<—eTION BANK — question ai = 70! one eral Pathology 9 Gone Haematol aa PATHOLOGY lita tions ¢ gues pot Meihint Larter 1 ores he ory en — TN “NECROSIS =e ; 1. Role of free radicles in cell injury @ | ap (May 2007, Oct. 2004) 2. Definition and types of necrosis, (Apr. 91,93), 49 49 as 3. Coagulative necrosis (Oct. 88)! 40 Oo 2 4, Caseous necrosis (apr. 84)| 41 | 49S 5. Fat necrosis (apr 88}| 41 50D 6. Fibrinoid necrosis (Oct.97)) 41 51 7. Apoptosis ea (Feb. 2019, Jan. 2015, July. 2015, Oct. 2002) ne Autopsy (Jen. 2012) - 2 -- 5. Cosnstrasting features of apoptosis and necrosis, 4042, 59° 3 (Jan. 2014, Mar. 2010) - 10, Name 4 morphologic changes (Cytoplastie & nuclearlin| 40 Necrotic cell, (an, 2013) 1. a SSSS—S LUst any four types of nectosis with one example each. 40 (dan, 2016) Types Fee te og 40 of necrois with examples. (Aug. 2021 (KNR)m EC (ET GANGRENE a Short and Very Short Questions : TT 13. Gangrene (Oct. 97, 2008) | x a 14, Dry gangrene (4pr. 93)) 111 gp 7 Dry gangrene 15. Wet gangrene (Oct. 89)| 111 =a, | 16. Gas gangrene (dan. 2011, Oct. 82] Tit | sep Pa Peer eka aee Ce Short and Very Short Questions : 1. Hyperplasia Zan. 2015, Oct 89, Apr. 84)| 59 | 36 |B 2. Hypertrophy (Oct. 84, 86)| 57 | 36 | a 3. Atrophy (Apr 2005, 85, Oct. 88), 59 | 35 | 8 4, Metaplasia. (March. 2021 (NTR), Feb. 2019, May 2006] 61 | 38 | 4 Oct, 2001, Apr. 92, 90) | 5. Brown atrophy of heart 59 67 a 6. Dysplasia (Apr. 2005, 99, Oct. 2002) 270, 454 38 | 197 7. Steatosis (Oct. 87)| 62 | 62 | 8. Staining fat in tissues (Apr 83, 87)| 62 | 62 | 4 9. Body pigments and their importance (Apr 89)| 64 | 64 [#4 10. Exogenous pigments jong} 4 | 8 |® 11. Lipofuscin pigments (pr 93) 64 1 | a 12, Melanin pi a nin pigments Toa oa] 64 64 [% 13. Alkaptonuria 6 26 (Oct, 94)| 64 | 14. Pathologie calcification a |S (Sep. 03, Oct. 93)| 65 | 15. Dystrophic caleification |__| 3 (Apr. 90, 92, Oct.99)| 65 | 4 | — 16. Metastatic calcification 55 8 (Apr. 97)| 66ebbing | Hanbun | R Rayo (Oct. 92) 64 | 47) 40 (May 2007) free 120 | 59 | 287 | 244 fof 0 ” Finous Inflammation PE a NET jor questions : 1, Desrbe the signs of acute inflammation and discuss the yascular and cellular events In acute inflammation. (Feb, 2019, Apr. 91) 2. Define inflammation describe briefly the role of chemical smediators (Apr. 96, 97, 98) ee rails: (July. 2014) | 52 | 44 | 19 (Wan, 2015)| 41 | 88 | 67 7 | 70 | 51 85 77° (49,59 4. Define and classify granuloma, Discuss the mode of formation of tubercle (Oct. 99) (or) Define and classify granulomatous inflammation. Discuss the gross and microscopic changes of tuberculosis of lymph sland (Apr. 92) Sion and Very Short Questions : 100 | 91 [69,70 512 100 | 135 |69,70 513 (Feb. 2019, Apr. 83, 2009) sp e20) ao) 1. Signs of inflammation 2 Vascular phenomenon in inflammation owen] 76 | 7 |S 3. Cardinal sign of acute inflammation taoraooms [76 | 7 | © 79 75 55 ‘Apr. 90, 99, 2010, 4 Chemotaxis 9, 01, 2008) May 06, Oct. 90, 96, 95 Pegocyons “Feb D000 (KN, Aug 2019. 80 | 75 | 56 July. 2015, 2013, Oct. 2002, 98) | Acute phase reactant. (Aug. 2021 (KNR) 85 si | 72Short mation 6. Chemical mediators of inflammation | os oat 87) 1 11, Giant cells: 7. Lymphokines (Aug. 2021 (NTR) 88) 7g 8. Lipoxin | ai (Oct. 84)) 99 | By fee ds ee SHES and Very Short Questions : a (Jan. ee ee eEEnnnee (Oct. 88)! 88) 7g a @ Ep ee Be eee reid 9, Granulomatous inflammation (et. 90), 100) 9] ir 208, Sep 08, Oct. 97) 100 | G1 0. Granuloma Thor 2005, Sep. 08, Oct. 97)) 100 | oT Senators ne ae “May 2006, Apr. 91, 2003, 2008, Oct. 01) 100 | 86 ay (Aug. 2009), 371 | 98 12, Primary complex. | (0c. 85) 93 | 88 a 13. Membranous inflammation 1 1 16. Role of complement in inflammation. (March. 2010)| 90 | 79 Protein derived mediators of acute inflammation | 85 | 81) 2 (Feb, 2010 (KNR), Jan. 2013) (July. 2017) 90 | 83 | 63 4. Chemokines. 5. J | PRE CFT Essay 1 2. ) Short and Very Short Questions : Questions : Define repair. Discuss the mechanism of healing in a surgical wound. Mention the causes of delay in wound | healing (Oct. 94) | 103 | 112 79 Describe the healing of a fracture. Enumerate the causes of] 1172 | 118 | 84 nonunion of fractures (July, 2013, Apr. 99) SCE eee eee eee) EIe [27 2 1, Growth factors (Jan, 2014, 2011, Oct. 96)| 106 | 217 | 2. Granulation tissue (Oct. 96)| 105 | 113 | 7 3. Healing ofa wound pen goia- Garay lealing of a wound (Feb, 2018, Oct. 62)| 108 | 116 | ” 4. Healing by secondary intention ] 110 | 116 (® (Oct. 2008, May. 2007, Apr. 96) |we Robbing | Harshmohan |R. Naya jors that influence wound healing. (Oct. 2004, 2001)! 110 | 115 | 81 joe | 5 Ffeaing of fracture (Apr. 2005, 2003) | 1172 | 118 | 834 ‘ | Fag of fist intension (July. 2015, Aug. 2009) | 108 | 116 | 79 1 as TEE Dao SET ] 1 scum i +) fine edema, Discuss its etiopathogenesis ‘apr 93)| 115 | 165 | 112 (or) bene & classify edema. Discuss about nutritional edema (Apr. 95) 1. Destibe briefly the pathogenesis, pathology and fate of 125 | 183 | 120, thrombus (ct. 96) 122 4. Discuss the etiology, pathogenesis and complications of 134 | 178 | 134 shock (Oct. 93) 4. N85 year old lady was brought to the emergency room115/ 180 136 unconscious. her blood pressure was very low, pulse was weak and rapid. Her skin was warm and flushed. Her blood culture revealed growth of Gram positive bacteria. (a) Whatis the possible diagnosis ? (®) Desctibe the pathogenesis of this condition. (©) Describe the stages of this disorder. 5 115 | 180 | 136 450-- year old female, known diabetic with irregular treatment Presented in semiconscious state with high Stade fever, cold, clammy extremitic. On examination ‘tensive cellulitis of right lower limb seen. Her BP was 70/50 mm Hg. Heart rate 102 beats per minute with weak Pld pulse, temp 103°F. (Aug. 2021 (KNR) 6 ) What is your diagnosis? Justify, i ) Discuss the stages of this condition. ( ") Witte Etiopathogenesls of this condition. iEssay Questions : 6. a 55 year old lady was brought to the emergency room unconsciou with history of road accident. She ustained multiple injuries, fractures of femur and tibia. These fractures after admission. However are stabilized at urgery soon 2 days after admission, she suddenly becomes dyspneic and developed tachypnea and tachycardia,irritability restlessness and it is progressed to delirium, coma and death on 7 day. (Mar. 2021 (NTR) | (a) What i the provisional diagnosis. | (b) Discuss the pathogenesis ofthe lesion. Describe microscopic picture of the lungs in the above CONT COMPANION Gp — Re ain 131 7 (c) condition. (a) How frozen sections of the lung tissue help in final | diagnosis at autopsy and mention various stains specific | forit. Short and Very Short Questions : Pathogenesis of edema (Aug, 2019, Oct. 2002) | 115 | 165 | 13 115 | 166 43 2. Differences between transudate and exudate (Apr. 2009, 99) | (Apr. 2005, 90)| 115 | 168 8 Renal edema Non pitting edema (Oct. 89), 115 | 165 2 Pulmonary edema (Feb. 2020 (KNR), Apr. 89)| 117 | 169 us Cardiac oedema (March. 2021 (NTR), Oct. 2008, | 117 | 1698 May. 2008, 2007, Apr. 87 Tis 1175 8 Pathology of venous congestion (Oct. 86) aeu fo ng (Apr. 98, 92)| 133 | 176 Heart failure cell (Apr. 93) rare 31 pr. | amg Lie (Apr. 98, Oct. 94)| 131 Siar |! Pl (Oct. 92) A Tonbow jf (Apr. 91, Oct, 90)/ 125. | 1805 | tte | astra nn 5 saathrombosts (Oct. 87, Apr 89) | 128 | 187 | 20 / amon i 205 . | 129 F187 Paes Aug. 2010, May, 2006, Oct, 2011) : xeavoonbolom Av 2008) 189 | 127 % am « A 98, 04.98) | 188. | 127, yy Pulnonary embolism (Apr. 92) 189 | 127 18 Systemic thrombo embolism. (Jan, 2012) | 131 189 | 128 8 Fat embolism (March, 2021 (NTR), Jan. 2014, | 131 190 | 129 Oct. 94, 92, Apr. 98, 96) 2 Airembolism (July. 2015, Apr. 2005, Oct. 2002, 99, 98, 94) 132 191 130 1 Infarct (Apr. 99) | 133 193 132 2 Types of infarction and description (Oct. 88) | 133 194 | 132 inend Very Short Questions : | B_Chssiication of shock (apr 69) | 134 | 178 | 184 4% Mechanism of shock in burns (Oct. 86) | 135 180 | 134 & Pathogenesis of septic shock Gduly. 2017, Oct. 2004) | 135 | 180 | 136 15 Deumpensated chockimeversible shock (Apr 2003) | 185 182 | 140 2. Shock tung (apr 2008) | 133 | 182 | 134 B Septic shock (Feb. 2020 (KNR), 2018, Moy 2006) | 135 | 180 | 136 4 Amniotic Nuld embolism (May 2006) | 132 | 192 | 131 3. Hypovolaemie Shock (duly 2011) | 134 | 178 | 134 1 Viral thrombus (Aug 2009) | 126 [100,101] 122 2 Pilebothrombouis Ven. 2011) | 126 | 189 | 125 Enumerate four causes of Disseminated Intravascular 130 | 353 | 377 " Corgulation (DIC) (Jon. 2016) Pathogenesis of type | hypersensitivity reaction. | 205 | 140 ] 147 (Feb. 2019, July. 2015) —a pe N Abe PASTS TT Short Question: Gwolving sexchromosomes Name two cytogenic disorders involv ae and two involving autosomes. Robbins My | ae 163 | dg i Hy Thromosomal mutations (apr Se. 02) [168 ar Inborn errors of metabolism (Oct. 87)| 154 | 2937 Vongierke’s disease (Oct. 92)) 160 | 293 > Down syndrome (Trisomy 21) (Aug. 2021 (KNR)| 166 | 289) | (Aug. 2019, Jan. 2013, Sep. 2003, Oct. 2008, 99, 97) | Sex chromosomal disorders (Apr. 96)| 170 | 289 | a9 Sex chromatin (Oct. 2004) 170 | 288 2g Barrbody (apr. 2008, 2009 Oct. 02, Jan. 2012)| 170 | 288 | 25 Kline felter syndrome (Mar. 2021 (NTR),| 170 | 289 | 253 Aug. 2019,July. 2015, 2011, Apr. 98, 97, 91, Oct. 2001) Turner's syndrome 171 | 289 | 26 (July. 2013, Apr. 2003, 2005, 2009) Physical & chemical nature of amyloid. (Wan. 2012)| 256 | 152 | Il X-Linked dominant and X-linked recessive disorder. 255 | 292 | 28 Short and Very Short Questions : 1 Ti lymphocyte Tan bay 194 ice 2. B-lymphocyte Daren ss aH 7 3. Anaphylaxis a 77) TT 4. Systemic lu (once) | Pus erythematosus fou aay] 221 | 147 160 ct. 5. Kidney lesions in SLE (Aaa ISTO. i 0 rie , Oct. 2004) 6. LE cell phenomenon =e 18 7. Antinuclear a (Oct. 2008, 97)| 221 Le ntibody ai (May. 2007)| 225ss ET sions? EE suon ues aie ya aa ate : Sparen synrone (Oct. 96) | 229 16 65 famunogiobulins (Oct 93) 201 404 | 144, 201 | 404 (Aug. 2021 (KNR) | 205 140 px AMYLOIDOSIS. 1 yer actions of amyloidosis 260 157. 185 yp Seining B Source and chemical nature ‘of amyloid Feb. 2020 (KNR), | 260 152 181 Aug, 2019, Apr. 2008, 85, Oct. 86) 14. Nature of amyloid Wan. 2014, Apr. 2008) | 260 152 | 185 1. Cardaceous spleen. (Aug 2009) | 264 | 159 | 183 16 Chsifcation of amyloid with example (Oct 62)| 261 | 153 | 183 11. Primary amyloidosis (Apr 2010, 88) 261 | 154 | 183 18 Lesions in secondary amyloidosis (Oct 90) | 262 | 154 | 184 13, Amyloidosis of spleen/Sagospleen pea | 159" | 185 (Oct, 2001, 97, July 2011) | 2. Sago spleen. (Aug. 2009, Oct 2001, 97) 264 | 159 | 185 21 Pathogenesis of amyloidosis (Jan, 2013, March. za) 260 | 156 | 182 % Mention four examples of antibody mediated type-II 209 | 140 | 150 Hypersensitivity reaction. (July. 2017) | | | 2 Stains used to demontvate Amyloid (Mar. 2021 NTR) | 260 | 157 | 185 (Aug. 2021 KNR) t ™ " Questions; | | | Defi ie neoplasia, Describe in detail about the histological | 268 {190,202) 187, featur Paar various modes if spread of malignant | 206 | 223 (Oct. 90) |« FALCONS SOON a m | | ty 2. Detine neoplasia Discus rely abot chemi 268 sea . carcnogens a (Oct, 92} (or) Desert (May 2007)) 270 ap 1. Anaplasa pl 2 ifrentate between benign and malignant tumors 210) ay eS (Feb. 2018, Jon. 2016, 003, 2008, 2009, Oct. 2001) ibe in detall about carcinogens pn 2 3 Characters of malignant ces mm | a (July. 2013, Ap. 90, 88) 4, Metastasis (hp 2003, Moy 2006, Oe. 99)] 273 | 206 |g” ‘ug 2019, Jon. 2014, July 2011,) 274 | 206 | 198 (ct, 2004, Apr. 98, 97, 96) | (ct, 2008, 2004)/ 274 | 206 | 18 (Oct. 85)} 272 | 212 5, Spread of tumors 6, Modes of spread of malignant tumours. 1. Preencerous condons mH 8 Chemialcarinogenes (Ot. 69, Apr. 88, Aug 2009)| 282 | 227 | 2 Wan, 2013)| 282 230 | 8. (apr 85)) 323 | 280 | 29 | 9, Physical carcinogenesis. 10, Radon injury 11, Biological carcnogensvirl carcinogenesis, 282 | 232 (Oct 93, pr. 2010) 12 Oncovituses (on. 200, Sep 03, Oc. 96)| 324 | 232 os 13, Paraneoplasic syndromes (Feb, 2019,| 329 | 239 e Moy 2007, Oct, 2002, Jn. 2011) 4 Laboratory findings in neoplasia (Fe, 2019, Oct 66)| 331 | 242 BE 15, Tamourmaes (e200 (RNR) uy 205, Apr 008)| 588 rs 16. Basle arcnona rie | ot | 88 17, Microbial carcinogenesis adel Eee (March 2070) 324 | 232ccopgEsTiON BANK. eae git estions + pss? Y” es Fol metastae (Aug. 2021 (NR) ee Ta cogene. (Mar, 2021 (NTR) sear old beggar is admitted with skin patches and 103 i 374 | 103 | ea ules on the face. Skin patches are hypoesthetic, Few = ‘on both feet are amputated partly, (July. 2017) ig) Whatis the possible diagnosis ? How will you make the diagnosis ? fb) Chssify the disease. | (¢). What special stains will you do on the biopsy to make | | the diagnosis ? {g)_ Discuss the mode of transmission of the disease. | gutand Very Short Questions : | Pimary complex (Aug. 2019, July 2011,| 371 | 98 | 513 May. 2006, Sept. 2003Apr. 97, 98) | | 1 1 2 Ghon’s focus (Jan. 2015, 2013, Oct. 2002) | 371 | 98 | 513 | Pathology of secondary tuberculosis (Oct. 89) | 370 | 98 | 512 | (Oc. 87)| 370 | 98 | 516 + Lymphatic reaction of tuberculosis infection 5 Miliary tuberculosis (Aug. 2010, Apr. 93) | 373 | 100 ee ee ee § Typhoid 1338 | 595 | 564 ee "ele of selection & integrins Involved in the inflammatory 88. 74 |54,55 Fesponse (Jan, 2012) © Comma 516 (Oct. 2004, 92) | 376 | 108 | 92 a - (eee ee eee oy at Pheer syphilis (Oct. 90)| 376 | 108 | 92 Aetoomycoses 4 (Aug. 2010, Oct. 2002) | 368 | 109 | 100 Nberuloid ie a Ge ee 9 | 374 | 105 | 86 {—__}__ Prom a: 'sleprosy (Jan, 2076, July 2013, Apr 2003 | 374 | 105 | 86 | | | Oct. 2008, 2001, May. 2007) \ | avj 18. Lepr rection Sand tukberculod | 3747 105 e beneven lepromat (aug. 2021 (KNR) 88 Ta re 5 (apr 2010, 2008, 90) = | 256 0p (ape 2009, 2008, Oct. 2004, 82) | Kobe mycetoma. (March. 200) - | 109 100 | TO Short and Very Short Quest od by a chemical poison (Apr S6)| 407 | 268 | 223 Ine (apr 85)| 428 | 273 | 2 (Oct. 86)/ 428 | 273 - | 276 (et feat bite w Protein - energy malnutrition (apr 98)| 434 (Oct. 86)| 434 | 276 | 264 wo o Pathology of vit. A deficiency vit A deficiency disorders | 437 | 278 | 28 | | > (Apr. 2003, 2008) 7. Lesions of Viamin A deficiency Jon. 2014, Apr 2008)| 437 | 278 28 8 A deli i : in A deficiency disorders. (aug. 2010)/ 437 | 278 a Keratomalacia 43; . feratomalacia (Oct. 85)| 437 | 278 Rickets ws (Oct. 2008, 98, apr. 90)| 440 | 279 3 kel y “4 celetal changes in Rickets. (Wan. 2012)| 441 | 2 : eens 2212 12. Osteomalaca ‘oneal ao | 2st |” . | a a ud‘short Questions = oe yvery Matias Marakmohan Nayak sacogealteatores of ber -beri Apr 87.On1 64) | 443) 28S O72 ‘ foe oa ea lezeselzre : aoeC 84 BBA BT Pegs tt fo (apr. 84) | 442 | 282 | 270 Sais (Apr 86)| 444 | 274 | 265 ig. Consequences of vitamin A deficiency disease. (Apr 2009) | 437 | 278 | 268 PASS ae TT Very Questions = | sort 1. inborn errors of metabolism (Oct. 87) | 464 | 293 | — Neuroblastoma (Apr. 90) | 477 841 818 ; | 3. Wilm’s tumor (Oct. 2008, 97) | 480 727 709 (EEE HAEMATOLOGY RE ALS ees es Essay Questions : | | 1. Child with mangoloid face, small stature, mild jaundice, 645 | 335 | 311 splenomegaly failure to thrive admitted with diarrhea and recurrent fever. Mention various investigations with findings | to make a final diagnosis (Oct, 2001) 2 40 years old lady come with H/O recurrent bleeding from | 663 | 309 | 293 with pile complaints of weakness and tiedness. Mention various investigations to make a final diagnosis. | (Oct. 2002) | ‘55 year old female presented with bleeding per vaginum | 666 | 309 | 293 and white discharge. P/v examination revealed unhealthy | | indurated and ulcerated cervix. (Apr. 2005) (2) What is the probable diagnosis ? | \ () What laboratory test will confirm the diagnosis ? (©) What is the histopathology of the diseases ? ——_ettbehimopatnology ofthe demses? } tN a4,25 years old female with the H/O 4 months amenorthoea glossitis. Discuss complaining of mild jaundice, anemia and the causes and investigation to come to a diagnosis (Apr. 2003) ith weakness, fatigue and | 655 | 309 yp 5, 40 years old male presente dyspnoea, having spoon shaped nails complaints of recurrent bleeding piles. Hb is 2.5 gms. (Oct. 2008) (a) Whatis the provisional diagnosis ? (b) What blood investigations should be done to confirm the diagnosis ? What is the test to be done on the bone (o) marrow smear ?) 6, Ammale c) .d presented with recurrent painful haemarthrosis 668 | 351 3H and haematomas. History of bleeding in male relatives on the matemals side of the family was available. (Apr: 2008) | (a) Whatis the probable diagnosis ? (b) _Deseribe the inheritance of the disease ? | (c) Describe the lab diagnosis of the disease ? (@) Mention the complications following the therapy? = || 7. A2 year old child presented with fatigue, fever, epistaxis, { 51 ] 406 3 bleeding, gums and bone pain. On examination generalized lymphadenopathy and hepatosplenomegaly was noted. | Total leucocyte count was 15,000/ul. (May. 2007) | (2) Whatis the probable diagnosis ? (b) Describe the cytogenetics of the disease, | (c) Describe the peripheral blood smear and bone marrow findings of the same. | (d) Describe the prognostic factors of the disease. 5 | 317 jo irs | 8. 35 years old female presented with anaemia, glossitis and | 65: neurological manifestations (Apr. 2009) (a) What s your provisional diagnosis ? | (b) uy are the laboratory investigations you do in this | case’ (c) How do you confirm the diagnosis ? ee(Feb. 2020 (KNR). Aug 2009 2019, Feb. 2019) Whats the provisional diagnosis ? Describe the blood and bone marrow picture of the abovecase. Discuss the prognosis of this disease a) “Si 730 year old pregnant lady who cherishes to eat food 651 3i7 repared by boiling, steaming and frying presented with zraemia, glossitis, mild icterus history of diarrhoea, loss of appetite and lack of wellbeing no evidence of nervous gsiem anifestations. Her serum Homocysteine (HCYS) levels are levated but no Methylmalonic acid (MMA) Levels (Mer. 2010) (2) Whatis the provisional diagnosis ? |b) Describe the peripheral blood and bone marrow picture (c) Discuss the special test in diagnosos. 302 11 Acute lymphoblastic leukemia. (Jan. 2014) 594 392 336 12 One year old child is admitted with increasing pallor since | 651 | 332 the age of 2 months. On examination there is pallor and | hepatosplenomegely. Hb - 7.2 gm % ; TLC and DLC are ‘within normal limits. Platelets are normal. (dan. 2016) (2) What is the probable diagnosis? | (0) How do you classify the disease group ? (cl What is the blood picture in this disease ? (4) Give the clinical picture of the disease 4.48 year old male presented with pallor and easy 651 | 317 ‘atgebility. He complains of a sore tongue and tingling in | hands and feet. His haemoglobin level was 9 gms/dl. He | | i history of undergoing partial gastrectomy 3 years ag0 | (ot gastric ulcer. | 311 299ssay Questions : vo peripheral blood picture and bone patient thort and Vers Short Questions = 1 Pegeloaye Retculocytossendeauses. —SS=«):S«3B SQ Won. 2014, Oct. 82) 2 2017. Oc. 82) 637-324 3 (July. 2017. Apr. 90), 637 | 324 | 3% 4 (July. 2017, Apr. 86) 637 324.3% 5. (Apr 85), 638 | 329 6 (Apr 2008), 641 332 MT 7 (Apr. 99), 642 | 332 316 a (Oc. 84), 642 | 332 316 9 (apr. 85)| 655 | Sil | 2% 10 emia (Oc. 87), 644 | 335 Stl 11. Paroxysmal noctumal hemoglobinuria (PNH) (Oct 65) 648 | 328 | 52 12 heral smear and bone marrow picture of megaloblastic 651 | 320 300 a (March. 2021 (NTR), Jan. 2011. Oct. 99) | 13. What is the blood picture in Vit B12 deficiency anemia? | 651 | 320 00 (Jan. 2016) | | 14. Megaloblast (Mey 2007, Apr 87), 651 | 37 15. Peripheral smear and bone marrow picture in ron | 5 1 313 | 2 deficiency anemia (Jan. 2015, Oct. 99) | | | 16. Aplastic anemia (May. 2007, 2006, Apr 98.92), 659 | 340 | 3 17. Blood and bone marrow finding in aplasti anemia. | 659 | 340 | 3 (Jan, 2013) |ave wt" @ thrombocytopenia (May 2007) | 664 r Se _DUESTION BANK, ge py Short Questions : j Hurshohan |. Reyok [349 [371 ig emu Tiythroid ratio (M.E. ratio) (Ocz 2004) | ~~] 358-1 iyeloid 8 ES ae, (Oct. 93) | 664 | wy Fomos 349 [371 ‘idiopathic thrombocytopenic purpura (ITP) | 664 | 349 | 371 a. (Aug. 2021 (KNR)(March. 2021 (NTR), Feb. 2020 (KNR), Aug. 2019, Apr. 86 2 Wonwillebrand disease (July, 2017, Jan. 2015, 2012) | 668 | 352 | 376 | 13. Heemophilla (July. 2017, Sept. 2003, Oct. 98) | 668 | 351 | 374 14. Disseminated intravascular coagulation (DIC) 669 | 353 | 377 Sideroblastic anemia (Aug. 2019, Apr. 97) | — 314 | 324 8 (Jan, 2014) ~ 303 _ 1. Stain for regiculocyte Es ly Questions 1. Gassifly Hodgekin’s disease and describe the pathologic | 611 | 349 | 360 features (Oct. 99) Sintend Very Short Questions : 1. Leukopenia (Apr. 83) | 586 362 | 328 2. Agranulocytosis (Neutropenia) ‘Apr. 91) | 586 | 362 | 329 3. Leukemoid reaction (Apr. 2005, 98, Oct. 2002) 587 367 | 329 § Vial igmphadenopathy (Oct. 68)| 588 | 364 | 332 5. Classification of leukemia (Oct, 86)| 594 | 368 | 333 6 ae malignant tumors of lymphnodes and describe 594 | 368 | 356, 'stology of any one of them (Oct. 82) 360 7 Non Hodgekin’siymphoma ‘Apr 86) | 597 | 395 | 356 596 | 392 | 336 Pe “pheral smear in acute iymphoblastic leukemia (July. 2017, Oct. 89) ‘and Very Short Questions : ] Min lhe | ic lymphoblastic leukemia | 5077 Nn 9. Peripheral smear in chronic 7 ae (Apr. 96) Ms 0. Bone marrow in multiple myeloma (Feb. 2019, Apr. 94. 91)) 60g | ae 7 LL. Lab diagnosis of multiple myeloma (Oct. 90) [508 ae | 12, Hodgekin’s disease na Wuly. 2013, Oct. 92, 93, 2002, Apr. 93) 13. Reed stemberg cell 612 | 400 ae (Apr. 2008, 84, May 2008, July 2011) | 14. Staging of Hodgekin’s disease (July, 2017, Apr. 88)| 615 | 403 3s 15. Histologic types of Hodgekin’s lymphoma 615 | 400 [aa (Apr. 2005, May 2007, Oct, 2001, Sept. 2003) 16. Lumph node in Hodgekin's lymphoma (apr. 94] 614 [400 | 30 V1. Nodular sclerosis type of hodgekin's lymphoma’ 612 | 401 | 38 (May 2007) 18. Mention 4 morphologic characteristics of a myeloblast 617 | 360 | 355 (Jan. 2013) 19. Acute myeloid leukemia (Oct. 96) 617 | 375 338 20. Classify acute "myeloid leukemia (Oct. 92)| 617 | 376 | 338 21, oe Smear and bone marrow picture in acute 596 | 37 | 336. leukemias (apr 87) 338 22. Blood and bone marrow Picture in leukemic leukemia 596 | 347 | 333 (Apr. 87) | 23. Juvenile chronic myeloid leukaemia (Apr 2008)| 622 | 371 {my 24. Peripheral smear in chronic myeloid leukemia 622 | 372 | 34 (Apr. 96, Oct. 04) 25. Spleen in chronic myeloid leukemia Gor 9a] 625 | 371 | 26. Spleenomegaly (Oct 85. 84, Ap: 85] 623 | 385 27, EB virus tomors and infection. ——~—~SCSe myeloproliferative disordei tute myeloblastic leukemia (Ma ing tests for bleeding disorders Give blood ests in a case of chronic myeloid (July. 2017) (Wan. 2015) | 2021 (NTR) (Oct. 85) 349 1 Sere » ER (dan. 2010, Oct. 2001, Apr. 2003) 388 3 POV (duly, 2013, Jan. 2011, Apr. 85) 386 4, Prothrombin time (Oct. 93) [392 5 Clotting time (Oct. 91) | 392 4 Anticoagulant Haematology (Oct. 89) | 380 7. Mention four effects of Radiation. (duly, 2017) | 229 § indications for FNAC and its pitfalls. (Jan. 2016) | 231 | 334 mistry in differentiation of acute leukemias. 9. Cytocher (Jan. 2016) LALLA MISCELLANEOUS FSS Sunerd Very Short Questions + 1 Discuss various processes that participat ota SCR 25 7 Teby Cat” Appearance of heart (Tigered effect) fe in the formation (March, 2010) (March, 2010) a Myeloblast of AML. (March. 2010) 338 § itt ferences between benign and malignant tumours. 338 1 (Apr. 2009) "morphic adenoma. (Apr. 2009) eeShort and Very Short Questions 10. Lipotuscin ‘What are the special stains fo Name four autosomal d SYSTEMIC P pre ‘Name four malignant tumors causing paraneoplastic syndromes. (dan. 2015) on 8] Ay a ‘abnormalities in ekets (duly 2015) 440) Ba Four alcohol induced diseases. Name four myeloproliferative disorders,and Very Short Questions : Robbing | yy, 6. Lipofuscin Wan, 2018] | 7. What are the special stains for fat. (Jan, 2016) alc a $$ 3 8. Name four autosomal dominant diseases, (Jan. 2016)| 14q-] a \* 2 a 9. Name four malignant tumors causing paraneoplastic 329 | ap oN syndromes, (Jan, 2015) % 10, Four alcohol induced diseases. an, 2015)] =| 2a Tay 11. Name four myeloproliferative disorders. (July. 2015)| 623 | 379 ML 12. Four skeletal abnormalities in rickets. (uly, 2015)| 440 | 279 amrk PtioO99 sess YSTEMIC PATHOLOGY aT SSS PE EES eT Ff —— suoy Questions ¢ Aethina | Harshmahan | Wayak tore | area | ave 1, Define atherosclerosis. Discuss the etiology, pathogenesis, | 493 | 412 | 435 morphology, and complications of atherosclerosis, | (Aug. 2019, Apr. 2005, 93) | 2, Classify aneurysms. Discuss in detail their morphological 504 427 | 442 features. Briefly indicate their complications. (Apr. 88) simend Very Short Questions : | 1. Atheroma of aorta (Apr. 2005, Oct. 85)| 502 419 439 2. Complications of atherosclerosis (Aug. 2009, Oct. 86)| 502 41 | 439 3. Morphology and complication of atheroma. 502 | 419 | 439 (Aug. 2021 (KNR) wom: | 3 Mention the site size appearance and common complication 504 | 427 | 872 of berry aneurysm, (dan, 2013) 4 1 Danton and types of Aneurysms. (July. 2013, Oct. 2008)/ 504 | 427 | 442 5 Aneurysms (Feb. 2019, July. 2015, Apr. 2003)| 504 | 427 | 442 6 1 q ony aneurysm (Oct. 2002, 04)| 504 | 427 | 872 5 hie aorts (oa 6] 507 | 422) 404 Disse i ‘ting aneurysms (July, 2017, Jan, 2011, Oct. 93)| 504 | 428 | 444 lebot uy orombosis (Wan, 2011, Oct. 67)| 126 | 430 | 125 "WPhiliti © Aneurysm, (May 2006] 507 | 428 | 444 S.Essay Questions : 1, A59 year old man is admitted with history of chest Pain of half hour duration. Pain was in the precordial area with radiation in the left arm pain was severe in nature and was accompanied by vomiting. ECG showed ST segment elevation with T wave inversion. (Aug. 2019, July. 2017) (a) What is the most likely diagnosis ? (b) What biochemical investigations are useful in such a case ? {c)_ What complications can occur ? () What are the predisposing factors of this disease ? 2. A 68-year old man Presented with left sided chest pain of one hour duration. Pain is radiating to the left arm. ECG demonstrated ST segment elevation with T wave inversion, | (Jan, 2016) (2) Whatis the probable diagnosis? (b) {c) Enumerate the tests you will camry out to diagnose. What is the gross and microscopic picture of the lesion ? (4) What are its complications? (or) Discuss, etiology, pathogenesis and complications of myocardial infarction. (Oct. 90) 542 542pr nussTion BANK (or) male presented with substernal pain radiating srs old coear’ © sweating and dyspnoea, tothe arms, S Whats the provisional diagnosis ? @ (py Discuss the evolution of pathologic changes in this condition? (@) What are the complications ? peseribe the microscopic and macroscopic appearances of myocardial infarct. Briefly mention how it can be diagnosed ane (Oct, 87) 542 542 451 453 458 462, 465 4, Al0 years old female with H/O recurrent fever, upper respiratory tract infection and arthritis, inter ECG abnormalities. Discuss about the causes and come to correct| diagnosis. (Oct. 2002) (or) Describe the macroscopic and microscopic appearances of theumatic mitral valve of the various stages of development| Briefly indicate how an acute rheumatic fever may be diagnosed in laboratory (Oct. 88) 560 560 460 460 474 474 Give an account of etiology, pathogenesis and complications of infective endocarditis (Oct. 96) 563, 467 469 An adult male patient having coarctation of the aorta and Periodontal infection with habit of vigorous brushing of a on to the hospital with fever and anaemia. On sen - there are crops of petechiae over the skin, bet a ‘emorthaes, small tender cutaneous nodules, inate Splenic region and retinal hemorrhages. Urine ‘on shows hematuria. a (March. 2010) Whatis % Probable diagnosis ? D mate 2etlopathogenesis and morphology of lesions le) yp MOUS organs involved. on the complcathns 563 467 469 |ye FALCON’: mn ON'S COMPANION FSR a nt | ae Essay Questions : | Rettig |e I Ming ‘ed with dyspnea and sweating of [sae 451 i 7, 70 year male preent a known hypertensive and diabetic for sudden onset. He is 15 years. On examination he has weak pulse (Mar. 2021 (NTR) (a) What is the diagnosis. (b) Write about pathogen (c) Waite in detail about the morphological changes that occur. (d) Write its complications esis of the above disorder. Short and Very Short Questions saa | 7 a 1, Brown atrophy of heart 544 | 451 | 48 (Aug, 2019, Feb. 2018, Apr. 86) | (Apr 68)| 544 | 452 2, Myocardial infarct 3, Subendocardial infarction 4, Lab findings of myocardial infraction. (apr. 2009,| 544 | 456 | a Sept. 2003,May 2007, Oct. 86) | aeestems ac EE RHEUMATIC FEVER © | {561 | 465 | 4? Short and Very Short Questions : 5, Jones criteria (Apr. 89) 6. Acschoff bodies (Apr. 91, 99, 2005, 2009)| 561 461 fe 7. McCallum patches (apr 84)| 962 | 463 46 oa oe 463 | 4 (Jan. 2012) 562 8. McCallum plagues. 2 Remco eon | | TP 10. Heart in acute rheumatic fever. (Oct. ere 11. Cardiac lesions in rheumatic heart disease. sar ae | (Jan, 2015, Apr. 90) | 12. Pan carditis, a toon) 561 | oe seg | 467 j 469 13. Bacterial endocarditis. (July. 2017, Apr. 2008, 92, 91)| 56: aera 71 ——= “say 168 |“ 14. Vegetations (Oct. 92) | 4guart QwEStTOMs y snare 0 | Nacahnohan |. Naya . Name the Benign and malignant tumors of the penis. 964 | 747 (dan, 2014, Apr. 2010) Essay Question = 1. HSB year old female presented with bleeding per vaginum \ and white discharge. P/v examination revealed unhealthy (Apr. 2005) indurated and ulcerated ce (a) Whatis the probable diagnosis ? (b) What laboratory test will confirm the diagnosis ? (c)_ Whats the histopathology of the diseases ? 2. 35 year old female has 12 weeks amenorrhoea. She is married 1 year ago. On examination uterus size was larger) and corresponding to 20 weeks gestation. She complaints of passing grape like vesicles. Her blood and urine hCG levels are elevated than normal pregnancy. (a) What is the provisional Diagnosis ? (b) Describe gross & microscopic picture of the lesion ? (c)_ Discuss its complications. (July. 2013, Oct. 2008) Short and Very Short Questions : 1. Cervical intraepithelial neoplasia (CVN) (Jan. 2012, Oct. 94, 96) 2 Carcinoma cervix (Squamous cell carcinoma) (Feb 2019, Apr 2008, Oct 97, 90) 995 1025r ; — Pate 0 8 B a a uEsTiON BANK SDS DRE ~ cport Questions? y snort 0 payor mole (July 2011, May 2007) 766 int — s (Apr. 84 janes pr 84) | 1013 | 767 | 746 atonal hyperplasia (Oct. 2004) | 1006 | 768 | 747 no im oma uterts (Jan. 2015, Oct. 88) | 1014 | 772 | 751 Geatieaton of ovarian tumours (July, 2017, Oct 2002) | 1016 | 777 | 753 —_jmomaovary.——SC~=~S~:t:”””S—~C*SMNC 94) 1020 | JOT ER Ffoemous eystadenoma ovary (Oct. 94) | 1020 | 780 | 756 Benign cystic teratoma ovary/Dermoid cyst of the ovary | 1023 | 782 | 759 {aug 2019, July. 2015, Aug. 2011, Apr. 2003, Oct. 2001) Hrawscopic picture of mature Teratoma. (Mar. 2021 (NTR) | 1023 | 782 | 759 Endometriosis (Jan. 2014, Aug. 2009) | 1044 ) 767 | 744 Deine and write about sites involved in endometriosis 1044 | 767 | 744, (Mar, 2021 (NTR) 745 Dysgerminoma (Aug. 2019, Apr. 99) | 1024 | 784 | 761 Morphology of hydatidiform mole (May 2007) | 1033 | 788 | 766 Choriocarcinoma (Apr. 2009, Sep.2003, Oct. 99) | 1025 | 784 | 763 | Name 4 surface epithelial tumors of ovary. (Jan. 2013) | 1017 | 777 | 753 Granulosa cell tumour ovary (Apr. 98) | 1026 | 785 | 763 Cervical carcinoma - in - situ (May. 2006) | 997 | 763 | 738 Brenner tumour (apr. 2010) | 1022 | 782 | 758 Krukenderg tumor. (Aug. 2021 (KNR) | 1028 | 786 | 765 25. BREAST "Questions: 1 an 0 year old female presented with a painless slowly ni freely mobile solitary lump in the lower part of her "east. On examination the nipple is normal. The lump Wot xed to the on epaanye M2 vena skin, No axillary ymphnodes 1042 797 ee ee1y Questions : Robi (a) What is the provisional diagnosis ? ins (b) Discuss various investigations to confirm your final diagnosis. (c) Describe the gross and microscopic picture of the lesion, (4pr. 2009) 2. 40 year old female presented with lump in the breast, The Tigac 1046 lump Is hard and adhered the underlying structures and m3 aullary Iymphnodes are enlarged. (Feb, 2019, Aug, 2010) {a) What is the provisional diagnosis hort and Very Short Questions : 1, Fibrocystic disease of the breast (Apr. 2003)| 1042 7% 2. Fibroadenoma (Oct. 2008, Apr, 84, 2009)| 1062 786 3. Cystosarcoma phyllodes (Apr. 88, 2008)| 1062 787 4. Prognostic factors of breast carcinoma (May 2007)| 1058 785 5. Paget's disease of nipple (Jan. 2012, Oct, 2001)| 1058 783 6. Fibroadenoma, (Apr. 84, Oct. 2008)| 1058 786 7. Phyllodes tumour (Aug, 2019, Apr, 2008)| 1062 78) 8. Gross and microscopie appearance of carcinoma breast | 1063 m. (Jan, 2016, Apr. 92, May 2007) 9. Gynecomastia (Oct. 86), 1044 2 10. Medullary carcinoma af brea (March, 2021 (NTR)| 1057 780 11. Clesstiation of brenat carcinoma (Aug, 2021 (KNR)| 1053 mh Short and Very Short Questions t 1, Calcitonsin 1091 792,804) 2, Hashimoto thyroiditis Ta) 70 May 2007, Or goon} TORT | “apauses Questions : | sis et. 2002) | 1081 | 847 | 797 4, evesotte (Apr. 97, 98) | 1082 | 847 | 797 Goitte 5 (0. T1089 | aap 5, Getrogens 86) | 1082 | 848 | 797 pf | ‘Adenoma thyroid (Oct, 2004, 90) | 1085 | 851 | 800 eo ee jalary carcinoma of thyroi 1091 | 855 | 806 Med gM (Jan, 2012, Apr. 93, Oct. 93) | 4 yperparathyroidism (Jan. 2011, Oct. 97) | 1093 | 858 | 808 (Feb. 2019, Oct. 98) | 1115 | 838 811 (Oct. 2008, 84, May. 2006) | 1127 | 840 | 816 1 (4pr. 2010, 90)| 477 | 841 | 818 sn. Coshig syndrome 11, Pheochromocytoma 12, Neuroblastoma 18. Tiple response. (May 2007, - | 72 | 14, Microscopic patterns of follicular adenoma thyroid. 1093 | 851 | 800 (Jan. 2016) | (Feb. 2020 (KNR) | 1086 | 1089 | 804 16. Pathogenesis and complication of diabetes mellitu. 1107, | 862 | 822, (Mar, 2021 (NTR) | 1108 | 823, 15, Pepilary carcinoma and thyroid. ‘intend Very Short Questions : | 1 Malignant melanoma (Feb. 2020 (KNR), | 1139 dan, 2015, Aug, 2010,0ct. 2009, 85, 83, Apr. 2008, 87) 1137 | 822 | 867 a Premalignant conditions of skin (Jan, 2011, May 2007) [1146 | 822 | 867 1147 | 824 3 Squamous cell carcinoma 4 8, “slcell carcinoma (Rodent ulcer) (May 2006, Oct. 20044pr. 98) ———e 1137 | 822 | 867 | 5 Pro ‘mallnant conditions of skin ae h Tiss] 518 | - " Planus. (Mar 2021 (NTR) | 1158 | S18 | - MwEssay Questions : — a Mai | 1. Desc the eng of facture. Enumerate the causes fr | pe non-union of fracture (Apr 99) Short and Very Short Questions : | 1. Paget's disease of bone (Ostets deformans) apr ay 2. Ostet fibrosa cystica (Oc. 7) 3. Healing of fracture (Feb, 2019, Apr 84)) 1 ) 4. Osteomyelitis - Tuberculosis (Apr. 05, 2008, Oct. 98, of Classification of tumors olbone 5. Classification of tumors of bone (Apr. 89) 6. Osteosarcoma (May 06, Sep. 03, Apr. 90, 96) ) | 7. Gross appearance of osteogenic sarcoma. 1188 | 885 |i) (Feb, 2018, July. 2015) eS 8. Chondroma (Oct. 95)| 1190 | 892 | aH 9. Ewing sarcoma (Wan, 2014,| 1192 | 891 | 848 Apr. 98, May 2007, Oct. 93, 2002) 10. Giant cell tumour (Osteoclastoma) (July. 2017, 2015| 1193 | 889 | 845 (duly 2013, 2011, Apr. 97, 99, 03, Oct. 90, 01, 2008) tbe Gout (May 2006, Oct. 86)] 1204 | 897 | 894 12. Pyogentic osteomyelitis (Apr. 2009, 2011) 873 | 87 13. Mention four histological sub-iypes of Osteosarcoma. (Mar. 2021 (NTR) TET SA Short and Very Short Questions : 1185 | 1. Cerebral infraction (Oct. 87)) 1255 2. Berry aneurysm (Oct. 2002) 1260 | 3. CSF findings in pyogenic meningitis (Aug. 2021 (KNR), (Feb, 2020 (KNR)Oct. 2001, 99, 93, Apr. 99) 1262 | 1188 | 884 | 842 927 | 810 929 al 921 |ape pf | * (Sept. 2003, Apr. 97) | 1293 | 935 | 878 | weston {oo} | 3. Cell membrane 13 mn | 4. Reverse transcriptase (Oct. 94) = Si = | 5. Warthin tumours | - | 56 [se | | 6. Three causes of primary hyperparathyroidism and one | 1093 | 858 | 808, cause of secondary hyperparathyroidism. | | sia (Jan, zo