Customised Exam Guidelines
Customised Exam Guidelines
LIFE SCIENCES:
CUSTOMISED
EXAMINATION
GUIDELINES
GRADE 12
2021
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PLEASE NOTE:
This customised examination guidelines are not a substitute for the National Guidelines.
Different action verbs were used to guide emphasis and measurable responses from learners
as they interact with learning content
The guidelines chronicle learning and can also facilitate learners’ self facilitated learning.
Educators can also use this tool to assess learners’ responses and to measure progress in
interacting with the content.
Topic
THEME: DNA: THE CODE OF LIFE Covered
?/Tested
?
TOPIC: DNA: LOCATION, STRUCTURE AND FUNCTIONS
ACTION ELABORATION
VERB OR
PHRASE
Draw a structure of a cell labelling the ribosome, cytoplasm and the
parts of the nucleus
Mention two types of nucleic acids: DNA and RNA
Specify
the location of DNA:
Present in the nucleus (nuclear DNA) – makes up genes on
chromosomes
Present in mitochondria (mitochondrial DNA)
Present in chloroplasts (plants)
Briefly the history of the discovery of the DNA molecule (Watson &
describe Crick, Franklin & Wilkins)
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Give functions of DNA:
DNA makes up genes which carry hereditary information
DNA contains coded information for protein synthesis
TOPIC:DNA REPLICATION
Describe the process of DNA replication:
When in the cell cycle it takes place
Where in the cell it takes place
How DNA replication takes place (names of enzymes not
required)
The significance of DNA replication
TOPIC:DNA profiling
Interpret DNA profiles
Draw a
labelled structure of RNA
Describe
the structure of RNA
A single-stranded molecule consisting of nucleotides
Three components of an RNA nucleotide:
Nitrogenous bases
o Four nitrogenous bases of RNA:
o adenine (A), uracil (U), cytosine (C), guanine (G)
Sugar portion (ribose in RNA)
Phosphate portion
Draw
diagram of mRNA and tRNA molecules to illustrate their structure
Mention function of RNA:
RNA plays a role in protein synthesis
TOPIC:PROTEIN SYNTHESIS
Describe The involvement of DNA and RNA in protein synthesis:
Transcription
o The double helix DNA unwinds.
o The double-stranded DNA unzips/weak hydrogen bonds
break to form two separate strands.
o One strand is used as a template
o to form mRNA
o using free RNA nucleotides from the nucleoplasm.
o The mRNA is complementary to the DNA.
o mRNA now has the coded message for protein synthesis.
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mRNA moves from the nucleus to the cytoplasm and
attaches to the ribosome.
Translation
o Each tRNA carries a specific amino acid.
o When the anticodon on the tRNA
o matches the codon on the mRNA
o then tRNA brings the required amino acid to the ribosome.
o (Names of specific codons, anticodons and their amino
acids are not to be memorised.)
o Amino acids become attached to each other by peptide
bonds
o to form the required protein.
Specify
Site of meiosis in plants and in animals
Describe
Events of interphase:
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DNA replication takes place
o Chromosomes which are single threads, become double
o Each chromosome will now consist of two chromatids
joined by a centromere
o DNA replication helps to double the genetic material so
that it can be shared by the new cells arising from cell
division
Describe
events of the following phases of Meiosis I, using diagrams:
Prophase I - including a description of crossing over
Metaphase I – including the random arrangement of
chromosomes
Anaphase I
Telophase I
Describe
events of each phase of Meiosis II, using diagrams:
Prophase II
Metaphase II – including the random arrangement of
chromosomes
Anaphase II
Telophase II
TOPIC: IMPORTANCE OF MEIOSIS
THEME:REPRODUCTION IN VERTEBRATES
TOPIC: DIVERSITY OF REPRODUCTIVE STRATEGIES
Describe the role of the following reproductive strategies in animals in
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maximising reproductive success in different environments (using
relevant examples):
External fertilisation and internal fertilisation
Ovipary, ovovivipary and vivipary
Amniotic egg
Precocial and altricial development
Parental care
THEME:HUMAN REPRODUCTION
INTRODUCTION
Describe and the schematic outline of the human life cycle to show the role
draw of meiosis, mitosis and fertilisation
TOPIC: STRUCTURE OF THE MALE REPRODUCTIVE SYSTEM
Draw, label the structure of the male reproductive system
and describe
Give functions of the testis, epididymis, vas deferens, seminal vesicle,
prostate gland, Cowper's gland, penis and the urethra
TOPIC: STRUCTURE OF THE FEMALE REPRODUCTIVE SYSTEM
Draw a structure of the female reproductive system
labelled
Give
Functions of the ovary, Fallopian tubes, uterus lined by
endometrium, cervix, vagina with its external opening and the
vulva
Draw, label the structure of the ovary showing the primary follicles, the
and describe Graafian follicle and the corpus luteum
TOPIC:PUBERTY
Describe the main changes that occur in male characteristics during puberty
under the influence of testosterone
Draw, label
the structure of a sperm
and describe
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Give
functions of the parts of a sperm cell (acrosome, head with
haploid nucleus, middle portion/neck with mitochondria and a tail)
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Give functions of the following parts:
Chorion and chorionic villi
Amnion, amniotic cavity and amniotic fluid
Umbilical cord (including umbilical artery and umbilical vein)
Placenta
differentiate
between Genes and alleles
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Mention
genetics problems involving each of the three types of dominance
Calculate
proportion and ratio of genotypes and phenotypes
TOPIC: SEX DETERMINATION
Describe how sex is determined as follows:
22 pairs of chromosomes in humans are autosomes
and one pair of chromosomes are sex
chromosomes/gonosomes
Males have XY chromosomes and females have XX
chromosomes
Differentiate
between sex chromosomes (gonosomes) and autosomes in the
karyotypes of human males and females
TOPIC: MUTATIONS
Definition mutation
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Describe
the effects of harmful mutations, harmless mutations and useful
mutations
Describe
how mutations contribute to genetic variation
Differentiate
between gene mutation and chromosomal mutation
Outline
How the two types of gene mutations haemophilia and colour
blindness can alter characteristics leading to genetic disorders
as follows:
Haemophilia – absence of blood-clotting factors
Colour-blindness – due to absence of the proteins that
comprise either the red or green cones/photoreceptors in the
eye
Describe
how chromosomal mutation, Down syndrome occurs as follows:
Down syndrome – due to an extra copy of chromosome 21 as a
result of non-disjunction during meiosis
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TOPIC: CENTRAL NERVOUS SYSTEM
Explain how the brain is protected as follows
the brain and spinal cord are protected by meninges
Specify
the location and give functions of the following parts:
Brain
o Cerebrum
o Cerebellum
o Corpus callosum
o Medulla oblongata
Spinal cord
PERIPHERAL NERVOUS SYSTEM
Specify Specify the location and functions of the peripheral nervous system
(cranial and spinal nerves)
TOPIC: AUTONOMIC NERVOUS SYSTEM
Specify The location of and functions of the autonomic nervous system
(sympathetic and parasympathetic sections)
TOPIC: STRUCTURE AND FUNCTIONING OF A NERVE
Describe The functions of nerves as follows:
Nerves send and carry signals to and from all parts of the body
and are made up of neurons (sensory or motor)
Give
Functions of sensory and motor neurons
Describe and
draw labelled structure and parts of sensory and motor neurons
focusing on : nucleus, cell body, cytoplasm, myelin sheath, axon
and dendrites
TOPIC:THE SIMPLE REFLEX ARC
Define a reflex action and a reflex arc
Draw
A labelled structure of a reflex arc and give functions of each part
focusing on : receptor, sensory neuron, dorsal root of spinal
nerve, spinal cord, interneuron, motor neuron, ventral root of
spinal nerve, effector
Describe
the functioning of a simple reflex action, using an example
Describe
the significance of a reflex action
Describe
The significance of synapses
TOPIC: DISORDERS OF THE CNS
Mention Causes and symptoms of the following disorders of the nervous
system:
Alzheimer's disease
Multiple sclerosis
TOPIC: RECEPTORS
Give functions of receptors, neurons and effectors in responding to the
environment
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Mention different stimuli which the body responds to .
(light, sound, touch, temperature, pressure, pain and chemicals
(taste and smell). (No structure and names necessary except for
names of the receptors in the eye and ear.)
TOPIC: HUMAN EYE
Draw A labelled structure of the parts of the human eye, and give functions of
each part
Define
Binocular vision and outline its importance
State
the changes that occur in the human eye for each of the following:
Accommodation
Pupillary mechanism
Draw
Diagrams to highlight changes in the human eye for each of the
following:
Accommodation
Pupillary mechanism
Describe
the nature and treatment of the following visual defects:
Short-sightedness
Long-sightedness
Astigmatism
Cataracts
Draw
Diagrams to highlight the following visual defects:
Short-sightedness
Long-sightedness
Astigmatism
Cataracts
TOPIC: HUMAN EAR
Structure of the human ear and the functions of the different parts,
using a diagram
Describe
functioning of the human ear in:
Hearing (include the role of the organ of Corti, without details of its
structure)
Balance (include the role of maculae and cristae, without details
of their structure)
Describe
cause and treatment of the following hearing defects:
Middle ear infection (the use of grommets)
Deafness (the use of hearing aids and cochlear implants)
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Vasodilation
Vasoconstriction
THEME: RESPONDING TO THE ENVIRONMENT
(PLANTS)
TOPIC: PLANT HORMONES
Give general functions of the following:
Auxins
Gibberellins
Abscisic acid
Describe
the control of weeds using plant hormones
Describe
the role of auxins in:
Geotropism
Phototropism
Explain
the contribution of each of the following to variation that
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exists amongst individuals of the same species:
Meiosis
o Crossing over
o Random arrangement of chromosomes
Mutations
Random fertilisation
Random mating
Differentiate
between the following types of variation:
Continuous variation – those characteristics where there is a
range of inter- mediate phenotypes, e.g. height
Discontinuous variation – those characteristics that fall into
distinct catego ries e.g., blood groups
TOPIC: ORIGIN OF AN IDEA ABOUT ORIGINS (A HISTORICAL
DEVELOPMENT)
Highlight ideas on evolution in the order of their origin as follows:
Lamarckism
Darwinism
Punctuated Equilibrium
TOPIC: LAMARCKISM (JEAN BAPTISTE DE LAMARCK – 1744–1829)
Mention two 'laws' used by Lamarck to explain evolution as follows:
'Law' of use and disuse
'Law' of the inheritance of acquired characteristics
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do not change or change gradually through natural
selection (known as equilibrium).
This alternates with (is punctuated by) short periods of
time where rapid changes occur through natural selection
during which new species may form in a short period of
time.
TOPIC: ARTIFICIAL SELECTION
Describe artificial selection involving the following:
A domesticated animal species
A crop species
FORMATION OF NEW SPECIES
Define biological species concept as:
similar organisms that are capable of interbreeding to produce
fertile offspring
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Plant adaptation to different pollinators
Infertile offspring
Prevention of fertilisation
EVOLUTION IN PRESENT TIMES
Describe Any ONE example of natural selection and evolution in present
times using the following:
Use of insecticides and consequent resistance to insecticides
in insects
Development of resistant strains of tuberculosis-causing
bacteria (MDR and XDR) to antibiotics, due to mutations
(variations) in bacteria and failure to complete antibiotic
courses
HIV resistance to antiretroviral medication
Bill (beak) and body size of Galapagos finches
EVIDENCE OF COMMON ANCESTORS FOR LIVING HOMINIDS, INCLUDING
HUMANS
Interpret a phylogenetic tree to show the place of the family Hominidae in
the animal kingdom
Mention
characteristics that humans share with African apes
Give
anatomical differences between African apes and humans, with
the aid of diagrams, as it applies to the following characteristics:
Bipedalism (foramen magnum, spine and pelvic girdle)
Brain size
Teeth (dentition)
Prognathism
Palate shape
Cranial ridges
Brow ridges
Mention and
lines of evidence that support the idea of common ancestors for
describe
living hominids including humans:
Fossil evidence: Evidence from fossils of different ages show
that the anatomical characteristics of organisms changed
gradually over time.
Emphasis on evolutionary trends provided by the
anatomical features of fossils of the following three genera:
o Ardipithecus
o Australopithecus
o Homo
as well as:
o The age of each fossil found/time-line for the existence
of the three genera
o The fossil sites where they were found: emphasis on the
fossil sites that form a part of the Cradle of Humankind
o The scientists who discovered them
Genetic evidence: mitochondrial DNA
Cultural evidence: tool-making
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OUT-OF-AFRICA HYPOTHESIS
Outline the Out-of-Africa hypothesis as follows:
Modern humans originated in Africa and then migrated to
other continents
Interpret
timeline for the existence of different species of the genus
Homo and significant features of each of fossil type to show the
differences amongst them
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