drug which have the same site of action of penicillin -1

a-tetracycline
b-cephalexin
c-chloramephinechol
d-amphotericin
provac drug -2
a- anticoagulant
b-antibiotic
c-antiplatlets
..………-d
salbutamol -3
a-bronchodilator
phenyephrin-4
a- alpha &beta acion
b- alpha action
c-beta action
d-nicotinic
e-mucascarinic
phentolamine (ask for receptors) as question4-5
category C FDA pregnancy drugs-6
declofenac used in gout-7
a-anti-inflammatory and analgesic only
b-uricosuric agent
c-prevent excessive damage of joints
allopuruinol-8
a- uricosuric agent
b-increase absorption of uric a in tubules
....side effect of nitrate-9
..…claritin anti-10
patient has apenicillin allergy suitable antibiotic -11
a-penicillin
b-cephalexin
c-erythromycin
d-cloxacillin
e-augmentin(clavulinic )
.…… tyramine+ACEI-12
membrane filters with 0.22 micropores , which of following not -13
?removed by that
heparin mechanism to prevent clot -14
..……
heparin test -15
..……
ophthalmic common traditional in market -16
a-solution-oint-suspension
b-solution- susp-oint
c-susp-oint – solution
d-all are common the same
 needed to be sterile -17
a-parentral
b-syrup
.c-ophalamic prep
d-a&c
hypertonic solution make-18
shrinkage of blood cell-1
hemolysis-2
hyperglycemia-3
hypoglycemia-4
a&c-5
adenosine cause -19
Flushing –dyspnea
obse diabetic take firstly metformin -20
o.d means -21
a.c means -22
t.d means-23
about aminglcosides what is false -24
vitamin c for adult female-25
a-25mg
b-40mg
c-90mg
which of the following not antifungal -26
guanthedin SE-27
a-prevent ejaculation
b-sever hypotension
-c ‫مش فاكر‬
……………bioavilability -28
process of drug metabolism in intestine -29
a-hydrolsis
b-oxid
c-glucouroniatin
……-d
digoxin-30
Increase contractility of myocardium
clonidine-31
-32
acid –base law -33
a-henry's
b-mivhelis menten
c- frank
‫ كمان شوية اسماء مش فاكرهم‬-d
not from blood cells -34
a- reticleucyte
omperazole-35
Decrease acidity
 ? Which of the following is not betamethasone side effect -36
a-cataract
b-hypoglycemia
c-skeletal muscle weakness
d-sodium retention
-37
The mechanism of action of atropine is15
a-muscarinic antagonist b-muscarinic agonist
c-nicotinic antagonist d-nicotinic agonist
e-non of the above
We can prepare 100 ml of 12% MgCl2 by taking -38
a-12g solute in 100ml solvent
b-12mg solute in 1000ml solvent
c-12g solute in 1ooml solvent
d-12mg solute in 100ml solvent
..……what is tertiary amine of TCA -38
vit A not used with-39
a-scurvy
b-night blindness
c-pregnancy
..…-d
: process require CYP450_-40
a)oxidation
b)hydrolsis
)c

: heparin monitoring-41
a) INR
b) PT
c) APTT

how much amount of water added to 250 ml of solution as 1/500 of

benzonium clorid to be 1/2000
a_0.125 L
b_0.250 L
c_0.4 L
d_2 L
e_ 4 L
‫لحد دلوقتي مشوفتش حل لها‬
‫ مرات‬4 ‫ يعني تضاعف‬1/2000 ‫ وقل بقي‬1/500 ‫بس احتمال تبقي كده التركيز االصلي‬
‫ لتر مثال‬1 ‫يبقي المفروض‬
‫لتر وشكلها طلعت صح‬2 ‫بس المهم انا اخترت‬
molality ‫الني محلتش مسألة‬

The Molal concentration of 0.559 M is (Mwt=331.23 &

:density=1.157g/ml) is
 ‫كمان كان فيه مسألة التحويل من باوند الي كيلو وحساب الجرعة للجسم كله فاعرفو كيفية التحويل‬
‫ون كيلو الي باوند والعكس‬

The major action of sodium chromoglycate -1

-:is
a-mast cell stabilization b-bronchodilator
c-prostaglandins modifier d-leukotrienes modifier e-non of the
above
: The action of histamine is-2
a-capillary constriction b-elevation of blood pressure
c-stimulation of gastric secretion
d-skeletal muscle paralysis e-slowing the heart rate

One of the following antibiotics is resistant to-3

: penicillinase
a-penicillin V b-penicillin G
c-floxapen d-ampicillin
e-amoxicillin
: Inderal is -4
a-similar in action to ergotamine
b-similar in action to tubocurarine
c-used as an antihistamine
d-pure b -adrenergic receptor blocker
: Rifampicin is indicated for treatment of -5
a-impaired fat absorption b-pulmonary emboli
c-tuberculosis d-neoplastic disorders
e-psoriasis
Which of the following is non selective b1 -6
? blocker
a-labitolol b-terazosine
c-cloridine d-captopril
e-verapamil
: The Latin abbreviation for " After Meals " is -7
.a- a.c. b- a.a. c- p.c. d- i.c. e- c.c
The latin abbreviation for " Four Times Daily " -8
 : is
.a- a.c. b- a.a. c- p.c. d- q.i.d. e- c.c
: The latin abbreviation for " Every Night " is -9
.a- a.c. b- o.n. c- p.c. d- i.c. e- c.c

: Erythroped A -10
a-is effective against G +ve Cocci
b-is a macrolide antibiotic
c-can increase g.i.t. motility
d-could be used in pregnant women if need
e-all of the above

For the treatment of anaphylactic shock -11

: use
a-salbutamol b-diphenhydramine
c-acetazolamide d-epinephrine
e-aminophylline
: Allopurinol is used as -12
a-analgesic agent b-uricosuric agent
c-antiinflamatory agent d-antipyretic agent
e-agent which increases renal tubular reabsorption
Allopurinol inhibits xanthine oxidase, reducing the conversion of
hypoxanthine and xanthine to uric acid and resulting in direct
inhibition
of purine biosynthesis due to elevated oxypurine concentration
(negative
feedback). Oxypurinol also inhibits xanthine oxidase. So anyway
you have
dramatically decreased uric acid concentrations, decreased renal
tubular
transport of uric acid, and then the side effect of increased tubular
.reabsorption of calcium
Which of the following is NOT -13
? betamethasone side effect
A-cataract b-hypoglycemia
c-skeletal muscle weakness d-sodium retention
e-lowered resistance to infections
: A disease which is due to viral infection -14
a-poliomyelitis b-rabies
c-chicken pox d-herpes
e-all of the above
 : The mechanism of action of atropine is -15
a-muscarinic antagonist b-muscarinic agonist
c-nicotinic antagonist d-nicotinic agonist
e-non of the above

Myocardial muscle tissue property to -16

: generate electrical is
a-inotropy b-chronotropy
c-automaticity d-contractility
"e-non of the above " Dromotropic effect

: The heart`s dominant pacemaker is -17

a- AV node b- SA node
c-pukinje fiber d-internodal pathways
e-non of the above
: Adenosine is used for -18
a-ventricular arrythmias b-atrial bradycardia
c-supraventricular tachycardia
d-supraventricular bradycardia
e-non of the above

Adenosine P produces which of the -19

: following
a-facial flushing b-dyspnea c-marked tachycardia d- a and b e- a , b
and c

Which of the following is responcible for -20

buffering
a-magnesium b-chloride c-bicarbonates d-potassium e-troponin

: Respiratory acidosis is due to -21

a- O2 removal b- O2 retention
c- CO2 removal d- CO2 retention
e-non of the above

Which of the following is NOT colloid -22

? solution
a-albumin 5% b-ringer`s solution
c-dextran d-beta starch
e-albumin 20%
 : The term shock signifies -23
a-hyperperfusion b-hypoperfusion c-tachycardia
d-bradycardia e-non of the above

In treatment of shock , which of the -24

?following should be considered
a-airway control b-IV of crystalloid solution
c-dopamine to support blood pressure
d-monitor heart rhythm e-all of the above

Which of the following is released by -25

bacterial infection?(…. by bacterial cell wall
during there growth)
a-endotoxin b-exotoxin c-antibiotics
d-cytotoxin e-non of the above

:the amount of water in adult male is about -26

a-25% b-60% c-80% d-10% e-17%

Which of the following are causes of -27

?oedema
a- Increase hydrostatic pressure
b- Decrease oncotic pressure
c-capillary permeability
d- a and b e- a , b and
Patients prescribed non reversible -28
monoamine oxidase inhibitor should be advised
not to consume food containing tyramine
:because this combination causes
a-postural hypotension b-hallucinations
c-anaphylactic shock d-muscle weakness and tremor e-acute
adrenergic crisis including sever hypertention

Concerning COX 2 inhibitors , which is NOT -29

?true
a-they have lower risk gastric adverse reactions
b-good evidence about their effectiveness
c-cardiac toxicity is a recent concern of this class
d-they usually administrated twice daily
e-combination with non selective agents give more effective action
 In the treatment of osteoporosis which of -30
?the following is NOT true
a-alendronate should be taken 60 min. before breakfast
b-Ca and vit. D are essential
c-hormone replacement therapy should be considered
d-outcome should be assessed with periodic bone density
e-raloxifeno is selective oestrogen modulator

Which of the following is the first choice in -31

?acute gout
a-allopurinol b-indomethacin c-colchicine d-probencid e-
sulfinylpyrazone

Which of the following is NOT a risk factor -32

?for osteoparalysis
a-minimal exercise b-low calcium intake
c-male gender d-family history
e-minimal exposure to sunlight

: Early symptoms of aspirin poisoning are -33

a-lethergy & fatigue b-skin rash & headache
c-throbbing headache & dizziness
d-fluid retention hypotension
e-ringing in the ears & blurred vision

Which of the following is NOT true about -34

infiximuab
a-IL-1 blocker
b-used for treatment of severe rheumatoid arthritis c-may increase
risk of infections
d-administered as IV infusion
e-postadministration reactions include fever & chills

A disease modifying drugs in rheumatoid -35

:arthritis
a-gold preparations b-hydroxychloroquine
c-methotrexate d- a and b
e- a , b and c
A patient who is admitted through the E.R. -36
: with an initial diagnosis
 a-slow ventricular response using verapamil
b-start lidocaine infusion
c- considered anticoagulation with warfarine
d- a and b e- b and c
Which of the following is true about surgical -37
? prophylaxis
a-it is given to treat surgery associated infections
b-it is given to reduce the possibility of surgical site infection
c-should always be given regardless type of surgery
d-should be continued for 7 days after surgery
e-all are true
When diagnosis of diabetes to be -38
: considered
a-WBC count with differential
b-oral glucose tolerance test c- HBA1c
d- a and b e- b and c
The usual daily dose of phenytoin in the -39
:range of
a- 1-5 mg b- 15-60 mg
c- 300-600 d -should be continued for 7 days after surgery
e-all are true
Goals of diabetes mellitus management -40
: include
a-reduce onset of complications
b-control symptoms of diabetes
c-near normal glycemic control and HBA1c
d- a and b e- a , b and c

When dosing insulin which of the following -41

?is true
a-initial dose 0.6 u / kg / day split 2/3 a.m and 1/3 p.m
b-regular NPH ratio is 1 : 1 or 1 : 2
c-dose may need to be increased during acute illness
d- b and c e- a , b and c
What first line agent may be considered for -42
? an obese type 2
a-glyburinid b-insulin c-metformin
d-nateglinid e-repaglinid

41-30gm of 1% hydrocortisone mixed with 40

 gm 2.5% hydrocortisonen what is the
concentration of the resulting
?solution
a) 3% b) 1.85%
c)10%d) none of the above
30gm--------------1% ------------=0.3gm
40gm--------------2.5% --------------=1gm
So, 70gm-------------X%--------------=1.3
So, the con. Result =1.3/70=1.857%
These are non aqueous pharmaceutical -42
:solutions
.a-otic soln. , mouth washes and nasal soln
b-essences , collodions an elixirs
.c-gargles , douches and irrigation soln
d-syrups , mucillages and collodions
e-enemas , liniments and spirits
A solution is made by dissolving 17.52 g of -43
NaCl exactly 2000 ml. What is the molarity of
?this solution
a- 3.33 b- 0.15
c- 1.60 d-3.00 x 10 -4 e-1.6x10 -4
Morality=mole/volume (L)
Mole=molecular weight of subs. In 1 grams
So, molecular weight of NACL=23+34=57
So, Mole=17.52/57=0.307
So, Morality=0.307/2=0.153
Which of the following drugs exhibits dose -44
? dependant pharmaceutical therapeutic doses
a-Na valproate b-phenytoin c-lithium
d-quinidine e-carbamazepine
Propranolol is often prescribed with -45
hydralazine to
a-reduce the reflex tachycardia b-prevent the accumulation of
hydralazine
c-prevent systemic lupus ( SLE ) due to hydralazine d-prevent
oedemae-increase absorption of hydralazine
: The ability of a liquid to dissolve is -46
a-hydrophilicity b-miscibility
c-immiscibility d-solubility equilibrium
? Which of the following is NOT correct -47
 a-glitazones are ineffective as mono therapy
b-GIT disturbance are common side effects of glycosidase
inhibitors-a
c-start with small dose of oral agent and triturate up to 1-2 weeks
d-life style modification should not be enforced if an oral agent to
be started
e-lisepro is rapid acting insulin to be dosed immediately before
meals

In CHF management the following is not -48

:correct
a-ACEIs such as lisinopril improves left ventricular function and
reduces mortality
blocker such as carvidailol may have beneficialb b- effect in -
selected patient
c-spironolactone should be avoided because of the great risk of
hypokalemia
d-non drug therapy includes appropriate fluid and dietary sodium-
restriction
e-symptomatic improvement is one of the major assessment
criteria for proper therapy

Which of the following is NOT a primary -49

literature
a-gournal of pharmacy practice
b-applied therapeutic & clinical use of drug
c-new England Journal of medicine
d-Loncet
e- JAMA

References to check compatibility of drugs -50

:in parentral administration
a- MERCK Index
b-handbook on injectable drugs
c-micromedix d- a and b e- b and c

When a CNS depressant is prescribed , -51

which of the following is NOT taken at the same
?time
a-analgesic b-verapamil
c-aspirin d-diphenhydramine e-orange juice
 A 4 mg dose of lorazepam administered to a -52
: adult will act as
a-analgesic b-hypnotic c-diuretic
d-antihistaminic e-antiulcerant

The drug of choice to control pain during -53

: acute myocardial infarction is
a-naloxone b-bethidine c-morphine
d-celecoxib e-naproxen
What is a major contraindication to the use -54
of an OTC sympathomimetic drug
a-gastric ulcer b-uncontrolled hypotension
c-severe asthma d-rheumatoid arthritis
e-hypertension

Category C in FDA for drug used in-55

: pregnancy
a- controlled studies fail to demonstrate a risk to the fetus in the
trimester and there is no evidence of risk in later trimester
b- fetal risk NOT demonstrated in animal studies but there are no
controlled studies in pregnant women or animal reproduction
studies have shown an adverse effect that was NOT confirmed in
controlled studies in women during trimester
c-either animal study have revealed adverse effect on the fetus and
there are no controlled human studies or studies in animal and
women are not available
d- There is positive evidence of human fetal risk but the benefits of
use in pregnant woman may be acceptable despite the risk
What advice would you give to a patient -56
?prescribed rifampicin
a-take this medication with food or milk
b-avoid multivitamine preparations during treatment
c-avoid taking paracetamol during treatment
d-possible discolouration of skin is of no importance
e-this medication may cause discolouration of urine
Correct method of parentral administration -57
: of potassium is
a-fast I.V. injection
b-slow I.V. injection c-I.M. injection
d-IP(intraperitoneal) injection
Which route of administration would provide -58
 the most rapid onset of action response to
? morphine
.a-oral b-S.C. c-I.V
d-I.M. e-rectal
The long term administration of thiazide -59
: diuretics requires
++a- K+ b- Na+ c- Ca
d- CO3 e- acetate
:Fifty micrograms equals -60
?a-50000 ( nanogrames )? b- 0.05 ( milligrams )
c- 0.0005 g
d- a and b
e- a and c
When concidering drug therapy for -61
?hypertention , which is true
a-combination of drugs always preferred
b-hydralazine is first line therapy in young hypertension
c-furosemide should be administrated before meal to improve
absorption
d-beta-blokers should be avoided in asthmatic patient
e- ACEIs are recommended in pregnant women

Which of the following is NOT used in -62

: theophylline toxicity management
a-symptomatic control of seizures with benzodiazepine
b-activated charcoal to enhance elimination
c- b blocker for tachycardia
d-control vomiting with metoclopramide
e-methylphenidate to reduce excessive sedation
: Regarding the use of ACEIs -63
a-associated hypokalemia could be avoided by giving K-
supplement
b-effective in reducing proteinurea in diabetic patient
c-most common side effect is chronic dry cough
d-a good first line treatment for hypertensive diabetic
e-dose should be started low and triturated gradually upward in
need
:Regarding treatment of digoxin toxicity -64
a-verify time of last time
b-check Mg and K levels and correct if needed c-monitor ECG
d-no antidote for digoxin e-supportive care
 The antimalarial to avoid in glucose-6- -65
: phosphate dehydrogenase deficiency
a-primaquine b-quinine c-chloroguanide
HOW can prepare 100 ml of 12% MgCl by-66
?taking
a-12ml of MGCL dissolve in 100 ml water
b-12 mg of MGCL dissolve in 100 ml water
c-12ml of MGCL dissolve in 1000 ml water
d-90.5 ml of MGCL dissolve in 100 ml water
e-.95 ml of MGCL dissolve in 100 ml water
The following is NOT characteristic of-68
:solution
a-thermodynamically stable
b-composed of two or more component that exist in one phase
c-homogenous
d-the solvent and solute can be separated by filtration e-solute
doesn`t precipitate as time passes
Role of carbidopa in treatment of -69
.Parkinsonism
a- Serotonin reuptake b- dopamine agonist
c- Decrease dopamine in peripheral vessel
d- Dopamine antagonist e- 5HT1 antagonist
.Role of B-blockers in angina -70
.…………

When drug absorbed through -71

GIT then go to liver and
excreted this process called
a- first pass b- drug metabolism c-
drug distribution
All the following anti -72
inflammatory, analgesic effect
except
a-ibuprofen b- aspirin c- naprosyn d- sevredol
 which of the following need -73
filtration before IV infusion
a- mannitol b- dextrose 5% c- insulin
d- Suspension e- emulsion
azaleic acid used in-74
a-acne b- psoriasis c- myocardial infarction
which hormone are secreted -75
from posterior pituitary gland
a- oxytocin b- growth hormone c-
adrenocorticosteroid hormone
to increase duration of lidocaine -76
in anasethia
a- propranolol b- succinyl choline c-
epinephrine
................. -d- Atropine e
Drug absorption depend on -77
a- age b- sex c- dosage form
d- Drug state e- A and B
monitoring for dose in elderly-78
:patient
a- excretion in kidney decrease b- decrease in
liver enzymes function
c- reabsorption is high d- metabolism is high e-
A ,b
which of the following cause-79
metallic taste
a- captopril b- cimetidine c- metoformin
..................-d
 which of the following are -80
characteristic for Erythroped
a- not effective against G +ve cocci
b- not macrolide antibiotic
c- can increase GIT motility
d-can not used in pregnant women if needed
e- none of the above
which of the following are -81
:characteristic for Erythrosine
a-not effective against G+ve cocci
b- has amino glycoside antibiotic
c-decrease GIT motility
d-should not be used in pregnant woman if need

e-should be used in pregnant woman if need

the optimal size for ophthalmic-82
drops:- < 10μg
Amphetamine is used in: defect of -83
.awareness in the brain of children
if packaged are written for expiry-84
November 2006 it mean that can be
used till
a- 1 November b- 31 November
The mechanism of action of-85
Buspirone through a-5HT antagonistb-
GABA agonist
c-dopaminergic agonist d-dopaminergic
antagonist
Nitroglycerine introduces: -86
 .coronary vasodilatation
Omeprazole used to: decrease -87
.gastric acid secretion
which of the following has -88
aldosterone antagonist effect
a- amiloride b- furosemide c- spironolactone d-
hydrochlorothiazide

which of the following change-89

color of the urine to red nitrofurantoin ,
rifampicin
if patient take Gentamicin for a -90
time which of the following need
monitoring test
a- serum creatinine level b- liver enz. test
c- hemoglobin test d-...................... 91-which
of the following is antiarrythmic
-:class Ιa
a- lidocaine b- propranolol c- amiodarone d-
Quinidine
Class ΙΙ antiarrythmic drugs -92
-:produce its action through
a- decrease rate of phase 0 depolarization b-
increase phase 3 repolarization
c- suppress phase 4 depolarization d-
adrenergic receptor blocking
e- shorten action potential
antiarrythmic drug class Ιb -93
 -:produce its action through
a- decrease rate of phase 0 depolarization b-
increase phase 3 repolarization
c- decrease phase 4 depolarization d-
adrenergic receptor blocking
-:Chiral molecule mean -94
a-dipole moment b- solubility c- chelating prep.
.d-optical activity
lovastatin produce action-95
.through:- HMG-co reductase inhibitor
lisopril , zinopril or zestril is -96
-: found in
a-captopril b- fosinopril c- ramipril d-lisinopri
om″ is abbreviation for at ″ -97
.morning
ophthalmic prescription are -98
written through following ( gtt tod
-:Bid ) this mean
a- give one drop to right eye twice daily
b- give one drop to left eye twice daily
c- shake well and then give one drop to left eye
twice daily
d- shake well and then give one drop to right
.eye twice daily
tegretol is used in ttt of:- status-99
.epileptic, seizures
Streptokinase is used in ttt of:- -100
.pulmonary emboli
 all the following are antifungal-101
-:except
a- Nystatin b- Amphotericin c- Ketoconazole d-
.Gamciclovir
-:ceftazidime is -102
a- first generation cephalosporin b- second
generation cephalosporin
c- third generation cephalosporin d- fourth
generation cephalosporin
Bambuterol is used in:- treatment -103
.of asthma
Drugused in ttt of traveler -104
-:diarrhea
a-ampicillin b- amoxicillin c- co-trimoxazole d-
ciprofloxacin
Which organism are the cause -105
.of traveler diarrhea:- E-coli
.diazepam used in:- anxiety-106
solid to be reduced in size-107
before dissolving called:-
.disintegration

Benzodiazepine mechanism-108
through:- binding δ subunit of GABA-A
.receptor
Vinca alkaloids produce-109
anticancer drugs :- vincristine ,
.vinblastine . vindesine
 warfarin monitoring therapy -110
-:by
a- INR b- platelet count c- APTT d- lipid profile
in ovulation phase which-111
-: hormone is predominant
a-FSH b-LH c- progesterone d- progesterone
and LH
vencuronium is used as :--112
.skeletal muscle relaxant
most common process for-113
-:sterilization
a- filtration b- dry heat c- moist heat
which of the following need-114
serum level monitoring with
-:Quinidine
a-Digoxin b- albutrol c-ampicillin d-Diazoxide
-:side effect of epinephrine is -115
a- nausea , vomiting b- headache , constipation
c- hypoglycemic effect d- ischemic damage e-
skin rash
drug used for ttt of migraine-116
-:and HTN
a-clonidine b- minoxidil c- propranolol d-
hydralazin
can't be used as monotherapy -117
-:in mild HTN
a- hydralazine b- losartan c- pindolol
d- atenolol e- hydrochlorothiazide
 which of the following has -118
-:catharitic side effect
a- aluminum silicate b- magnesium sulphate c-
calcium sulphate
-:normal water can be used in-119
.a- parentral prep. b-ophthalmic prep
.c- oral susp. d-external prep
Ecothiophate mechanism -120
-:through
a-binding to muscarinic receptor b- cholinergic
antagonist
c- make complex with anticholinesterase and
inhibit its action
-:tetracaine is used as-121
a-opoid pain b- vitD metabolite
c- spinal anesthesia d- neuromuscular blocker
-:half life for first order kinetic-122
a- k b-1/k c- 2k d- 0.693k
adsorption are affected by the-123
-:following except
a- physical Rx b- chemical Rx c- irreversible
d- reversible e – B,C
Charcoal produce its action -124
-:through
a- adsorption
Digoxin used in ttt of CHF as -125
has:- + VE inotropic effect
PPM mean:- part per million OR -126
 million part
all are causes of 2ry HTN-127
-:except
a- phyochromocytoma b- cholinergic agent c-
..………… -sod. intake d

pt CHF take digoxin and-128

hydrochlorothiazide with ray
arthritis which of the following
-: drugs can be used
a-cortizone b-hydrocortisone c-fluticazone d-
prednisolone
if a drug has the same active-129
ingredient like other drug but not
contain the same inactive ingredient
-: this mean
a- Bioequivalent b-pharmaceutical equivalent c-
pharmaceutical alternative d- A,B
conc. of adrug is 7.5 mg in -130
teaspoonful
-:what will be conc. in 150 ml
mg________ 5ml 7.5
x? mg________ 150 ml
x mg=7.5x150/5 =225 mgْْْْْ
prep. contin coal tar 30 part -131
petroleum 15 part
adeq. to 150 partwhat conc. of coal
-:tar in 500 ml
 .part present in 195ml of prep 30
.x part present in 500ml of prep
so, conc. of coal tar in 500ml=30x500/195=76.9
part
which of the following is not-132
colloid
A-kerbs solution b- albumin 2% c- Dextran
d- Beta starch e- albumin 20%
.sildenafil is found in Viagra-133
Alteblase is used:- anticoagulant-134
salbutamol is used as:- -135
bronchodilator
podocodeine is used in dry-136
cough
which of the following not-137
-:used in emergency HTN
.…………-a- furosemide b- pindolol c- labetolol d
-: Doxorubicin side effect-138
a- cardiac toxicity b- nephrotoxicity
c- postural hypotension d- arrhythmia
which of the following -139
-:notused in ttt of asthma
a- B2 agonist b-B2 antagonist
Which of the following is -140
alkylating agent and anticancer
a-vinblastine b- cisplatin
c- Cyclophosphamide d- vicristine
 Very small molecule(1 part ) -141
soluble in 10,000 part of water
a- fairly soluble b- slightly soluble
C-immiscible d- miscible e- insoluble
benzoil not soluble in H2O but-142
soluble in benzene in 25◦ c
a- polar b- non polar c-soluble
d- insoluble e- slightly polar
one of the following is member -143
of phenothiazines group
prochlorperazine
primidone is prodrug for-144
.( antiepileptic drug )
Daily recommended dose for -145
folic acid 400-500 μg
Daily recommended dose for -146
-: vit. C in male
a-30mg/day b-50 mg/day c-90mg/day d-200
mg/day e- 400 mg/day
Daily recommended dose for -147
vit. C in female :- a-30mg/day b-50 mg/day
c-90mg/day d-200 mg/day e- 400 mg/day
max. daily dose for -148
paracetamol is( 4000 mg )
Ergot alkaloids is used as -149
antineoplastic
Buffering agent used in -150
ophthalmic drops to:- decrease irritation
to eye and increase stability
picosulphate is used as laxative-151
-:Digoxin toxicity increase with -152
a- renal failure b- hepatic pt
c- Asthmatic pt
All the following are side effect -153
-:of oral contraceptive except
a-hypertension b-weight gain
c- Hyperglycemia d- dizziness e- constipation
which of the following narcotics-154
-:not used today
a- morphine b- heroin
c- nicotine d- codeine
-:drug stored in the body in -155
a- fat b- muscle c- connective tissue d- lipid e-
protein
which of the following dosage-156
-:form are famous
a- solution, gel, oint. b- oint , gel , solution
c- oint, solution , gel e- solution , oint , gel
in case of hepatic or renal -157
failure which muscle relaxant is
-: recommended
Heparin can be monitored -158
-: through
a- APTT b- INR
-:Enixoparin is administrated-159
 a- IM b- IV
c- S.C. d- IV infusion

if drug protein binding -160

-:increased or decreased
↓ a- half life ↑ b- half life
c- side effect ↑ d- action ↑ e- a,b

161-3rd generation cephalosporin

-:has
a- G+ only b- G-ve only c- G+ve , G-ve
-: solubility enhanced through-162
a- reduce particle size b- increase surface area
c- increase particle size d- decrease surface
area
e- A&B
determination analysis of -163
solution depend on
a-nature of solute b- type of solution
c-analyzer d- a.b
when use liquid or oint. to-164
dissolve the solid it is called :-
levigation
phenytoin act on:- GABA -165
receptor166- NSAIDs produce action
-:through
decrease prostaglandin synthesis
which of the following not -167
-:characteristic of theophylline
 a- relaxation to brochial smooth muscle b-
increase cardiac contractility, CO
c- nausea , abdominal disturbance
e- convulsion d- sedation

what is drug of choice in ttt of -168

-:bronchospasm/asthma
a-salbutamol (albutrol ) b-theophylline c-
propranolol
d-esmolol e- quinidine
which of the following cause -169
-: depression
a- ampicillin b- reserpine

-:PRAVOC is used as -170

a- anticoagulant b- antiplatellet c- antibiotic
pound = 0.453 kg -171
sustained release dosage form -172
is used to
a-increase half life b- drug have low therapeutic
index
..……………………… -c
drug after metabolized in liver -173
-:it will become
a-polar b- non polar
c- lipophilic d- insoluble
 loading dose definition -174
in phase 1 in muscle -175
-:contraction occur
a-depolarization for k in
b- repolarization to ca out
-:half life of drug is 7 days HOW can taken -176
a- every day b- twice daily
c- twice weekly d- every week

diltiazim classified as : . Ca channel blocker -177

B carotine is precursop of : a-retinol b- thiamine c--178

riboflavin d- pyridoxine e- calcefirol

electrical property which produce impulses -179

: called
a-conduction b-automaticity c-velocity d- excitability
infusion of hypotonic solution in blood -180
: cause
a) shriniking of blood cell
b) hemolysis
c) hyperglycemia
d) hypoglycemia
e) b + d

infusion of hypertonic solution in blood -181

: cause
a) shriniking of blood cell
b) hemolysis
c) hyperglycemia
d) hypoglycemia
e) b + d
How gm of substance X must added to -182
2000 gm of 10% substance X solution in order to
‫ ؟‬prepare 25% of substance x solution
a) 10000
b) 400
c) 40
d) 10
e) 0.4
‫ عوزين نعرف هنضيف‬%10 ‫ جرام بتركيز‬2000 ‫الحل سهل إن شاء هللا هو عندنا مادة وزنها‬
%25 ‫ علشان يوصل التركيز بنسبة‬%100 ‫أد إيه من المادة دية والذي سوف يكون بتركيز‬
100% 15 )X(
25%

10% 75 )2000gm(
2000gm -------------75
X gm -------------15
So, X gm =15x2000/75 =400 gm
How gram needed from drug , if 0.1 gm in -183
ml , if 5 one tspfull doses contain 7.5 gm of drug
?
a) 0.0005
b) 0.5
c) 500
d) 1.5
e) 1500
denaturation will happened in body for -184
?which compounds
............-a-penicillin b- proteins c- lipid d-carbohydrate e
-:major metabolism proccess in GIT is -185
a-hydrolysis b- acetylation c- oxidation d-conjucation
dosage form of nitroglycren when used in -186
? malignant hypertension
a-IV b-IM c- S.C d- infusion e- transdermal
drug induced lupus like syndrom is -187
? associated with antihypertinsive
a-minixidil b- hydralazine c- dioxide d-nitroprusside Na e- acebutol

hypothirodism cause :- a-weight gain b- -188

...........-hypoglycemia c-low body temp d
ACE I mechanism of action as -189
??? antihypertension
inhibition of converting angiotensin I to angiotensin II -
About definition of first pass effect , it -190
-:increase with
a- increase rate of absorption b- increase biotransformation c-
increase pka
d- A&B
metal used in rheumatoid arthiritis : gold -191
: low density lipoprotein(LDL) act as -192
a-carrier cholesterol in plasma b- transport fatty acid c- good
.lipoprotien
-:true solutions another name is -193
a- homogenous b- heterogenous c-emultion d- suspension
abot ophthalmic preparation as single dose-194
-:which is false
..………-a-sterile b- purified c-should cotain preservative d
: most of drugs are-195
a-Weak electrolyte
b-Non electrlolyte
c-Non ionic
d-Strong electrolyte
e-B+ C
of substance X solution , 50% of 196-90%
substance X solution , how mixing both to give
? 80% of substance X solution
a- 3: 1 90% 30
b-1:3 80%
c-10:30 50% 10
d- 5: 9
B+C
 : antipseudomonas drug -197
a-metronidazole b-nystatin c- primaquine d-vancomycin

: digoxin differ from digitoxin-198

a-Half life
b-Excreted hepatically
d-Excreted unchanged in urine
?In digoxin induced arrythmia , what is not recommonded -199
a-stop digixin administration
b-phenytoin administration
c-give lidocaine
d-give digoxin immune fab
e-electrical cardio
: which is not asthma properties -200
a-Bronchodilator
b-Bronchospasm
c-Increase mucous secretion
d-Chest pain
: hormone excreted from adrenal cortex -201
a-Growth hormone
b-Primary product
c-mineral corticoids (eg, aldosterone)
d-glucocorticoids (eg, cortisolndrosterone)
e-weak androgens (eg, dehydroepiandrosterone)
immunosuppressant agent cannot used in -202
: organ transplantation
Predisolone
all of following are side effects of -203
: methotrixate except
a-Bone marrow depression
b-Alopecia
c-Nausea and vomiting
e-Drive sex gland
mechanism of action of antipsychotic -204
: drug
 Dopamine receptor inactivation
: ACE inhibitors are contraindicated in -205
bilateral renal artery stenosi
: about cardioglycosidic effect -206
a--ve inotropic
b-+ve inotropic
c-Hypertension
d-Tachycardia
e-Bradycardia

all factors affect on distribution of drug-207

: except
a-Tissue solubility
b-Protein binding
c-Molecular weight of drug
d-Type enzyme response of metabolism
: all factors affect on renal clearance except-208
a-Age
b-Sex
c-Both
d-Disease state
: ointment used for -209
a-Carrier of drug
b-Emollient
c-A&B
d-Increase absorption
e-Increase distribution
-: in hypodynamic shock treatment we used -210

a- dopamine
b- nicotine
c- aspirin
: acyclovir used to-211
Herbs simplex
lady take chronic warfarin , which is not -212
 true
a- avoid aspirin containing prepration
b-avoid doubling dose from herself
c-balanced food with green leaves to avoid thrombosis
d-if she pregnant, monitor INR to avoid DVT
e-take care about nasal bleeding
? which of following is least sedative action -213

a-Diazepam
b-Estazolam
c-Triazolam
d-Temazepam
?which drug has spasmolytic action -214
a-Resirpine
b-Amphetamine
-: desmopressine used in-215
nocturnal enuresis

pentophyllin used for : a-peripheral vasodilator -216

b-Hypertension
c-Cough suppressant Indications
Pentofyllin is indicated in diseases, causing disorders in the
peripheral perfusion, and in diabetes, atherosclerotic and
inflammatory disorders, including shank ulcers; gangrene;
diabetic angiopathy; intermittent claudication; Raynaud’s disease.
In acute disorders of the brain perfusion, including ischemic
stroke and resultant conditions. Acute disorders of the retinal
.blood supply
: mg \ L solution , according ppm 217-2
a-2 ppm
b-0.002 ppm
c-0.000002 ppm
: normal water used for -218
a-Eye preparption
b-Parentral preparation
c-Solution
d-Emultion
 e-External preparation
: ceftazidime -219
3rd generation
? about amino glycoside , which is not true-220
a-Has gram –ve activity
b-Less toxicity
c-Narrow therapeutic
d-Compatible with other drug
e-Usually IV , IM
-: about nor epinephrinenot true -221
a-increaser B.P
b-vasoconstrictive
c-used in cardiogenic shock
d-effective orally
e-S.C
-: PHARMACOKINETIC CONSTANT -222
a-Zero order
b-1st order
c-2nd order
d-Mixed order
e-A + B

Which of the following is NOT predinsolone -223

? side effect
a-cataract b-hypoglycemia
c-skeletal muscle weakness d-sodium retention
e-lowered resistance to infections
When concidering drug therapy for -224
?hypertention , which is true
a-combination of drugs always preferred
b-hydralazine is first line therapy in young hypertension
c-furosemide should be administrated before meal to improve
absorption
d-b-blokers should be avoided in asthmatic patient
e- ACEIs are recommended in pregnant women
solutions are better than solid dosage form-225
 :coz
a-Accurate dose
b-Easy to handle
c-More stable
d-Faster action
e-B + C
One of following NOT used to cover bitter -226
-:taste
a-Film coat
b-Enteric coat
c-Grinding of tablet
which of following tricyclic antidepressant-227
?is tertiary amine
Amitriptyline
? antihypertensive used in pregnancy -228
Alpha Methyldopa
drug used for peptic ulcer ?( Losec)-229
drug infusion rate is 2mg\kg\hr , infused for -230
?12 hours , for 70kg patient. what is total dose
1680 mg=)2x70x12(
-:mean )GMP (-231
a-Good Manufactor Protocol
b-Good Manu factor Product
c-General Manufactor Protocol
d-General Manufactor Product
how many gm of water add to 5% KCL soln-232
?to make 180 gm of solution(w\w)
5gm--------------100
Xgm--------------180
X= 5x180/100=9 gm
-:So, the amount of water is
gm 171= 9 - 180
according to steril method which of the -233
-:following is false about filtteration
 able to filtter viscous substance ‫عليك أن تختار‬

when you know the preservative used with -234

-:anti biotic is not suitable you make
a- use another one is suitable
b- add another to increase it is activity
c- use tow or more preservative may increase the activity and may
become suitable
d- a+c
deltiazem & nifedipine &flocdipine act as -235
block Ca to intracellular & increase metabolism from storage site -
-:All of this affect rate of absorption except -236
a- chemical stability b- PH
c-protein binding d- A&B e- B&C
. Doxorubicin side effect is tissue necrosis-237
Cholystyramin resin act by :- anion exchange-238
The conc. Of ionized & unionized calculated by-239
(Henderson hasselbachk equation)
-:Light sensitive drug should be storage in -240
a-Colorless glass b-Colorless plastic c-Amber glass d-Amber plastic e-Light resistant
container
.Electromagnetic rays :- gamma rays, x-rays-241

Cyclophosphamide (side effects) Appetite loss;-242

absence of menstrual periods; color change in skin; diarrhea;
general unwell feeling; hair loss; nausea; skin rash; stomach
.discomfort or pain; texture change in nails; vomiting; weakness

Isoproterenol( Isoprenaline )-243

.adrenergic agonist medication
.Coal tar uses in (psoriasis)-244
The most common reaction catalysed by-245
cytochrome P450 is a monooxygenase
The most common phase I reaction is-246
 oxidation
Which Of The Following NOT Used In Peptic -247
-: Ulcer
a-Tetracycline b- Itraconazole
c-Metronidazole d-bismuth subsalicylate
e-clarithromycin
Which Of The Following act as alpha 1-248
-: blocker
a- hydrazyline b-terazocine
c-propranolol d-captopril
e- clonidine
comparison between sterile water &water-249
-:for injection
a- pyrogen free b-free from sod. Chloride
c- Isotonic d-free from bacteria
e- A&C
-: Qunidine has similar action to -250
a-procainamide b- lidocaine
c-propranolol d- hydralzyine
Which of the following drug has side effect -251
: lupus like syndrome
a- lidocaine b-minoxdile
c- procainamide d-hydrochlorothiazide
.Over dose of digoxine we use:-(anti dote FAB Fragment ) -252

-:Ampicilline has similar action of -253

a- tetracycline b-cephalexin
c-cloramphinicol d-amikacine
-:Cephalosporin act as -254
a-Inhibitors of cell membrane function
b-inhibitors nucleic acid synthesis
c-Inhibitors of protein synthesis
d-Inhibitors of cell wall synthesis
e-Inhibitors of metabolism
Antibiotic used as anti pseudomonas -255
 -:aeruginosa
a- Meropenem b- Bacitracin
c- Amoxicillin d- penicillin V
Antipseudomonal Antibiotic :- -256
(piperacillin,carbencillin,ticarcillin )
Auxliar of label are written on box contain-257
-:CO-TRIMETHOXAZOLE all is true except
a-shake the bottle before use
b-suspension
c-freezing of drug
d-keep out of reach of children
Ipratropium bromide :-(Anti muscarinic bronchodilator ) -258

-: keep in cool place means-259

a-in refrigerator
b-in freezing
*c-at 10-20 c
d-A&C
e-A&B
260-5mlof injection that conc. 0.4% calculate the amount of
?drug
a-0.2mg c-200mg
b-2mg d-2000mg
e-20mg
How need prepare benzacainamid conc. 1:1000,30cc of -261
?benzocainamid solution
a-30 b-50 c-80
d-100 e-130

Amphetamine act as :- (INDIRECT-ACTING-262

ADRENERGIC AGONIST)
-: Increase plasma HDL Level-263
) Reduce Risk of Atherosclerosis(
Waraferin act as:- (inhibited blood clot )-264
 -:cyclophosphamide side effect is-265
……………,a-blared vision
b-vomiting .alopecia
c-bone marrow depression
d-A&B
e-B&C
.…………………-:Action of alpha 1 receptor-266
which of the drug used in open angel-267
-:glaucoma
) pilocarpine(
All (ACEIs) are prodrug except:--268
CAPTOPRIL (prototype)
-:Opthalmic prep. Proffered to be taken-269
.a-solu. > susp. > oint
.b-solu. > oint > susp
c-susp. > solu. >oint
d-any dosage form can be used

digoxin toxicity precipitated by :--270

(Hypokalemia )
which of the following drug has anti-271
inflammatory effect :- (Ibuprofen )
Digitoxine effect in electro cardio chart-272
-:(ECG)
a-prolong P.R b-shorten P.R
c- T. shaped d-prolong B.R
Digitoxine toxicityeffect in electro cardio-273
-:chart (ECG)
a-prolong P.R b-shorten P.R
c- T. shaped d-prolong B.R

Relative bioequivalent compared between-274

-: std. drug &test drug acc. To
 AUC (Area Under the Carve )
Cephalaexine is :-first generation-275
.cephalosporin
-: After the myocardial infraction we use-276
Anti platelet (aspirin)
KI solu. Has 0.5mg/ml dissolve in 30ml-277277
water calculate the amount of KI in the solu. ?
(15mg)
Omeprazol used for :- peptic ulcer-278
-: Alph 2 Agonist-279
Decrease blood pressure
The equation that determine the acid & base-280
degree is:- (BRONESTED EQUATION )
. ISONIAZIDE used in TIBERCULOSIS-281
-:mechanism of action of Buspirone on-282
Serotonin (5HT2a) receptor
All these cases not cure with thiazides-283
-:except
a-hypernatrimia b-Hyperglycemia
c-Hypokalaemia d-Hyeruriceamia
e-Hyponatrimia
Which of the following drug of choice for-284
-:Myxodema
.Thyroxin sod-: ) Hypothyroidism(
Vit. A daily dose is 30,000-50,000 IU for the-285
correction of the deficiency &for therapy from
.100,000-200,000 IU/day

All these cases not cure with thiazides -286

-:except
 a-hypercalcemia b-Hypoglycemia
c-Hypokalaemia d-Hyeruriceamia
e-Hyponatrimia
.Zidovudine is used for HIV-287
Bisacodyl used as :- Laxative-288
POM mean:- prescription only medicine-289
-: The con. Of the drug on exp. Date is-290
From 90-110%
-: Surfactant not used orally-291
Sod. Lauryl Sulphate
The drug transfer through the cell-292
-: membrane by
a-Aqueous diffusion b-Osmotic pressure
c-Lipid dissolve d-Passive diffusion
e-NON of the above
Calcipotriol is indicated for :- PSORIASIS -293
which of the following make water-294
-:retention
)Indomethazine(
Nitroglycerin is :- (Vasodilatation of-295
.coronary artery)
Anti psychotic act as :- (Dopaminergic-296
Antagonist )
Vit, K is antagonist of :- WARAFARINE -297
protamine sulphate is anti dote of:--298
HEPARINE
-: Prmethazine used as-299
Anti histaminic (pruritus , cough ,anti emetic)

-: Which Of The Following act as alpha 1 blocker -300

 .)PRAZOCIN (
Whate The Specific gravity of substance-301
& has Weight=Y
? The volume is X
The Specific gravity =Density of the substance/Density of water
/volume(X)/1
So, the sp. gravity of sub. =weight (Y)
So, the sp. gravity of sub. =Y/X
-:ESMOLO is-302
Short acting B- blocker used in emergency in
. Acute arrhythmia as IV administration