The Pathology Company
Leica RM2245
                        The Manual Microtome with High-Precision
                        Motorized Specimen Feed
2
The Leica RM2245 –
Efficiency Goes Hand in Hand with Comfort
The Leica RM2245 semi-motorized rotary microtome                maximum section reproducibility. operator fatigue is reduced
represents the perfect combination of economic efficiency       through the use of the patented spring system, which
and user comfort. It is the instrument of choice for clinical   eliminates the need for a heavy counter balance weight in
histology and histopathology applications, as well as for       the handwheel. Enhanced user comfort results in maximum
research applications.                                          workplace efficiency and high specimen throughput.
The Leica RM2245 is designed to meet the many requirements With the Leica RM2245 there is a choice between the
of modern laboratories. This task is fulfilled without          conventional manual sectioning method of full handwheel
compromise by combining proven technology and exemplary         rotation and the “rocking mode.” In rocking mode, the
safety standards with functionality and ergonomic design.       handwheel is only turned back and forth over a short
                                                                distance. Every change in rotation direction is automatically
Manual sectioning is enhanced by the high-precision motorized translated into a specimen feed or retraction movement.
specimen feed, which results in efficient operation with
3
4
The Useful Details Show a Great Design
Concept
Comfortable operation                        Safety during sectioning                      Ergonomics and user safety
All functions are controlled via a compact, Safety is ensured by the integrated,           The smooth-running safety hand-wheel
space-saving control panel with areas        red finger protection guard of the knife      has an ergonomically shaped handle. A
in contrasting colors and touch-sensitive    holder E that uniquely shields the            hand-wheel locking device for one-thumb
buttons that allow ‘blind operation.‘ Panel blade edge. When used correctly the            operation locks the specimen head in the
inclination is adjustable, and the panel     integrated finger protection guard            uppermost position, which is ideal for
can be positioned either on the left or      rules out potential injuries.                 changing the specimen and/or blade. A
right side of the instrument.                                                              second locking mechanism on the
                                                                                           microtome base allows locking the object
                                                                                           head in any position.
Spacious, magnetized section waste tray      Unobstructed work area and stability          Easy to clean
The spacious section waste tray reliably     To provide improved access to the cutting     Due to the rounded shape of the Leica
collects sectioning debris. It is safely held area, several clamping levers that are not   RM2245 instrument’s one piece housing,
in position by magnets, yet is easily        routinely used have been replaced by          section waste is easily removed.
removable for emptying and cleaning.         hidden clamping devices without               The integrated slot cover prevents debris
                                             compromising standard setting options.        from entering the internal mechanisms of
                                             Maximum rigidity and stability are provided the microtome.
                                             by the optimized microtome base plate.
                                                                                                                                        5
                                                                                           Well thought-out and proven
                                                                                           • The Leica-Patented Force
                                                                                             Compensation System: for extremely
                                                                                             smooth manual handwheel operation.
                                                                                           • The Precision Micrometer Feed
                                                                                             System: from 0.5 µm to 100 µm in
                                                                                             sectioning mode and 1 µm to 600 µm
                                                                                             in trimming mode via stepper motor.
                                                                                           • The Leica Control Panel Concept:
                                                                                             separate and intuitive control panel
                                                                                             for instrument settings and
                                                                                             communication display integrated in
                                                                                             the instrument housing at eye level.
                                                                                           • Accessories: a wide range of blade or
                                                                                             knife holders and specimen holders is
                                                                                             available for a variety of applications.
Precision specimen orientation with clear    Lateral knife holder adjustment               Cool storage of specimen blocks
zero reference point
                                             The entire width of the microtome blade       A cooling plate with thermo element
This orientation mechanism sets new          can be used without having to release         can be used for cold storage of specimen
standards of precision and is very easy      the blade clamping mechanism. Using the       blocks either on top or on either side of
to operate. An important detail:             entire knife edge saves costs, especially     the microtome.
Calibrated controls make it easy to adjust   in laboratories with high specimen
a specimen to an exact zero position         throughput. Three predefined stop positions
indicated by red pins or a measurable        (left, center, right) correspond to the
variable on the X/Y axis for re-cuts.        width of a standard histology cassette.
6
Technical Specifications
                                                                         Electric coarse feed        300 µm/s and 900 µm/s
Section thickness                                                        Maximum specimen
Setting range                     0.5 – 100 µm                           size (L x H x W)            50 x 60 x 40 mm
Setting values                    from 0.5 – 5 µm in 0.5 µm increments   Specimen orientation        horizental: 8°, vertical: 8°
                                  from 5 – 20 µm in 1 µm increments      Nominal supply voltages 100/120/230/240 V AC ± 10%
                                  from 20 – 60 µm in 5 µm increments     Nominal frequency           50/60 Hz
                                  from 60 – 100 µm in 10 µm increments Power draw                    70 VA
Trimming section                                                         Dimensions basic instrument
thickness setting range 1 – 600 µm                                       Width (incl. handwheel)     413 mm
Object feed                       28 mm ± 1 mm, feed motion              Depth (incl. waste tray)    618 mm
                                  via step motor
                                                                         Height (with storage
Vertical specimen                                                        area on cover)              305 mm
stroke                            70 mm
                                                                       Weight (without
Sectioning modes                  2 manual modes (conventional full    accessories):                 approx. 37 kg (87 Ibs)
                                  handwheel rotation and rocking mode)
Specimen retraction               5 – 100 µm in 5 µm increments,
                                                                         Dimensions control panel
                                  can be turned off
                                                                         WxDxH                       94 x 164 x 50 mm
A wide range of accessories is available upon request.                   Weight                      approx. 0.450 kg (1Ib)
Technical specifications are subject to change without notice.
Certifications: CE, c-CSA-us
The Leica RM2245 features at a glance
• Precision specimen orientation with zero point reference               • Precise knife holder lateral movement
• Compact, ergonomic overall design                                      • User safety integrated into overall design
• Section thickness totalizer and section counter                        • Smooth-running handwheel with integrated quick-lock
• Easy alternation between trimming and sectioning function                mechanism
• Two motorized forward and backward specimen coarse feed                • Ergonomically optimized handwheel handle
    speeds                                                               • Communication display integrated in instrument housing
• Programmable specimen retraction                                       • Enclosed micrometer mechanism
• Low-maintenance cross roller bearings                                  • Spacious magnetized section waste tray
• Knife holder concept for disposable blades, with finger guard          • Intuitive control panel
    in contrasting color                                                 • Wide range of accessories
                                               7
Consistant
sharpness
and durability
for quality
sections
To help you cut the best possible sections,
Leica Biosystems has a broad range of
blades and knives for microtomes and
cryostats. This range consists of both high
and low profile disposable microtome
blades to provide precision cutting for
all tissue types, including difficult tissue
types such as uterus.
Whether for dense or soft tissue, frozen or
routine sectioning, biopsies or large tissue
samples, Leica Biosystems has a range of
blades to meet your sectioning needs.
LeicaBiosystems.com
                                                                                TOTAL PARAFFIN SECTIONING SOLUTIONS
                                                                                Leica Surgipath Microtome Blades
                                                                                Achieve quality sections from our broad range of finely-engineered
                                                                                microtome blades.
                                                                                Leica Surgipath Slides
                                                                                With many color and adhesive options you’re sure to find the ideal slide
                                                                                for your application.
                                                                                Leica HI1210 Water Bath for Paraffin Sections
                                                                                A flattening bath for paraffin sections and a water bath maintaining
                                                                                specimens and solutions at required temperatures for IHC applications.
                                                                                Leica HI1220 Flattening Table for Paraffin Sections
                                                                                A flattening table with a large jet black aluminum work surface to
                                                                                provide high thermal conductivity rates and outstanding resistance
                                                                                to mechanical manipulations.
LEICA biosystems
Leica Biosystems is a global leader in workflow solutions and automation,             Leica Biosystems brings
striving to advance cancer diagnostics to improve patients’ lives. Leica              together products,
Biosystems provides anatomic pathology laboratories and researchers a
                                                                                      quality and support.
comprehensive product range for each step in the pathology process,
from sample preparation and staining to imaging and reporting. Our
                                                                                      Offering a complete solution
easy-to-use and consistently reliable offerings help improve workflow                 that helps you advance workflows, enhance
efficiency and diagnostic confidence. The company is represented in over              diagnostic clarity and deliver what really
100 countries and is headquartered in Nussloch, Germany.                              matters – better patient care.
Leica Biosystems – an international company with a strong network of
worldwide customer service.
North America Sales and Customer Support
North America                                        800 248 0123
Asia/Pacific Sales and Customer Support
Australia                                            1800 625 286
China                                                +85 2 2564 6699
Japan                                                +81 3 5421 2804
South Korea                                          +82 2 3416 4500
New Zealand                                          0800 400 589
Singapore                                            +65 6779 7823
Europe Sales and Customer Support
                                                                                95.11550 Rev D - 7/2014 ∙ Copyright © by Leica Biosystems, Nussloch, Germany, 2014.
For detailed contact information about European sales offices or distributors   Subject to modifications.
please visit our website.                                                       LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.