CS/B Se(NY/BT/MicrofGEN/Odd/SEM-1/CBT-102(N)/ CMC-102(Ny/ CGN-102(N) 2018-19 MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY, WEST BENGAL Paper Code CBT-102/CGN-102/CMC-102 CELL BIOLOGY Time Allotted: 3 Hours Full Marks: 70 The figures in the margin indicate full marks. Candidates are required to give their answers in their own words as far as practicable. Group -A (Multiple Choice Type Questions) 1. Choose the comect alternative for any ten of the followings 1x10=10 (i) Which ofthe following cellular structures is not seen in both prokaryotes and eukaryotes? (a) Mitochondria (b) Ribosomes (@) Acell wall (a) DNA Gi) Which one of the folowing plays a role as storage granule in bacteria’ (a) mesosome (b) ribosome (©) PHB (a) capsule ii) Prokaryotic cells does not contain (a) nucleoid (b) cell membrane (6) 80S ribosome (@) 70S ribosome iv) Lysozyme is ineffective against Mycoplasma because (a) it Lacks cell wall. (b) it lacks true nucleus, (©) itcontain sterols. (d) None of these () Which ofthe following statement is tre for the mordant used in Gram staining? (a) lodine is used as mordant and it form a complex with safranine. (6) Tone is used as mordant and it form insoluble complex with crystal violet, {) Ethanol is used as mordant and it dehydrates the ell (@) Crystal violet is used as @ mordant and it form an insoluble complex with iodine.(CPB Se(NV/BT/Micro/GEN/Odd/SEM -1/CBT-102(NY/ CMC-102(NV/ CGN-102(NV/2018-19 (vi) Thickness of biological membrane is (a) 25m (b) Sto 8nm © 254° (a) 5-84" (vii) GLUT is an example of (@) Active Transporter (b) ABC Transporter (©) Facilitated Diffuser (d) Passive Transporter (ill) ‘The largest subunit of prokaryotic ribosome is (@ 308 (b) 508 “ (©) 408 () 60S Y (ix) Which one of the following is anti-apoptotic protein’? (@) Bax (b) PUMA, (©) NOXA (@) Bel-2 (9) Na’ Glucose transport is an example of (a) Symport (b) Uniport (©) Antiport (@) ATP driven transport (ai) LDL is transported by (a) Phagocytosis (b) Catherin mediated (©) Caveole mediated (4) All of these (sii) The bacteria responsible for origin of mitochondria is (a) Bacillus subsitis (b) Pseudomonas aeruginosa (©) Treponema pallidum (d) Rickettsia prowazekii —~ (ili) The cartier for N-linked Glycosylation (@) Dolicol (b) Tunicamyein (©) Calnexin @ Flagetiin (xiv) Which ofthe Following lipid ageregates isthe precursors of the first living cell? (a) Micelle (b) Bilayer (©) Liposome (d) None of these Gv) Fluid mosaic model forthe biological membranes was proposed in (a) 1970 (b) 1972 (©) 1978 (a) 1980 2CS/B.Se(NV/BT/Micro/GEN/Odd/SEM- I/CBT-102(N)/ CMC-102(NV CGN-102(NV/2018-19 (xvi) You are told that the cells on a microscope slide are plant, animal or bacterial. You look at them through a microscope and see cell walls and membrane-bound organelles. You conclude that the cells (a) are plant cells, () could be either plant or bacterial. (©) are animal cells. (4) could be plant, animal or bacterial (avii) Teichoic acid are found in (a) Gram positive bacteria (b) Gram negative bacteria (©) Acid fast bacteria (@) None of these Group -B (Short Answer Type Questions) Answer any three of the following. Sx3=15 What are cell adhesion molecules? Write a short note on cadherin. 14425 Name and describe the structure and chemical composition of the specialized resistant forms found in some Gram positive bacteria. ‘Which type of cell came first in evolution? What is The Cell Theory? What structure can be found in all living cells? 2424155 ‘What structures make up the nuclear membrane? What is nuclear lamina? What is its function? 3+1+1=5 How mesosomes are important structures in bacteria? Where is S layer found? 44155 How can you compare eukaryotic and prokaryotic ribosome on the basis of FRNA composition? Which FRNA of prokaryote can be used in taxonomic analyses? What is the function of SER in human liver? De142=5 Explain Na’ ~ K* pump as a demonstration of endergonic ion movement coupled to an exergonic process. ‘What are voltages gated channels and ligand-gated channels? 34265 How p® brings about cell eycle arrest. Elaborate the role of Enzyme-linked receptors in signal transduction, ‘What is the conclusion of Patch Clamp Experiment?| CS/B.Se(N/BT/MicrofGEN/Odd/SEM-1/CBT-102{NJ/ CMC-102(NY CGN-1021NY2018-19 2. 13. 4, 15. 16. 1. 18. 19, Group-C (Long Answer Type Questions) Answer any three of the following. 15x3=45 lusidate Fick's Law of Diffusion? How ABC trisporer and active transport mechanism helps in fransporting molecules into the cell? What do you mean by TRISKELION? Elaborate the role of Caveolin in Pinocytosis? 340424415 Differentiate Apoptosis from Necrosis. What is the function of FADD in apoptosis? How is Bel-2 ‘sponsible for inhibiting and inducing apoptosis? Differentiate intrinsic and extrinsic pathway of apoptosis, 2434545215, (@) What is the eel! cycle? Does cell division happen during the entire cell cycle? In general, which Phase of the cell cycle takes more time? What events mark the beginning and the end of the first tage of interphase and what happens within the cell during this stage? What events mark the beginning and the end ofthe second stage of interphase and what happens inthe cell duting this stage? What events mark the beginning and the end of the third stage of interphase and what happens in the cell during this stage? (©) What are check points in cell eycle? Briefly explain the role of them in cell cycle? (2414 1424242)4243=15 Discuss the stricture of the biological membrane with diagram. What are lipid aggregates? Discuss briefly the criteria of major lipid aggregates, OF 145=15 ‘What is cell fractionation? What are the major steps involved in cell fractionation? Discuss the uses of centrifugation techniques in cell fractionation, What are the advantages and disadvantages of cell fractionation? 1424943615 ‘What are cell junctions? What major kind of cel junctions are found in vertebrates? Discuss the structure of any one of them. What are Plasmodesmata? Discuss its structural organization with a diagram and ‘mention its functions, 1424de1e4e3=15, ‘What is the role of nucleus in protein synthesis? What is nucleolus? Give theit function. Desevibe structure of nuclear pore. Give mechanism of transport across it 341424445215 Nia! ate the mechanism for biogenesis of mitochondria and chloroplast? What i the role played by N-alycosylation? What is Signal sequence and how protein is targeted to endoplasmic reticulum? Differentiate the Function of Endoplasmic reticulum and Golgi in terms of Protein sorting, 643+3+3¢15