GGT
bile obstruction
inflammatory conditions, raised when RBC breakdown
protein production in total bilirubin produces more unconjugated
urine bilirubin than liver can handle
low in loss of liver tissue liver disease
Albumin
made in liver bile duct blockage
e.g. gall stones
bile duct pressure increase
ALP ALT rises more than AST in
Liver function tests liver damage and
hepatitis (inflammation)
bone disease
more specific for liver
indicates inflammation and cell death
low in excessive ALT:AST - high ALT chronic liver
tissue loss or long disease, high AST- cirrhosis
standing disease Albumin AST
not specific
for coag tendencies - increased in liver disease normal in liver disease
Total protein total protein - albumin = globulin
long PT - deficiency of clotting
factors made by liver high values in hepatitis (also autoimmune hep)
Prothrombin time
vit K deficiency