DD Guidelines Block II 1st Year
DD Guidelines Block II 1st Year
| Guidelines
Guidelines
Table of Specifications
5
Recommended Books
5
Module 3: Musculoskeletal & Locomotion-I
6
Contents
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 2 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
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DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 3 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
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DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 4 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
Table of Specifications
MBBS Block-II
Written Exam Oral/Practical/Clinical Exam
Theme Subject MCQS SEQ OSPE OSCE OSVE
(1 mark (5 mark Marks (8 marks (8 marks (16 marks Marks
EACH) EACH) EACH) EACH) EACH)
Normal Anatomy
35 04 55 05 - 01 56
Structure Applied/Clinical
Physiology
17 02 27 01 - 01 24
Normal Applied/Clinical
Function Biochemistry
11 01 16 01 - 01 24
Applied/Clinical
Community
Medicine & 06 - 06 - - - -
Disease Burden Public Health
& Prevention
Behavioral
04 - 04 - - - -
Sciences
Pathophysiology Pathology 07 - 07 - - - -
&
Pharmaco-
therapeutics Pharmacology 05 - 05 - - - -
CFRC CF-1-2 - - - - 01 - 08
PERLs PERLs-1-2 - - - - 01 - 08
Recommended Books
ANATOMY
• Langman’s Medical Embryology by T.W. Sadler (LANGMAN) – 14th Ed.
• The Developing Human, Clinically Oriented Embryology by Keith L. Moore (KLM) – 10th Ed.
• Medical Histology by Laiq Hussain (LAIQ) – 6th Ed.
• Moore Clinically Oriented Anatomy (KLM) by Keith L. Moore – 8th Ed.
PHYSIOLOGY
• Guyton and Hall Textbook of Medical Physiology by John E. Hall (G&H) – 13th Ed.
• Essentials of Medical Physiology by K Sembulingam (JAYPEE) – 6th Ed.
BIOCHEMISTRY
• Lippincott’s Illustrated Reviews: Biochemistry by Richard A. Harvey (LIPPIN) – 8th Ed.
• Harper’s Illustrated Biochemistry by Robert M. (HARPER) – 30th Ed.
• Biochemistry by Dr. U. Satyanarayana (SATYA) – 5th Ed.
• Textbook of Medical Biochemistry by Dr (Brig) MN Chatterjea (CJ) – 11th Ed.
PATHOLOGY
• Robbins Basic Pathology Vinay Kumar, Abul K. Abbas, Jon C. Aster (MEDIUM ROBBINS) – 10th Ed.
• Review of Medical Microbiology and Immunology by Warren Levinson (LEVINSON) – 16th Ed.
PHARMACOLOGY
• Katzung & Trevor's Pharmacology: Examination & Board Review by Bertram G. Katzung (MINI KATZUNG) – 13th Ed.
COMMUNITY MEDICINE
• Excel Community Medicine and Public Health by Dr. Muhammad Naveed Alam (EXCEL) – 13th Ed.
• Park's Textbook of Preventive and Social Medicine by K. Park (PARK) – 23rd Ed.
BEHAVIORAL SCIENCES
• Handbook of Behavioral Sciences by Mowadat H Rana (MR) – 3rd Ed.
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 5 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
UPPER LIMB
MS-A-001 to MS-A-005
MS-A-001 PECTORAL REGION
MS-A-002 DERMATOMES AND CUTANEOUS INNERVATION OF UPPER LIMB
MS-A-003 PECTORAL REGION & BACK + MAMMARY GLANDS
MS-A-004 BONES OF UPPER LIMB: CLAVICLE & SCAPULA
MS-A-005 BONES OF THORAX, JOINTS OF UPPER LIMB: STERNOCLAVICULAR JOINT
• Definition of Dermatomes + Dermatomes diagram
• Superficial Veins + Lymph Nodes Along with their Drainage
• Medial cubital vein significance
• Platysma – Nerve supply + Action
• Breast (especially CA breast and Lymphatic drainage)
• Origin, Insertion, Innervation & Actions of Appendicular Muscles
• Clavipectoral Fascia
• Superficial, Intermediate & Deep Layers of Intrinsic Back Muscles
• Triangle of Auscultation and Lumbar Triangle of Petit
• Shrugging Muscle with Nerve Supply [TRAPEZIUS]
• Latissimus Dorsi
• Muscle Involved in Overhead Abduction
• Muscle forming Posterior Axillary Fold
• Scapulohumeral (Intrinsic Shoulder) Muscles
• Rotator cuff / Musculotendinous Cuff of Shoulder (SITS)
• Subacromial Bursa
• Quadrangular space with Contents
• Axillary Nerve
• Anastomoses Around Scapula Diagram
• Movements of Scapula
• Clinicals
- Clinical testing of Pectoralis Major
- Poland Syndrome
- Witch’s Milk
- Peu de orange appearance
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 6 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-A-006 AXILLA
• Boundaries & Contents
• Axillary Artery
• Axillary Lymph Nodes
• Brachial Plexus + Brachial plexus diagram
• Clinicals
- Brachial Plexus Injuries
- Erb's Paralysis
- Waiter's Tip Position
- Backpackers palsy
- Klumpke’s Paralysis
- Regimental badge area
MS-A-006 Develop clear concepts of the topographical anatomy of Axilla and its contents SNELL Ch 3 Pg 106-107
MS-A-006 Describe the boundaries of Axilla. (Identification of muscles forming the boundaries of SNELL Ch 3 Pg 106-107
axilla)
MS-A-006 List the contents of Axilla SNELL Ch 3 Pg 106-107
MS-A-006 Perform dissection/ Identify the Axilla and its contents SNELL Ch 3 Pg 106-107
MS-A-006 Describe Axillary Artery with reference to its 3 parts their relations, branches, and SNELL Ch 3 Pg 153-155
anastomoses
MS-A-006 Describe the formation, tributaries, and drainage of Axillary Vein SNELL Ch 3 Pg 159
MS-A-006 Identify and demonstrate the course/ relation and branches/tributaries of axillary SNELL Ch 3 Pg 153,159
vessels
MS-A-006 Describe the Axillary Lymph Nodes in terms of location, grouping, areas of drainage and SNELL Ch 3 Pg 159-162
clinical significance
MS-A-006 Describe the course, relations, root value and distribution of Axillary nerve. SNELL Ch 3 Pg 147
MS-A-006 Describe the boundaries and contents of quadrangular space. SNELL Ch 3 Pg 106
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 7 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-A-013 to MS-A-024
MS-A-013 BONES OF FOREARM
MS-A-014 MUSCLE OF ANTERIOR/FLEXOR COMPARTMENT OF FOREARM
MS-A-015 MUSCLE OF LATERAL AND POSTERIOR/EXTENSOR COMPARTMENT OF FOREARM
MS-A-016 NERVES OF FOREARM
MS-A-017 BLOOD SUPLY OF FOREARM
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 8 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-A-025 to MS-A-028
MS-A-025 HAND & ACTIONS OF MUSCLES OF UPPER LIMB AS A FUNCTIONAL UNIT
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 9 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
LOWER LIMB
MS-A-030 to MS-A-037
MS-A-030 HIP BONE
MS-A-031 FEMUR
MS-A-032 FASCIA LATA
MS-A-033 NEUROVASCULAR SUPPLY OF THIGH
MS-A-034 FEMORAL TRIANGLE & CANAL
MS-A-035 MUSCLES OF ANTERIOR COMPARTMENT OF THIGH
MS-A-036 NEUROVASCULAR SUPPLY OF ANTERIOR COMPARTMENT OF THIGH
MS-A-037 ADDUCTOR CANAL
• Hip bone
• Femur
• Cutaneous Nerves
• Lumbosacral Plexus
• Superficial Inguinal Lymph Nodes & its Groups Along with Drainage
• Subcutaneous Bursae
• Deep Fascia & its Modifications
• Iliotibial Tract
• Saphenous Opening
• Femoral Triangle
• Femoral Sheath
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 10 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
• Anatomical Location of Femoral Canal, Femoral Ring, its Boundaries & Contents
• Femoral Artery
• Profunda Femoris Artery
• Femoral Vein & its Tributaries
• Femoral Nerve
• Muscles of Anterior Thigh → Flexors of Hip Joint
• Muscles of Anterior Thigh → Extensors of Knee Joint
• Adductor / Hunter’s / Subsartorial Canal
• Clinicals
- Bone marrow biopsy in Hip bone
- Weaver’s Bottom
- Coxa Vara & Coxa Valga
- Femoral Fractures
- avascular necrosis of the femoral head
- Psoas Abscess
- Meralgia Paresthetica & Injury to Femoral Nerve + Consequences
- Housemaid’s / Miner’s Knee
- Runner’s Knee (Chondromalacia Patellae)
- Patellar Tendon Reflex / Knee Jerk (& its Root Value)
- Riders’ Bones
- Femoral Artery Pulse & its Abnormalities + Cannulation
- Saphenous Varix
- Femoral Hernias
- Abnormal Obturator Artery and its Surgical Significance
- Site of Intramuscular Injection in Thigh
MS-A-030 Draw and label the Parts of the hip bone, with its attachments. SNELL Ch 11 Pg 514-516
MS-A-030 Describe the parts, attachments of hip bone SNELL Ch 11 Pg 514-516
MS-A-030 Identify the parts and bony features of the hip bone, with its attachments, important SNELL Ch 11 Pg 514-516
relations
MS-A-030 Demonstrate the side determination of hip bone, its bony features, attachments SNELL Ch 11 Pg 514-516
MS-A-031 Describe the parts, attachments, side determination of femur SNELL Ch 11 Pg 516-518
MS-A-031 Identify the parts and bony features of the femur, with its attachments. SNELL Ch 11 Pg 516-518
MS-A-031 Demonstrate the side determination of femur, its bony features, attachments, and SNELL Ch 11 Pg 516-518
important relations (correlate these with fractures)
MS-A-031 Describe coxa Vara and coxa valga and their clinical significance SNELL Ch 11 Pg 516-518
MS-A-032 Describe the extent, attachments, and modifications of Fascia Lata SNELL Ch 11 Pg 525, 532
MS-A-032 Demonstrate the attachment of fascia Lata, iliotibial tract SNELL Ch 11 Pg 525, 532
MS-A-033 Describe the cutaneous nerves and vessels of thigh SNELL Ch 11 Pg 525
MS-A-033 Draw and label the cutaneous nerve supply of thigh SNELL Ch 11 Pg 525
MS-A-033 Describe the formation, course, relations, tributaries, and termination of the SNELL Ch 11 Pg 533-536
superficial veins
MS-A-033 Explain the anatomical justification of venesection, varicose veins, and saphenous SNELL Ch 11 Pg 533-536
venous grafts
MS-A-033 Describe the lymphatic drainage of the region with special emphasis on afferent and SNELL Ch 11 Pg 537
efferent of inguinal lymph nodes
MS-A-033 Identify the superficial and deep lymph nodes SNELL Ch 11 Pg 537
MS-A-033 Explain the anatomical justification for enlargement of inguinal lymph nodes SNELL Ch 11 Pg 537
MS-A-034 Describe and identify the Boundaries and contents of femoral triangle SNELL Ch 11 Pg 541
MS-A-034 Draw and label the Boundaries and contents of femoral triangle SNELL Ch 11 Pg 541
MS-A-034 Identify the femoral sheath with its compartments SNELL Ch 11 Pg 542
MS-A-034 Describe the formation of femoral sheath and its significanc SNELL Ch 11 Pg 542
MS-A-034 Describe the formation of femoral canal and its contents and significance SNELL Ch 11 Pg 542
MS-A-034 Describe the formation and significance of femoral ring SNELL Ch 11 Pg 542
MS-A-034 Compare and contrast the anatomical features of femoral and inguinal hernias SNELL Ch 11 Pg 543
MS-A-035 Tabulate the muscles of anterior compartment of thigh with their attachments, nerve SNELL Ch 11 Pg 540
supply and actions
MS-A-035 Demonstrate and identify the muscles of anterior compartment of thigh with their SNELL Ch 11 Pg 540
proximal and distal attachments
MS-A-035 Demonstrate the actions of muscles of anterior compartment of thigh SNELL Ch 11 Pg 540
MS-A-035 Explain the anatomical basis of psoas abscess SNELL Ch 11 Pg 540
MS-A-036 Identify and demonstrate the nerves and vessels of anterior compartment of thigh SNELL Ch 11 Pg 543-545
along with their branches
MS-A-036 Describe the origin, course, relations, branches, distribution, and termination of SNELL Ch 11 Pg 543-545
femoral artery
MS-A-036 Describe the origin, course, relations, tributaries, area of drainage and termination of SNELL Ch 11 Pg 543-545
femoral vein
MS-A-036 Describe the origin, course, relations, branches, distribution, and termination of SNELL Ch 11 Pg 543-545
femoral nerve
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 11 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-A-036 Tabulate the muscles of anterior compartment of thigh with their attachments, nerve SNELL Ch 11 Pg 543-545
supply and actions.
MS-A-037 Describe the formation, boundaries, contents of adductor canal SNELL Ch 11 Pg 541
MS-A-037 Identify and demonstrate the boundaries and contents of adductor canal SNELL Ch 11 Pg 541
MS-A-038 to MS-A-039
MS-A-038 MUSCLES OF MEDIAL COMPARTMENT OF THIGH
MS-A-039 NEUROVASCULAR SUPPLY OF MEDIAL COMPARTMENT OF THIGH
• Boundaries & Contents of Medial Thigh Region
• Actions of Muscles of Medial Thigh → Adductors of Hip Joint
• Obturator Nerve
• Comparison of Femoral & Obturator nerves
• Accessory Obturator Nerve → Pectineus
• Obturator Artery & Medial Circumflex Femoral Artery
• Clinicals
- Surgical Division of Obturator Nerve
- Nerve Entrapment Syndrome [Caused by Retroperitoneal Tumors]
- Transplantation of Gracilis
- Referred pain in joints
MS-A-038 Describe Muscles of medial compartment of thigh with their proximal and distal SNELL Ch 11 Pg 546
attachments, innervation and actions
MS-A-038 Identify the muscles of medial compartment of thigh with their proximal and distal SNELL Ch 11 Pg 546
attachments
MS-A-038 Demonstrate the actions of the muscles of the compartment on self/ subject SNELL Ch 11 Pg 546
MS-A-039 Describe the origin, course, relations, branches/ tributaries, distribution, and SNELL Ch 11 Pg 546-547
termination of neurovascular structures of medial compartment of thigh
MS-A-039 Identify the nerves and vessels of medial compartment of thigh along with their SNELL Ch 11 Pg 546-547
branches
MS-A-039 Describe and identify the lumbar and sacral plexus and its branches supplying the SNELL Ch 7,8 Pg 395,
lower limb 396, 397, 430-432
MS-A-039 Describe the cutaneous nerve supply and lymphatics of the region SNELL Ch 11 Pg -
MS-A-041 to MS-A-044
MS-A-041 MUSCLES OF POSTERIOR COMPARTMENT OF THIGH
MS-A-042 BLOOD SUPPLY OF POSTERIOR COMPARTMENT THIGH
MS-A-043 SCIATIC NERVE
MS-A-044 HIP JOINT
• Cutaneous Innervation
• Muscles of Posterior Thigh Region (Hamstrings)
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 12 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
• Sciatic Nerve
• Arterial Supply of Posterior Thigh Region
• Anastomosis on Back of Thigh
• Clinicals
- Sciatica
- Semimembranosus Bursitis / Baker’s Cyst
- Hamstring Injuries
MS-A-041 Describe the Attachments of muscles of posterior compartment of thigh with the SNELL Ch 11 Pg 549
innervation and action
MS-A-041 Identify the muscles of posterior compartment of thigh with their proximal and distal SNELL Ch 11 Pg 549
attachments
MS-A-041 Demonstrate the actions of muscles of posterior compartment of thigh SNELL Ch 11 Pg 549
MS-A-041 Describe the anatomical basis of signs and symptoms of sciatica. SNELL Ch 11 Pg 549
MS-A-042 Describe the origin, course, relations, branches, distribution, and termination of SNELL Ch 11 Pg 549
Profunda femoris artery
MS-A-042 Describe blood supply on back of thigh SNELL Ch 11 Pg 549
MS-A-042 Describe the origin, course, relations, branches, distribution, and termination of sciatic SNELL Ch 11 Pg 549
nerve
MS-A-043 Describe the origin, course, relations, branches, distribution, and termination of sciatic SNELL Ch 11 Pg 529
nerve
MS-A-043 Describe the anatomical basis, signs and symptoms of compression of or injury to SNELL Ch 11 Pg 529
sciatic nerve
MS-A-044 Describe the hip joint with its type, articulations, ligaments, stabilizing factors SNELL Ch 11 Pg 574-577
MS-A-044 Movements, and neuro-vascular supply with clinical significance. SNELL Ch 11 Pg 574-577
MS-A-044 Perform the movements of hip joint at various angles and be able to describe the SNELL Ch 11 Pg 574-577
muscles producing the movement. Discuss important associated clinical conditions
(Hip dislocation, Arthritis, Hip joint stability and Trendelenburg sign) movements, and
neurovascular supply with clinical significance.
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 13 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-A-047 to MS-A-051
MS-A-047 MUSCLES OF LEG
MS-A-048 NEUROVASCULAR SUPPLY OF LEG
MS-A-049 FLEXOR, EXTENSOR, AND PERONEAL RETICULA
MS-A-050 TIBIO-FIBULAR JOINT
MS-A-051 ANKLE JOINT
• Features & Contents of Superficial Fascia
• Deep Fascia of Leg( Intermuscular septa + Superior & Inferior Extensor Retinaculum)
• Muscles of Anterior Compartment of Leg
• Anterior Tibial Artery
• Deep Peroneal (Fibular) Nerve
• Dorsalis Pedis Artery
• Lateral / Peroneal Compartment of Leg
• Attachments of Peroneal Retinacula
• Muscles of Lateral Compartment of Leg
• Superficial Peroneal (Fibular) Nerve
• Tendons on Medial Side of the leg → Guy Ropes
• Superficial Fascia & Its Contents
• Short & Long / Great Saphenous Veins
• Deep Fascia
• Superficial Muscles of Posterior Compartment of Leg
• Deep Muscles of Posterior Compartment of Leg
• Posterior Tibial Artery
• Distribution of Peroneal (Fibular) Artery
• Tibial Nerve
• Clinicals
- Anterior Tibial Compartment Syndrome / Fresher’s Syndrome
- Compartmental Infections in leg & Fasciotomy
- Shin Splints / Tibialis Anterior Strain
- Injury to Common Fibular Nerve
- Superficial & Deep Fibular Nerve Entrapment / Injury & Consequences
- Location and Importance of Dorsalis Pedis Artery Pulse
- Anserine Bursitis
- Tarsal Tunnel Syndrome
- Injury to Tibial Nerve & Consequences
- Name of Sesamoid Bone in Gastrocnemius → Fabella
- Gastrocnemius Strain [Tennis Leg]
- Calcaneal Tendonitis, Bursitis & Calcaneal Tendon Reflex / Ankle Jerk [Root value]
- Location and Importance of Posterior Tibial Artery Pulse
MS-A-047 Describe the Muscles of anterior, lateral, and posterior compartments of leg with their SNELL Ch 11 Pg 557-562
proximal & distal attachments, innervation, and actions
MS-A-047 Identify the muscles of anterior, lateral, and posterior compartments of leg with their SNELL Ch 11 Pg 557-562
proximal and distal attachments
MS-A-048 Describe the origin, course, relations, branches/tributaries and termination of nerves SNELL Ch 11 Pg 557-562
and vessels of anterior, lateral, and posterior compartments of leg
Compartment Syndrome, Foot Drop
MS-A-048 Describe the cutaneous nerves and veins of leg SNELL Ch 11 Pg 554-556
MS-A-048 Draw and label the cutaneous nerve supply and dermatomes of leg SNELL Ch 11 Pg 554-556
MS-A-049 Identify the extensor, flexor, and peroneal retinacula and demonstrate the structures SNELL Ch 11 Pg 562-563
related to them
MS-A-049 Describe the attachments, relations, and structures passing under cover of, extensor, SNELL Ch 11 Pg 562-563
peroneal, and flexor retinacula
MS-A-049 Identify and demonstrate the nerves and vessels of anterior, lateral, and posterior SNELL Ch 11 Pg 562-563
compartments of leg along with their branches
MS-A-049 Describe the formation of noncalcareous (Achilles tendon) SNELL Ch 11 Pg 560
MS-A-050 Describe the articulations, muscles and nerve supply and movements at Tibiofibular SNELL Ch 11 Pg 583
joints
MS-A-051 Describe the ankle joint with its type, articulations, ligaments, movements, and nerve SNELL Ch 11 Pg 584-585
supply
MS-A-051 Describe the factors stabilizing the ankle joint. SNELL Ch 11 Pg 584-585
Discuss important associated clinical conditions.
MS-A-051 Identify and demonstrate the articulating surfaces and ligaments of ankle joint SNELL Ch 11 Pg 584-585
MS-A-052 to MS-A-057
MS-A-052 PLANTAR FASCIA
MS-A-053 MUSCLES OF FOOT
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 14 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-A-058 to MS-A-064
MS-A-058 ARTERIAL AND VENOUS DRAINAGE OF LOWER LIMB
MS-A-059 HUMAN GAIT
MS-A-060 LYMPHATIC DRAINAGE OF LOWER LIMB
MS-A-061 CUTANEOUS DERMATOMES & NERVE SUPPLY OF LOWER LIMB
MS-A-062 TOPOGRAPHICAL AND RADIOLOGICAL ANATOMY OF LOWER LIMB
MS-A-063 BONE FRACTURE
MS-A-064 JOINT DISLOCATION
• Venous Drainage of Lower Limbs
• Classification of the Veins in Lower Limbs
• Great & Short Saphenous Veins
• Perforating Veins and Their Classification
• Lymphatic Drainage of lower Limbs
• Classification of Lymph Nodes in Lower Limbs Along with Their Drainage
• Dermatomes & Myotomes in Lower limbs
• Clinicals
- Soleus as a Peripheral Heart
- Venesection / Cut-Open Procedure / Saphenous Cut-Down
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 15 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
EMBRYOLOGY
• Only use LANGMAN’s Medical Embryology by T.W. Sadler (LM).
• Additionally, prepare all Clinical from The Developing Human, Clinically Oriented Embryology by Keith L. Moore (KLM).
• Molecular genetics is part of syllabus but is LEAST IMPORTANT
• Must prepare Past UHS SEQS & MCQS from Past Paper Book "EPISODE FIRST YEAR"!
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 16 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
- Polydactyly
- Brachydactyly
- Syndactyly
- Congenital Club Foot
- Drug causing Amelia? [Answer → Thalidomide]
- Osteogenesis imperfecta
- Marfan syndrome
MS-A-066 Describe the process of limb development and limb growth LM Ch 12 Pg 168-170
MS-A-067 Name the molecular and genetic factors involved in the development of LM Ch 12 Pg 171
musculoskeletal system
MS-A-067 Describe the development of skeletal muscle and innervation of axial skeletal Muscles- LM Ch 12 Pg 171
developmental basis of myotome
MS-A-068 Describe the embryological basis of congenital anomalies related to muscular system. LM Ch 12 Pg 174-178
MS-A-068 Describe the clinical presentations and embryological basis of; i. Amelia ii. Meromelia LM Ch 12 Pg 174-178
iii. Phocomelia iv. Cleft Hand and Foot v. Polydactyly, Brachydactyly, Syndactyly
vi. Congenital club foot
HISTOLOGY
• Only use Medical Histology by Laiq Hussain (LAIQ).
• Most low yield portion
• Must prepare Past UHS SEQS & MCQS from Past Paper Book "EPISODE FIRST YEAR"!
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 17 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
PHYSIOLOGY
• Guyton and Hall Textbook of Medical Physiology by John E. Hall (G&H) is the Golden standard
• Prepare topics according to their importance as mentioned below.
• Must prepare Past UHS SEQS & MCQs from Past Paper Book "EPISODE FIRST YEAR"!
MS-P-001 to MS-P-009 Guyton and Hall Textbook of Medical Physiology by John E. Hall Chapter 5
MS-P-001 DIFFUSION / EQUILIBRIUM POTENTIALS
MS-P-002 NERNST POTENTIAL
MS-P-003 GOLDMAN EQUATION
MS-P-004 RESTING MEMBRANE POTENTIAL IN NEURONS
MS-P-005 NEURONS
MS-P-006 CLASSIFICATION OF NEURONS & FIBERS
MS-P-007 ACTION POTENTIAL OF NEURONS
MS-P-008 ROLE OF OTHER IONS IN ACTION POTENTIAL
MS-P-009 LOCAL / GRADED POTENTIALS
• Nernst Potential
• Goldmann Equation & Diffusion Potential
• Resting Membrane Potential of Neurons
• Effect of Hypokalemia & Hyperkalemia on RMP
• Stages of Action potential with Diagram
• Activation and Inactivation of Sodium and Potassium channels
• Role of Ca2+ in Action potential and TETANY
• Saltatory conduction
• Refractory Period & its Types
• Membrane Stabilizers
• Local Anesthetics
• “All or None” Principle
MS-P-001 Explain the Physiological basis of membrane potential GUYTON Ch 05 Pg 63
MS-P-001 Explain diffusion potentials of Na & K GUYTON Ch 05 Pg 63
MS-P-002 Define Nernst potential GUYTON Ch 05 Pg 63
MS-P-002 Explain Physiological Basis of Nernst potential GUYTON Ch 05 Pg 63
MS-P-002 Write the Nernst equation GUYTON Ch 05 Pg 63
MS-P-002 Calculate Nernst potential for Na & K GUYTON Ch 05 Pg 63
MS-P-002 Explain the effects of altering the concentration of Na+, K+, Ca on the equilibrium GUYTON Ch 05 Pg 63
potential for that ion
MS-P-003 Describe the normal distribution of Na+, K+, Ca and Cl- across the cell membrane GUYTON Ch 05 Pg 64
MS-P-003 Explain physiological basis of Goldman equation GUYTON Ch 05 Pg 64
MS-P-003 Clarify the role of Goldman equation in generation of Resting Membrane Potential GUYTON Ch 05 Pg 64
(RMP).
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
PAGE 18 OF 25
FIRST YEAR MBBS
GUIDELINES | BLOCK-II
MS-P-010 SYNAPSE Guyton and Hall Textbook of Medical Physiology by John E. Hall Chapter 45
• Classification of Synapse
• Signal Transmission across Chemical Synapse
MS-P-010 Classify and explain Physiological basis of different types of synapses EPISODE FIRST YEAR
MS-P-010 Elaborate how signal transmission takes place across chemical synapse EPISODE FIRST YEAR
MS-P-011 to MS-P-012 Guyton and Hall Textbook of Medical Physiology by John E. Hall Chapter 46
MS-P-011 CONDUCTION OF NERVE IMPULSE
MS-P-012 NERVE DEGENERATION
• Classification of Nerve Fibers on basis of Diameter & Conduction of Impulse
• Neuronal Circuit with both Excitatory and Inhibitory Output Signals
MS-P-011 Explain the mechanism of conduction of Nerve impulse in myelinated and unmyelinated GUYTON Ch 05 Pg 74
nerve fibers.
MS-P-011 Elaborate significance of saltatory conduction GUYTON Ch 05 Pg 74
MS-P-012 Explain Physiological basis& properties of Graded potential EPISODE FIRST YEAR
MS-P-012 Draw & explain Physiological basis & properties of compound action potential. EPISODE FIRST YEAR
MS-P-012 Contrast between action potential and graded potential EPISODE FIRST YEAR
MS-P-012 Describe the ionic basis of excitatory Post Synaptic Potential (EPSP), Inhibitory Post EPISODE FIRST YEAR
Synaptic Potential (IPSP), End Plate Potential (EPP).
MS-P-013 to MS-P-015 Guyton and Hall Textbook of Medical Physiology by John E. Hall Chapter 6
MS-P-013 SKELETAL MUSCLE
MS-P-014 CHARACTERISTICS OF WHOLE MUSCLE CONTRACTION
MS-P-015 MECHANICS OF MUSCLE CONTRACTION
• General Anatomy of skeletal muscles
• Define Sarcomere & Changes in Sarcomere during Muscle Contraction
• General Mechanism of Contraction
• Molecular Mechanism [Sliding Filament Model, Walk Along Theory]
• Actin and Myosin
• Tension developed by Muscle
• Effect of muscle Length and Velocity on Force of Contraction
• Energetics of Muscle Contraction
• Isometric VS Isotonic contraction
• Fast VS Slow Muscle Fibers
• Mechanism of Skeletal Muscle Contraction
• Multiple Fiber Summation
• Frequency Summation
• Tetanization
• StairCase Effect / Treppe
• Remodeling of muscle
• Atrophy
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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• Hypertrophy
• Hyperplasia
• Muscle Denervation
• Rigor Mortis & Muscle Dystrophy
MS-P-013 Discuss the physiological anatomy of skeletal muscles. GUYTON Ch 06 Pg 79-81
MS-P-013 Differentiate b/w skeletal, smooth, and cardiac muscle GUYTON Ch 06 Pg 79-81
MS-P-013 Describe the structure of Sarcomere GUYTON Ch 06 Pg 79-81
MS-P-014 Differentiate between isometric and isotonic contraction by giving examples. GUYTON Ch 06 Pg 87-88
MS-P-014 Compare the fast and slow muscle fibers. GUYTON Ch 06 Pg 87-88
MS-P-015 Explain the mechanism of summation and Tetanization GUYTON Ch 06 Pg 88-91
MS-P-015 Describe staircase effect/Treppe phenomena GUYTON Ch 06 Pg 88-91
MS-P-015 Discuss the mechanism of skeletal muscle fatigue GUYTON Ch 06 Pg 88-91
MS-P-015 Explain the remodeling of skeletal muscle to match the function. GUYTON Ch 06 Pg 88-91
Describe the development of macro motor units in poliomyelitis.
MS-P-015 Explain the physiological basis of rigor mortis GUYTON Ch 06 Pg 88-91
MS-P-016 NEUROMUSCULAR JUNCTION Guyton and Hall Textbook of Medical Physiology by John E.
Hall Chapter 7
• Physiologic Anatomy of Neuromuscular Junction [NMJ]
• End-Plate potential [EPP]
• Formation and Destruction of Acetylcholine [Ach]
• Drugs that enhance or block neuromuscular junction
• Myasthenia Gravis
• Excitation-Contraction Coupling Mechanism
• Release of calcium from Sarcoplasmic Reticulum
• Draw & Label Neuromuscular Junction
MS-P-016 Describe the physiological anatomy of Neuro Muscular Junction (NMJ) GUYTON Ch 07 Pg 93-99
MS-P-016 Mechanism of Neuromuscular transmission & generation of End Plate Potential GUYTON Ch 07 Pg 93-99
MS-P-016 Explain features, pathophysiology & treatment of Myasthenia Gravis GUYTON Ch 07 Pg 93-99
MS-P-016 Describe the enhancers or blockers of neuromuscular transmission at the GUYTON Ch 07 Pg 93-99
neuromuscular junction.
MS-P-016 Discuss the steps/ events of excitation contraction coupling in skeletal muscle. GUYTON Ch 07 Pg 93-99
MS-P-017 SMOOTH MUSCLE Guyton and Hall Textbook of Medical Physiology by John E. Hall Chapter 8
• Types of Smooth Muscles
• Difference between Skeletal and Smooth muscles
• Latch Mechanism
• Contraction and Relaxation of Smooth Muscle
• Sources of Calcium in Skeletal and Smooth muscles
• Nervous and Hormonal control
• Types of Action Potential in Smooth Muscle Fiber
MS-P-017 Differentiate between types of smooth muscles GUYTON Ch 08 Pg 101-108
MS-P-017 Describe mechanism of smooth muscle contraction in comparison to skeletal muscle. GUYTON Ch 08 Pg 101-108
MS-P-017 Explain the physiological anatomy of neuromuscular junction of smooth muscle GUYTON Ch 08 Pg 101-108
MS-P-017 Explain the excitatory and inhibitory transmitters secreted at Neuro Muscular Junction GUYTON Ch 08 Pg 101-108
(NMJ) of smooth muscles.
MS-P-017 Explain the depolarization of multiunit smooth muscles without action potentials. GUYTON Ch 08 Pg 101-108
Explain the local tissue factors and hormones that can cause smooth muscle
contraction without action potential.
MS-P-017 Explain the regulation of smooth muscle contraction by calcium ions GUYTON Ch 08 Pg 101-108
MS-P-017 Explain membrane potential and action potentials in smooth muscles. GUYTON Ch 08 Pg 101-108
MS-P-017 Explain the phenomena of stress relaxation and reverse stress relaxation in smooth GUYTON Ch 08 Pg 101-108
muscles.
MS-P-017 Explain the LATCH mechanism GUYTON Ch 08 Pg 101-108
MS-P-017 Describe the significance of LATCH mechanism. GUYTON Ch 08 Pg 101-108
MS-P-017 Explain the nervous and hormonal control of Smooth Muscle Contraction. GUYTON Ch 08 Pg 101-108
BIOCHEMISTRY
• The syllabus of the Biochemistry portion for 1st year is very scattered.
• You have to prepare it primarily from these two books;
- Lippincott’s Illustrated Reviews: Biochemistry by Richard A. Harvey (LIPPIN)
- Harper’s Illustrated Biochemistry by Robert M. (HARPER)
• You may need to refer following books for certain topics;
- Biochemistry by Dr. U. Satyanarayana (SATYA)
- Textbook of Medical Biochemistry by Dr (Brig) MN Chatterjea (CJ)
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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MS-B-001 to MS-B-003
MS-B-001 CLASSIFICATION CARBOHYDRATES
MS-B-002 CARBOHYDRATES
MS-B-003 EXTRACELLULAR MATRIX
• Introduction (Glycobiology, Glycome & Glycomics)
• Hemiacetal
• Aldoses & Ketoses Sugars
• Pentoses of Physiological Importance
• Hexoses of Physiological Importance
• Lactose vs Lactulose
• Disaccharides of Physiological Importance
• Hydrolysis Products & Structures of Physiologically Important Disaccharides
• Glycemic Index
• Structure, Source & Biomedical Importance of Cellulose & Glycogen
• Proteoglycan vs Glycoprotein
• Which GAG used as Anticoagulant & What is its Structure
• Which GAG used in Treatment of Osteoarthritis & its structural properties
• Glycosaminoglycans & their Structures
• Relationship between glycosaminoglycan Structure and Function
• Lactose Intolerance Scenario
• Collagen synthesis and metabolism
• Vitamin C (Complete)
• Osteogenesis Imperfecta
MS-B-001 Classify carbohydrates along with structure and biomedical importance of each class EPISODE FIRST YEAR
MS-B-002 Explain the isomerization of carbohydrates LIPPIN Ch 07 Pg 83-84
MS-B-003 Describe the physical and chemical properties of carbohydrates EPISODE FIRST YEAR
MS-B-003 Differentiate between proteoglycan and glycoproteins EPISODE FIRST YEAR
MS-B-003 Describe the components of the extracellular matrix: EPISODE FIRST YEAR
1. Describe structure, functions and clinical significance of glycosaminoglycans LIPPIN Ch 04 Pg 44-50
2. Discuss structure and functions of Fibrous proteins (collagen and Elastin)
3. Interpret diseases associated with them on basis of sign/symptoms and data LIPPIN Ch 28 Pg 381
4. Interpret the importance of vitamin C in collagen synthesis
5. Describe sources, active form, functions and deficiency diseases of vitamin C
6. Identify defects in collagen synthesis based on given data (Ostegenesis Imperfecta) LIPPIN Ch 04 Pg 49
MS-B-003 Interpret genetic basis of Duchene muscular dystrophy -
MS-B-003 Explain the transport and uptake of glucose in cells, steps of glycolysis and citric acid LIPPIN Ch 08, 09 Pg 97-114
cycle along with enzymes, co enzymes and cofactors involved
MS-B-005 to MS-B-011
MS-B-005 PROTEIN DIGESTION & TRANSPORT ACROSS CELL
MS-B-006 REACTIONS INVOLVE IN CATABOLISM
MS-B-007 TRANSPORTATION OF AMMONIA TO THE LIVER
MS-B-008 & MS-B-009 UREA CYCLE
MS-B-010 PROTEIN METABOLISM
MS-B-011 INBORN ERRORS OF AMINO ACID METABOLISM
• Classification of Amino Acids
• Standard amino acids & Non-standard (non-protein L-α-amino acids )
• Sulphur containing Amino acids & Aromatic Amino acids
• Selenocysteine & its significance
• Properties of Amino Acids and their Biomedical Importance
• Classification of Proteins based on Functions
• Urea Cycle
• Effect of Ammonia and Urea
• Catabolic pathways of Amino Acids
• All Clinical correlates of Amino Acid Metabolism
MS-B-005 Describe the digestion and absorption of proteins in mouth, stomach and small LIPPIN Ch 19 Pg 147-150
intestine. Discuss the uptake of amino acids by cells
MS-B-006 Explain following reactions with enzymes involved in it: 1. Transamination LIPPIN Ch 19, 21 Pg 250-
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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GUIDELINES | BLOCK-II
AGING
MS-Ag-001 BONE
MS-Ag-002 CARTILAGE
MS-Ag-003 MUSCLE
MS-Ag-004 EFFECT OF ESTROGEN ON BMD
MS-Ag-01 Discuss the effect of age on bone fragility and its implications with management EPISODE FIRST YEAR
MS-Ag-02 Discuss the effect of age on loss of cartilage resilience and its implications and EPISODE FIRST YEAR
management
MS-Ag-03 Discuss the effect of age on Muscular strength and its implications and EPISODE FIRST YEAR
management
MS-Ag-04 Explain the protective effect of estrogen (female sex hormone) on bone mineral EPISODE FIRST YEAR
density and relate it to increased prevalence of postmenopausal fractures in
women.
PHARMACOLOGY
MS-Ph-001 DRUGS ACTING ON NEUROMUSCULAR JUNCTION (NMJ)
MS-Ph-002 DRUGS IN MYASTHENIA GRAVIS
MS-Ph-003 LOCAL ANESTHETICS
MS-Ph-01 Explain the mechanism by which drugs can stimulate NMJ. EPISODE FIRST YEAR
MS-Ph-01 Explain the mechanism by which drugs can block NMJ. EPISODE FIRST YEAR
MS-Ph-02 Discuss briefly the therapeutic effect of drugs used in myasthenia gravis EPISODE FIRST YEAR
MS-Ph-03 Discuss briefly the therapeutic effect of drugs used as local anesthetics. EPISODE FIRST YEAR
PATHOLOGY
MS-Pa-001 MUSCLE REMODELING
MS-Pa-002 DISEASES OF MUSCLE
MS-Pa-003 DISEASES OF BONE
MS-Pa-004 DISEASE OF CARTILAGE
MS-Pa-01 Describe the hyperplasia, hypertrophy, and atrophy of muscle fiber EPISODE FIRST YEAR
MS-Pa-01 Explain the histopathological basis of leiomyoma EPISODE FIRST YEAR
MS-Pa-02 Describe the histological basis of Duchenne Muscular Dystrophy and myopathy EPISODE FIRST YEAR
MS-Pa-03 Describe the clinical presentation and histological justification for osteoporosis, EPISODE FIRST YEAR
osteopetrosis
MS-Pa-03 Describe the histological basis for bone repair after Bone fractures EPISODE FIRST YEAR
MS-Pa-04 Describe the histological basis for cartilage growth and repair EPISODE FIRST YEAR
BEHAVIORAL SCIENCES
MS-BhS-001 PSYCHOSOCIAL FACTORS INFLUENCING CHRONIC ILLNESSES
MS-BhS-002 PSYCHOSOCIAL IMPACT OF DISEASE AND ITS MANAGEMENT
MS-BhS-001 Identify and deal with the various psychosocial aspects of Musculoskeletal EPISODE FIRST YEAR
conditions (such as Osteoarthritis, Osteomyelitis, Rheumatoid arthritis, Gout,
chronic back pain, psychosomatic complaints) and Neuromuscular conditions
(Muscular dystrophy, Myasthenia Gravis, Sclerosis) on Individual, Family and
Society
MS-BhS-002 Identify the psychosocial risk factors as mediating factors between illness and EPISODE FIRST YEAR
its effect.
MS-BhS-002 Discuss the role of psychological variables like coping, social support, and other EPISODE FIRST YEAR
health cognitions in mediating between illness and its effect.
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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COMMUNITY MEDICINE
MS-CM-001 BACK PAIN
MS-CM-002 WORK RELATED MUSCULOSKELETAL DISORDERS
MS-CM-003 MSD RELATED TO MOBILE USAGE
MS-CM-004 ERGONOMICS
MS-CM-005 NONCOMMUNICABLE DISEASE
MS-CM-006 RISK FACTOR ASSESSMENT OF MUSCULOSKELETAL DISEASES
MS-CM-001 Explain causes of low back pain EPISODE FIRST YEAR
MS-CM-001 Describe prevention of low back pain EPISODE FIRST YEAR
MS-CM-002 Describe work related musculoskeletal disorders addition with its EPISODE FIRST YEAR
burden/epidemiology
MS-CM-002 Identify risk factors of Musculoskeletal disorders MSD at workplace EPISODE FIRST YEAR
MS-CM-002 Describe prevention of exposure to risk factors related to workplace EPISODE FIRST YEAR
MS-CM-003 Describe MSD related to mobile addition with its burden/epidemiology EPISODE FIRST YEAR
MS-CM-003 Describe MSD related to mobile usage (Text neck, Trigger thumb, DeQuervain EPISODE FIRST YEAR
Syndrome, Carpel Tunnel Syndrome) Identify risk factors related to MSD due to
excessive mobile usage
MS-CM-003 Describe the preventive strategies for mobile addiction-related MSD. EPISODE FIRST YEAR
MS-CM-004 Describe the application of ergonomics in MSD related to the above disorders. EPISODE FIRST YEAR
MS-CM-005 Describe the concept of non-communicable Musculoskeletal diseases EPISODE FIRST YEAR
MS-CM-006 Identify the risk factors in the community for Osteoporosis EPISODE FIRST YEAR
MS-CM-006 Learn and apply interventions to prevent the risk factors for various EPISODE FIRST YEAR
musculoskeletal diseases in the community.
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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GUIDELINES | BLOCK-II
EPISODESERIES
RECAPSERIES
DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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DR. ANAS FAROOQ, DR. MUHAMMAD SEERAT ALI & DR. ALI RAZA CHAUDARY
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