Ijo 69 3584
Ijo 69 3584
Purpose: To study the anatomical and functional outcomes of trans‑conjunctival 23G or 25G                                   Video Available on:
cannula‑guided modified posterior passive drainage of post‑operative suprachoroidal hemorrhage (SCH).                           www.ijo.in
Methods: A retrospective study was done on 15 eyes in the last nine years. Vitrectomy with perfluorocarbon
liquid injection to push SCH from inside along with 23G or 25G cannula‑guided passive drainage of                        Access this article online
SCH was performed by making multiple sutureless posterior sclerotomies at 10–15 mm behind the                            Website:
                                                                                                                         www.ijo.in
limbus. Postoperatively, best corrected visual acuity (BCVA), intraocular pressure (IOP), and posterior
                                                                                                                         DOI:
segment findings were compared from pre‑operative findings. Results: Mean age at presentation was                        10.4103/ijo.IJO_3533_20
64.93 ± 7.62 years. Complete resolution of SCH with attached retina was achieved in 60% (9/15) of                        PMID:
cases. Mean pre‑operative BCVA of Log MAR 2.82 ± 0.21 improved to mean post‑operative BCVA Log                           *****
MAR 1.04 ± 0.53 (P < 0.001). Mean pre‑operative IOP of 27.87 ± 8.67 mmHg improved significantly to                        Quick Response Code:
post‑operative IOP of 10.2 ± 5.16 mmHg (P < 0.001). Silicone oil removal was possible in 11/15 (73.33%) cases.
Conclusion: Posterior passive drainage of post‑operative SCH by multiple sclerotomies using 23G or 25G
cannulas can salvage these eyes with both anatomical and functional recovery.
Suprachoroidal Hemorrhage (SCH) is a rare vision‑threatening           into the suprachoroidal space to facilitate further outflow.[11‑14]
condition defined as a rapid accumulation of blood in the              Rossi T et al.[14] described SCH drainage through 23 Gauge (G)
suprachoroidal space.[1] The potential, virtual space between          cannula placed 3.5 mm from limbus using anterior chamber
sclera and choroid, the suprachoroidal space, contains                 maintainer. The use of 20G trocar/cannula system introduced
approximately 10 µL of fluid.[2] The literature revealed the           7 mm posterior to limbus has been advocated by Rezende FA
etiology of SCH to be spontaneous onset, trauma, or as a               et al.[13] However, recently, Rizzo et al.[15] described two‑stage
complication of ocular surgery.[3‑5] The incidence of SCH              management in nine cases of massive SCH. Few experimental
after ocular surgery varies, ranging between 0.04% and 1%,             treatment studies in animals and case reports in humans
for different procedures.[3,5,6] Delayed SCH is defined as a           showed the potential of recombinant tissue plasminogen
suprachoroidal hemorrhage that develops in the post‑operative          activator (r‑tPA) in SCH.[16‑18]
period but is not typically associated with the expulsion of
intraocular contents.[1] Factors that predispose to SCH include        Methods
advanced age, glaucoma, high myopia, systemic cardiovascular           The purpose was to study the anatomical and functional
disease, aphakia, and history of vitreous loss.[7‑9] Small loculated   outcomes of transconjunctival 23G or 25G cannula‑guided
collections of blood within the suprachoroidal spaces may              modified posterior passive drainage of post‑operative SCH as
resolve spontaneously with conservative treatment. Surgical            single‑stage management.
drainage is advised for uncontrolled raised intraocular pressure
with maximum possible medications, flat anterior chamber,                 The present study is an institutional, retrospective,
Retinal Detachment (RD), appositional or kissing SCH, retinal          interventional case series including 15 eyes of 15 consecutive
or vitreous incarceration, and prolonged SCH.                          patients. The study was conducted from May 2011 to
                                                                       September 2019 at a tertiary eye care hospital. A sutureless
   The use of perfluorocarbon liquid (PFCL) in vitreous                technique using a 23G or 25G trocar/cannula system (Alcon,
surgery was popularized by Dr. Stanley Chang.[10] In the past,         Fort Worth, TX) was used for drainage of post‑operative SCH.
surgical external drainage required radial 2–3 mm sclerotomies
combined with vitrectomy and use of PFCL and silicone oil
with the occasional introduction of a cyclodialysis spatula            This is an open access journal, and articles are distributed under the terms of
                                                                       the Creative Commons Attribution‑NonCommercial‑ShareAlike 4.0 License,
                                                                       which allows others to remix, tweak, and build upon the work non‑commercially,
                                                                       as long as appropriate credit is given and the new creations are licensed under
Department of Vitreoretina, Disha Eye Hospitals Pvt Ltd, Kolkata,
                                                                       the identical terms.
West Bengal, India
Correspondence to: Dr. Subhendu Kumar Boral, Disha Eye Hospitals       For reprints contact: WKHLRPMedknow_reprints@wolterskluwer.com
Pvt Ltd, 88 (63A) Ghosh Para Road, Barrackpore, Kolkata ‑ 700 120,
West Bengal, India. E‑mail: drsubhendu@yahoo.co.uk                      Cite this article as: Boral SK, Agarwal D. Modified posterior drainage
Received: 25-Nov-2020         Revision: 11-May-2021                     of post‑operative suprachoroidal hemorrhage. Indian J Ophthalmol
                                                                        2021;69:3584-90.
Accepted: 11-May-2021         Published: 26-Nov-2021
                                                               incarceration            detachment
XI           68   F   RE      10     2.9   Vitrectomy     24   Shallow AC       PCIOL    SCH (2 quadrants) +            25G         2      Retina on +  Done           0.6        12
                                           for RD                                        partially detached retina                         Resolved SCH
XII          59   F   LE      18     2.9   Phaco          30   PCIOL            PCIOL    Vitreous hemorrhage        25G             4      Retina on +  Not done       1.3        6
                                                                                         + SCH with kissing                                Residual SCH
                                                                                         choroidals + Total RD
XIII    56        F   RE 22        2.3     Vitrectomy 6        PCIOL            PCIOL    Total RD with Late SCH (2 25G        2            Retina on +  Done         0.78    11
                                           for RD (Late                                  quadrants)                                        Resolved SCH
                                           expulsive)
                                                                                                                                                                                        3585
                                                                                                                                                                             Contd...
3586                                                                                                    Indian Journal of Ophthalmology                                                                                                                                                                          Volume 69 Issue 12
                           Post op Postop
                                                                                                                                                                                                                                                                    participation. Patients consented to the publication of their
                                    (mm
                                     IOP
                                     Hg)
                                                                         15
                                                                                       12
                                                                                                                                                                                                                                                                    clinical findings and images. Institutional Ethical Committee
                                                                                                                                                                                                                                                                    approval was obtained. Present study strictly adhered to the
BCVA
                            MAR)
                            (Log
                                                                                                                                                                                                                                                                    tenets of the declaration of Helsinki. A complete ophthalmic
0.6
                                                                                       1
                                                                                                                                                                                                                                                                    evaluation was done after detailed history taking. Best
                                                                                                                                                                                                                                                                    corrected visual acuity (BCVA) and intraocular pressure (IOP)
                                                                                                                                                                                                                                                                    were recorded. B‑scan ultrasonography (USG) was done to
                                               Post‑operative Silicone
                                                              removal
                                                                                                                                                                                                                                                                    determine the site of maximum elevation of SCH and to assess
Done
                                                                                      Done
                                                                                                                                                                                                                                                                    any associated co‑morbidity like vitreous hemorrhage, kissing
                                                              oil
Resolved SCH
                                                                         Resolved SCH
                                                                         Retina on +                                                                                                                                                                                severe vision loss due to post‑operative SCH. Drainage of SCH
                                                                         Retina on +
                                                                                                                                                                                                                                                                    was contemplated only when USG showed SCH liquefaction.
                                    drainage Fundus
                                                                                                        PC IOL=Posterior Chamber IOL, AC IOL=Anterior Chamber IOL, ECCE=Extra Capsular Cataract Extraction, SCH=Supra Choroidal Hemorrhage, RD=Retinal Detachment
                                                                                                                                                                                                                                                                        Surgical technique: Peribulbar block followed by aseptic
                                                                                                                                                                                                                                                                    dressing and draping was done in all cases. Here we
                                                                                                                                                                                                                                                                    used a modified approach of posterior passive drainage
                           sugary sclerotomies
25G
                                                                                       25G
                             of
Aphakia
17
                                                                         for RD
                                                                         ECCE
2.9
2.3
10
LE
66
XV
a b c
d e f
g                                                 h                                                 i
Figure 2: Steps of suprachoroidal hemorrhage (SCH) drainage - (a and b) Oblique posterior introduction of 23G and 25G trocar-cannula complex,
respectively, in the presence of anterior chamber maintainer and (c) with infusion cannula; (d) perfluorocarbon liquid (PFCL) injection; (e) External
blood drainage; (f) Visible cannula tip after drainage; (g) PFCL removal; (h) Silicone oil injection; (i) Cannula removal
3588                                            Indian Journal of Ophthalmology                                         Volume 69 Issue 12
the sclerotomies made to drain SCH‑needed sutures after               drainage of SCH using transconjunctival, oblique posterior
removal of cannulas. The mean time interval from the onset            sutureless sclerotomies by 23G or 25G trocar‑cannula complex.
and intervention was 15.6 ± 8.09 days. We have used Snellen’s         B‑scan USG helps in not only the diagnosis of SCH but also
vision chart in our clinic. All BCVA was converted to logarithm       in determining its extent and association with other morbid
of the minimum angle of resolution (log MAR) for statistical          conditions like RD. Moreover, USG helps in determining the
analysis. As poor BCVA could not be quantified in Snellen’s           site and timing of SCH drainage. Liquefaction of blood in the
chart, it was converted into LogMAR value according to Wei Y          suprachoroidal space can be seen echo graphically and it usually
et al.[19], wherein light perception was assigned as 2.9 LogMAR,      occurs between 7 and 14 days.[21] This had been suggested as
hand movement as 2.6 LogMAR, and counting finger as 2.3               the ideal time for a vitreoretinal intervention. In the present
LogMAR. Pre‑operative mean BCVA was 2.82 ± 0.21 log MAR.              study, drainage of SCH was done only after ultrasonography
Post‑operative mean BCVA at 6 months was 1.04 ± 0.53 log              showed liquefaction of suprachoroidal hemorrhage. The mean
MAR. This visual gain following SCH drainage was found to             time interval between primary surgery and intervention in our
be statistically significant (P < 0.001). Postoperatively retina      study was 15.71 ± 8.92 days, which was comparable to that
was attached in all 15 cases. Anatomical stabilization was            observed by Lakhanpal V et al.[21] (mean of 14 days). However,
achieved in 9/15 cases [Fig. 3]. In case VI, glue‑assisted scleral    in 4/15 patients (Case II, VII, IX, and XIII), our intervention was
fixation of IOL was performed along with silicone oil removal         delayed due to the late referral of the patient.
after 3 months of vitrectomy. This patient had achieved a
final BCVA of 20/40 (Log MAR equivalent 0.3) [Fig. 4]. In                Our approach is different from the previous approaches
6/15 patients, residual SCH of various amounts persisted              and has multiple merits. First, the present sutureless
postoperatively [Fig. 5]. Silicone oil removal was possible           technique is less traumatic than the radial sclerotomies.[11]
in 11/15 (73.33%) cases. In Case IV and Case IX, silicone oil         Second, our drainage site is far more posterior, as posteriorly
was removed despite persistent residual suprachoroidal                made sclerotomies maximizes drainage of SCH. Drainage
blood. Mean IOP preoperatively was 27.87 ± 8.67 mm Hg and             sclerotomies were made 10–15 mm posterior to the limbus in a
improved postoperatively to 10.2 ± 5.16 mm Hg. This reduction         quadrant of maximum elevation of SCH on USG. Rossi T et al.[14]
in IOP was found to be statistically significant (P < 0.001). In      described the use of 23G cannula placed 3.5 mm posterior to
4/15 cases, silicone oil was not removed due to post‑operative        limbus for drainage of SCH and Rezende FA et al.[13] drained
hypotony.                                                             at 7 mm from limbus using 20G cannula. However, drainage
                                                                      of SCH posterior to the equator may not be possible by these
Discussion                                                            anteriorly placed cannulas. Thus, our approach is suitable to
Occurrence of SCH does not necessarily mean poor long‑term            drain even posterior SCH. Third, we used multiple 23G/25G
visual outcome. [20] All of our primary cases are cataract
extraction (n = 11) and vitrectomy for RD repair (n = 4).
However, surprising we never faced SCH after Glaucoma
Filtration Surgery in our setting. The present study introduces
a surgical technique of cannula‑guided posterior passive
a c
a                                 c
                                                                                                          d
                                                                                                          e
b                                 d                                   Figure 4: Shows (a) Pre-operative corneal edema, hyphema, and
Figure 3: Shows (a) Pre-operative corneal edema, retained             aphakia in Case VI, (b) Pre-operative B-scan ultrasonography (USG)
lens matters, and aphakia in Case I, (b) Pre-operative B-scan         showed suprachoroidal hemorrhage (SCH) in two quadrants, (c)
ultrasonography (USG) of the same patient showed suprachoroidal       Stable intraocular lens (IOL) position after silicone oil removal (SOR)
hemorrhage (SCH) in two quadrants, (c) Post-operative USG after two   and glued IOL implantation, (d) USG after SOR showed completely
weeks showed completely resolved SCH under silicone oil, (d) Retina   resolved SCH and e) Retinal status without any residual suprachoroidal
status after silicone oil removal                                     elevation after SOR
December 2021                        Boral and Agarwal: Posterior drainage of suprachoroidal hemorrhage                                        3589
                                                                          Conclusion
b                           c                                             In summary, useful vision can be restored in post‑operative
Figure 5: Shows a) Pre-operative ultra wide-field fundus picture of       SCH if timely and adequate drainage is performed. Sutureless,
suprachoroidal hemorrhage (SCH) with total retinal detachment (RD) in     minimally invasive passive drainage of SCH by posteriorly
Case IX, b) Pre-operative B-scan ultrasonography (USG) of the same        placed multiple 23G or 25G cannulas as single‑stage
patient showed kissing SCH with total RD, c) Post-operative ultra wide-   management can salvage these eyes and achieve both
field fundus picture of residual SCH with completely attached retina      anatomical and functional recovery. Still, there are some
                                                                          limitations present in our study. This is a single‑center study,
cannulas to maximize the drainage. Desai UR et al.[22] described          and the described cannula‑guided drainage of suprachoroidal
the use of PFCL to facilitate drainage of SCH. The role of heavy          blood is a slow process than radial sclerotomies. Moreover,
transparent fluid PFCL in the vitreoretinal procedure as an               complete drainage of SCH may not be always possible due to
important intraoperative tool has already been well established           incomplete clot lysis, even when there is liquefaction of SCH
because of its cohesive adherence to the retina due to its surface        on ultrasonography.
tension. Moreover, its high specific gravity helps in complex             Declaration of patient consent
scenarios such as in expulsive hemorrhage to exert a constant
                                                                          The authors certify that they have obtained all appropriate
uniform tamponading force to push the suprachoroidal
                                                                          patient consent forms. In the form, the patient(s) has/have
collected blood from inside to facilitate its drainage externally.
                                                                          given his/her/their consent for his/her/their images and other
Similarly, we use PFCL to maximize the push on SCH from
                                                                          clinical information to be reported in the journal. The patients
the inside. Further, keeping IOP high (40–60 mmHg) for a
                                                                          understand that their names and initials will not be published
short time facilitates more complete passive external drainage
                                                                          and due efforts will be made to conceal their identity, but
of SCH. Fourth, our approach is a single‑stage management.
                                                                          anonymity cannot be guaranteed.
We avoided the two‑stage procedure as described by Rizzo S
et al.[15] because long‑term use of PFCL causes toxic changes             Financial support and sponsorship
of retinal pigment epithelial cells and ganglion cells.[23,24]            Self.
Study showing the nontoxic effect of PFCL is based on the
animal model.[25] Fifth, our approach was minimally invasive,             Conflicts of interest
thereby limiting further trauma and inflammation avoiding                 There are no conflicts of interest.
360‑degree conjunctival peritomy to expose extra‑ocular
muscles as described by Rizzo S et al.[15] Sixth, we also avoided         References
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Commentary: The challenges of                                               Ultrasonography also helps to determine the location and
                                                                            extent of the hemorrhage and to differentiate between serous
managing suprachoroidal hemorrhage                                          and hemorrhagic choroidal detachment.
                                                                               The goals of surgery are to drain adequate amount of blood
Suprachoroidal hemorrhage (SCH) is a rare but one of
the most feared complications of all intraocular surgeries.                 from suprachoroidal space to prevent or relieve appositional
SCH has been associated more commonly with glaucoma,                        choroidal detachment, to normalize IOP, and to relieve pressure
vitreoretinal, and penetrating keratoplasty procedures and                  on lens‑iris diaphragm to prevent its forward movement
less with modern techniques of cataract surgery. The risk                   and anterior chamber angle closure. There is no need for
factors include intraoperative hypotony, chronic glaucoma,                  complete drainage of SCH. Unless an underlying pathology
high myopia, aphakia, old age (arteriosclerosis), and systemic              demands it, (i.e., breakthrough vitreous hemorrhage or retinal
hypertension. Patients on anticoagulation therapy can present               incarceration) concurrent vitrectomy is not needed.
with spontaneous SCH. The spectrum ranges from localized,
                                                                               Different methods have been described for surgical
self‑limiting SCH to expulsion of intraocular contents.[1]
                                                                            drainage of SCH. Placement of infusion cannula, either in the
   Limited SCH usually resolves spontaneously over 6–8 weeks.               anterior chamber or through the pars plana, helps in better
Continuous monitoring of intraocular pressure (IOP) and                     intraoperative IOP control and satisfactory SCH drainage. The
appropriate management is critical in these eyes. 30% of eyes               extent of the choroidal detachment and the ability to visualize
with massive SCH, if left untreated, had a final vision of no               posterior segment details decides the location for the infusion
light perception.[2]                                                        cannula.
    Early recognition during surgery and proactive restriction                 SCH can be drained by direct scleral cut down after limited
of further hypotony by closing wounds and raising IOP limit                 conjunctival peritomy or using trocar cannula system.
progression of the hemorrhage.[3]
                                                                               One or more radial sclerotomies are made 8 to 9 mm
   The most important factors for the decision of surgical                  posterior to the limbus in a quadrant/s with highest
intervention are the presence of appositional choroidal                     choroidal elevation. The detached choroid helps prevent
detachments, uncontrolled IOP with or without angle closure.                an accidental full‑thickness penetration. Typically dark
   The optimal timing for the drainage of SCH is controversial.             red blood gushes out after full‑thickness scleral incision.
Though the window of 7 to 15 days is accepted by most                       Gentle pressure can be maintained on the sclera to achieve
surgeons, planning this after ultrasonographic confirmation                 maximum possible drainage. The sclerotomies can either
of liquefaction of SCH helps in more complete drainage.[4,5]                be sutured or left open.