PHARMACOLOGICAL SHEET

GENERIC Ceftriaxone 2gr TRADENAME Acantex; Bioteral; GROUP TO WHICH Anti-infective

NAME Ceftriaz IT BELONGS therapeutics
MECHANISM PHARMACOKINETI INDICATIONS CONTRAINDICATIONS ADVERSE NURSING CARE
OF ACTION CS AND WARNINGS EFFECTS
Ceftriaxone is CONTRAINDICATIONS *Diarrhea, *nausea -Check if the
administered -Hypersensitivity to patient has
parenterally because it cephalosporins or *Vomiting, diarrhea after
is not absorbed through administration of
the digestive tract. After *Sepsis penicillins. *Stomatitis
the medication.
Broad- an intramuscular dose,
spectrum, long- maximum serum *Meningitis -Newborns or *Glossitis
concentrations occur -Check if you
acting premature babies at *leukopenia,
between 1 and 4 hours. have nausea and
bactericidal. *Peritonitis risk of bilirubinemic vomiting.
Ceftriaxone is widely *Granulocytopenia
Inhibits distributed in most
encephalopathy. .
bacterial cell organs, tissues and *Biliary infection , *Anemia -Through the
fluids, including the WARNINGS
wall synthesis. Hemoglobin test,
gallbladder, liver, - Risk of *Hemolytic, see if you do not
*Gastrointestinal
kidneys, bones, uterus, pseudomembranous have anemia.
ovaries, sputum, bile,
*Thrombocytopeni
colitis, superinfection
and pleural and synovial *Wounds
by non-susceptible a - Constantly
fluids. The duration of
effective plasma
microorganism. monitor whether
*Renal *Pruritus
concentrations is you do not have
considerable: thus, for Hyperbilirubinemic *Multiform edema any type of
example, after an
*Urinary allergy after
(can displace bilirubin
intramuscular dose of and dermatitis administration of
from serum albumin).
50 mg/kg, *Respiratory the medication.
concentrations of 35 to
*Allergic .
20 µg/ml are obtained in *Pneumonia
the middle ear and are
maintained for up to 48
hours. *Ears
 PHARMACOLOGY SHEET

GENERIC Clindamycin TRADENAME Dalacin-C Ledercef GROUP TO WHICH IT Anti-infective

NAME BELONGS therapeutics
MECHANISM PHARMACOKINETI INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING CARE
OF ACTION CS AND WARNINGS
Absorption: In the -Severe respiratory -Diarrhea -Check if the
CONTRAINDICATIONS patient has
form of bacterial infection;
- diarrhea after
hydrochloride (salt) of skin and soft -Hypersensitivity to
or palmitate ester, administration of
tissue: cellulite, clindamycin or pseudomembranous the medication.
It inhibits 90% is absorbed lincomycin.
-infected wounds
colitis, -nausea
bacterial through the -Check if you
protein digestive tract. Food -peri apical -Do not use in case -vomiting have nausea and
synthesis at the does not decrease abscess, -gingivitis of meningitis . vomiting.
-abdominal pain
level of the 50S its absorption, it can
-peritonitis
ribosomal only delay it. WARNINGS -flatulence -Check if you
subunit and Clindamycin is -osteomyelitis have abdominal
prevents the metabolized in the -History of -unpleasant metallic pain after
-septic arthritis
formation of liver and the hypersensitivity to taste administration of
-septicemia drugs or illness.
peptide bonds . resulting products the medication.
-female gastrointestinal. -pruritus
have variable
activity. genitourinary - vaginitis
Clindamycin and its -Infants.
infection
IM: pain, induration,
metabolites are -endometritis
eliminated through -Hepatic, renal and sterile abscess
the bile route and to -post-surgical blood control
-pelvic cellulite
IV: thrombophlebitis.
a lesser extent
through the kidneys. -salpingitis
 PHARMACOLOGICAL SHEET

GENERIC NAME Ketoprofen TRADENAME GROUP TO

WHICH IT
BELONGS
MECHANISM OF PHARMACOKINETI INDICATIONS CONTRAINDICATIONS ADVERSE NURSING CARE
ACTION CS AND WARNINGS EFFECTS
Ketoprofen is -Rheumatoid CONTRAINDICATIONS -Check if there is
administered orally, any alteration in
and absorption from arthritis. -Hypersensitivity the digestive
the gastrointestinal -Osteoarthritis. reactions -Dyspepsia, system.
tract is rapid and -Bronchospasm
almost complete. -Ankylosing -Asthma -Nausea
It inhibits Administration with
-Check if you
cyclooxygenase, spondylitis exacerbations -Abdominal pain, experience
food or milk -Rhinitis
which catalyzes decreases the rate, nausea and
-Acute episode of -Urticaria -Vomiting.
the formation of but not the extent, of vomiting after
prostaglandin absorption. gout. -Active peptic ulcer administration of
precursors from Bioavailability is the medication.
approximately 90%,
-Painful WARNINGS
acid. arachidonic -History of ulcerative
. reaching maximum symptoms -Check if you
plasma
colitis
have abdominal
concentrations in 1 associated with -History of HTN
and/or insufficiency. pain after
hour. Analgesia
inflammation Cardiac administration of
occurs after 1-2 hours
the medication.
and is maintained for (dental pain, -Risk of
3-4 hours s. gastrointestinal
trauma, post- bleeding, ulcer or
dental surgical perforation is greater
when increasing
pain ) doses of NSAIDs are
used