Ebise Proposal
Ebise Proposal
NAME ID NO
1.EBISE BIRATU ……………………………………………………………………….29565
2. BETHLEM FIKADU ………………………………………………………………….
3. ASTER FARAJA ……………………………………………………………………..
APRIL: 2024,
NEKEMTE- ETHIOPIA
1
Acknowledgements
My sincere thanks go to our advisors…and Professor ……for their unreserved assistance and timely
guidance and comments until the completion of this thesis.
Our thanks should also go to Dr. …. who took his time to read my proposal and first draft and
provided me valuable advice and comment.
All staffs of Department of Community Health Wallaga University deserve our deepest appreciation
for their cooperation.
Our thanks also go to my friends for their appreciable moral support and advice.
We also thank all staffs of Bedelle health office and all supervisors and data collectors and all
mothers who participated in this study.
Special thanks and appreciation also should go to our friends who had suffered by keeping quiet while
we were in study.
Last but not least we are highly indebted to our parents who had taken the whole responsibility
managing our life during our learning process.
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Table of Contents
Contents Pages
Acknowledgements........................................................................................................................2
List of abbreviations......................................................................................................................5
ABSTRACT....................................................................................................................................6
CHAPTER ONE............................................................................................................................9
1. Introduction............................................................................................................................9
CHAPTER TWO.........................................................................................................................14
2.5. Infections............................................................................................................................17
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2.6. Risk factors for neonatal tetanus in developing countries relate to:............................17
CHAPTER THREE.....................................................................................................................19
3. Introduction..........................................................................................................................19
4. Sampling procedures...........................................................................................................21
5. Operational definitions........................................................................................................22
5.5 Abortion..............................................................................................................................22
Reference...................................................................................................................................24
List of Tables
iii
Table 1 Socio demographic characteristics of mothers by place of delivery in General HospitalL ,
Murch. 2024
Table 2 Pregnancy outcomes of mothers by delivery place in General Hospitall , Murch.2024.
Table 3 Obstetric history of mothers by place of delivery in General Hospitall ,Murch. 2024
Table 4 Selected characteristics of mothers in General Hospitall Murch..2024
Table 5 Selected characteristics of newborns in General Hospitall Murch. 2024
Table 6 Socio demographic factors associated with perinatal mortality in General Hospitall ,
Murch.2024
Table 7 Obstetric history of mothers associated with perinatal mortality in General Hospitall ,
Murch.2024
Table 8 Socio demographic factors associated with neonatal mortality General Hospitall , Murch..
2024
Table 9 Socio demographic factors associated with neonatal mortality in General Hospitall . Murch.
2024.
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List of abbreviations
PMR… … … … … … … … … … . … Perinatal Mortality Rate
NNM…..................................................Neonatal Mortality Rate
SBR………………………………..….…Stillbirth Rate
ENMR …………………………………...Early Neonatal Mortality Rate
LNMR……………………………….…..Late Neonatal Mortality Rate
ANC…………………………………….Antenatal Care
TBA…………………………………….Traditional Birth Attendant
TTBA…………………………..………Trained Traditional Birth attendant
EOC……………………………....…….Emergency Obstetric Care
CPD…………………………….....……Cephalous-Pelvic Disproportion
TTV…………………….………….…...Tetanus Toxoid Vaccination
IMR…………………….…….….…..….Infant Mortality Rate LB
OR……………………………..….…….Odds Ratio
COR………………………………..……Crude Odds Ratio
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ABSTRACT
The commonly used pregnancy outcome indicators in developing countries are maternal mortality,
abortion, perinatal, neonatal mortality, low birth weight and preterm births. About eight million
perinatal deaths are reported annually in the world of which 40-60% is neonatal mortality and
almost all are in developing countries. Many hospital based studies were conducted on those
problems, while community based are very few. Therefore this community based cross sectional
comparative study was conducted to assess the pregnancy outcome with emphasis on perinatal and
neonatal mortality by delivery place and its associated factors in Beddelle town. The study was
conducted between November 2024 and March 2024. A total of 1462 mothers who had children or
had been pregnant for the last five years were participated in the study.Pre tested standardized
questionnaires were used to obtain information on socio demographic, obstetric history and the
condition of the new born and mothers during labor and neonatal period. Analyses were made using
EP INFO 4.6 statistical package and SPSS version 10. In the study the following findings were found:
High perinatal mortality rate of 73/1000 live births with 38/1000 and 35/1000 live births being
at home and in health institutions respectively. High neonatal mortality rate of 47/1000 live births
with 28/1000 and 19/1000 live births at home and in health institutions respectively.Mothers who
had 2-4 parity had more risk to perinatal mortality than primi Para mothers. (AOR 5.15, 95%CI 1.54,
17.23) and mothers who had 5+ parity had more risk to perinatal mortality than primi Para mothers.
(AOR 4.38, 95%CI 0.65, 29.40) In this study it is found that very small and small (mother’s
perceptions birth weight) neonates have more risk to neonatal mortality than neonates who had
normal birth weight when they were born(AOR 3.61, 95%CI 1.75, 7.43) and also term babies had less
risk to perinatal and neonatal mortality than babies born preterm it is statistically significant when it
is entered into logistic regression model(AOR 0.28, 95%CI 0.11, 0.70) and (AOR 0.28, 95%CI 0.12,
0.63) respectively.Mothers whose income were <300 birr per month had more risk to neonatal
mortality than mothers whose income were >601 birr per month. (AOR 4.64, 95%CI 1.53, 14.01) and
mothers whose income were 301-600 birr per month had more risk to neonatal mortality than mothers
whose income were >601 birr per month. (AOR; 4.29, 95%CI 1.27, 14.50). Based on the above
findings of the study the following recommendations were made. Strengthening of the MCH/FP care
unit at each level and encourage mothers to use FP services and improve quality of care ,
establishing and utilization of emergency obstetric care services with special emphasis of neonatal
care and give special attention to empower of mothers and improve economic status and educational
level of women.
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CHAPTER ONE
1. Introduction
This chapter includes background of the study, statement of the problem, objectives of the study, research
questions, significance of the study, scope of the Study, delimitation of the study, limitation of the study and
finally organization of the paper.
Large proportions of infant deaths and disabilities have their origin in the perinatal period and are
primarily determined by the condition of pregnant women and the circumstances of the birth rather
than by the condition of the child itself. The underlined direct causes of these deaths relate to the
health and nutritional status of the woman during pregnancy, the quality of care during pregnancy and
delivery and the immediate care of the newborn. Maternal health care, female literacy, family
planning and social support for women are both as a right and necessity for women themselves and to
ensure the safe birth and healthy survival of the newborn.
Neonatal deaths are generally associated with elements linked to maternal care during pregnancy and
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delivery while socio-environmental factors become more important determinants of infant survival
during the post neonatal period. Despite wide recognition that in rural Africa pregnancy is a
hazardous time for both mother and child, there are few data quantifying the degree of risk. Most of
the information about maternal and pre/neonatal mortality is related to hospital-based surveys.
Although in many rural areas, few women deliver in hospital or health center, on the other hand, even
when there have been complications during the pregnancy many women deliver at home, therefore
most stillbirths and early neonatal deaths occur at home and information on the outcome of
pregnancies can be obtained only by asking these women about their past obstetric history and by
observations.
Perinatal and neonatal mortality is influenced by several biologic, environmental, socio demographic
and socio economic factors. Improvements in prenatal, neonatal and obstetric care, good social
conditions, the better environment and the demographic characteristics of mothers have contributed
for the declining of perinatal mortality in the developed countries. Perinatal and neonatal mortality
can differ by rural, urban and other locations even with in large demographic Survey.
Neonatal survival rate as a measure of outcome is regularly used for medical audit purposes. In Kenya
neonatal survival rate is still useful as an audit tool since the projected mortality rates are probably
still very high. Its knowledge will help determined the broad developmental strategies to adopt for
improving the provision of medical care. Important component efforts to reduce the health risk of
mothers and children are to increase the proportion of babies delivered under the supervision of
trained birth attendant. Proper medical attention and hygienic conditions during delivery can reduce
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risk of complication and infections that may cause death or serious illness to either the mother or the
baby or both. It is impossible to change socio-economic characteristic and cultural reproductive
patterns overnight, good data collection will help to assess need and good coordinated maternity
service can provide short-term improvements. The maternity services need to embrace: Primary care,
which its emphasis on village & rural obstetric care including the teaching of traditional birth
attendants, the training of midwives, doctors and established high-risk hospital care units.
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1.7. Delimitation of the study
Furthermore, the study is delimited to one sub-city again due to time and financial constraint.
However, since administration procedures are the same in the entire city, the result that is obtained
taking case of these specific sub-cities could reflect the situation of
assessment of pregnancy outcome with emphasis on perinatal and neonatal mortality in all over
the city, under normal circumstances.
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CHAPTER TWO
2.1. LITRATURE REVIEW
About eight million perinatal deaths are reported annually in the world almost all 98.0% is in
developing countries, and nearly five million neonates die each year in the world of which 96% are in
developing countries.
Perinatal and neonatal deaths are the most significant contributors to infant’s mortality and reduced
life expectancy. Perinatal mortality in the developed world indicates a rate of 10/1000 live births (LB)
or less, while in developing countries perinatal mortality range from 35/1000 LB to 100/1000 LB.
Des Gupta ET. Al. in India found that perinatal mortality (in medical college hospital) is 67. 2/1000
LB and 29. 3% was early neonatal deaths.
It is estimated that neonatal deaths in developing countries can account for nearly 50- 60% of all
infants’ deaths.
In most developing countries approximately half the infant deaths occur in the first months of life
(that is the neonatal period). In some developing countries infant mortality rate ranging between 32.8
and 135.0 per 1000 live births. Neonatal death account for between 42 and 63 % of infant mortality
and neonatal mortality can differ by rural, urban and other locations even with in large demographic
survey.
In Ethiopian context studies about perinatal and neonatal mortality have been conducted since 1970s.
Naeye et al found the perinatal mortality at Tikur Anbessa Hospital 1019 post-partum examination
were performed for perinatal disease. The overall PNM rate was /1000LB. The ratio of stillbirth
(SB) to neonatal deaths was 2.7:1 indicating that maternal factors were dominant in causing the
deaths. One third of the deaths were due to amniotic fluid infections, 15% to obstructed labor, 8%
abruption placenta, & the rest more than 20% were other specific disorder. The arrival of mothers at
delivery center earlier in labor & improved obstetrical practices would probably have saved some
infants in the categories.
Frost .O in 1984 in Black Lion Hospital (BLH) conducted a study, which showed that: Stillbirth Rate
(SBR) 52.6 /1000LB, PNM 8.6/ 1000LB and MMR 7.8 /1000LB
Age, parity and socio- economic status of the mother are classical features that epidemiologists
associate with perinatal death.(10)
Frost .O in 1984 in Black Lion Hospital (BLH) conducted a study, which showed that: Stillbirth Rate
6
(SBR) 52.6 /1000LB, PNM 8.6/ 1000LB and MMR 7.8 /1000LB
Age, parity and socio- economic status of the mother are classical features that epidemiologists
associate with perinatal death. (10)
Sahile Mariam Y. and Berhane Y. Studied neonatal mortality rate of 1334 singleton neonates born at
three Addis Ababa hospitals prospectively followed during the neonatal period. They found the
neonatal mortality rate to be 71.9/1000 LB. with early and late NMR of 50.9 and 20.9/1000 L.B.
respectively. The main risk factors for perinatal mortality were being low birth weigh and
prematurity.(16)
A Prospective community based study on pregnant women in rural community of south central
Ethiopia was conducted and revealed that still birth 19 per 1000 live births, Perinatal mortality
45 per 1000 live births and neonatal mortality 37 per 1000 live births. (17)
In south western Ethiopia at Jimma teaching institute hospital a study showed that perinatal
mortality rate is 138.9 per 1000 live births which is the highest in the world (12)
7
mortalities. (3, 19)
8
or stillbirth, low birth weight, early and late neonatal mortalities
2.5. Infections
It is one of the leading causes of perinatal and neonatal mortality in developing countries. Based on
hospital data suggest that nearly 7-54% of early neonatal deaths and 30-73% of late neonatal deaths
are associated with infections, (1.5-2 million neonatal deaths per year).
According to W.H.O 30-40% of all neonatal deaths are explained by neonatal infections. Infections
can either be transmitted from mother before birth or would begin after birth.
Rubella and Syphilis are commonly identified as the two important infections occurring before birth
in developing countries. However, in several developed and African countries infections prior birth is
one of the important determinants of premature and low birth weight babies.
The unhygienic circumstances of delivery and the associated environment are exposed to be a major
cause of after birth infections. The major causes of death due to neonatal infections are tetanus,
respiratory infections, diarrhea and sepsis.
WHO has estimated that approximately 400,000 cases of neonatal tetanus occur annually. The vast
majority of deaths are in developing countries resulting 340,000 neonatal tetanus deaths annually.
2.6. Risk factors for neonatal tetanus in developing countries relate to:
Lack of immunization of mothers with tetanus toxoid
Unhygienic delivery
Unhygienic cord care during the first week of the life (11, 18)
2.7. Malaria in pregnancy
Pregnant women have an enhanced risk of malaria in regions where transmission rates are high. In
low transmission areas, the entire population is at risk, but pregnant women are especially vulnerable,
particularly during epidemics. Pregnant women may be 1.6-4.9 times more likely to be admitted for
malaria than other adults in low transmission areas. These results show that malaria is an important
cause of malarial illness, poor pregnancy outcome and deaths.
The researchers recommended that: to apply the available control measures, such as insecticide
treated bed nets, in epidemic situations.
Investigate the usefulness of providing preventative anti-malarial drug treatment during pregnancy in
low transmissions areas.
2.8. Rationale of the study
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Perinatal, neonatal and infant mortality rates are the most important vital statistics used to assess
maternal and child health program. They are indicator of the quality of antenatal care, medical
services and general health services to the mother and the children.
Follow up studies based on institutional deliveries are important to detect the magnitude of the
problem, however a significant proportion of deaths might occur outside health care facilities and
community based studies are limited. Therefore it is very important to initiate a study on perinatal and
neonatal mortalities that include home and institution deliveries.
Ethiopia like the majority of other developing countries has a problem of vital registration system.
Moreover there are no attempts to date to estimate the problems in the community where unhygienic
home deliveries are widely practiced.
At present where the health policy of Ethiopia emphasizes the government commitment to improve
the health status of the population in general, women and children in particular. This study is intended
to provide base line information for planners and decision makers.
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CHAPTER THREE
3. Introduction
This research work is a descriptive study to analyzing the assessment of pregnancy outcome with emphasi
s on perinatal and neonatal mortality in General Hospitall and the major constraints and the cause of the
perinatal and neonatal mortality in Beddelle Town. To analyze the above objective, the following research
design, questionnaire design, data collection procedure, sampling strategy, data processing and analysis were
used.
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4. Sampling procedures
Beddelle has two higher that consist of two kebeles each. From each higher one kebele was randomly
selected using lottery method. Census method was used to collect data from randomly selected two
kebeles.
A total of 1427 households were visited. From each household one mother who had child less than 5
years old or mother who had been pregnant for the past 5 years were interviewed. If there were two
mothers in a household one was selected using lottery method. A total of 1414 mothers participated in
the study. When respondents were not found at home for some reasons, at least three attempts were
made to interview each respondent before skipping.
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data collection for a particular kebele was completed, supervisors made a thorough check up before
leaving that kebeles.
5. Operational definitions
5.1. Perinatal mortality-
It is fetal death starting from 28 weeks of gestational age and the death of new born in the first week
of life, which comprises late fetal and early neonatal death.
5.5 Abortion
The termination of the process of gestation after the time when the zygote attaches itself to the uterine
wall or 14 days after conception, but before the fetus is possibly capable of surviving on its own or 28
weeks from conception.
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6. TIME AND BUDGET SCHUDULE
Work Plan
Description activities December January February March April
Title approval
Review of literature
Questionnaire preparation
Data collection
Data entry, editing & coding
Data analysis
Report writing
First draft thesis submission
Final thesis defense
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