CEFTRIAXONE (ROCEPHIN ®)
0.5 gm----1 gm
USUAL DILUENTS
D5W, NS
Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]
[0 to 1 gram] [50 ml] [30 min]
[ Over 1 gram] [100 ml] [30 min]
STABILITY / MISCELLANEOUS
Label: Refrigerate. Total daily dose should not exceed 4 grams.
STABILITY DATA:
Stability Stability Reconstituted P-Insert
Drug Refrigerated Room Temp. Vial/Powder Notes Updated
Sterile powder should
be stored at 20° to 25°C
(68° to 77°F) and
protected from light. The color of
After reconstitution, solutions ranges from
protection from normal light yellow to amber,
light is not necessary. depending on the
2 days Room Temp. length of storage,
Ceftriaxone 10 days (25°C) concentration and 06 06
Powder Refrigerated (4°C) Powder diluent used. 14
Store in a freezer
capable of
maintaining a
temperature of -
20°C/-4°F.
The thawed
solution is stable Check for minute
for 21 days under The thawed solution is leaks by squeezing
refrigeration stable for 48 hours at container firmly. If
(5°C/41°F). Do not room temperature leaks are detected,
refreeze thawed (25°C/77°F). Do not discard solution as
Ceftriaxone antibiotics. refreeze thawed sterility may be 08 15
Solution antibiotics. Solution impaired. 14
IM injection preparation:
250 mg/ 0.9 ml;
500mg/ 1.8 ml;
1 gram/3.6 ml;
2grams/ 4.2 or 7.2 ml
(H20; BS-H20; 0.5 to 1% lidocaine)
Usual dose: 1-2g ivpb q24h. Severe: 2g ivpb q12h.
No dosage adjustments required in renal failure.
PD: 750mg ivpb q12h
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INDICATIONS AND USAGE
Before instituting treatment with ceftriaxone, appropriate specimens should be obtained for isolation of the causative
organism and for determination of its susceptibility to the drug. Therapy may be instituted prior to obtaining results of
