test - compare SD or precision Remember! Hemolysis as the cell
bursts. Help KLAMP the leak!
Control value between 2s and 3s -
Potential problem K - K+
Control value outside 3s - Require L - LD
corrective action
A - Aldolase (ALD)
2s - Warning limit
Acid Phosphatase (ACP)
3s - Error limit
M - Mg+
12s - warning rule (not
recommended for rejection rule) P - PO4
All causes an increase in serum Lactic acidosis
glucose
Unmeasured ions
REMEMBER ✨GAG CHET✨
Methanol
Glucagon
Polyenthylene glycol
ACTH
Ethanol
Growth Hormone
Diabetic ketoacidosis
Cortisol
Human Placental Lactogen
Remember the 👀STEROID
Epinephrine BROTHERS👀 Cushy Carl (Cushing
Disease)
T3 and T4
glucose and cortisol
Na+ and urinary steroids
‼️PROTEIN ELECTROPHORESIS‼️
ALD
Abbie ALBUMIN is attracted to Andy
cUshy the problem is Up (letter U)
ANODE because of his POSITIVE
attitude Anemic Addison (Addison's dx)
Na+ and Cl
Hgb (anemica) ALD, Urinary steroids
Elevated Liver Enzymes are as Easy as
✨ABC✨
Alcohilism ‼️CC Tumor Markers‼️
Biliary Obstruction Ideal Tumor Marker are:
Cirrhosis Ca. sensitive
Specific
Conditions Causing in Unmeasured Tx specific
Anions (ethanol, ketones, etc.)
Detectable in blood
✨SLUMPED✨
Salicylate intoxication
MICROBIOLOGY
PLASMODIUM SPP.: Sina
𝐅𝐞𝐫𝐝𝐢𝐧𝐚𝐧𝐝 𝐌𝐚𝐫𝐜𝐨𝐬 at 𝐕𝐢𝐥𝐦𝐚
𝐒𝐚𝐧𝐭𝐨𝐬 ay nagdate sa 𝐌𝐚𝐧𝐢𝐥𝐚 𝐙𝐨𝐨
habang umiinom ng 𝐎𝐫𝐚𝐧𝐠𝐞 𝐉𝐮𝐢𝐜𝐞
FM = Falciparum • Maurer dots
VS = Vivax • Schüffner's dots
PLASMODIUM SPP. MZ = Malariae •
Ziemann dots OJ = Ovale • James dots
SCHISTOSOMA: 𝐌𝐑 𝐇𝐔𝐉𝐈
MR = Mansoni • Rectum
HU = Haematobium • Urinary Bladder
JI = Japonicum • Intestine
Rapid Lactose Fermenters: 𝐄𝐊𝐄
• Escherichia
• Klebsiella
• Enterobacter
Late Lactose Fermenters: 𝐂𝐇𝐒𝐒𝐒𝐘
• Citrobacter H2S (+): 𝐒𝐏𝐀𝐂𝐄𝐝
• Hafnia • 𝐒almonella
• Salmonella arizonae • 𝐏roteus
• Shigella sonnei • 𝐀rizonae
• Serratia • 𝐂itrobacter freundi
• Yersinia enterocolitica • 𝐄𝐝wardsiella tarda
Non Lactose Fermenters: 𝐏𝐏𝐌-𝐄𝐄- Key Characteristics of Streptococcus
𝐒𝐒 pneumoniae infection: 𝐌𝐎𝐏𝐒
• Proteus 𝐌eningitis
• Providencia 𝐎titis media
• Morganella 𝐏neumonia
• Edwardsiella 𝐒inusitis
• Erwinia
𝙶𝙴𝙽𝙴𝚁𝙰𝙻 𝙸𝙽𝙵𝙾:
• Salmonella
• Gram (+)
• Shigella
• Lancet- or bullet-shaped diplococci
• Encapsulated
Non Lactose Fermenters: 𝐏𝐏𝐌-𝐄𝐄-
𝐒𝐒 • α-hemolytic
• Proteus
• Providencia DNAse Test (+): 𝐒𝐒𝐒 𝐌𝐨 (if gram +
cocci only)
• Morganella
𝐒taphylococcus aureus
• Edwardsiella
𝐒treptococcus pyogenes
• Erwinia
𝐒erratia
• Salmonella
𝐌𝐨raxella
• Shigella
or
DNAse Test (+): 𝐒𝐌𝐀𝐒𝐇 𝐕𝐒𝐒 (all)
Serratia
Moraxella
Aeromonas 📌 IMPORTANT: IMViC 📌
Stenotrophomonas Indole (+): 𝐌𝐚𝐲 𝐏𝐄𝐊𝐏𝐄𝐂 𝐏𝐨?
Helicobacter • 𝐌organella
Vibrio • 𝐏rovidencia
S. aureus • 𝐄. coli
S. pyogenes • 𝐊. oxytica
• 𝐏. vulgaris
✎ Rapid Urease Producers: 𝐓𝐏𝐔𝐍𝐂𝐇 • 𝐄. tarda
𝐓. mentagrophytes • 𝐂. koseri
𝐏PM (Proteus, Providencia, • 𝐏lesiomonas
Morganella)
𝐔reaplasma
VP (+): 𝐊𝐄𝐄𝐒𝐇
𝐍ocardia
• 𝐊lebsiella
𝐂. neoformans
• 𝐄nterobacter
𝐇. pylori
• 𝐄wingella
• 𝐒erratia
✎ Slow Urease Producers: 𝐂-𝐊𝐄𝐘𝐒
• 𝐇afnia
𝐂itrobacter
𝐊lebsiella
𝚃𝙸𝙿: If VP (+), automatic MR (-) and
𝐄. gergoviae vice versa
𝐘. enterocolitica
𝐒erratia
Citrate (+): 𝐏𝐫𝐨 𝐒𝐚 𝐂𝐇𝐄𝐄𝐊𝐒 👉3% H202:Staphylococci and
Micrococci
𝐏𝐫𝐨videncia
👉15% H202- Anaerobes
𝐒erratia
👉30% H202- Neisseria and
𝐂itrobacter Mycobacteria
𝐇afnia
𝐄wingella 👉N.gonorrhoeae:ferments (g)lucose
𝐄nterobacter 👉N.meningitidis: ferments glucose
and (m)altose
𝐊lebsiella
👉N.lactamica- ferments
𝐒almonella enteritidis glucose,maltose,(l)actose
👉Bull’s eye colonies in CIN: 👉C.tetani: spastic paralysis
Y.enterocolitica
👉C.botulinum: flaccid paralysis
👉Bull’s eye rash: B.burgdorferi
👉Bull’s neck- C.diphtheriae
👉Common pili:
attachment/adherence
👉Erythrasma:C minutissimum 👉Sex pili: Conjugation
👉Erysipelas:S pyogenes
👉Erysipeloid:E rhusiopathiae 📌TSI and LIA
•TSI
📌#1 NTM that cause TB in AIDS px: 👉Slant:Lactose/Sucrose fermentation
M.avium
👉Butt: Glucose Fermentation
📌#2 NTM that cause TB in AIDS px:
M.kansasii •LIA
👉Slant: Deamination
💡sl(A)nt:de(A)mination
Amount of H202 👉Butt: Decarboxylation
💡(B)utt:decar(B)oxylation
Ammonium cyanide/ almond-like
odor: 𝘾. 𝙫𝙞𝙤𝙡𝙖𝙘𝙚𝙪𝙢
Chocolae cake/burnt chocolate
odor: 𝙋𝙧𝙤𝙩𝙚𝙪𝙨
Buttery odor: 𝘽𝙚𝙩𝙖 𝙝𝙚𝙢𝙤𝙡𝙮𝙩𝙞𝙘 Common Congenital Infections:
𝙨𝙩𝙧𝙚𝙥. 𝐓𝐨𝐑𝐂𝐇𝐞𝐒
Freshly plowed grass: 𝙉𝙤𝙘𝙖𝙧𝙙𝙞𝙖 𝐓𝐨xoplasmosis
Putrid/burnt sugar: 𝙋𝙧𝙤𝙩𝙚𝙪𝙨 𝐑ubella (German Measles)
Old socks: 𝙎. 𝙖𝙪𝙧𝙚𝙪𝙨 𝐂ytomegalovirus (CMV)
𝐇𝐞rpes Simplex Virus (HSV) or HIV
Bleach odor: 𝙀𝙞𝙠𝙚𝙣𝙚𝙡𝙡𝙖 𝐒yphilis
𝙘𝙤𝙧𝙧𝙤𝙙𝙚𝙣𝙨, 𝙃. 𝙞𝙣𝙛𝙡𝙪𝙚𝙣𝙯𝙖𝙚
Musty/mushroom: 𝙋. 𝙢𝙪𝙡𝙩𝙤𝙘𝙞𝙙𝙖
𝐄𝐓𝐄𝐂: Cholera-like toxin (watery
Mousy odor: 𝙃. 𝙞𝙣𝙛𝙡𝙪𝙚𝙣𝙯𝙖𝙚, diarrhea; Traveler’s diarrhea)
𝙋𝙖𝙨𝙩𝙚𝙪𝙧𝙚𝙡𝙡𝙖
𝐄𝐈𝐄𝐂: Shigella-like infection (bloody
Horse stable odor: 𝘾. 𝙙𝙞𝙛𝙛𝙞𝙘𝙞𝙡𝙚 diarrhea)
Popcorn odor: 𝙉. 𝙖𝙣𝙞𝙢𝙖𝙡𝙤𝙧𝙞𝙨 𝐄𝐏𝐄𝐂: Infantile diarrhea
𝐄𝐀𝐄𝐂: Watery diarrhea in children &
AIDS px
𝐄𝐇𝐄𝐂 / 𝐒𝐓𝐄𝐂: Shiga-like toxin
(bloody diarrhea + HUS)
🐣 Gentamicin BAP - S. pneumoniae
Ammonia like odor: 𝙎.
🐣 Bacitracin CAP - H. influenzae
𝙢𝙖𝙡𝙩𝙤𝙥𝙝𝙞𝙡𝙖
🐣 Cystine Trypticase Agar - for
Fruity, grape-like, corn/tortilla-like
Neisseria; CONFIRMATORY
odor: 𝙋. 𝙖𝙚𝙧𝙪𝙜𝙞𝙣𝙤𝙨𝙖
🐣 Trypticase Soy Broth - Brucella
Apple/strawberry odor:
spp.
𝘼𝙡𝙘𝙖𝙡𝙞𝙜𝙚𝙣𝙚𝙨 𝙛𝙖𝙚𝙘𝙖𝙡𝙞𝙨
🐣 Alkaline Peptone Water -
Dirt like odor: 𝘽. 𝙘𝙚𝙥𝙖𝙘𝙞𝙖
Enrichment medium for Vibrioo
Leishmania donovani RFMoMa per LPF = 𝐌𝐮𝐒𝐞𝐜
🍪 Amastigote - diagnostic; contains • Mucus Thread, SEC
Leishman-Donovan bodies; GOLD
STANDARD *** 𝘙𝘍 𝘔𝘰 𝘔𝘢 = 𝘙𝘢 𝘳 𝘦 , 𝘍 𝘦 𝘸,
𝘔𝘰 𝘥 𝘦 𝘳 𝘢 𝘵 𝘦 , 𝘔𝘢 𝘯 𝘺
🍪 Visceral Leishmaniasis
🍪 Dumdum fever
RAAS > Angiotensin II: 𝐃𝐀-𝐂𝐄
🍪 Black fever
(I pronounce this like “daisy”)
🍪 Kala-azar
DA = causes vasoDilation of Afferent
arteriole
CE = causes vasoConstriction of
Efferent arteriole
Quad Screen: Markers for Down
Syndrome (Trisomy 21)
𝐇𝐈𝐠𝐡 levels:
CLINICAL MICROSCOPY
• H = beta Hcg
Manner of Reporting in Microscopic
Examination • I = Inhibin A
Average per HPF = 𝐑𝐎𝐖𝐑 Low levels:
• RBC, Oval Fat Bodies, WBC, RTE • AFP
Average per LPF = 𝐂𝐚𝐬𝐭𝐂𝐫𝐀𝐛𝐬 • Unconjugated estriol
• Casts, Abnormal Crystals high ang hi basta ganun HAHAHA
RFMoMa per HPF = 𝐓𝐓𝐁𝐚𝐘𝐚𝐍 📝 MICROSCOPIC QUANTIFICATION -
CM 📝
• Trichomonas, TEC, Bacteria, Yeast,
Normal Crystals Rare, Few, Moderate, Many "RFMoMa"
•RFMoMa/HPF
"𝐓𝐓𝐁𝐘𝐍" or TTBYaN 𝐑eservoir
-Trichomonas 𝐄xit portal (Portal of exit)
-Trans. Epi. Cell 𝐌ode of transmission
-Bacteria 𝐄ntry portal (Portal of entry)
-Yeast 𝐒usceptible host
-Normal Crystals
•RFMoMa/LPF
"𝐌𝐮𝐜𝐮𝐬𝐒𝐞𝐜𝐬"
-Mucus
-Squamous Epithelial CellS
•AVERAGE/HPF
"𝐑𝐎𝐖𝐑"
-RBC
-Oval fat bodies
-WBC
-RTE cells
•AVERAGE/LPF
"𝐂𝐚𝐬𝐭𝐂𝐫𝐀𝐛"
-Casts
-ABnormal CRystals
*CrAb = AbCr --binaligtad lang para
madali ma-remember 💗
𝐎𝐅 𝐈𝐍 𝐅𝐄𝐂𝐓𝐈𝐎 𝐍 : 𝗜
𝗦☣️
𝗠
𝗘
𝗥
𝐈nfectious agents
Not an obligate end cell:
Monocyte
HEMATOLOGY Most fragile blood cell:
Portland - 2 zeta, 2 gamma Gower 1 - 2 RBC
epsilon, 2 zeta Gower - 2 alpha, 2
epsilon Fetal - 2 alpha, 2 gamma A1 - 2
alpha, 2 beta A2 - 2 alpha, 2 delta
Acute myeloblastic leukemia without
Wiskott-Aldrich Syndrome > Triad maturation:
(Manifestations): 𝐖𝐞𝐚𝐫 𝐀 𝐓𝐈𝐄 𝐖iskott-
𝐀ldrich syndrome T = M0
Thrombocytopenia I =
Immunodeficiency E = Eczema Acute myeloblastic leukemia with
maturation:
VENIPUNCTURE > ORDER OF DRAW:
𝐒𝐭𝐨𝐩 𝐋𝐢𝐠𝐡𝐭 𝐢𝐬 𝐑𝐞𝐝, 𝐆𝐫𝐞𝐞𝐧 𝐋𝐢𝐠𝐡𝐭 𝐢𝐬 𝐆𝐨 M2
• 𝐒PS / Sterile (Blood Culture tube) •
𝐋ight blue top (Na Citrate) • 𝐑𝐞𝐝 top •
𝐆reen top (Heparin) • 𝐋avender top Acute promyelocytic leukemia
(EDTA) • 𝐆ray top associated with DIC:
M3
"snowplow" effect on a blood smear
must be examined using what
objective? Associated with endomitosis:
HPO Thrombocyte
Erythroid cell with 'wheel spoke' Also known as tissue thromboplastin
pattern of chromatine: (tissue factor):
Basophilic normoblast Factor III
Cell with a nucleus having
"checkerboard" appearance:
Also known as Fletcher factor:
Polychromatic normoblast
PK
Also known as Fritzgerald factor: Wintrobe tube length:
HMWK 115mm
Anemia causes: Effect of insufficient centrifugation
on hematocrit:
Decreased ESR
False increase
Low room temperature causes:
RBC index not affected by a defective
Increased ESR centrifuge used to determine Hct:
RDW
Most reliable criterion to differentiate
mature from immature cell:
It directly measures the variability in
Nuclear chromatin platelet size:
PDW
Also known as teardrop cell:
Dacrocyte Last stage in the erythroid series
capable of mitosis:
Polychromatic normoblast
Slide angle for blood smear
preparation if patient has
polycythemia:
15 degrees
Pathway that generates 2,3-DPG:
Rapport-Luebering
Most commonly used dilution for
WBC count: Glutamic acid on the 6th position of
beta chain is replaced by valine:
1:20
Hemoglobin S
Contains RNA and identified by This condition will most likely lead to
staining with new methylene blue or hypoxia
brilliant cresyl blue
Methemoglobinemia
Reticulocyte
Normal myeloid:erythroid ratio in
his coag factor is decreased in bone marrow
Hemophilia A
3:1
VIII
A medical technologist performed a
Process of replacing the active peripheral blood smear but it turned
marrow by adipocytes during out too thin. The medtech should:
development
Increase angleof spreader
Retrogression
Least stable coag factors?
Mechanism of spleen in removing
senescent RBCs in which cells are V & VIII
phagocytized with subsequent
degradation of cell organelles
Culling A 6-year old male patient accidentally
consumed lead-based paint. In
examining the PBS of the patient,
what will you observe?
This type of Hb migrates with Hb D
and Hb G on alkaline electrophoresis Basophilic stippling
but separates from them when citrate
agar (acidic pH) is used
Hgb S Which of the following coagulation
factors belonging to the prothrombin
group is not consumed during the
process of coagulation?
The enzyme reptilase is derived from
what species? II
Bothrops atrox
Blood:sodium citrate ratio for
coagulation studies
9:1 Giant platelets are seen in
Bernard-Soulier disease
Test(s) for Factor XIII
5M urea test These are cells that can produce
lymphokines and antibodies
Lymphocytes
In performing the Ivy method for
bleeding time, a BP cuff is used. It
should be inflated to a constant
pressure of In the FAB classification of AML, M2
is also known as:
40mmHg
AML w/ maturation
A pregnant woman is experiencing
folic acid deficiency, what will be the The primary site of hematopoiesis in
morphology of her RBCs as seen in the 3rd month of gestation
the PBS?
Liver
Macrocytosis
Match the stage of ESR with its
Characteristic of beta thalassemia correct duration
Increased Hgb A2 Rapid Settling - 40 mins
Clot dissolution (Fibrinolysis) is RBC crystal seen in the cytoplasm
made possible by: that is described as “gold bar” or
“Washington monument”
Fibrin
Hb C crystal
A medical technologist performed a
CBC on a patient with normal WBC
and Diff. count. Arrange the different
Which of the following is not types of WBCs in descending order
included in primary hemostasis? as seen in the patient’s result
Stabilization of fibrin N-L-M-E–B
Hairy cells are √ Mesoblastic phase / yolk sac -
PRIMITIVE; 19th day of gestation - Only
B lymphocytes the RBC lineage is present
√Hepatic phase - 5th-7th week of gestation -
Hb F - MOST predominant hemoglobin -
A medtech performed a cytochemical ALL lineages are present (such as Wbc, rbc,
stain, leukocytes demonstrated a etc.) - LIVER is the major site of
positive reaction with tartrate- hematopoiesis during this phase
resistant acid phosphatase (TRAP).
This is seen in what condition? √ Medullary / Myeloid phase - third
trimester (4th to 5th month of gestation) -
Hairy cell leukemia Hb A - most predominant hemoglobin in
ADULTS
Hb Gower-2 is composed of
2 alpha +2 epsilon chains
SPLEEN
- graveyard of RBCs; storage site of
Heme synthesis starts in what Blood cells
structure of erythrocyte precursors
- where CULLING and PITTING
Mitochondria process occur
- LARGEST lymphoid organ
Right angle light scatter in flow
NOTE:
cytometry is used to measure what?
Culling - removal of senescent (OLD)
Cytoplasm granularity
RBC
Cabot ring is an erythrocyte inclusion
Pitting - removal of RBC inlusions
seen in megaloblastic anemia and
myelodysplastic syndromes
appearing as rings or figures of eight.
What is its composition? Hypersplenism/Splenomegaly -
PANCYTOPENIA
Mitotic spindle remnant
Asplenism/Splenectomy -
PANCYTOSIS
Who described platelets as “petite
plaques”
NOTE:
Wright
PANCYTOSIS - ↑ RBCs, ↑ WBCs, ↑
Platelets
PANCYTOPENIA - ↓ RBCs, ↓ WBCs, ↓ MEGALOBLASTIC ANEMIA
Platelets
📌Due to Vitamin Deficiency:
•Vitamin B12 deficiency
Old senescent RBCs - rigid and
spherocytic •Folate Deficiency
RBCs that are <120 days old =
DEFORMABLE
📌Other causes:
BITE cells - formed through the
process of PITTING •C-ongenital dyserythropoietic
anemia
— Ex.: G6PD - has denatured
Hemoglobin •R-everse transcriptase inhibitors
— Heinz bodies - denatured Hgb; •A-cute erythroid leukemia
should go through PITTING once it
goes to the spleen •M-yelodysplastic syndrome
To remember:CRAM🤯
GLYCOGEN STORAGE DSE
1 - Von Gierke (Viagra) 📌If screening tests reveals:
2 - Pompe (Pill)
•Oval macrocytes (MCV:100-150fL;
3 - Cori-Forbes (Causes)
commonly:greater than 120fL)
4 - Andersen (A)
•Pancytopenia
5 - Mc Ardle (Muscle)
•Reticulocytopenia
6 - Hers (Hardening)
•Hypersegmented neutrophils
7 - Tarui (Tarugo)
•Increased total and indirect bilirubin
8 - Hug/Ohtani (Huoy)
•Increased lactate dehydrogenase
9 - Bresolin (Bastos)
10 - Tonin ('To)
—>proceed to confirmatory testing
11 - Fanconi-Bickel (Fvcc boi)
💉EDTA
12 - Kreuder (Kasi)
•Mode of action: Chelates Calcium
•MOST PREFERRED AC in Factor VII
HEMATOLOGY
•Dry Form (Na2 and K2 EDTA); Liquid
form (K3 EDTA) Last factor to be depressed in
Vitamin K deficiency
•Na2 salt- VERSENE
Factor X
-how to remember? ver/sene has 2
syllables
•K3 EDTA salt-SEQUESTRENE Which of the following factors is NOT
present in BaSO4 adsorbed plasma?
-how to remember? sequesTHREEne
Factor II
Which coagulation factor is present
in the highest concentration in Which of the following factors
plasma? typically shows an increase in liver
disease?
Factor I
Factor VIII
Which of the following participates
ONLY in the extrinsic pathway? Which of the following factor
deficiencies is associated with either
Factor VII NO bleeding or only a MINOR
bleeding tendency, even after trauma
or surgery?
The Activated partial thromboplastin Factor XIII
time is NOT affected by the
deficiency of which factor?
Factor VII
Which of the following disease would
you most likely find an abnormal
Prothrombin time is NOT affected by prothrombin time?
a deficiency of:
DIC
Factor VIII
✨ Color coded needle ✨
Which of the following is vitamin K
dependent? 18gauge - Pink (remember: 18th bday
debut; pink motif)
IgG Antibodies: 𝐭𝐡𝐞 𝐑𝐢𝐜𝐡 𝐃𝐚𝐫𝐢𝐧𝐠 𝐊𝐢𝐝
𝐜𝐚𝐧 𝐊𝐢𝐥𝐥, 𝐒𝐡𝐢𝐭! Rh Duffy Kidd Kell Ss
21gauge - Green (remember: 21 guns
by GREEN DAY) James 𝐑𝐈𝐃 𝐅𝐀𝐊 𝐌𝐄
RID = Radial Immunodiffusion
22gauge - Bl’A’ck FAK = Fahey and McKelvey • Kinetic
23gauge - Bl’U’e/Turquoise ME = Mancini • Endpoint
(Remember: mas una ang “A” kesa
“U” 🥲)
🩸MINOR BLOOD GROUP🩸
📌LUTHERAN
• Luteran
• Chromosome 19
• Bind to LAMININ in sickle cell
• Anti-Lua: LE
• Anti-Lub: Jaundice
IMMUNOSEROLOGY AND BLOOD 📌DIEGO
BANKING
• Dia: Mongolian Ancestry
• Band 3 or AE1
CYTOKINES: 𝐇𝐎𝐓 𝐓-𝐁𝐨𝐧𝐞 𝐬𝐭𝐄𝐀𝐊
• ASO (Acanthocyte, Spherocyte,
IL-1 = Fever (Hot) Ovalocyte)
IL-2 = stimulates T-cells 📌CARTWRIGHT (Yt)
IL-3 = stimulates Bone marrow • Glycosylphosphatidylinositol (GPI)
IL-4 = stimulates IgE production • Acetylcholinesterase
IL-5 = stimulates IgA production
IL-6 = stimulates aKute-phase protein 📌XG
production
• Female (89%) Male (66%)
• Short arm of X chromosome
• CD99 or CD19 📌CROMER
• DAF or CD55
📌SCIANNA
• Chromosome 1 📌KNOPS
• ERMAP • CR1 or CD35
• SC2: Mannonite population • SLE & CAD
📌DOMBROCK • Knops null: HELGESON
• Chromosome 12
• ART-4 (Mono-ADP 📌INDIAN
Ribosyltransferase 4)
• CD44
📌COLTON
📌OK
• Aquaphorin 1
• CD147
📌GIL
📌RAPH
• Aquaphorin 3
• MER2
• CD151
📌CHIDO/RHODGERS
• Not intrinsic to RBC membrane
📌JMH
• C4 conplement
• CDW108 or Somaphorin 7A
• C4a: carrier RODGERS
•C4b: carrier CHIDO
📌RHAG
📌GERBICH
• Newest Blood Group System
• Glycophorin C and D
• Leach, Gerbich KELL
HISTOPATH AND MEDTECH LAWS &
ETHICS
RA 11223- Universal Health Care Act
RA 9288- Newborn Screening Act RA
7277 - Magna Carta for Disabled
Persons
PRC
- Chairman: Atty. Charito A. Zamora
- 2 Commissioners: Jose Y. Cueto, Jr.,
Erwin Enad
MT Board
-Chairman/Head: Dr. Marilyn Cabal-
Barza
- Member: Ms. Leila Lany Florento,
Other is vacant
