QUESTION BANK

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BIOMOLECULES
CLASS-12 (CBSE)

S. No Question Year
1. Define
a. Fibrous protein 2020
b. Invert sugar 2020, 2019, 2010(D)
c. Native protein 2020, 2019
d. Polysaccharides 2020, 2019
e. Glycosidic linkage 2020, 2009(D)
f. Oligosaccharides 2020, 2019
g. Denaturation of protein 2020, 2019, 2008(D)
h. Vitamins 2019
i. Nucleotide 2019
j. Anomers 2019
k. Essential amino acids 2019
l. Tertiary structure of protein 2019
m. Disaccharides 2019
n. Denatured protein 2019
o. Peptide Linkage 2019,2012,2009(D), 2008(D)
p. Primary structure 2014
q. Biocatalyst 2014
r. Polypeptides 2010(D)
2. Differentiate between the following

a. Amylose and Amylopectin 2020, 2019

b. Globular protein and Fibrous protein 2020, 2019, 2015
c. Nucleotide and Nucleoside 2020, 2019, 2016(D)
d. Peptide linkage and Glycosidic linkage 2020
e. Essential amino acids and Non-essential amino acids 2019
f. Starch and glucose 2019
g. DNA and RNA 2019
h. Native and denatured protein 2019
3. Give the plausible explanation for the following : 2020
(a) Glucose doesn’t give 2,4-DNP test.
(b) The two strands in DNA are not identical but are complementary.
(c) Starch and cellulose both contain glucose unit as monomer, yet they are structurally different
4. Organic compounds containing amine as functional group are present in a vivid variety of 2020
compounds, namely amino acids, hormones, neurotransmitters, DNA, alkaloids, dyes, etc. Drugs
including nicotine, morphine, codeine and heroin, etc. which have physiological effects on
humans also contain amino group in one form or another. Amines are basic because of the
presence of lone pair of electrons on nitrogen. Addition of nitrogen into an organic framework
leads to the formation of two families of molecules, namely amines and amides. As chemistry
students, we must appreciate the versatility of nitrogen.
1. What are amino acids ?
2. Why are amino acids amphoteric ?
3. Give one point of difference between acidic and basic amino acid.
4. What are essential amino acids ?
5. Name the linkage formed when carboxyl end of one amino acid condenses with amino end of
other amino acid.
5. Name the disaccharide which on hydrolysis gives two molecules of glucose. 2020
6. Name the disaccharide which on hydrolysis gives glucose and galactose. 2020
7. Name the vitamin whose deficiency causes convulsions. 2020
8. (a) How can you explain the absence of an aldehyde group in the pentaacetate of D-glucose ? 2020
(b) Name the bases present in RNA. Which one of these is not present in DNA ?
 QUESTION BANK

9.
Toaster
BIOMOLECULES
CLASS-12 (CBSE)
Write the reactions showing the presence of following in the open structure of glucose : 2020
(i) a carbonyl group
(ii) Straight chain with six carbon atoms
10. Write the name of linkage joining two monosaccharides. 2020
11. Write the reactions showing the presence of following in the open structure of glucose : 2020
(i) an aldehyde group
(ii) a primary alcohol
12. What type of protein is present in keratin ? 2020
13. Write the reactions showing the presence of following in the open structure of glucose : 2020
(i) five –OH groups (ii) a carbonyl group
14. (i) What are the hydrolysis products of DNA ? 2020
(ii) What happens when D-glucose is treated with Bromine water ?
(iii) What is the effect of denaturation on the structure of proteins ?
15. What is the basic structural difference between glucose and fructose ? 2019
OR
Write the products obtained after hydrolysis of lactose.
16. Write chemical reactions to show that open structure of D-glucose contains the 2019
following :
(i) Straight chain (ii) Five alcohol groups (iii) Aldehyde as carbonyl group
17. Write the reactions involved when D-glucose is treated with the following reagents : 2019
(i) Br2 water (ii) H2N-OH (iii) (CH3CO)2O
18. What is the basic structural difference between starch and cellulose ? 2019
OR
Write the products obtained after hydrolysis of DNA.
19. (a) What are the products of hydrolysis of maltose ? 2019
(b) What type of bonding provides stability to -helix structure of protein ?
(c) Name the vitamin whose deficiency causes pernicious anaemia.
20. (a) Write the product when D-glucose reacts with Br2 (aq). 2019
(b) What type of bonding provides stability to -helix structure of protein ?
(c) Name the vitamin whose deficiency causes pernicious anaemia.
21. (a) Give any one property of glucose that cannot be explained by the open chain structure. 2019
(b) Compare amylase with amylopectin in terms of constituting structure.
(c) Why do amino acids show amphoteric behaviour ?
22. What happens when D-Glucose is treated with the following reagents : 2019
(a) Br2 water (b) HCN (c) (CH3CO)2O
23. (a)Which one of the following is a disaccharide : 2019
Glucose, Lactose, Amylose, Fructose
(b) Write the name of the vitamin responsible for the coagulation of blood.
24. What happens when D-glucose is treated with the following ? Give equations to support your 2019
answer.
(a) HI (b) HNO3
25. (a) Write the product when D-glucose reacts with conc. HNO3. 2018
(b) Amino acids show amphoteric behaviour. Why?
(c) Write one difference between α-helix and β-pleated structures of proteins.
26. (a) Which polysaccharide component of carbohydrates is commonly present in bread ? 2017(OD)
(b) Write the two types of secondary structures of proteins. 2017(D)
(c) Give two examples of water soluble vitamins. 2217(F)
27. (i) Write the structural difference between starch and cellulose. 2016 (OD)
(ii) What type of linkage is present in Nucleic acids.
(iii) Give one example each for fibrous protein and globular protein.
28. (i) Write the name of two monosaccharides obtained on hydrolysis of lactose sugar. 2016(D)
(ii) Why Vitamin C cannot be stored in our body?
 QUESTION BANK

29.
Forego
BIOMOLECULES
CLASS-12 (CBSE)
(i) Which one of the following is a Polysaccharide: starch, maltose, fructose, glucose 2015(OD)
(ii) Write one difference between 𝜶-helix and 𝜷-pleated sheet structures of protein.
(iii) Write the name of the disease caused by the deficiency of vitamin 𝑩𝟏𝟐.
30. (i) Which one of the following is a disaccharide: Starch, Maltose, Fructose, Glucose? 2015(D)
(ii) Write the name of vitamin whose deficiency causes bone deformities in children.
31. What are the products of hydrolysis of sucrose? 2014(OD)
2013(OD)
32. (i) Deficiency of which vitamin causes night-blindness? 2014(D)
(ii) Name the base that if found in nucleonic of RNA only.
(iii) Glucose on reaction with HI given n-hexane. What goes it suggest about the structure of
glucose?
33. (i) Name the vitamin whose deficiency causes ‘pernicious anemia’. 2013(OD)
(ii) Give an example of a water soluble vitamin.
34. What are three types of RNA molecules which perform different functions? 2013(D)
35. Give two examples of water-soluble vitamins. 2013(D)
36. Write the structure of the product obtained when glucose is oxidized with nitric acid. 2012(OD)
37. What is essentially the difference between 𝛂-glucose and 𝛃-glucose? What is meant by pyranose 2012(OD)
structure of glucose? 2011(D)
38. Write any two reactions of glucose which cannot be explained be the open chain structure of 2012(D)
glucose molecule.
39. Write the main structure difference between DNA and RNA. Of the four bases, name those which 2011(OD)
are common to both DNA and RNA.
40. Describe what you understand by primary structure and secondary structure of proteins. 2011(D)
41. What is meant by ‘reducing sugars’? 2010(OD)
42. Amino acids may be acidic, alkaline or neutral, how does this happen? What are essential and 2010(OD)
nonessential amino acids? Name one of each type.
43. Name the four has bases present in DNA. Which one of these is not present in RNA? 2009(OD)
44. Name two fat soluble vitamins, their sources and the diseases caused due to their deficiency in 2009(OD)
diet.
45. Name two water soluble vitamins, their sources and the diseases caused due to their deficiency in 2009(D)
diet.
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