23/1/2019- Version 1

1. All of the following are non-competitive acetyl cholinesterase

inhibitors, except:
1- Donepezil
2- Rivastigmine
3- Galantamine (reversible and competitive ache inhibitor)
4- Tacrine

2. Mepredine not suitable for long time because???

1-cardiotoxicity
2-neurotoxicity (elderly)
3-nephrotoxicity

3. -case about patient recently widowed, is suffering from severe

depression, is taking imipramine(TCA) block the reuptake of :
1- serotonin
2- norepinephrine
3- serotonin and norepinephrine
4- dopamine

4. same case about the widow

TCA metabolized by:
a-CYP 450
b-amine hydroxlase
c-alcohol dehydrogenase

5. Same case about the widow

TCA block all of the following receptors except:
1- Histaminic receptors
2- Alpha adrenergic receptors
3- Beta adrenergic receptors
4- Muscarinic receptors (cholinergic)
6. Same case about the widow:
TCA used in all of the following except:
1- Panic disorders
2- Schizophrenia
3- Migraine
4- Neuropathic pain
7. Metabolic effects of BB include all of the following except:
1- Decreased glucagon release
2- Decreased glycogenolysis
3- Hypertriglyceridemia
4- Hyperglycemia

8. Least effect for BB in :

1- Benign prostatic hyperplasia
2- Myocardial infarction
3- Arrhythmia
4- Angina pectoris

9. All of the following decrease the effects of BB except:

1- Phenytoin
2- Phenobarbital
3- rifampin
4- Fluoxetine (increase effect of BB)

10. Female patients suffering from absence seizures, which of the

following is not indicated:
1- Ethosuximide
2- Lamotrigine
3- Diazepam
4- Carbamazepine

11. we are using all to treat absence seizure except:

a- phenytoin
b- valproic acid
c- ethosuximide
d- lamotrigine

12. What is the drug of choice for status epilepticus :

1- Phenytoin
2- Carbamazepine
3- Lamotrigine
4- Valproate

13. All of the following anti-epileptic drugs are avoided in pregnancy

except:
1- Phenytoin
2- Valproate
3- Diazepam
4- clonazepam

14. Doctor wants to discontinue anti-epileptic drug for female

patient, which of the following guarantees low recurrence:
1- EEG
2- History of frequent seizures
3- Onset in childhood
4- MRI

15. Anti cholinergic used for motion sickness :

-scopalamine

16. Patients develop tolerance against all of the following effects of

morphine except:
1- Respiratory depression
2- Euphoria
3- Analgesia
4- Pinpoint pupil (miosis)

17. All used for Morphine dependence except :

a. Methadone
b. Codeine
c. Clonidine
d. Buprenorphine

18. Case about patient suffering from severe skeletal muscle rigidity
and is diagnosed with myasthenia gravis, which of the following is NOT
true:
1- Diagnosed by edrophonium
2- Glucocorticoids are not useful in this condition
3- Autoimmune disease caused by antibodies against ACH receptors at
motor endplate

19. All of the following are used for treatment of acute mania except:
1- Lorazepam 2- Chlorpromazine
3- Lithium 4- Valproate
20. Toxicity of morphine can be reversed by:
1- Naltraxone

21. Which drug is not used in parkinson’s disease:

1- Chlorthalidone,
2- Bromocriptine
3- Amantadine
4- Rasagiline

22. Which of the following is CI in Parkinson:

1- Haloperidol

23. Long case about Parkinson patient:

What is the effect of carbidopa on levodopa:
1- Decrease its metabolism in the CNS
2- Decrease its peripheral decarboxylation to dopamine

24. What are the symptoms of parkinson:

1- Tremors and agitation
2- Inability to initiate voluntary movements
3- Abnormal posture and gait
Ans: all

25. Which of the following vitamins decreases the effects of

levodopa when taken concomitantly :
1- Vit B6 puridoxine
2- Vit B12
3- Vit B1
4- Vit B5

26. The decrease in the effect of levodopa occurs within:

11- After 5 years
2- After 3 years
3- After 2 years
4- From the 3rd to the 5th year

27. Pilocarpine is used in all of the following except:

1- In narrow angle glaucoma
2- Alternatively with mydriatics to separate the iris
3- In closed angle glaucoma
4- Standard one for open glaucoma

28. phenytoin side effect ,all except

a) gingival hyperplasia
b) nystagmus
c) nephrotoxicity
29. Which of the following is ultra-short barbiturates:
Penobarbital (long action)
Thiopental

30. Regarding Fluxetine :

a. half life is 50 hrs
b. have a metabolite as active as the parentdrug
c. used in bulimia nervosa
d.undergo first pass effect
answer... ALL

31. Which of the following used to make mydriasis in

checking refractive errors?
Atropine
Tropicamide

32. case scenario about female patient have GOUT was weak &
dizzy & fatigue and another problems like she can’t raise her hand and
having some blood disorders like agrnaulocytosis and leucopenia and
type of anemia which anti gout are probably to cause this Side effects :
a- allopurinol
b- colchicine

33. the qs about pharyngitis, the patient was penicillin allergic but
the organism is penicillin sensitive
A. Penicillin
B. Cephalosporin C. Azithromycin D. Tetracycline

34. Which one of tetracyclines is suitable for renal failure pt ( it was

in a case ) :
a. Doxycycline
b. Minocycline
c. Tetracycline
35. which of the following is not fungus:-
a-mushroom
b-E.coli

36. Bacteria move by :-flagella

37. mitochondrial toxicity,, ANTIVIRAL used:

a-lamivudine
b-amatidine
c-zidovudine
38. antiviral used in Parkinson :- amantadine
39. antiviral used for influenza and , Parkinson: ( came twice )
a-amantidine
b-lamuvidine
c-zidovudine

40. 19-used for HIV&HIB :- Lamivudine

41. In AIDS the CD4 less than:-

a-200
b-400
c-500
d-600

42. CD4 bind to which antigen in the HIV positive Pt:-

a-T lymphocyte
b-B lymphocyte

43. case scenario about patient HIV and have low fever and lung
diffuse and ask which negative myco bacterium like to cause this
infection :
Mycobacterium avium complex

44. TB. medication ,INH,PYZ,RMP ,which is the SE. of INH ( came as a

case ) :
answer... peripheral neuropathy

45. Which is not true about immune reconstitution inflammatory

syndrom :
1) corticosteroids and anti - inflammatory drugs don’t shorten
inflammation action .
2) The action of antiviral start when virus load is high .
3) The pt start respond to treatment when CD4 is high

46. Pt in the ICU for 3 days which antacid is used :-

a-PPIs

47. drug used in IBD(Inflammatory bowel disease) remission:

- infliximab

48. charcoal act by which :-

a-adsorbant
b-absorbant

49. SIADH(Syndrome of inappropriate antidiuretic hormone) cause all

of the following except:-
a-hyponatremia
b-hypernatremia
c-water excess
d-Inadequate vasopressin production

50. MTC means

a- Maximum toxic conc.
b- Maximum safe conc.

51. MEC mean : minimum effective concentration

52. Cmax stands for:-

a-the maximum conc that drug reach at t time

Tmax stands for:-

53. time at which plasma concentration reach maximum
54. above MTC : toxicity
55. Under MEC : ineffective

56. In high therapeutic index ( in a case )

b-no side effects

57 . 10 ml ampoule of 3% drug how many ml required to give 150mg

dose?
a-3ml
b-5ml
c-7ml
d-9ml

58. 50% alcohol is to be diluted with purified water, how many parts of
purified water (0% alchohol) to prepare 20% preparation.?
a- 30parts water + 20 parts 50% alchohol

59 . Dose for patient is 75mg, how ml needed from 125mg/5ml solution :

a. 5 ml
b. 3 ml
c. 15 ml

60 . How many gram of 5% ointment will be prepared from 2mg:

answer.. (5%= 5gm ----100 ,,2gm---?
2*100/5 = 40 gm

61 . How many gram will be in 250 ml(total) of 5% solution :

answer.. 5% = 5gm ---100ml
??--------250ml
= 250 *5 /100 = 12.5 gm

62. If dose of drug is 0.2 ml, How many dose will be in 15ml :
answer.. 15ml /0.2 ml =75 doses

63 . Advantages of IV route over oral route:

1- safe and convenient, rapid onset, dose can be titrated, can be
used in ER
2- safe and convenient, can be used in ER
3- rapid onset, dose can be titrated, can be used in ER
4- rapid onset, can be used in ER

64. Foam in pharmacy found as spray is used as:

1- Burn dressing and topical but not for rectal administration
2- Topical and rectal but not for burns
3- Topical, rectal and for burn dressing
4- Topical only

65 -which is true about dry gum emulsion:-

a-ratio 4:2:1
b-water gum and oil are added together and triturated slowly
c-oil and gum are triturated and water added slowly.

66. emulsion inversion:

a-conversion of W/O emulsion to O/w emulsion and vice versa

67. Conductivity in emulsion, the dispersed phase for such emulsion is:

1- Aqueous
2- Non aqueous
3- Aqueous and non aqueous
68 . velocity in dispersed phase affected by:-
a-particle size
b-particle homogeneity
c-elecrtic charge
d-all

69 . Conductivity test – Dilution test – Dye test used for which dosage
form :
a. Susp.
b. Emulsion
c. Foam
d. Gel

70. Particle size affects:

1- Suspend ability
2- Penetrability
3- Dissolution rate
4- Dose to dose uniformity
5- Uniformity of tablet
6- All of the above

71. Xanax‫ ®آ‬alprazolam (CDA) must store in:

a. Steel cupboard well closed
b. Cupboard opened by 2 person

72. 70 yr old diabetic pt on oral hypoglycemica and suffering from

hypertension ; Which of the following antihypertensive drugs is not
recommended :
1- losartan
2- enalapril
3- Hydrochlorothiazide
4- Atenolol

73. patient with hypertension put on antihypertensive drug, after few

months developed heart failure manifested as reduction in heart rate
and contraction, which antihypertensive drug patient put on:
a. Lisinopril
b. verpamil
c. prozosin
d. Thiazide diuretic

74. timolol is contraindicated in all the following except

A.HTN
b. Congestive Heart failure
c- Bronchial asthma

75. Beta blocker use in all except: Bronchial asthma

76. prinzmetal angina:

a-sudden spasm
b-sudden spasm with atherosclerosis
c-sudden spasm with atherosclerosis and not responsive to CCBs and
nitroglycerin
d- sudden spasm ,with atherosclerosis, and respond to CCBs and
nitroglycerin

77. which of the following not used in prinzmetal angina??

atenolol
nifedipine
nitroglycerin
dilitazem

78. years old Male patient , he is a smoker and he is taking an

antiarrhythmic medications , which of the following drugs should be
avoided :
A. Digoxin
B. Verapamil
C. Amiodrone
D. lidocaine

79. - Patient with arrhythmia discharged from the hospital which

medication used to control his condition :- verapamil

80 . Common side effects of arrhythmic drug:

torsade de pointe

81. CASE About Arrhythmia ( statements ) :

a-most cause of recurrent arrhythmia due to reentry
b-Most Of them is Calcium and sodium blocker
c-SA node is the pace maker ( something like that )
d.anti-arrythmic safer than operation

82. Patient with arrhythmia given medication that decrease the velocity
and force of contractility which one of this drugs :
a. Verapamil
b. enalapril

83. Mechanism of action of digitalis all true except:

a - increase contractility
b- decrease vascular resistance
c- have modify effect on autonomic nervous system
d- maintain ventricular rate in atrial fibrillation

84 . Case Patient with glaucoma and blood pressure 220/110 and

hypertensive crisis and ask which to avoid :-
a-nicardipine
b-fenoldopam
c-Na nitroprusside
d-labetalol

85. patient diagnosed with Hyperlipidemia and decreased HDL , what is

the drug useful in his condition ?
A) Niacin
B) Clofibrate
C) Cholestyramine
D) Rousavastatin
86. CI of loop diuretic except:- renal impairment

87. Thiazide diuretic doesn’t cause

1. hypokalemia
2. hypokalemia
3. hypocalcemia
4. Hyponatremia

88. All are route of administration of nitroglycerin except :-oral

89. The role of B-blocker in MI is all of the following except:

a-Decrease mortality and morbidity
b- decrease infract size
c- Increase O2 demand
 90. The dry cough in ACE inhibitors: EXCEPT:
A. Accumulation of bradykinin
B. In women more than men
C. Appears in 6 months
D. Dose related

91 . which one must be labeled and separated : epinephrine

92 . case about a child had hypersentivity reaction to bee sting :

epinephrine

93 . anti glacucoma means : drug that decreses

IOP

94. graph : how much time it will stay in body:

24 h
95. how much conc at time 12 hr : 5ng/mL
96. how much t max : 3 h

97. Primaquine is contraindicated in all of the

following except:
1- SLE,RA
2- G6PD deficiency
3- Lactating female
4- Pregnancy

98 . Ipratropium approved for: Maintaining COPD

99. atropine least S.E : - decrease gastric secretion

100. easy calculation question , can’t recall the exact numbers .

‫ال تنسوني من دعائكم‬

GOODLUCK people !!!

Shatha Ayan

23/1/2019- Version 2

Hello doctor ,
This material is for HAAD exam (23 jan 2019),,if you are reading
this, you need to be sure that you already studied 1st notes dr.rawda
2nd classifications and 3rd the exams from 2019 to 2015. so have a
nice day and be optimistic the exam will be very easy and am sure
you can pass it, all the questions are repeated.

@1. Aspirin overdose symptoms are all of the following except:

a. Hypothermia (actually it cause fever)
b. Metabolic acidosis
c. Respiratory depression

@2- Patient with gout history present to ER with gouty attack, which NSAID is
contraindicated:
Aspirin
Prophylaxis in this case ???
Acute Attack: Indomethacin (NSAID),colchicine, CS

@3 - Nail with thick texture and brown discoloration, fungal infection of the
nail. DOC:
a. Fluconazole
b. Terbinafine Or Itraconazole (as 1st line)
c. Griseofulvin

@4 - Acyclovir is not effective in which viral infection”causative agent”? The

options are NOT diseases but viruses names!
a. Herpes zoster
b. Epstein-barr virus
C.CMV
d. herpes zoster

@5 - Type of penicillin that cannot be administered IV:

a. Penicillin G (IM, Continuous IV)
b. Penicillin V orally..the only one. (as tab+sol)

@6 - Female is menopause, she experiences hot flushes, developed spinal

osteoporosis which to use?
Alendronate 1st choice, 2nd choice: OCP-Combination (Estrogen
+Progesteron)
@7 -ACEI’s beneficial effect is caused by all of the following mechanisms
except:
Vasodilation by inhibition of bradykinin metabolism=bradykinin
accumulation=(not beneficial)
@8 - Patient taking ACEl (ramipril) which antacid should not be used:
a. Calcium carbonate
b. Magnesium
c. Aluminum
d. Potassium bicarbonate=risk of hyperkalemia

@9 - Sulfasalazine prevents the absorption of which element?

Folate

@10 - Sulfasalazine should be given with which supplement?

Folic acid

@11 - New born infant had an infection he was given medication and kept
under supervision; after 6 days he developed depressed breathing, gray
coloration and rash, which drug is most likely he's on?
Chloramphenicol= gray baby syndrome, depression of bone marrow.

*@12 - Female taking UTI medication, after few days she developed rashes
and red spots on hands, face, (they mean to say exposed areas) what
medication she's on? They attached a hand that shows red spots with the
question.
quinolones,ttc, acyclovir, amiodarone, diuretics)

*13- A Kid took peanut butter and he’s allergic to peanut; he developed
rashes and urticarial. What type of allergic reaction is this? Allergy to food
a. Type 1
b. Type 2
c. Type 3
d. Type 4

@14- Read about Acetaminophen (paracetamol) full mechanism of action,

and its effect in Reyes disease in kids with fever related to viral infection.
you can choose more than one true statement.
a. Acetaminophen has a great anti-inflammatory
b. inhibit PG in CNS
c. It has no risk in Reyes disease for kids with viral fever
d. irreversible cox3 inhibitor

@15- Not a side effect of (ACEIs) ramipril:

a. Hypokalemia
b. Low level of potassium
c. angioedema
d. hyperkalemia.
e. dry cough

@16- All of the following cause constipation except:

a. Bisacodyl = given for constipation
b. Morphine= constipation
c. Calcium
d. ACEI

@17- patient with TB take more than one drug why??

To decrease the risk of developing drug-resistance

@18- When giving ethambutol (for treatingTB) for a long duration,

continuous follow-up/check-up is necessary because of this condition:
a. Renal failure
b. Liver dysfunction
c. vision problem

@19- DOC in bacterial meningitis:

Cefuroxime. OR cefotaxime OR ceftriaxone

*@20- Patient was found to have an infection with gram +ve and -ve, which
drug to use? We have to choose a broad spectrum antibiotic
Amoxicillin

@21-What is the medication that’s used in the treatment of glaucoma,

medication-related edema, heart-failure related edema?
Acetazolamide
*@22- What is the antiviral that’s the most suitable for HSV infection? Get a
general idea about HSV viral infection please
HSV=Acyclovir 200mg 5 times for 7 days.
Herpes Varicella Zoster=Acyclovir 800mg 5 times

@23- Pharmacist monitoring of drug dispensing and refill will give an idea
about:
a. Drug utilization
b. Drug disposal
c. Drug adherence

*@24-What’s the type of study that’s MOST reliable?

a. Cohort randomized
b. Case study
c. Case report
d. Case scenario

*@25- What’s the type of study that’s LEAST reliable? Memorize types of
studies please
a. Cohort randomized
b. Case study
c. Case report
d. Case scenario

@26- Manufacturer recall of medication from pharmacy is called:

Voluntary call

@27- Approved duration for the use of tamoxifen (breast cancer in

men+women) is:
10 yrs

@28-patient with panic attack what is DOC

a. buspirone
b. benzodiazepine
c. antidepressant
d. barbiturate

@29- benzodiazepines do all actions, except:

a-anticonvulsant
b-muscle relaxant
c-Anterograde amnesia + (anxiolytic, hypnotic)
d-anti psychotic

@30- Patient has a problem in bowel emptying, he develops pain while

passing stool. Which is the least likely condition to cause this problem?
Hypothyroidism slows the action of gastric tract=constipation
Hyperthyroidism quick the action of gastric tract=diarrhea.

@31- Patient take DMARDs and after 2 weeks have eye problem, Which
DMARD related to vision problem:
hydroxychloroquine

*32- Patient present to ER because of gouty attack, he was given NSAID,

when should we consider giving prophylaxis therapy for gout: ((you can
choose more than one))
- more than One attack per year
- Association with Kidney stones
- Urate excretion more than 500 mg (Normal: 500-1000)
-Uric acid more than 10mg

*@33- Digoxin cannot be used in which condition:

a.Heart failure OR Complete heart failure
b.Along with ACEI and diuretics
c.In ventricular rate in atrial fibrillation
d.Left diastolic HF + Complete Heart Block
e. Right Systolic HF

*34- All of the following are indications of diabetes except:

a. Polyuria and unexplained weight loss
b. Random blood glucose of 200
c. Fasting blood glucose of 140
d. Blood glucose level of 200, 2 hours post oral glucose intake

@35-insulin secrets form which cell ?

B cell in pancreas

*@36-All can resist (ie distroy) Beta lactamase enzyme except (sensitive to
the enzyme):
a.Augmentin (amoxicillin +clavulanic acid)
b. doxycycline (tetracycline)
c.Dicloxacilln a member of penicillin’s (contain beta lactam
structure) family
d. azithromycin (macrolides)
Sensitive to Beta lactamase= Dicloxacillin
Resisting Beta lactamase= Augmentin, Doxycycline, Azithromycin.

*@37- Study acetyl salicylic acid(aspirin) full mechanism of action as an

analgesic-irreversible cox inhibitor and cardio protective “cox2”. how?
Acetyl salicylic acid (aspirin)characterized by :
1) cardio protective action
2) Prophylaxis in MI
3) Cause Reyes Disease in kids
4) antiplatelet action
5) Analgesic
6) antipyretic
7) anti-inflammatory action
8) Irreversible Cox inhibitor

All of the above.

*@38 – Azathioprine (DMRD= SE not dose related :

Infection

@39- which of the following no need for antibiotic dose adjustment ?

a.hypercholesterolemia
b.elderly patient
c.renal disease patient
d.AIDS

@40- Patient with TB has discoloration in urine (reddish color) on which

medication?
a.Rifampicin
b. Ethambutol
c. Isoniazid
d. Pyrama

*41- patient on cyclophosphamid has developed hematuria due to release of

which :
a. phosphoramide mustard
b. Acrolein
c. Mensa

*@42- Which is true about Digoxin MOA is:

Positive inotropic effect
@43 drug given for ductus arteriosus in neonates:
Indomethacin (NSAID)

*@44 - which of the following cause depression in T-lymphocyte:

abatacept

*@45 - Which of the following S.E of B2 agonist (bronchodilation) that most

people=more common may have?
a. Hypokalemia
b. Hypomagnesia
c. Tremor

*@46- Patient has irritable bowel disease, the doctor advice the patient to
remove dairy products from his diet, which symptoms patient have:
a- chronic Constipation
b- chronic diarrhea
Note: dairy products, Ca+ cause constipation

*@47- Etoposide cause DNA damage through inhibition:

a. Topoisomerase I
b. Topoisomerase II
c. Topoisomerase III
d. Topoisomerase IIII

@48- prostaglandin that can be used for glaucoma and eyelash

Hypotrichosis
a. Lantoprost
b. Travoprost
c.bimatoprost
d. tafluprost

@49 - Acyclovir MOA:

a. DNA polymerase inhibitor

*@50- Aortic dissection DOC along with B blocker (reduce heart rate +
cardiac contractility):
Sodium nitroprusside vasodilation (arteries+veins)
AD « 1st line BB alone or in combination with Na Nitroprusside
AD « 2nd line CCBs like verapamil / diltiazem
*@51- smoker with COPD , what is the drug of choice ?
a. Busonide
b. Ipratopium
c. Theophyllin
d. Montelukast

*52- A physician wants to switch a terminally-ill patient from slow release

morphine sulphate tablets, 15 mg twice daily, to a liquid morphine sulphate
dosage form because the patient has difficulty in swallowing tablets. If a
morphine sulphate solution containing 5 mg per mL is prescribed q4h, what
volume should be dispensed for a 20 day supply to provide the same pain
relief as the tablet regimen?
a.20 mL
b.60 mL
c.100 mL
d.120 Ml
‫المسألة الوحيدة في هذا األمتحان‬

@53-Action of insulin (reduce blood glucose level to normal) are all true
except (wrong answer):
Decrease glucose production in liver
Decrease liver glucose uptake x it increases glucose uptake by the liver
Insert glucose in muscle and adipose tissue

*@54- Which is contraindicated with sulfa sensitivity

Celecoxib

@55 - Penetration through CSF )cerebrospinal fluid( depends on all except:

a.Lipid soulibility
b.Water soulibility
c.Mwt
d.protein binding

@56 -female take antibiotics and suffer from ear problem which AB cause
this:
Amikacin

*@57 – all used in motion sickness except:

Cinnarazine
Hyoscine (scopinal)
Scopolamine “anti-muscarnic »
Promethazine HCL
propamide

@58- Study heparin mechanism of action.

injectable anticoagulant mechanism of heparin:
-inhibit platelet aggregation (aspirin, clopidogrel.. oral)
-anti-thrombin 3

59- Patient was diagnosed with malignant glioma and doctor decides to put
him on chemotherapy agents. Which of the following is DOC:
Temozolomide 1st lie
Or carmustine 2nd line

*@60- Cyclosporine toxicity/SE will increase if given in which route:

IV = exactly like Acyclovir when given IV

*@61- Study letrazole(breast cancer) M.O.A and SE, you can choose more
than one answer.
I choose aromatase inhibitor with no androgenic Side effects.

*@62- True about SSRI:

Safest one to use for long term.

@63- Used in emergency HTN:, not in MI patient

Na nitroprusside (Vasodilator-arteries+veins) cause
prompt/excessive hypotension=reflux tachycardia

*@64 - NSAID Associated with CNS side effects:

Mefenamic acid

*@65- Which of the following causes tachycardia:

a. B blocker
b. verapamil (CCB)
c. diltiazem (BZD)
d.isosorbide dinitrate (Vasodilator-arteries)+alpha 1 R blockers

*@66- patient with ED (erectile dysfunction) and take Sildenafil which CI with
sildenafil (vasoconstriction):
isosorbide dinitrate (vasodilation)

*@67- Not to be used in Chrons disease:

a. Adalimumab
b. Certolizumab
c. Etanercept
d. Another biological treatment

*@68 - Which not used in heart failure:

Captopril
Digoxin
Nefidipine*
Propranolol*

*@69 - Cromylin Na used in asthma as :

Decrease inflammation
Mast cell stabilizer

*@70- patient have hair loss (bladness) ‫ الصلع‬, the doctor give him topical
treatment is:
Minoxidil

*@71 - The DOC for acute attack of asthma:

Albuterol or salbutamol (b2 agonist)

*@72 - patient came to the pharmacy and have chest pain (angina), the
pharmacist decide to refer the patient to cardiologist because:

The pain radiating on neck and shoulders, arms and jaw

@73 - The best advice to a patient taking corticosteroid inhaler for asthma
(you can choice more than 1 choice)

a) Take rapid/slow breath after pressing the inhaler

 b) Hold your breath for 10 seconds after complete inhalation

c) rinse your mouth with water after using the inhaler=decrease

risk of oral thrush.

d) keep one finger distance between your lips & the inhaler

*@74 - Patient was on cyclosporine and changes to tacrolimus. Tacrolimus

comparison with Cyclosporine: (you can choice more than 1 answer)
a. more potent
b. Less nephrotoxicity+ neurotoxicity
c. longer duration
d. Lower rejection rate
e. all of the above

*@75 - which of the following drugs acts on T-lymphocyte blocking?

-adluximab
-etanercept
-alefacept

@76) Which of the following no need for antibiotic dose adjustment:

a.hypercholesterolemia

b. elderly patient

c. renal disease patient

d. AIDS

*@77.Enfuvirtide added to HIV patient regimen what true about it:

a. integrase inhibitor . (Wrong as its fusion inhibitor)

b. administered S.C

c. can be used without reconstitution = must reconstitute

d. low side effects

answer: B & D
*@78 . all are DMARDs except:

MTX
Answer: Prednisolone

*@79) which statement is true about letrozole:

a. mild androgenic SE, aromatase inhibitor.

b. aromatase inhibitor, not cause endometriosis, mild androgenic SE.
c. aromatase inhibitor, no need corticosteroid co- administration, mild
androgenic SE.
d. aromatase inhibitor, no need corticosteroid co-administration, not cause
endometriosis, no androgenic SE.
Answer: D

*@80) Contraceptive contraindicated with lactating mother?

a. Progestin alone (progesterone alone is safe)

c. combination* (progesterone + *estrogen=not safe in lactating mother,

inhibit breast milk) = 2nd choice, 1st choice: estrogen alone

d. copper T (loop) no relation

e. condoms (for men)

@81) Patient take DMARDs and after 2 weeks have eye problem
which drug cause that:

a. sulfalazine

b. hydroxychloroquine

*@82) pro-kinetic drug has anti emetic effect:

a. domperidone

b. *Cisapride
*@83 )Treatment for influenza A and B, cleaves sialic acid (or something like
this)
One of the answers was Oseltamivir=tamiflu

*@84 -pateint come to pharmacy asked about his hand , he have gray
burrow's on web ......

a.*scabies

B.psoriasis

Note: know Differential diagnosing

*@85 . The metabolic effect of combining glucocorticoid and tacrolimus is:

a. Hypocalcemia

b. Hyperglycemia

c. Hyperlipidemia

d. Hyponatremia

*@86. Which antiplatelet cause blood disorder (agranulocytosis, thrombocytopenia)

and a type of anemia) aplastic anemia:

a. Ticlopedine

b. Clopidogril

c. Aspirin

d. Abciximab

*@87 . Patient has HIV, which NRTI cause lactic acidosis and hepatic steatosis:

a. Zidovudine
b.stavudine

*@88 -negative symptoms apathy and blunted are benefited with:

A.Respiridone

b.Haloperidol

c.fluphenazine

D.chloropromazine

*@89- .short acting TTT in asthma case

A.salbutamol = acute asthma (emergency)

B.Albuterol = acute asthma (emergency)

1st line: Albuterol
2nd line: Salbutamol or terbutaline

*@90- Which part in aerosol press on valve:

a. Actuator

b. House

c. Dip tube

that’s all I can remember , good luck and have a nice day

‫دعواتكم‬

Dr. Muhamed Tarek Agwa

Don’t forget to take ur Passport plus another ID for the exam .

19/2/2019

‫بسم الله الرحمن الرحيم‬

10/1/2018( ‫مكرر من امتحان‬19/2/2019 (‫ دا امتحاني‬,‫(السالم عليكم‬
‫الحمد لله االمتحان سهل جدا جدا متقلقوش مش بتاخدوا اى حاجه معاكو وال آله حاسبه وال اي حاجة‬
❤❤ ‫في آله حاسبه ع الكمبيوتر وبالتوفيق للجميع‬
Q1. Aspirin overdose symptoms are all of the following except:
a. Hypothermia
b. Metabolic acidosis
c. Respiratory depression (hypoventilation: a breathing disorder characterized by slow
and ineffective breathing.)

My notes:
Overdose SMx: The earliest symptoms of acute aspirin poisoning may include ringing
in the ears (tinnitus) and impaired hearing. More clinically significant signs and
symptoms may include rapid breathing (hyperventilation), vomiting, dehydration,
fever, double vision, and feeling faint.
Later signs of aspirin poisoning, or signs of more significant poisoning, include
drowsiness or confusion, bizarre behavior, unsteady walking, and coma.
The abnormal breathing caused by aspirin poisoning is usually rapid and deep.
Vomiting may occur 3-8 hours after taking too much aspirin. Serious dehydration
may occur from hyperventilation, vomiting, and fever. Aspirin poisoning signs and
symptoms can range from minor to severe.
References:https://www.emedicinehealth.com/aspirin_poisoning/article_em.htm#a
spirin_poisoning_symptoms

Q2. Mechanism of action and indications of aspirin:

1) Irreversible cox inhibitor, 2) Inhibit platelet aggregation, 3) PG inhibitor

Q3- Patient with gout history present to ER with gouty attack, which NSAID is
contraindicated:
Aspirin
Note: The best NSAIDs to use with gout are: ibuprofen 800 mg TID and Indomethacin 25 to
50 mg QID

Q4- Picture of nail with thick texture and brown discoloration, Nail fungal infection
DOC:
a. Fluconazole
b. Terbinafine
c. Griseofulvin

Note: According to the British Association of Dermatologists, the guidelines goes by

terbinafine OR itraconazole in the first line

Q5- Insulin that cannot be given as an IV:

a. Lispro ( rapid acting ..... .> short -acting )
b. Aspart ( rapid acting )
c. Glulisine ( rapid acting )
d. humuline (=isophane)( intermediate acting )

Q6-which Insulin type that's its reaction time is not effected by site of
administration:
Glargine (lantus)
Detemir

Q7- Comparison between Acyclivir with Valacyclovir:

Greater bioavailability

Q8- Acyclovir is not effective in which virual infection? The options are NOT diseases
but viruses names!
a. Herpes zoster
b. Epstein-barr virus
C.CMV
d. herpes zoster

Q9- Type of penicillin that cannot be administered IV:

a. Penicillin G
b. Penicillin V
c. Others two options

Q10- Which iron dose is questionable:

a. 120 mg for 20 kg child
b. 90 mg for 15 kg child
c. 21 mg for 7 kg infant
d. 30 mg for 6 kg infant

Q11- Female is menopause, she experiences hot flushes, developed spinal osteoporosis
which to use?
Alenderonte
Note :If there is no alderonate in choices, the answer will be (estrogen and progesterone)

Q12- Lactating mother wants to use contraceptive which cannot be used:q19

a. Progestin alone
b. combination
c. copper T
d. condoms

Note: Estrogen only 1st CI

Combination 2nd CI

Q13-ACEI’s beneficial effect is caused by all of the following mechanisms except:

Vasodilation by inhibition of bradykinin metabolism

Q14- Patient taking ACEl (ramipril) which antacid should not be used:
a. Calcium carbonate
b. Magnesium
c. Aluminum
d. Potassium bicarbonate

Q15- Sulfasalazine prevents the absorption of which element?

F olate

Q16- Sulfasalazine should be given with which supplement?

Folic acid

Q17- Which is not given for constipation:

a. Lactulose (constipation)
b. Loperamide
c. Na-picosulfate (constipation)

Q18- New born infant had an infection he was given medication and kept under
supervision; after 6 days he developed depressed breathing, gray coloration and rash,
which drug is most likely he's on?
Chloramphenicol (cause hemolytic anemia, protein synthesis inhibitor 50s subunit)

Q19 Female taking UTI medication, after few days she developed rashes and red spots on
hands, face, (they mean to say exposed areas) what medication she's on? They attached a
hand that shows red spots with the question.
ciprofloxacin👈, ttc, acyclovir, amiodarone, diuretics)

Q20- A Kid took peanut butter and he’s allergic to peanut; he developed rashes and
urticarial. What type of allergic reaction is this?
a. Type 1
b. Type 2
c. Type 3
d. Type 4

21- Read about Acetaminophen (paracetamol) full mechanism of action, and its effect in
Reyes disease in kids with fever related to viral infection. you can choose more than one
true statement.
a. Acetaminophen has a great anti-inflammatory
b. inhibit PG in CNS
c. It has no risk in Reyes disease for kids with viral fever
d. irreversible cox3 inhibitor

22- Not a side effect of (ACEIs) ramipril:

a. Hypokalemia
b. Low level of potassium

23- All of the following cause constipation except:

a. Bisacodyl
b. Morphine
c. Calcium
d. ACEI

24- Medication in an Inhalation route, can be used for long term to control asthma:
a. Salmetrol
b. Budesonide (Inhaled corticosteroids)

25- Which of the following is not used in TB treatment

a. INZ
b. Refamp in
c. Streptomycin
d. Ethambutol
e. PZN

26- patient with TB take more than one drug why??

To decrease the risk of developing drug-resistance

27- When giving ethambutol for a long duration, continuous follow-up/check-up is

necessary because of this condition:
a. Renal failure
b. Liver dysfunction
c. vision problem
28- DOC in bacterial meningitis:
Cefuroxime.
Note: Bacterial meningitis > Antibiotics as 3rd generation cephalosporin ( cefuroxime,
cefotaxime, ceftriaxone) and vancomycin may be added. Penicillin plus chloramphenicol

29- Patient was found to have an infection with gram +ve and -ve, which drug to use? We
have to choose a broad spectrum antibiotic
Amoxicillin

30- Pregnant woman with hypertension, what is the drug of choice?

Methyldopa

32-What is the medication that’s used in the treatment of glaucoma, medication-related

edema, heart-failure related edema?
Acetazolamide

33- Patient on three medication for HIV, after couple of years there is still evidence of
infection, enfuvirtide added to them which of the following is true:
The answer was the one that include the mechanism of action of enfuvirtide and how it’s
taken(SC).
They asked also about its low side effect profile and its reconstitution study them.

Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 subunit of the
viral envelope glycoprotein and prevents the conformational changes
required for the fusion of viral and cellular membranes. It works by
disrupting the HIV-1 molecular machinery at the final stage of fusion
with the target cell,
preventing uninfected cells from becoming infected. Enfuvirtide is a
biomimetic peptide that was rationally designed to mimic components of the
HIV-1 fusion machinery and displace them, preventing normal fusion.
Enfuvirtide is an antiretroviral drug used in combination therapy for
the treatment of HIV-1/AIDS.

34- What is the antiviral that’s the most suitable for HSV infection? Get a general idea about
HSV viral infection please
Acyclovir
35- Pharmacist monitoring of drug despising and refill will give an idea about:
a. Drug utilization
b. Drug disposal
c. Drug adherence

36-What’s the type of study that’s MOST reliable?

a. Cohort randomized
b. Case study
c. Case report
d. Case scenario

37- What’s the type of study that’s LEAST reliable? Memorize types of studies please
a. Cohort randomized
b. Case study
c. Case report
d. Case scenario

38- Manufacturer recall of medication from pharmacy is called:

Voluntary call

39- Approved duration for the use of tamoxifen is:

10 yrs
40- DOC for status epilepsy:
Diazepam
Note: 1st → Diazepam 2nd → lorazepam/midazolam 3rd → phenytoin

41-patient with panic attack what is DOC

a. buspiron
b. benzodiazepan
c. antidepressant
d. barbiturate

42- benzodiazepines are all except:

a-anticonvulsant
b-muscle relaxant
c-Antero amnesia
d-anti pscychotic

43- Patient has a problem in bowel emptying, he develops pain while passing stool. Which
is the least likely condition to cause this problem?
Hyperthyroidism
44- Patient take DMARDs and after 2 weeks have eye problem, Which DMARD related to
vision problem:
hydroxyquine

45- Patient present to ER because of gouty attack, he was given NSAID, when should we
consider giving prophylaxis therapy for gout: ((you can choose more than one))
- more than One attack per year
- Association with Kidney stones
- Urate excretion more than 500 mg
-Uric acid more than 10mg

46- Digoxin cannot be used in which condition:

a.Heart failure
b.Along with ACEI and diuretics
c.In ventricle atrial fibrillation
d.Left diastolic HF

47- All of the following are indications of diabetes except:

a. Polyuria and unexplained weight loss
b. Random blood glucose of 200
c. Fasting blood glucose of 140
d. Blood glucose level of 200, 2 hours post oral glucose intake

48-insulin secrets form which cell ?

B cell

49-All can resist Beta lactamase except:

a.Augmentin
b.Doxcycycline
c.Dicloxacilln
d.Azythromycin

50- Study acetyl salicylic acid full mechanism of action as an analgesic and cardio
protective.
Acetyl salicylic acid (aspirin)characterized by :
● cardio protective action
● Has antiplatelet action
● Analgesic and antipyretic
● Can't arrest rheumatoid arthritis
Answer 1&2&3
51-which drug has least effect of hypoglycemia:
Metformin

52- Azathioprine SE not dose related:

Infection

Q53- which of the following no need for antibiotic dose adjustment ?

a.hypercholestrylemia
b.elderly patient
c.renal disease patient
d.AIDS

Q54- Patient with TB has discoloration in urine (reddish color) on which medication?
Rifampicin

Q55- patient on cyclophosphamid has developed hematuria due to release of which :

a. phosphoramide mustard
b. Acrolein
c. Mensa

Q56- Which is true about Digoxin MOA is:

Positive inotropic effect

Q57 drug given for ductus arteriosus:

Indomethacin

Q58- which of the following cause depression in T-lymphocyte:

abatacept, alefacebt, sirolimus baciliximb, daclizumab (check please)

Q59- Which of the following S.E of B2 agonist?

a. Hypokalemia
b. Hypomagnesia
c. Tremor

Q60- Patient has irritable bowel disease, the doctor advice the patient to remove dairy
products from his diet, which symptoms patient have:
a- chronic Constipation
b- chronic diarrhea
Note: dairy products cause constipation

Q61- Etoposide cause DNA damage through inhibition:

a. Topoisomerase I
b. Topoisomerase II
c. Topoisomerase III
d. Topoisomerase IIII

Q62- prostaglandin that can be used for glaucoma and eyelash Hypotrichosis
a. Lantoprost
b. Travoprost
c.bimatoprost
d. tafluprost

Q63- Acyclovir MOA:

a. DNA polymerase

Q64- micro-organism resistant mechanism against antibiotics:

Enzymes

Q65- Aortic dissection DOC along with B blocker:

Sodium nitroprusside

Q66- Antibiotic that cause hand rash:

cipro

Q67- Patient diagnosed with hodgkin lymphoma. Doctor decides to stop him from dairy
product. Which amino acid patient will avoid:
Tyramine

Q68- 5 days old infant given antibiotic which cause apnea and gray coloration for the
baby?
Chloramphenicol

Q69- smoker with COPD , what is the drug of choice ?

a. Busonide
b. Ipratopium
c. Theophyllin
d. Montelukast
Q70- A physician wants to switch a terminally-ill patient from slow release morphine
sulphate tablets, 15 mg twice daily, to a liquid morphine sulphate dosage form because the
patient has difficulty in swallowing tablets. If a morphine sulphate solution containing 5 mg
per mL is prescribed q4h, what volume should be dispensed for a 20 day supply to provide
the same pain relief as the tablet regimen?
a.20 mL
b.60 mL
c.100 mL
d.120 Ml
‫المسألة الوحيدة في هذا األمتحان عقبالكو‬
😂😂😂
Q71-Action of insulin except:
Decrease glucose production in liver
Decrease liver glucose uptake
Insert glucose in muscle and adipose tissue

Q72- Which is contraindicated with sulfa sensitivity

Celecoxib

Q73- Selective cox 2

Celecoxib

Q74 Pentation through CSF )cerebrospinal fluid( depends on all except:

a.Lipid soulibility
b.Water soulibility
c.Mwt
d.protein binding

Q75-female take antibiotics and suffer from ear problem which AB cause this:
Amikacin

Q76-used in motion sickness except:

Cinnarazine
Hyoscine
Scopolamine
Promethazine HCL
propmide👈

Q77- Study heparin mechanism of action.

injectable anticoagulant mechanism of heparin:
-inhibit platelet aggregation
-potentiate antithrombin 3
Sorry dont remember answer

Q78- Not ACEIs SE:

Hypokalemia

Q79-which of the following if administered with digitalis will not affect its action:
Ciclosporin(please check)

Q80- Patient was diagnosed with malignant glioma and doctor decides to put him on
chemotherapy. Which of the following is DOC:
Carmustine
Q81- Cyclosporine SE will increase if given in which route:
IV

Q82- Study letrazole mechanism of action and side effects, you can choose more than one
answer.
aromatase inhibitor with no androgen Side effects.

Q83- True about SSRI:

Safest one to use for long term.

Q84- Used in emergency HTN:

Na nitroprusside

Q85- Associated with CNS side effects:

Mefnamic acid

Q86- Which of the following causes tachycardia:

a.B blocker
b.verapamil
c.diltiazem
d.isosorbide dinitrate

Q87- patient with ED (erectile dysfunction) and take Sildenafil which CI with sildenafil:
isosorbide dinitrate

Q89- Not to be used in Chrons disease:

a. Adalimumab
b. Certolizumab
c. Etanercept
d. Another biological treatment

Q90- Which not used in heart failure:

Captopril
Digoxin
Nefidipine
Propranolol

Q91- Cromylin used in asthma to :

Decrease inflammation
Mast cell stabilizer

Q92- patient have hair loss (bladness) ‫ الصلع‬, the doctor give him topical treatment is:
Minoxidil ‫ دا كان‬case patient notice a bald line in his head

Q93- The DOC for acute attack of asthma:

Albuterol

Q94- patient came to the pharmacy and have chest pain, the pharmacist decide to turn the
patient to cardiologist because:

The pain radiating on neck and shoulders, arms and jaw

Q95- The best advice to a patient taking corticosteroid inhaler for asthma (you can choice
more than 1 choice)

a) Take rapid breath after pressing the inhaler

b) Hold your breath for 10 seconds after complete inhalation

c) rinse your mouth with water after using the inhaler

d) keep one finger distance between your lips & the inhaler

Q96- Patient was on cyclosporine and changes to tacrolimus. Tacrolimus comparison

with Cyclosporine: (you can choice more than 1 answer)
a. more potent
 b. Less side effects (less nephrotoxicity )
c. longer duration
All true except

Q97- All are true about benzodiazepine except:

● Cause amnesia.
● Cause muscle relaxant.
● Anti psychotic👈

Q98-pregnant women with Uti Doc

Cephalexin

Nany ahmed ‫👐 ال تنسوني من صالح دعائكم وبالتوفيق والنجاح للجميع‬

19-3-2019

My exam was repeated from 24-12-2018

Vidhya 2019 HAAD EXAM

1. Pt with hypertension and gout which antihypertensive drug suitable for him ?

1/chlorthiazide

2/torsemide

3/metolazone

4/tenormine

2. Pt. with hypertension and CHF with ejection fraction 28%, which anti hypertensive suitable for
him?

a) clonidine

b) guanithidine

c)diltiazem
d) nislodipine

3. case about a patient came to emergency with high blood pressure and they gave him o
minoxidil what the Mechanism Of Action :

A-decrease HR and decrease contractility

B-decrease arterial pressure and increase contractility

C-Increase HR and increase contractility.

4. Drug of choice for hypertension in pregnancy.

Labetalol (methyldopa not in option)

5. Common side effect of arrhythmia drug?

Torsade de point

6. Patient with blood pressure 190/110 and glaucoma which drug should be avoided

A- labetalol

B- fendolapam

C- Na Nitropurroside

D- Nitroglycerin

7. case about patient have lowered HDL and little elevation of LDL ?

-niacin

-fenofibrate

-colesevelam
8.atrovastatin 10mg =20 mg simvastatin

9. simvastatin causes serious interaction with☹(repeated 2 times same question)

A- amiodarone

B- verapamil

C- aspirins

10. all of the following drugs cause postural hypotension except:

A- clonidine = alpha blocker

B- carvedilol

C- sildenafil = alpha agonist?

D- clozapine

11. Patient with hypertension and renal failure which diuretic suitable for him:

a. Chlorthiazide

b. Triametrene

c. Furosemide

d. Spironolactone

12. bumetanide true about it :

a. Need potassium treatment with it

b. Contraindicated with sulphonamide sensitivity

c. All of the above

13. Propanolol not used in:

partial AV block

14.Which of the following cause hyperinsulinemia

A-Pioglitazone

B-Glimipride

C-Metfotmin

D-Acarbose

15.Lady came to a pharmacy having dysmenorrhea , complaining about severe pain , and her
period came week later than she expected , the pharmacist decided to refer her to doctor because
of :

A-Ectopic pregnancy

B-Fibromyositis

C- Pelvic inflammation

D-Endometriosis

16.Case about a patient took lovastatin all of the following are side effect except:

A-myopathy

B-rhabdomyolysis

C-renal dysfunction

D-hepatic dysfunction

17.Erythropiotin known as increase hemoglobin … etc which following not used in

A-severe anemia due to acute bleeding

B- something about cancer related

18-case about a patient had an organophoshorous toxicity , all of the following are side effect
except:

A-Cyclopegia

B-Miosis

C-Skeletal muscle weakness

D-GIT disturbanceca

19.Controlled drug used for pain during acute MI

A-naproxen

B-celcoxib

C-morphine

D-bethidine

20-Case about a patient came to emergency suffering from hard breathing for the last 30 min and
she has family history of asthma which is suitable:

A-Sulbutamol

B-Salmeterol

C-Ipratropium

D-albuterol

21-which can be used for long term

A-Albuterol

B-Ipratropium
C-Salmeterol

D-Corticosteriods

22-which of the following doesn’t cross CNS :

A-Carbachol

B-Physiotgmine

C-Neostigmine

D-Bethanecol

22-Which of the following if used for long term can increase acetaminophen toxicity:

A-Verapamil

B-Cimitidine

C-Ethanol

D-....

23.Case of a patient asked for an OTC for her constipation, she said that she experienced painful
defecation . you decided to transfer her to a physician because you think she have

a.Anal fissure

b.Anal fistula

c.Rectal fissure

d.Rectal aabscess

24patient came to pharmacy and bought a UTI indicator test, which of the following is true?

A.it’s a test that convert dietary nitrite to nitrous

B. it’s a test that indicate anaerobic bacteria only

C.it’s a case that indicate gram positive bacteria only

D.it’s a kit that contains 30 dipstick in a packet

25-A Patient having Herpes simplex which of the following doses is true :

A)ACYCLOVIR 200 mg 5 times daily

B)ACYCLOVIR 400 mg 5 times daily

C)ACYCLOVIR 800 mg 5 times daily

D)ACYCLOVIR 100 mg 5 times daily

26. Which fibrinolytic cause hypersensitivity:

Altepase= fibrin selective

Fondaparinux

Streptokinase= fibrinolytic

Urokinase

27. Which antiplatelet cause agranulocytosis, thrombocytopenia and aplastic anemia :

A-ticlopedine

B-clopidogril

C- aspirin

D-abciximab

28.If drug is taken by incorrect route , what will happen :

A-ineffective

B-toxicity
C- drug interaction

D- omission of doses

1)a,b,c

2)a,b

3)b,c

4)all

29.The metabolic effect of combining glucocorticoid and tacrolomus is :

A-hypocalcemia

B-hyperglycemia

C-hyperlipidemia

D-hyponatremia

30.Semi control drugs :

a. CD A

b. CD B of group 3

c. CD B of group 5

d. narcotic drugs

31. Refregirator temperature of medicine

0–2

2–8

2 – 10
8-15

32.Sodium laulryl sulfate is used as?

Antifoaming agent

Antioxidant

Solublizing agent

Preservative

33.Expiry of inhaler

3months from opening with proper storage.

9 months

1 year

34.normal prescription valid for

No limit

6 month

9 month

1 year

35.medicine that are sensitive to light should be put in

Amber container

36. Which of the following gases used as propellant in aerosol container???

A-carbon dioxide
B_hydrocarbon

C_trifluromethane

D_all

37. Which part of the can considered as the heart of the can ?

A.valve or actuator

B.propalent

C.tube

38.Which part in aerosol press on valve:

a. Actuator
b. House
c. Dip tube

39.Morphine can be dispensed in:

A) regular prescription prescribed by psychologists
B) registered prescription prescribed by psychologists
C) narcotic prescription prescribed by psychologists
D) narcotic prescription prescribed by a licensed pharmacist

40.which of the following is DOC in the treatment of Diabetes Insipidus (polyuria and polydyosia
leading to dehydration and seizures)
A-Vasopressin
B-Desmopressin
C-Gliclazide

41-Which of the following cause hyperinsulinemia

A-Pioglitazone (thiazolidinediones, enhance insulin sensitivity, cause weight gain and CI in HF)
B-Glimipride (stimulate insulin secretion, cause hypoglycemia)
C-Metfotmin (biguanides)
D-Acarbose (a-glucosidse inhibitor)
42’-Which of the following cause hypoglycemia EXCEPT
A-Pioglitazone
B-Glimipride
C-Metfotmin
D-Acarbose

43.and also a question about where histamine is stored in the GIT

A-Basophiles
B-Parietal cells

44-mechanism of action of metformin except (increase insulin sensitivity, decrease LDL AND TG,
increase HDL, doesn’t cause hypoglycemia:

A-increase insulin sensitivity

B-increase HDL and decrease LDL something like that
C-inscrease insulin secretion

45.Metformin other uses than diabetes:

Polycystic ovary syndrome

46-Case of a child having diarrhea, he had 2 bowel movements within 3 hours, what should you
give?
a.loperamide
b.ors
c.antibiotic

47-physiological mediator for acid secretion in stomach :

A. Gastrin
B. histamin
C. Muscurinic
D. vagal response(doubt I choose )

48.In filteration ophthalmic atrophy due to : (also known as thorid eye disease, that results from
edema and lymphocytic infiltration of orbital fat, connective tissue, and eye)
A.Hyperthyroiditis
B.Toxic unilateral goiter
C.toxic bilateral goiter
D. Graves disease

49-Pregnant woman having UTI which of the following drugs can be used
A-Nitrofurinatoin(doubt)
B-CO-amoxiclav
C-Sulfamethoxazole—not safe in 3rd as cause kernecteis- not be given in G6PD, given in ``1st and 2nd
trimester
D-Trimethoprim—not safe not be given in G6PD

50.UTI in Pregnancy with G6PD >> cefuroxime

51.mitochondrial toxicity,, ANTIVIRAL used:

a-lamivudine
b-amatidine
c-zidovudine
(N.B. : 1- Stavudine 2- Zidovudine

52.case for Tb and leprosy he had big wound in his hand with very thick skin and no sensation. In
the wound he can use all these drug except:
A. Rifampicin
B.INZ
C.OFLOXACIN
D. ropranolol

53-which is caused by staphylococcus aureus or streptococcus pyogenes:

Impetigo

54.Patient has pain in his left eye and he sees halo around light
A.Glaucoma
B.cataract

55. Patient comes to pharmacy with itching and redness between fingerwebs , you notice a grey
line :
A-atopic eczema
B- psoriasis
C-dermatitis
D-scabies

56.Which of the following can be used for long term treatment

Salmetrol
Albutrol
Ipratropium
Corticosteroid

57.case about patient has difficulty in breathing at the last 30 minute , his family is asthamatic and
he has experienced asthma ,what is used for decreasing ropranolo
A.salbutamol
B.Albuterol
C terbutaline
D corticosteroid

58.Which of the following will increase the half-life of theophylline?

a): Carbamazepine
b): Cimetidine
c): Phenobarbital
d): Smoking (wrong as increase its metabolism)

59-Hypercapnia management :
a. doxapram
b. disopyramide
c. dopamine
d. Ipecac

60-The metabolic effect of combining glucocorticoid and tacrolimus is (eczema atopic dermatitis):

a. Hypocalcemia
b. Hyperglycemia
c. Hyperlipidemia
d. Hyponatremia

61.Which of the following is true?

A.Aspirin used as anti inflammatory, antipyretic , and as a prophylaxis for secondary MI
B-paracetamol is used as an analgesic, antipyretic, and as an antiplatelet in small cocentrations
C-diclofenac is used as analgesic , antipyretic , used as antiplatelet in small concentrations

62.Which of the following if used for long term can increase acetaminophen toxicity:
A-Verapamil
B-Cimitidine
C-Ethanol
63.All irreversible except.
A. Malathion
B. Ecothiophate
C. parathion
D. piperzidine

64.Sumatriptan is
*5-HT agonist & not used in coronary artery diseases, patient may suffer from another attack after
the first dose
*5-HT antagonist + same as A
*other 2 choices start with 5-HT antagonist + ..........................

65.Phenoxybenzamine is irreversible adrenergic antagonist used in:

A-HTN
B- BPH
C- pheochromocytoma

66.Anti cholinergic used for motion sickness :

1- scopolamine DOC
2- ipratropium
3-…………..

67.Case of patient having Parkinson disease,

This patient is talking selegiline , this drug should be taken along with
A.levodopa
B.carbidopa
C. ropranol

68.case about a patient had an organophoshorous toxicity , all of the following are side effect
except:
A-Cyclopegia
B-Miosis, increase saliva, tear production
C-Skeletal muscle weakness and tremors
D-GIT disturbance (diarrhea and vomiting)

69-which one of the following is true about botulinum toxicity :

A-Acetylcholieterase receptors blockade
B-Treated with choline infusion
C- act on preganglionic ends

70- epinephrine cause all except:

increase systolic pressure
hyperglycemia....
Lipogenisis

71- All of the following are uses of cholinergic agonist except:

a. Glaucoma
b. Atony of bladder
c. Megacolon
d. Sjogren’s

72.Clozapine blocks which receptor (s):

a. Serotonin
b. Dopamine
c. Serotonin and dopamine
d. Dopamine and norepinephrine

73.-The anxiolytic of BZD is usually attributed to their ability to do which of the following
a. Potentiate the effects of GABA
b. Alert the sodium ion influx
c. Alert the calcium ion influx
d. Interfere with amine

74.-Benzodiazepines
A-blocking of GABA
B- something related to insomnia
C-have high therapeutic index
D-all are lipid soluble

- 75.Droperidol:
A. Substituted phenothiazine
B. Reliably produces mental tranquility
C. Does not act (directly) on CTZ
D. Alpha-blockade with hypotension is not a problem with 2mg dose
E. Slows alpha rhythm on EEG

76-cholinergic toxicity case work in which receptor:

A.muscarinic (cholinergic)
B.nicotinic
C.adrenergic
D.nor adrenergic
77.negative symptoms apathy and blunted are benefit with:
A.Respiridone
b.Haloperidol
c.fluphenazine
D.chloropromazine

78- the least effect of norepinephrine on which receptor

Alpha 1
Alpha2
B1
B2
79.vertical laminar flow hood cleaned by –alcohol

80.Used to treat impetigo

i Fusidic acid
iiAzithromycin
iiiMupirocin
1.i,ii,iii
2.i,ii

3.i,iii

81.patient using spacer with meterd dose inhaler,

Hold the breath for 10 sec after complete inhalation

Ask him to rinse mouth with water

82.which of the following reduce the progression of COPD(repeated 2 times by different way)

Ipratropium

Salbutamol

Corticosteroids

83.liraglutide is

GLP

84.tamoxifen not used in

Advanced breast cancer

85.how to differentiate kidney failure and kidney transplant rejection.

Glomerular filtration rate

Serum creatinine

Biopsy

86.all of the following drugs should be avoided with azathioprine except

ropranolol

87.how to differentiate between cholinergic crisis and myasthenia crisis.

Edrophonium test

88.tazobactum –b lactamase inhibitor

89.patient take theophylline as ttt,what is ur advice

Donot crush

90.about junior pharmacist asked to refill prescription of morphine

It need controlled prescription should be written with licensed prescriber.

91.clindamycin calculation -150mg every 6 hr

92.heparin calculation …..

93.60% bioavilabilty to 70%

94.child 6 month weight 3lb7oz

19-4-2019

It’s not there, but it’s repeated from 2-7-2017

* 9 /6/ 2016 ( ** ) ‫الحمدالله سهل ومكرر من امتحان‬7 /2 /2017( ) ‫امتحان‬

1- A case associated with hepatic failure ?

Ascites
2- Vaccine for elderly people that is given yearly for respiratory
infection ?
- Haemophilus influenza vaccine
3- Vaccine which is given for old patients every year for respiratory
infections ?
- Haemophilus influenza vaccine
4- Which of the following need vertical laminar flow ?
- Doxorubicin
5- Which of the following doesn't need horizontal laminar flow?
- doxorubicin
6- Shortest half life time?
- erythromycin
7- Lomotil is a mixture of Atropine and?
-diphenoxylate
8- Aspartam not given with patient who has ?
- phenylketonurea
9- Patient take 220mg anhydrous znso4 to receive amount of
elemental zn ,how
many mg of znso4)7h2o (have to take )?mwt of zn 65 ,mwt of znso4
161 ,mwt of h20
18(?
- Answer=392
10- patient received morphine 20mg every 4hr .if we want to shift to
MST continous
tab .what is the dose?
- Answer =60mg BID
11- A physician wants to switch a terminally ill patient from slow
release morphine
sulphate tablets 15mg twice daily ,to a liquid morphine sulphate
dosage form
because the patient has difficulty in swallowing tablets .if a
morphine sulphate
solution containing 5mg per ML is prescriped q4h ,r what is the
volume should be
dispensed for 20 day supply to provide the same pain relief as the
tablet regimen?
- Answer=120 ML
12- Patient is using dopamine infusion 2.5mcg\kg\min ,how many ml
of dopamine
patient will consume if dopamine ampoule conc .is 0.8mg\1ml within
24hrs
- Answer=360ml
13- Sumatriptan ,which is true?
IF headache is not relived and another attack occur after 2 hrs take
another tablet
14- For chronic allergic rhinitis we use?
-beclomesathasone inhaler
15- Corticosteroid inhaler which advice is true ?
a-rinse mouth with water
b-hold breath for 10seconds after complete inhalation
c- both
16- Which advice is an indication of good control of asthma with a
child ?
- There are 2 inhalers one at home and another one at school
17 -patient is 75 years old who has just been diagnosed with
hypothyrodism
Patient should be start levothyroxine in a low dose because of her ?
- age
18- Appropriate counseling and follow up for patient with initiation
of levothyroxine includes all of the following except ?
- Take levothyroxine on a full stomach for greater absorption
19- which 0f the following parameters is the most appropriate for
patient self
evaluation of effectiveness of levothyroxine therapy?
- Increased energy
20- in 24 hrs pharmacy we need ?
- 3 pharmacists and unlimited number of assistants
21- which elevates first at acetaminophine over dose ?
- ALT
22- About missed or broken ampoule ..how to keep them in haad
section in
pharmacy?
- use the facility incidence form
23- case about patient take cefuroxime and celecoxib and have
diarrhea what is the cause?
- Post antibiotic pseudomembraneous colititis and patient have to
see the doctor.
24- case about patient who takes clindamycin and losartan ..have
diarrhea what isthe cause ?
- Due to clindamycin… patient must see the doctor
25- patient have constipation and take mineral oli for many days
what u should
advice him for?
- U must see the doctor to know the cause of constipation
26- patient need to refill prescription but the dose is not appears
clearly what u
should do?
- Call the doctor and ask him about the dose
27- which is true about laxatives :
- paraffine should be avoided as it cause pneumonia
28- community accqired pneumonia which is its cause ?
a-mycoplasma pneumonia
b-influenza
c-both
29- About fiber cone which is true?
a-take it with plenty of water
b-its used for diarrhea and constipation
c-it is avoided with tetracycline
d-all of the above
30- Antidote for cloroquine over dose:
- Diazepam
31- Which of the following is not a sign of taking cocaine ?
-peripheral vasodilatation
32- which is not side effect of Salbutamol?
-constipation or hyperkalemia
33- Which is taken orally for influenza?
-seltamivir
34- which is opiod agonist?
- Tramadol
35- case of high frequency of urination with no pain and patient has
polydyspepsia
and polyphagia … this is due to?
- Diabetes mellitus
36- which is considered narcotic in UAE?
- Methyl phenidate 5mg
37- which is not true in the following?
- Diphenhydramine is the drug of choice of morning sickness
38- give cefuroxime 750mg IM stat?
-give recommended dose with out a delay or immediately
39- the dose of the drug is 5mg\kg\day in divided doses,how many
mg of this drug that the patient will take it twice daily ..patient
weight is 176 IB
ANSWER=200mg
40- Ephedrine is contraindicated with antidepressant from which
class?
- Mono amine oxidase inhibitors (MAOI)
41- Which of the following will be side effect of atenolol with
prolonged use?
- Fatigue
42 -Oxymetazoline nasal spray cause?
- Increased heart rate
43- pediatric patient on regular cimetidine 125mg\every 6hrs .he is
using 125mg\5ml and the available stock is 250mg how many mls
will you give from the stock per dose?
Answer=2.5ml
44- What is the pore size for cold sterialization?
- 0.22micron
45- what is the lowest degree in refrigerator ?
-2C
46- to prevent recurrent myocardial infarction we use?
- Aspirin
47- case about patient forgets to take her metoclopramide dose for
nasea and
vomiting after chemotherapy ...what u should advise her?
- Skip the missed dose and take the next scheduled dose at lunch
time
48- which is caused by staphylococcus?
- Impetigo
49- patient take Acyclovir for cold sore how many times should
apply it?
- 5 times
50- which of the following is more potent corticosteroids?
- Clobetasol propionate
51- which cause thrush ?
- Amoxacillin
52- Alprazolam is?
- Short acting benzodiazepines..controlled drug
53 -Storage of alprazolam controlled drug?
- Steel cupboard well locked
54- Patinet is taking hydrochlorothiazide \amiloride …which interact
with them ?
- Enalapril
55- Saline flush is used for?
- Small volume of saline is used to flush active drug into circulation
56- NOT used in dandruff?
- permethrin
57- which of the following medications is taken with or after food ?
- Prednisolon
58- Which of the following is not true about simvastatin?
- Take the dose with breakfast
59- which drug has enzyme inhibition on its first action?
- Enalapril
60 -A drug with t1\2 3hrs ,how many of this drug will remain in the
body after 24 hrs? -
Answer=less than 1%
61- Which is used for hyper ammonia?
a-Duphalac
b -Contulose
c -Enulose
d -ALL of the above
62- Inderal is generic name for?
- Propranolol
63- High volume of distribution means ?
- High tendency to bind to tissues
64- If the bioavailability of drug is decreased due to interaction with
other drugs
what is true?
- Higher doses is needed
65- About handling anticancer which is not true ?
- Use positive pressure in withdrawing solution from vial
66- What is the infusion rate if conc .Of drug in blood is 10ug\ml and
clearance rate is
0.25\hr and vd is 12 litre
- Answer=30mg\hr
67- which is associated with symptoms before rash and lesions?
- Cold sore
68- Which have narrow therapeutic index?
- Heparin ,warfarin,vancomycin
69- which route of administration is not used with parenteral
suspensions?
- IV
70- which advice is given with clarithromycin suspension?
- Shake well before use
71- Treatment of otitis media?
- Local analgesia
72- which is not altered of the prodrug?
- Potency
73- Infectious mononeocleosis caused By ?
- Epastin Barr virus
74- Epastin Barr virus affects who of the following ?
- teenagers
75- Iron decrease absorption of which?
- Moxifloxacin
76- 100ml of infusion contain 10mg of 2%drug what is strength of
infusion ?
Answer =2mg\ml
77- case about patient takes enalapril and simvastatin and has dry
cough what is the cause of that?
- Enalapril
78- Patient is checked with pneumonia . .What is the pathogen that
causes it and the best treatment?
- Mycoplasma pneumonia ..treatment is Macrolides
79- which is used in neuropathic pain more than norceptive pain?
- Nortriptylline
80- Patient has glutamate allergy .he suffers from?
- Caeolic disease
81- Which of these drugs have only one enantiomer?
- Escitalopram
82- Patient with allergic conjunctivitis using lenses which is true ?
Neither gas permeable lenses nor soft lenses should be used during
applying the drops .
83- Metformin prevelant factors?
a- renal disease
b- hyperthyrodism
c - both
84- Does not cause myopathy ?
- Cholestyramine
85- In which case gentamycin will not be toxic ?
- If plasma conc .Is less than 2mg\ml
86- Beta lactamase producing bacteria which is effective against it ?
-cefipime
87- medication for Prophylaxis of migraine for patient with
electrophsyscosis ?
- amitriptyline
88- Mechanism of action of digoxin is?
- inhibit Na/K atpase pump
89- A drug that has high risk for thrombosis and MI?
- celecoxib
90- Drug used in atheltes foot;nystatin?
a. griseofulvin
b. clotrimazole
c. both
91- what is the physiological antagonist of histamine?
- Epinephrine
92- Drug of choice in treatment of hypothyroidism?
- levothyroxin
93- COPD patient taking beta agonist and corticosteroid, but his
asthma is still
not properly controlled, which of these drugs should he add to his
regimen?
- Ipratropium
94- succinylcholine metabolism?
- ester hydrolysis

19/5/2019

Dr/Eman Hassan

‫ وال ال‬EXCEPT ‫ اهم حاجة نذاكر كويس وناخد بالنا من السوال فية‬2018 ‫االمتحان سهل مكرر من‬

:Diaphragm 1
1. MTC mean: minimum toxic concentration
2. MTC means
a- Maximum toxic conc.
b- Maximum safe conc.
 2_MEC mean : minimum effective concentration
3-Cmax stands for:-
a-the maximum conc that drug conc reach
:Tmax stands for- 4
a- time at which plasma concentration reach
maximum

:In high therapeutic index- 5

b- a-more toxicity
c- b-no side effects

the drug conc above MTC indicate for- 6

a-toxicity
b-side effect

drug below MEC-7

a-ineffective
b-toxic

8-All of the following are non-competitive acetyl cholinesterase inhibitors,

except:
1- Donepezil
2- Rivastigmine
3- Galantamine (reversible and competitive ache inhibitor)
4- Tacrine

9_Mepredine not suitable for long time because???

1-cardiotoxicity
2-neurotoxicity (elderly) TRUE
3-nephrotoxicity

10-case about patient recently widowed, is suffering from severe

depression, is taking imipramine(TCA) block the reuptake of :
1- serotonin
2- norepinephrine
3- serotonin and norepinephrine TRUE
4- dopamine

11-same case about the widow

TCA metabolized by:
a-CYP 450
b-amine hydroxlase
 c-alcohol dehydrogenase

12_Same case about the widow

TCA block all of the following receptors except:
1- Histaminic receptors
2- Alpha adrenergic receptors
3- Beta adrenergic receptors True
4- Muscarinic receptors (cholinergic)
13_Same case about the widow:
TCA used in all of the following except:
1- Panic disorders
2- Schizophrenia true
3- Migraine
4- Neuropathic pain

14_Metabolic effects of BB include all of the following except:

1- Decreased glucagon release
2- Decreased glycogenolysis
3- Hypertriglyceridemia
4- Hyperglycemia true

15_Least effect for BB in :

1- Benign prostatic hyperplasia true
2- Myocardial infarction
3- Arrhythmia
4- Angina pectoris

16_All of the following decrease the effects of BB except:

1- Phenytoin
3- rifampin
4- Fluoxetine (increase effect of BB) TRUE

17_Female patients suffering from absence seizures, which of the following

is not indicated:
1- Ethosuximide
2- Lamotrigine
3- Diazepam
4- Carbamazepine TRUE

18_we are using all to treat absence seizure except:

a- phenytoin
b- valproic acid
c- ethosuximide
 d- lamotrigine

19-What is the drug of choice for status epilepticus :

1- Phenytoin true
2- Carbamazepine
3- Lamotrigine
4- Valproate

20_ All of the following anti-epileptic drugs are avoided in pregnancy

except:
1- Phenytoin
2- Valproate
3- Diazepam
4- clonazepam true

21_Doctor wants to discontinue anti-epileptic drug for female patient,

which of the following guarantees low recurrence:
1- EEG
2- History of frequent seizures
3- Onset in childhood true
4- MRI

22_Anti cholinergic used for motion sickness :

-scopalamine

23_Patients develop tolerance against all of the following effects of

morphine except:
1- Respiratory depression
2- Euphoria
3- Analgesia
4- Pinpoint pupil (miosis) true

24_All used for Morphine dependence except :

a. Methadone
b. Codeine true
c. Clonidine
d. Buprenorphine

25_Case about patient suffering from severe skeletal muscle rigidity and is
diagnosed with myasthenia gravis, which of the following is NOT true:
1- Diagnosed by edrophonium
2- Glucocorticoids are not useful in this condition true
3- Autoimmune disease caused by antibodies against ACH receptors at motor
endplate

26_All of the following are used for treatment of acute mania except:
1- Lorazepam
2- Chlorpromazine true
3- Lithium
4- Valproate

27_Toxicity of morphine can be reversed by:

1- Naltraxone true

28-Which drug is not used in parkinson’s disease:

1- Chlorthalidone, true
2- Bromocriptine
3- Amantadine
4- Rasagiline
29_Which of the following is CI in Parkinson:
1- Haloperidol
30_Long case about Parkinson patient:
What is the effect of carbidopa on levodopa:
1- Decrease its metabolism in the CNS
2- Decrease its peripheral decarboxylation to dopamine true
31_What are the symptoms of parkinson:
1- Tremors and agitation
2- Inability to initiate voluntary movements
3- Abnormal posture and gait
Ans: all

32_Which of the following vitamins decreases the effects of levodopa when

taken concomitantly :
1- Vit B6 puridoxine true
2- Vit B12
3- Vit B1
4- Vit B5

33_The decrease in the effect of levodopa occurs within:

11- After 5 years
2- After 3 years
3- After 2 years
4- From the 3rd to the 5th year true
34_Pilocarpine is used in all of the following except:
1- In narrow angle glaucoma
2- Alternatively with mydriatics to separate the iris
3- In closed angle glaucoma
4- Standard one for open glaucoma true
35_phenytoin side effect ,all except
a) gingival hyperplasia
b) nystagmus
c) nephrotoxicity true
36_Which of the following is ultra-short barbiturates:
Penobarbital (long action)
Thiopental true

37_Regarding Fluxetine :
a. half life is 50 hrs
b. have a metabolite as active as the parentdrug
c. used in bulimia nervosa
d.undergo first pass effect
answer... ALL

38_Which of the following used to make mydriasis in

checking refractive errors?
Atropine
Tropicamide true

38_case scenario about female patient have GOUT was weak & dizzy &
fatigue and another problems like she can’t raise her hand and having some
blood disorders like agrnaulocytosis and leucopenia and type of anemia
which anti gout are probably to cause this Side effects :
a- allopurinol
b- colchicines true

39_the qs about pharyngitis, the patient was penicillin allergic but the
organism is penicillin sensitive
A. Penicillin
B. Cephalosporin
C. Azithromycin true
D. Tetracycline

40-Which one of tetracyclines is suitable for renal failure pt ( it was in a

case ) :
a. Doxycycline
b. Minocycline
c. Tetracycline
41_which of the following is not fungus:-
a-mushroom
b-E.coli true

42_Bacteria move by :-flagella

43_ mitochondrial toxicity,, ANTIVIRAL used:
a-lamivudine
b-amatidine
c-zidovudine true
44_antiviral used in Parkinson :- amantadine
45_antiviral used for influenza and , Parkinson: ( came twice )
a-amantidine true
b-lamuvidine
c-zidovudine

46-used for HIV&HIB :- Lamivudine

47_In AIDS the CD4 less than:-

a-200 true
b-400
c-500
d-600

48-CD4 bind to which antigen in the HIV positive Pt:-

a-T lymphocyte true
b-B lymphocyte
49_case scenario about patient HIV and have low fever and lung diffuse and
ask which negative myco bacterium like to cause this infection :
Mycobacterium avium complex true

50_TB. medication ,INH,PYZ,RMP ,which is the SE. of INH ( came as a case ) :

answer... peripheral neuropathy

51_Which is not true about immune reconstitution inflammatory syndrom :

1) corticosteroids and anti - inflammatory drugs don’t shorten
inflammation action . true
2) The action of antiviral start when virus load is high .
3) The pt start respond to treatment when CD4 is high

52_Pt in the ICU for 3 days which antacid is used :-

a-PPIs

53-drug used in IBD(Inflammatory bowel disease) remission:

infliximab -

54_charcoal act by which :-

a-adsorbant true
b-absorbant

55_SIADH(Syndrome of inappropriate antidiuretic hormone) cause all of the

following except:-
a-hyponatremia
b-hypernatremia true
c-water excess
d-Inadequate vasopressin production

?ml ampoule of 3% drug how many ml required to give 150mg dose 56.10
a-3ml
b-5ml true
c-7ml
d-9ml

alcohol is to be diluted with purified water, how many parts of 50% ._57
?.purified water (0% alchohol) to prepare 20% preparation
a- 30parts water + 20 parts 50% alchohol

: Dose for patient is 75mg, how ml needed from 125mg/5ml solution . 58

a. 5 ml
b. 3 ml true
c. 15 ml

: How many gram of 5% ointment will be prepared from 2 gm . 59

?---answer.. (5%= 5gm ----100 ,,2gm
gm 40= 100/5*2

: How many gram will be in 250 ml of 5% solution . 60

answer.. 5% = 5gm ---100ml
250ml--------??
gm 12.5= 100/ 5* 250 =

: If dose of drug is 0.2 ml, How many dose will be in 15ml ._61
answer.. 15ml /0.2 ml =75 doses

:Advantages of IV route over oral route ._62

 1- safe and convenient, rapid onset, dose can be titrated, can be
used in ER
2- safe and convenient, can be used in ER
3- rapid onset, dose can be titrated, can be used in ER true
4- rapid onset, can be used in ER

:Foam in pharmacy found as spray is used as _63

1- Burn dressing and topical but not for rectal administration
2- Topical and rectal but not for burns
3- Topical, rectal and for burn dressing true
4- Topical only

-:which is true about dry gum emulsion - 64

a-ratio 4:2:1 true
b-water gum and oil are added together and triturated slowly
c-oil and gum are triturated and water added slowly.(water add at once
not slowly in dry gum emulsion)

:emulsion inversion .65

a-conversion of W/O emulsion to O/w emulsion and vice versa true

:Conductivity in emulsion, the dispersed phase for such emulsion is .66

a-Aqueous
b_Non aqueous true
c_Aqueous and non aqueous
-:velocity in dispersed phase affected by . 67
a-particle size
b-particle homogeneity
c-elecrtic charge
d-all

Conductivity test – Dilution test – Dye test used for which dosage . 68
: form
.a. Susp
b. Emulsion true
c. Foam
d. Gel

:Particle size affects .69

1- Suspend ability
2- Penetrability
3- Dissolution rate
 4- Dose to dose uniformity
5- Uniformity of tablet
6- All of the above true

_alprazolam (CDA) must store in: 70 ®‫آ‬Xanax .71

a. Steel cupboard well closed true
b. Cupboard opened by 2 person

yr old diabetic pt on oral hypoglycemica and suffering from 70 .-71

hypertension ; Which of the following antihypertensive drugs is not
: recommended
losartan -1
enalapril -2
Hydrochlorothiazide -3
Atenolol true -4

patient with hypertension put on antihypertensive drug, after few ._72

months developed heart failure manifested as reduction in heart rate
:and contraction, which antihypertensive drug patient put on
a. Lisinopril
b. verpamil true
c. prozosin
d. Thiazide diuretic

timolol is contraindicated in all the following except ._73

A.HTN true
b. Congestive Heart failure
c- Bronchial asthma

Beta blocker use in all except: Bronchial asthma _74

:prinzmetal angina ._75

a-sudden spasm
b-sudden spasm with atherosclerosis
c-sudden spasm with atherosclerosis and not responsive to CCBs and
nitroglycerin
d- sudden spasm ,with atherosclerosis, and respond to CCBs and
nitroglycerin true

??which of the following not used in prinzmetal angina ._76

atenolol true
nifedipine
nitroglycerin
dilitazem

years old Male patient , he is a smoker and he is taking an .77-78

antiarrhythmic medications , which of the following drugs should be
: avoided
A. Digoxin
B. Verapamil
C. Amiodrone true
D. lidocaine

Patient with arrhythmia discharged from the hospital which - .78

medication used to control his condition :-verapamil

:Common side effects of arrhythmic drug . 79

torsade de pointe

: CASE About Arrhythmia ( statements ) ._80

a-most cause of recurrent arrhythmia due to reentry
b-Most Of them is Calcium and sodium blocker
c-SA node is the pace maker ( something like that )
d.anti-arrythmic safer than operation
ans a&b&c
if except you will choice d

Patient with arrhythmia given medication that decrease the velocity ._81
: and force of contractility which one of this drugs
a. Verapamil true
b. enalapril

:Mechanism of action of digitalis all true except .82

a - increase contractility
b- decrease vascular resistance true
c- have modify effect on autonomic nervous system
d- maintain ventricular rate in atrial fibrillation

Case Patient with glaucoma and blood pressure 220/110 and . _83
-: hypertensive crisis and ask which to avoid
a-nicardipine
b-fenoldopam true
c-Na nitroprusside
d-labetalol
patient diagnosed with Hyperlipidemia and decreased HDL , what is ._84
? the drug useful in his condition
A) Niacin true
B) Clofibrate
C) Cholestyramine
D) Rousavastatin
CI of loop diuretic except:- renal impairment ._85

Thiazide diuretic doesn’t cause .86

hypokalemia .1
hypokalemia .2
Hypocalcemia true .3
Hyponatremia .4

All are route of administration of nitroglycerin except :-oral .87

:The role of B-blocker in MI is all of the following except _88

a-Decrease mortality and morbidity
b- decrease infract size
c- Increase O2 demand true

:The cough in ACE inhibitors((((: EXCEPT)))) _89

A. Accumulation of bradykinin
B. In women more than men
C. Appears in 6 months
D. Dose related

which one must be labeled and separated : epinephrine . 90

case about a child had hypersentivity reaction to bee sting : . __91

epinephrine

antiglacucoma means : drug that decreses IOP ._92

:graph : how much time it will stay in body _93

h 24
how much conc at time 12 : 5ng/mL _94
how much t max : 3 h ._95

Primaquine is contraindicated in all of the _96

:following except
 ‫‪SLE,RA -1‬‬
‫‪G6PD deficiency -2‬‬
‫‪Lactating female -3‬‬
‫‪Pregnancy -4‬‬
‫‪Ipratropium approved for:Maintaining COPD _97‬‬

‫‪atropine least S.E : - decrease gastric secretion ._98‬‬

‫دي االسئلة الي افتكرتها االمتحان‪ 100‬سوال في ساعتين‬

‫خليك قوي واوصل لحلمك‬

‫‪DR_ Eman Hassan‬‬

‫التنسونا من صالح دعائكم بالتوفيق للجميع‬

‫‪GOOD LUCK‬‬

‫‪25/5/2019‬‬
‫السالم عليكم ورحمة الله تعالي وبركاته ‪ -----------‬هذي اسئلة امتحان يوم‬
‫‪2019/5/25‬كانت مكررة من امتحان‪2017/2/7 0000‬نعتزر عن طريقة الكتابة‬
‫المختصرة بس عشان نلحق نكتبها قبلي ما ننساها كتبنها لكم باختصار شديد‬
‫(ياريت تراجعوها بالمقارنة مع امتحان )‪2017/7/2‬‬
‫نصيحة ‪ :‬قبل كل شي الزم تغطو جميع االمتحانات من ‪2015‬الي ‪2019‬الن‬
‫االمتحان لمن يتكرر بتكرر كامل فالبد من تغطية كل االمتحانات بشكل دقيق الن‬
‫صيغة‬
‫السؤال بتكون متغيرة شوية في االمتحان بس حتقدرو تتزكروها بالمزاكره الجيده‬
‫والتركيز الكل بينجح باذن الله تعالي‬

‫‪Aluminum hydroxide side effect………..constipation‬‬

‫‪2- Methylphenidate in AUE………….narcotic‬‬
‫‪3- Morphine like dependent………diacetylmorphine‬‬
‫‪4- Erythromycin …….short half life‬‬
‫‪5- Salbutamol over dose except …..constipation‬‬
‫‪6- Atropine side effect………..tachycardia‬‬
‫‪7- Digoxin toxicity……………….vomiting‬‬
8- Community acquired pneumonia…………..Influenza ,mycoplasma
pneumonia
9- Levothyroxine…………age
10- Levothyroxine……………except taken on full stomach
11- Levothyroxine …………….increase energy
12- Myopathy not side effect of……………..cholestyramine
13- 3pharmacist and no of assistant
14- Generalized tonic colonic DOC……………….Phenytoin
15- Sensitivity to dog………………..cetirizine
Propranolol in thyroid…………reduce
16-
thyroid symptoms and
inhibit conversion of T4,T3

17- Atenolol SE……………..fatigue

18- Amoxicillin SE……………Thrush
Metformin with DM type 2
19-
relevant………………obesity and
renal insufficiency

20- Corn ………………too much pressure

21- Aspartame not use in…………….Phenylketonuria
22- Stilbeglibtine…………….peptidase dipeptide inhibitor
23- Lipitor………………………IIa,IIb
24- Oral anti influenza……………………oseltamivir
25- Dose of ACYCLOVIR in zoster…………………5time
26- Suspension not use………………Iv
27- Clarithromycin…………shack well before use
28- Mupirocin ……………….dermatitis
29- Impetigo……………staph.aures
30- Broken ampule of morphine…………….incidence report
31- Pseudomembranous colitis………….clindamycin
32- Pseudomembranous colitis……..cefuroxime
33- B-lactamase resistance………………..cefipime
34- Oxymetazoline……………..increase heart rate
35- Allergic rhinitis………………..beclomethasone
36- Diphenhydramine ………..not use in morning sickness
37- Except open window to …………….allergic rhinitis
38- Hydrochlorothiazide MOA……………
39- Ephedrine……………not use with MAOI
40- Dry cough………enalopril
41- Inhibition at first dose…………..enalopril
42- High Vd mean……………bind to tissue
43- Low bioavailability………………..need high dose
44- Acetominphine over dose……………..ALT
45- Opioid agonist……………………….tramadol
46- To prevent reinfection…………………..aspirin
47- Cefuroxime stat………………given without delay
48- Poly dyspepsia, poly phagia………………..DM
49- Vaccine yearly………………..influenza
50- Vaccine……….elderly
51- Beclomethasone…………… (tow choice)
hold breath 10sec….,,,rinse mouth
52- Levothyroxine…….why your visit doctor
Constipation……….call the doctor to
53-
know cause of
Constipation

54- Iron decease absorption of……………moxifloxacillin

55- Doxapram…………………hypercapnia
56- Not need horizontal…………….doxorubicin
57- Alprazolam…………….steel cupboard when locked
58- Alprazolam…………….short acting
59- Antipsychotic except………..thiazide
60- Fiber……………..all the above
61- Drug need renal adjustment………..pyz,RIF
62- Statin………….except take tab at breakfast
63- Hyperparathyroidism………….dihydrotachysterol
64- Hypercholestrol……………….fenofibrate
2inhaler in home and one at school……advise for
65-
asthmatic
pt.

66- Lanatoprost…………….mechanism of action

67- Not SE of cocaine…………..peripheral vasodilator
68- Bactrocin nasal spray………………………staph.aureos
69- Potent corticosteroid…………clobetasol
MOA OF EPINEPHRINE……………………increase
70-
blood
Pressure

71- Not use in dandruff………………….permethrin

72- Metoclopramide………………………skip the missing dose
73- Phenytoin similar to………………lidocaine
74- Pt. with peptic ulcer……………..lasoprazole
75- To reduce UN movement………………..vancroium
76- Selective fibriolytic………………………..alteplase
77- Narrow therapeutic index……………….all (heparin
,alprazolam, warfarin)
78- Paraffin not use of pneumonia………………
79- Gentamicin not toxic………….plasma conc. less than 2mg
80- Used in neuropathic pain more than
norceptive………..nortriptylline
81- Saline flush……………insert into circulation
Calculations were more in our exam, about 15 Question (please read
all calculation on group files)
the question was direct in our exam:

We recall 13 out of 15 calculations:

1. ????????????????Dopamine…………360
2. ???????????Morphine……………120
3. ???????………………….. the answer was Less than 1 %
4. ???????????6*7…………………………42 day
5. ???????????????Zinc …………………………392
6. ????????????????Infusion rate…………………. 30
7. ??????????????Ranitidine…………….. 2.5
8. ??????????????100ml ,,,10ml of 2%....................20
9. ???????176 Ib …………….
10.????????T/l2 of 99%...............13.5hr
11.??????????????Amoxicillin………………..100mg
12.???????????????Metoprenalol…………………0.6
13.???????????????0.25%w/W………………..

June-22-2019

1-which of the fallowing considered as Narcotic according to UAE regulations:

A.methylphenidate 5mg tab

B.bupernorphin 500 inj

C.buprenorphen 200 mcg tab

D.nabluphine

2-in 24 hrs pharmacy we need :

3 pharmacists and unlimited number of assistants

3- Mupirocin used in:

Skin infection, like impetigo = due to SA , Strep Pyogenes

contact dermatitis

4- To reduce peptic ulcer use:

Lansoprazole

ibuprofen

5-Patient using dopamine infusion with 2.5mcg/kg/min, pt. wt 80kg How many ml of doamine
pt will consume if dopamine ampoule con 0.8/1ml with in 24 hours. 360ml

6- A physician wants to switch a terminally-ill patient from slow release morphine sulphate
tablets, 15 mg twice daily, to a liquid morphine sulphate dosage form because the patient has
difficulty in swallowing tablets. If a morphine sulphate solution containing 5 mg per mL is
prescribed q4h, what volume should be dispensed for a 20 day supply to provide the same pain
relief as the tablet regimen?

a. 20 mL

b. 60 mL

c. 80 mL
d. 100 mL

e. 120 mL

7- A drug with t1/2 is 3 hr, after how many of this drugs will remain in the body after 24 hr?

100

87

12.5

6.125

less than 1✔

8- The dose of the drug is 5mg/kg/day in divided doses, how many mg of this drug that the
patient will take it twice daily? patient weight is 176 Ib

a. 200 mg

b. 400 mg

c. 50mg

9- take 220 mg anh znso4 to receive amount of elemental zn , how many mg of

znso4 (7H2o) have to take ? ( m wt zn 65 , mwt znso4 161, H2o 18 ) . 329

10- pt use augmentine 600mg contain 42,9 mg potassium ,pt dose is 90 mg\kg

how much k per this dose ? 100

11- what is the infusion rate, of drug in blood is 10mcg/ml , clearance rate is 0.25/hr and
vd is 12L? 30

12- 100 ml sol contains 10 ml 2% drug what is the conc of the final drug ? 2mg/ml

13-. metaprotrenol salt 15 mg/ 1 ml , m.wt =520, base= 211….how much %strength of base
in the soln? 0.6 %

14- Which is true statement about Alprazolam:

a. Short-acting anyxiotylic BDZ

b. Doesn’t need dose adjustment in elderly

c. Doesn’t have interactions with drugs

d. Dose is 0.25-0.5 microgram 3times

15- Which drug doesn’t cause myopathy:

a. Simvastatin

b. Gemfibrozil

c. Fluvastatin

d. Cholestyramine

16. The best advice for patient taking theophylline SR 300mg is :

a. Don’t crush the tablet, swallow whole.

17. Corns are associated with:

a. High pressure from shoes

18- Vertical laminar flow hood is used in:

a. Aminophylline

b. Nitroglycerine

c. Doxorubicin

d. Penicillin

19- . Auxiliary label for clarithromycin suspension

a. Shake well before use

20- Cocaine toxicity includes the following except

euphoria, wide pupil, tachycardia, peripheral vasodilation

21-Not used with ephedrine: MAOI

22- PQ is a 75 year old patient who has just been diagnosed with hypothyroidism. Her past
medical history is significant for congestive heart failure, type 2 diabetes mellitus,
osteoporosis and chronic stable angina, all of which are well-controlled. Her medications
include:

Metoprolol 25 mg bid

Calcium carbonate 1250 mg bid

Vitamin D 1000 IU daily

Glyburide 2.5 mg bid

Enalapril 10 mg bid

Furosemide 40 mg daily

Nitroglycerin SL spray prn

PQ should be started on a low dose of levothyroxine because of her:

a. age.

b. gender.

c. diabetes.

d. metoprolol use.

e. nitroglycerin use.

23- Appropriate counselling and follow-up for PQ with initiation of levothyroxine

includes all of the following, EXCEPT:

a. separate the levothyroxine dose from calcium tablets by several hours.

b. take levothyroxine on a full stomach for greater absorption.

c. improved control of thyroid levels may also improve her glycemic control.

d. physician follow-up is needed in 6-8 weeks to have her thyroid function

tests repeated.

e. closer monitoring of her angina should be done during dosage titration of

levothyroxine.

24- Which of the following parameters is the most appropriate for PQ's self-evaluation of
the effectiveness of levothyroxine therapy?

a. Increased energy

b. Weight loss

c. Improved vision

d. Less frequent angina

e. Less frequent urination

25- As an antiarythmic drug lidocaine is most similar in action to

Phenytoin
26-Macrolide with the shortest half life :

Erythromycin

Azithromycin

Clarithromycin

27-Medication is preferred to be used in neuropathic pain rather than nociptive pain:

a. Nortryptillin
b. Ibuprufen
c. Tramadol

28-Classified as opioid agonist:

Tramadol

29- Symptoms Of Digoxin Toxicity :

a. Increase heart rate
b.Vomiting
c. Drowiness

30-Not considered as an antidepressant :

Chlorothiazide

Escitalopram

paroxetine

31- the one causes rebound congestion after long time using:
Pseudoephedrine tablet
oxymetazoline
32- ahmad is allergic to dogs and cats,he will travel to his friend who has a dog ,he csme to
the pharmacy and talled u that he is also hyperthyrodism. What OTC can he take:
a. Psuedoephidrine
b. clarinase (loratidine &pseudoephidrine)
c.cetrizine before the visit

33-chronic sinusitis inflamation can be treated by:

Oral pseudoephedrine
a. Nasal oxymetazoline spray
b. *nasal beclomethasone spray

34-act as enzyme inhibitor in the first dose: enalapril

35- which have narrow theraputic index :

a. Warfarn ,vancomycin, alprazolam
b. Heparin ,alprazolam ,warfarin
c. *Vancomycin, heparin. Warfarin

d.all of the above

36- continues comming patient to a pharmacy with a tenolol 25 prescription , but this time
the Dr hand writing is not clear . What shall u do?
a. Ask the patient if the Dr has changed the dose
b. give him the usual dose that he takes ,25

c-call the doctor and confirm the dose

37-Antibiotic that resistant to B-lactamas producing organism

cefepime
Imepinem

38 -Elderyl patient , yearly vaccine>?

A*Influenza Vac
39- Which of the following liver enzyme is the first to be elevated in a case of an
acetaminophen overdose ?
ALT

AST

40- Metformine prevalent pt. factors when considered as monotherapy include

a* Obesity
b* Renal dysfunction
c* Obesity and renal dysfunction
d-Hypothyroidism

41Thrush caused by ……

Amoxicillin

42—Oral Salbutamol overdose all EXPT……

Constipation

43—High volume of distribution mean

a* High bound to tissue

44- Clarithromycin suspension advice ??

a* Shake well before use

45-Theophyline advice:

Don’t chew or crush

46-patient suffer fromcold sore and you give him acyclovir how many times he should
apply
1 time
4 times

5 times

47-one lady patiant with levothyroxin Rx >> you want to be sure that she understands why
she is taking her medicine what is the most appropriate question to ask her

1. did you remove your thyroid

2. did your doctor tell you that you have hypothyrodism
3. Why did you see your doctor?

48-If the bioavailability of a drug is low, this means:

-low gastric absorption
-low metabolism
-low renal excretion
-high doses must be taken

49- Old man takes these medications, cefuroxime 500mg and celecoxib 200mg, he is
suffering from fresh bloody stools and vomiting, this is like because of: -

Antibiotic associated pseudomembranous colitis

Celecoxib associated pseudomembranous colitis

50- DOC for generalized tonic- clinic seizures : (Make sure)

Ethosuxamide

Phenytoin

Topiramate

clonazepam

51-DS is a 27 year old male who comes to the pharmacy seeking advice because, for the
past 24 hours, he has experienced abdominal cramping, mild fever and frequent, loose
stools with some blood loss. DS thinks it may be related to the antibiotic he has been taking
for a dental abcess. Current medications include: clindamycin 150 mg QID x10 days, started
8 days ago, and losartan 25 mg daily for hypertension, started 3 months ago. The most
appropriate pharmacist response is that these symptoms:
a. are expected, transient side-effects of clindamycin; treat symptoms and continue
medications.
b. may indicate an interaction between clindamycin and losartan; pharmacist call to dentist
is warranted.
c. may indicate clindamycin-related pseudomembranous colitis; seek immediate medical
attention.✔

d. may indicate losartan-related pseudomembranous colitis; seek immediate medical

attention.

52-Treatment of Hypoparathyrodism:

A. Dihydrotachysterol
B. Levothyroxine
C. Levothyroxine and Dihydrotachysterol
D. Levothyroxine and Propythiouracil
53-What is the effect of propranolol on patients with hyperthyrodism

Reduce the heart rate to less than 90 and reduce thyrotoxicosis symptoms

Prevent the conversion of t4 to t3 and reduce thyrotoxicosis symptoms

Reduce the heart rate to less than 90 and prevent thyroid storm

Prevent the conversion of t4 to t3 and prevent thyroid storm

54-Symptoms of Digoxin toxicity :

A. Increased heart rate

B. Decreased heart rate
C. Vomiting
D. Headache (I am not sure)
55- The vasopressor effect of epinephrine on the body:
A. Increased blood pressure
B. Decreased blood pressure
C. Removal of fluid from the body
D. Relaxation of smooth muscles
56-The effect of anticholinergics (atropine-like) on older patients

A. Drowsiness
B. Can’t remember the rest
57- Give cefuroxime 750mg IM stat.:

a- give recommended dose with out a delay

58- something about latanoprost “ sorry we couldn’t remember “

59- Question about fenofibrate

a. Used to decrease total cholesterol in the body

60- Patiant diagnosed with pneumonia microorganism, he was healthy before he catches
the disease. Which antibiotic is suitable?

a. Pathogen is mycoplasma-and treatment is (macrolide)

b. Pathogen is pseudomonas-and treatment is levofloxacin
c. Pathogen is mycoplasma-and treatment is levofloxacin
d. Pathogen is pseudomonas-and treatment is clarithromycin (macrolide)

61- Broken morphine Ampoule:

A- Report it in incidence report

B- Discard it in the rubbish

C- Put it in special bag and label it

D- Report it in the log narcotic file

62-. JG has been taking metoclopramide 20 mg, po q6h for the past 3 days as part of

her chemotherapy regimen. She normally takes 4 doses daily, with each meal and at

bedtime. This morning, she forgot to take her morning dose before leaving home for
a hospital check-up. When she arrives at the clinic, she asks the pharmacist what

she should do about her missed dose, as she expects to be home again around 11:00

am. The pharmacist should advise JG to:

a. take the missed dose immediately when she gets home and continue as

scheduled.

b. take two doses at lunchtime to make up for the missed dose.

c. skip the missed dose and take the next scheduled dose at lunchtime.

d. skip today’s medication and resume her normal schedule tomorrow.

e. space 4 doses into the remaining hours between when JG gets home and her

bedtime.

63- …. Morphine

a. Diacetylmorphine
That’s what we could remember…

The exam’s questions were recalled from previous papers .. please double check the
answers

‫ نسألكم صالح الدعاء‬All the best

24/7/2019- Version 1

1. Female taking UTI medication, after few days she developed

rashes and red spots on hands, face, (they mean to say exposed
areas) what medication she's on? They attached a hand that
shows red spots with the question SE of:
a) ciprofloxacin
b) amoxicillin
ans: a (if we consider it photosensitivity)
2. Antibiotic that can resist B lactamase producing bacteria:
a) cefopodoxime
b) cepoperazone
c) Azithromycin
d) cefazoline
ans:c
3. DOC for meningitis:
a) Ceftriaxone
b) Tetracycline
c) Chloramphenicol
ans: a
4. least used for beta lactamase producing bacteria
a) amoxicillin +clavulinic acid
b) Dicloxacillin
c) Erythromycin
d) Doxycyclin
ans: b & c (pls ckeck which is correct)
5. Doc of pregnant woman with UTI: it was a case
A. Cefuroxime
b. cephalexin
ans: b
6.pt was found to have an infection with gram +ve and -ve, which
drug to use? We have to choose a broad spectrum antibiotic
Amoxicillin
7. The use of broad spectrum/ long term use of antibiotic can
cause which infection
a) heleicobacter pylori
b) E.coli
c) shigella
d) Clostridium difficle
ans: d
8. Antibiotic cause ear problem (ototoxicity) needs audiometry:
amikacin
9. Valacyclovir benefit over acyclovir:
a) better bioavailability
b) better tolerance
c) less renal impairment
d) all of them
ans: a
10. Acyclovir is not effective in for which virus:
a) Herpes simplex
b) Epstein-barr virus
c) CMV e)herpes zoster
ans: c
11. What is the antiviral that’s the most suitable for HSV
encephalitis infection?
a) acyclovir
b) foscanet
ans: a
12. Mechanism of action of acyclovir:
a) DNA polymerase inhibitor.
b) RNA polymerase
c) transcriptase
ans: a
13. All decrease the effect of digoxin except:
a) captopril
b) cycloserine
c) azithromycin
d) cephalexin
ans: c
14. Digoxin cannot be used in which condition:
a) Complete Heart failure and atrial fibrillation.
b) Along with ACEI and diuretics
c) ventricular diastolic failure
d) ventricular systolic dysfunction
ans: c
15. Digoxin MOA is
Positive inotropic effect
16. Which is not used in prinzmetal angina:
a) Atenolol
b) Nifedipine
c) Nitroglycerin
d) Diltiazem
ans: b
17. Sulfasalazine should be given with which supplement:
Folic acid
18. Not for crohn's disease:
a) Adliximab
b) Infliximab
c) certolizumab
d) Ustikenumab or Golimumab (can't remember but both used)
e) Etanercept
ans: e
19. Treatment of mailgnant glioma:
a)methotrexate
b)dacarbazine
c)6-mercaptopurine
d)carmustine
ans: d
20. Patient on cyclophosphamide has developed hematuria due to
release of which substance:
a) phosphoramide mustard
b) Acrolein
c) Mensa
ans: b
21. Etoposide causes DNA damage through inhibition:
a) Topoisomerase I
b) Topoisomerase II
c) Topoisomerase III
d) Topoisomerase IIII
ans: b
22. Letrozole: (came as 4 statements and then in the choices
combinations of them for example: a only, a&b. b&d and so on
…)
a) mild androgenic SE
b) aromatase inhibitor
c) does not cause endometriosis (true as it treat endometriosis)
d) no need corticosteroid co administration ( Double check this
one)
ans: b,c,d
23. Maximum duration for the use of tamoxifen is:
a) 2 years
b) 5 years
c) 7 years
d) 10 years
ans: d
24. Patient was on cyclosporine and changes to tacrolimus)
Tacrolimus comparison with Cyclosporine , which answers are
true
a) more potent
b) less nephrotoxicity and neurotoxicity
c) longer duration
d) lower rejection rates
ans: ecxept b
25. Cyclosporine is more toxic in which route:
a) oral
b) IV
c) IM
d) SC
ans: b
26. Patient take DMARDs and after 2 weeks have eye problem
which drug cause that:
a) sulfalazine
b) hydroxyquine
ans: b
27.Enfuvirtide added to HIV patient regimen what true about it:
a. integrase inhibitor . Wrong as its fusion inhibitor
b. S.C
c. can used without reconstitution (false as its powder for
reconstitution)
d. low side effects (it was in all choices)
ans: b &d
28. Insulin that cannot be given as an IV:
a) Lispro (rapid acting)
b) Aspart (rapid acting)
c) Glulisine (rapid acting)
d) isophane
ans: d
29. All indications of diabetes except: (came as 4 statements and
then in the choices combinations of them for example : a only,
a&b. b&d and so on …)
a) Polyuria and unexplained weight loss
b) Random blood glucose of 200
c) Fasting blood glucose of 140
d) Blood glucose level of 200, 2 hours post oral glucose intake
ans: b
30. Which drug has least effect of hypoglycemia? (if acrabose is
there choose it)
a) metformin
b) glibenclamide
ans: a
31. Action of insulin except:
a) Decrease glucose production in liver
b) Decrease liver glucose uptake
c) Insert glucose in muscle and adipose tissue answer
ans: b
32. A child took peanut butter and he’s allergic to peanut; he
developed rashes and urticarial. What type of allergic reaction is
this?
a) Type 1
b) Type 2
c) Type 3
d) Type 4
ans: a
33. Side effect that most people who take B2 agonist may have:
a) Hypokalemia
b) Tremors
c) hypomagnesia
ans: b
34. Insulin secretion form:
a) B cell
b) Alpha cell
ans: a
35. A child suffered from acute asthma attack and diagnosed with
asthma which single treatment for long term use to prevent
exacerbations of asthma:
a) Salmeterol
b)Ipratrobuim
c)Salbutamol
d) budesonide
ans: d
36. Prostaglandin anti-glaucoma drug approved for eye lash
Hypotrichosis:
a) bimatoprost
b)latanoprost,
c)travoprost
d)Ilosopt
ans: a
37. Which anti TB drug cause urine discoloration (reddish
coulour):
Rifampicin
38. Topical treatment for hair loss(baldness) for 25 years old
male:
Minoxidil
39. Injectable anticoagulant mechanism of action:
a) potentiate anti thrombin III effect
b) antiplatelet aggregation
c) inhibit coagulation factors synthesis
ans: a
40. NOT FIRST LINE treatment for TB:
a) streptomycin
b) INH
c) Rifampicin
d) pyrazinamide
ans: a
41. A drug that has high risk for thrombosis and MI
celecoxib
42. DOC for status epilepsy:
a) clonazepam
b) diazepam
c) Phenobarbital
ans: b
43.DOC for pregnant hypertension:
a) methyldopa
b) Hydralazine
ans: a
44. Patient taking ACEl which antacid should not be used?
a) Calcium carbonate
b) Magnesium
c) Aluminum
d) Potassium bicarbonate
ans: d due to high risk of hyperkalemia
45. pro-kinetic drug has anti emetic effect:
a) domepridone
b) Cisapride
ans: a
46. Picture of nail with thick texture and brown discoloration,
Nail fungal infection DOC:
a) Fluconazole
b) Terbinafine
c) Griseofulvin
ans: b
47. Contraceptive contraindicated with lactating mother:
a) Progestin alone
b) combination
c) copper T (loop)
d) condoms
ans: b
48. Female is menopause, she experiences hot flushes, developed
spinal osteoporosis which to use?
a) Alendronate
b) Estrogen and progesterone
c) progestin
ans: a
49. All are factors affect cerebro-spinal fluid (CSF) penetration
Except:
a) lipid solubility
b) water solubility
c) Molecular weight
d) Plasma protein binding
ans: b
50. IBS (irritable bowel syndrome) symptoms and the physician
advised the patient to eliminate dairy products from diet for
about 3 months, which symptom the patient have?
a) chronic constipation
b) chronic diarrhea
c) alternatively constipation and diarrhea
ans: a
note: diary products cause constipation
51. Which is not given for constipation?
a) Lactulose
b) Loperamide
c) Na-Pico sulfate
d) Docusate sodium
ans: b
52. All of the following cause constipation except:
a) Bisacodyl
b) Morphine
c) Calcium
d) ACEI
ans: a
53. A patient suffers from esophagus reflex , which additional
symptoms if happened the patient should be referred to
cardiologist?
a) mild pain in arms
b) pain in central abdominal
c) pain that spread to jaws, neck, shoulders and arms
d) pain in illu fosse "something like this"
ans: c
54. Patient has a problem in bowel emptying, he develops pain
while passing stool, Which is the least likely condition to cause
this constipation?
a) Bowel obstruction
b) IBD
c) Carcinoma
d) hyperthyroidism
ans: d (hyperthyroidism cause bowel movements and diarrhea )
55. Pharmacist monitoring of drug dispensing and refill will give
an idea about:
a) Drug utilization
b) Drug disposal
c) Drug adherence
ans: a
56. What’s the type of study that’s MOST reliable?
a) Cohort randomized trials
b) Case study
c) Case report
d) case series
ans: a
57. What’s the type of study that’s LEAST reliable? Memorize
types of studies please
- Cohort randomized
- Case study
- Case report
- Case scenario
Ans:c
58. Manufacturer recall of medication from pharmacy is called:
a) Voluntary call
b) Immediate recall
c) involuntary call
ans: a
59. patient with ED (erectile dysfunction) and take Sildenafil
which one is absolute CI with sildenafil:
isosorbide dinitrate
60. A physician wants to switch a terminally-ill patient from slow
release morphine sulphate tablets, 15 mg twice daily, to a liquid
morphine sulphate dosage form because the patient has difficulty
in swallowing tablets. If a morphine sulphate solution containing
5 mg per mL is prescribed q4h, what volume should be dispensed
for a 20 day supply to provide the same pain relief as the tablet
regimen?
a) 20 ml
b)40 ml
c)60 ml
d)120 ml
ans: d
61. Case of female who has panic when she has to speak to
audience. Treatment of acute panic attack:
a) benzodiazepines
b) TCAs
c) antipsychotics
D)SSRIs
e) Buspirone
ans: a
62. True about SSRIs:
a. most effective in chronic anxiety disorders
b. give effect 1-4 weeks.
c. can't be first line for anxiety disorders
ans: a
note: effect within 6-8weeks
63. Benzodiazepines EXCEPT:
a) Muscle relaxants
b) Anxiolytics
c) Antrograde amnesia
d) antipsychotics
ans: d
64. DOC with b blockers in aortic dissection
a)minoxidil
b)hydralazine
c)diazoxide
d)sodium nitroprusside
ans: d
65. Enalapril not beneficial effect:
a. decrease inotropic effect
b. decrease renin release
c. decrease angiotensin effect
d. V.D by brady kinnin accumulation
ans: d
66. Not enalapril SE:
a) Dry cough
b) Angioedema
c) hypokalemia
d) postural hypotension
ans: c
67. ACEI can increase level of
? a) sodium
b) potassium
c) calcium
d) magnesium
ans: b
68. Hypertension emergency which one to use:
a) sodium nitroprusside
b) Clonidine
C) Captopril
ans: a
69. Which of the following causes tachycardia:
a)Propranolol
b)verapamil
c)diltiazem
d)isosorbide dinitrate
ans: d
70. When giving ethambutol for a long duration, continuous
follow-up/check-up is necessary because of this condition:
a) Renal failure
b) Liver dysfunction
c) vision problem ( ocular toxicity )
ans: c
71. What infection the previous antibiotic cause:
a. heleicobacter pylori
b. E.coli
c. shigella
d. Clostridium difficle
ans: d
72. Grey color baby due to antibiotic:
a. chloramphenicol
73. What is the drug of choice of HSV infection?
a. acyclovir
74. true about Paracetamol:
a. small risk of Reyes syndrome (wrong as it has no risk, the small
risk is for aspirin)
b. anti-inflammatory (it has very weak or no anti-inflammatory
action)
c. inhibit PG in CNS
d. no platelet action (aspirin has antiplatelet action)
answer: c & d
75. Aspirin difference from other NSAIDS:
a. has cardio beneficial effect
b. irreversible COX inhibitor
c. can't stop arthritis progression
ans: a & b
76. Aspirin overdose symptoms are all of the following except:
a. Hypothermia
b. Metabolic acidosis
c. Respiratory depression
d. convulsions
ans:a
77. Patient with gout history present to ER with gouty attack,
which NSAID is contraindicated:
a. Aspirin.
b. sulindac
c. Ibuprofen
ans: a
78.When patient take prophylaxis therapy for gout:
a. more than One attack per year
b. Association with Kidney stones
c. ureate excretion 500 mg
d. blood urea level 10mg/dl
Ans. B&D correct
79.NSAIDS contraindicated with sulfa sensitivity:
a. Celecoxib
b. Ibuprofen
c. naproxen
d. indomethacin
ans: a
80. Insulin type that's its reaction time is not effected by site of
administration?
a. Glargine (Lantus)
b. Isophane (Humuline)
answer: A
81. Sulfasalazine prevents the absorption of which element:
a. Folate
82. Used in motion sickness except:
a. Hyoscine (scopolamine)
b. Meclizine
c. Promethazine HCL
d.propamide
ans:
83. Which iron/ folate dose is questionable?
a. 120 mg for 20 kg child
b. 90 mg for 15 kg child
c. 21 mg for 7 kg infant
d. 30 mg for 6 kg infant
ans: d
84. case about patient has difficulty in breathing at the last 30
minute , his family is asthamatic and he has experienced
asthma ,what is used for decreasing difficuty
A.salbutamol
B.Albuterol
C terbutaline
D corticosteroid
Ans: b
85. which of the following drugs acts on T-lymphocyte blocking?
-adluximab
-etanercept
-alefacept
Ans: c
86. all can resist beta lactamase in bacterial except:
a. augmentin
b. erythromycin
c. Dicloxacillin
d. Doxycyclin
Answer: B (check please)
87. What is the medication that’s used in the treatment of
glaucoma, medication-related edema, heart-failure related edema?
Acetazolamide
88. Treatment for influenza A and B, cleaves sialic acid (or sth
like this)
One of the answers was Oseltamivir
89. Which of the following no need for antibiotic dose adjustment:
a) hypercholesterolemia
b) elderly patient
c) renal disease patient
d) AIDS
Ans. A
90. Cromolyn used in asthma to :
a. Decrease inflammation
b. Mast cell stabilizer(decrease mast cell degranulation)
ans: b
91: Selective cox 2
Celecoxib
92. Patient diagnosed with hodgkin lymphoma. Doctor decides to
stop him from dairy product. Which amino acid patient will
avoid:
Tyramine
93. patient with TB take more than one drug why??
To decrease the risk of developing drug-resistance
94. NSAID has CNS side effects:
a. celecoxib
b. sulindac
 c. nabumetone
d. mefenamic acid
ans: d
95.NSAID given for patent ductus arteriosus (PDA):
a) Indomethacin
b) Sulindac

sorryyy guys this much only I have remember

thank god & thankyou soo much my dear frds
best of luck

24/7/2019- Version 2

My exam(24-7-2019)5.Question was about a pt suffer from esophagus reflex , which

additional symptoms if happened pt should be transfer him to cardiologist?
a. mild pain in arms
b. pain in central abdominal
c. pain in arms , jaws and shoulders
d. pain in illu fosse "something like this" Λ
6.ACE can Increase level of ?
a. sodium
b. potassium
c. calcium
d. magnesium
7. A Kid took peanut butter and he’s allergic to peanut; he developed rashes and
urticaria. What type of allergic reaction is this?
a. Type 1
b. Type 2
c. Type 3
d. Type 4
8. Pharmacist monitoring of drug despising and refill will give an idea about:
a. Drug utilization
b. Drug disposal
9. What’s the type of study that’s MOST reliable?
a. Cohort randomized trials
b. Case study
c. Case report
d. case series
10- What’s the type of study that’s LEAST reliable?
a. Cohort randomized
b. Case study
c. Case report
d. Case series
11. Manufacturer recall of medication from pharmacy is called:
a. Voluntary call
b. Immediate recall
c. involuntary call
12. Which folate dose is questionable?
a. 120 mg for 20 kg child
b. 21 mg for 7 kg infant
c. 30 mg for 6 kg infant
13- A physician wants to switch a terminally-ill patient from slow release
morphine sulphate tablets, 15 mg twice daily, to a liquid morphine sulphate dosage
form because the patient has difficulty in swallowing tablets. If a morphine
sulphate solution containing 5 mg per mL is prescribed q4h, what volume should
be dispensed for a 20 day supply to provide the same pain relief as the tablet
regimen?
a. 120 Ml
14. topical treatment for hair loss(baldness) :
a. Minoxidil
15.treatment of mailgnant glioma (not malignant glaucoma):
a.methotrexate
b.dacarbazine
c.6-mercaptopurine
d.carmustine
16.amino acid contraindicated with procarbazine:
a.phenylalanine
b.tyramine
c.valine
d.leucine
17.pt suffer from acute asthmatic attack:
a.Salmeterol
b.Ipratrobuim
c.Albutarol 18. Patient on cyclophosphamid has developed hematuria due to
release of which :
a. phosphoramide mustard
b. Acrolein
c. Mensa
19. Etoposide causes DNA damage through inhibition:
a. Topoisomerase I
b. Topoisomerase II
c. Topoisomerase III
d. Topoisomerase IIII
20. Treatment of acute panic attack:
a. benzodiazepines
b. TCAs
c. antipsychotics
D.SSRIs
21. SSRIs:
a. Best For long term use
b. give effect 1-4 weeks.
c. can't be first line for anxiety disorders
22. Benzodiazepines not:
a. muscle relaxants
b. anxiolytics
c. retrograde amnesia
d. antipsychotics
23. DOC for status epilepsy:
a. clonazepam
b. diazepam
24.DOC with b blockers in aortic dissection
a.minoxidil
b.hydralazine
c.diazoxide
d.sodium nitroprusside
25. decrease effect of digoxine except :
a. captopril
b. cycloserine
c. azithromycin
d. cephalexin
26. Contraindicated in CHF :
a. hydrochlorothiazide
b. nefidipine (as it will cause reflex tachycardia worsening the case)
c. captopril
d. digoxin
27. Digoxin cannot be used in which condition:
a. Complete Heart failure and Atrial fibrillation.
b. Along with ACEI and diuretics
d. ventricular diastolic failure
e. ventricular systolic dysfunction (used)
28. Enalapril not beneficial effect:
a. decrease inotropic effect
b. decrease renin release
c. decrease angiotensin effect
d. V.D by brady kinnin accumulation
29. Case of using 4 drugs, which of them develop Dry cough:
Enalapril
30. Not enalapril SE:
a. Dry cough
b. Angioedema
c. hypokalemia
31. All are side effects of ACEI except:
a. Hypokalemia
b. Low level of potassium
c. dry cough
d. angioedema
32. Patient taking ACEl which antacid should not be used?
a. Calcium carbonate
d. Potassium bicarbonate due to high risk of hyperkalemia
33. Injectable anticoagulant mechanism of action:
A. potentiate anti thrombin3 effect… as injectable is heparin
b. antiplatelet aggregation
c. inhibit coagulation factors synthesis
34. DOC for pregnant hypertension:
a. methyl dopa
35. Hypertension emergency:
a. sodium nitroprusside
36- Which of the following causes tachycardia:
a.B blocker
b.verapamil
c.diltiazem
d.isosorbide dinitrate
37.patient with ED (erectile dysfunction) and take Sildenafil which CI with
sildenafil:
a. isosorbide dinitrate
38. Rash in exposed area (hands face & neck) SE of:
a. ciprofloxacin
40. DOC for meningitis:
1. Ceftriaxone
2. Tetracycline
3. Chloramphenicol
41. Type of penicillin that cannot be administered IV:
a. Penicillin G
b. Penicillin V
42. Doc of pregnant woman with UTI: it was a case
A. Cefuroxime
b. cephalaxin
43. What infection the previous antibiotic cause:
a. heleicobacter pylori
b. E.coli
c. shigella
d. Clostridium difficle
44. Which of the following no need for antibiotic dose adjustment:
a. hypercholesterolemia
b. elderly patient
c. renal disease patient
d. AIDS
45. Long case asking about Grey baby syndrome as a SE for by: chloramphenicol
In my exam there was cephalexin in choices
a. 47. Bacteria can resist this antibiotic by:
a. enzyme production
48. Antibiotic cause ear problem (ototoxicity) needs audiometry:
a. amikacin
49. NOT FIRST LINE treatment for TB:
a. sreptomycin
b. INH
c. Rifampicin
d. pyrazinamide
e. ethambutol
50. Which anti TB drug cause urine discoloration:
a. Rifampicin
51. When giving ethambutol for a long duration, continuous follow-up/check-up is
necessary because of this condition:
a. Renal failure
b. Liver dysfunction
c. vision problem ( ocular toxicity )
52.Enfuvirtide added to HIV patient regimen what true about it:
a. integrase inhibitor X . Wrong as its fusion inhibitor
In my exam there was Amikacin , Not
streptomycin
b. S.C
c. cant used without reconstitution
d. low side effects
53.Valacyclovir benefit over acyclovir:
a.more bioavailability( true its 55% but acyclovir is 20%)
b.more patient compliance (true as taken twice daily not 5 times like acyclovir)
c. can't remember
d. all of them
54. Acyclovir is not effective in which viral infection:
a. Herpes zoster
b. Epstein-barr virus
C.CMV
d. herpes zoster
55. What is the antiviral that’s the most suitable for HSV infection? a. acyclovir
56. Mechanism of action of acyclovir:
a. DNA polymerase inhibitor.
57. Picture of nail with thick texture and brown discoloration, Nail fungal infection
DOC:
a. Fluconazole
b. Terbinafine
c. Griseofulvin
58. Paracetamol: a. small risk of Reyes syndrome (wrong as it has noooo risk, the
small risk is for aspirin)
b. anti-inflammatory
c. inhibit PG in CNS
d. no platelet action (aspirin has antiplatelet action)
59. Aspirin difference from other NSAIDS:
a. has cardio beneficial effect
b. irreversible COX inhibitor
c. can't stop arthritis progression
d. can't remember 4th option
60. NSAID has CNS side effects:
b. sulindac
c. nabumetone
d. mefenamic acid
61. Aspirin overdose symptoms are all of the following except:
a. Hypothermia*
b. Metabolic acidosis
c. Respiratory depression
d. convulsions
62. Patient with gout history present to ER with gouty attack, which NSAID is
contraindicated:
a. Acetylsalicylic acid.
b. sulindac
c. Ibuprofen
63. NSAID given for ductus arteriosus:
a. Indomethacin
b. sulindac
64. When patient take prophylaxis therapy for gout:
a. more than One attack per year
b. Association with Kidney stones
c. ureate excretion 500 mg
d. blood urea level 10mg/dl
65.NSAIDS contraindicated with sulfa sensitivity:
a. Celecoxib
b. Ibuprofen
c. naproxen
d. indomethacin
66. Letrozole except:
a. mild androgenic SE
b. aromatase inhibitor
c. not cause endometriosis (true as it treat endometriosis)
d. no need corticosteroid co administration
67. Approved duration for the use of tamoxifen is:
a. 2 years
b. 5 years
c. 7 years
d. 10 years
68. Contraceptive contraindicated with lactating mother:
a. Progestin alone
c. combination*
d. copper T (loop)
e. condoms
69. Which Insulin type that's its reaction time is not effected by site of
administration?
a. Glargine (Lantus)
b. Isophane (Humuline)
70. Insulin that cannot be given as an IV:
a. Lispro (rapid acting)
b. Aspart (rapid acting)
c. Glulisine (rapid acting)
d. isophane
71. All indications of diabetes except:
a. Polyuria and unexplained weight loss
b. Random blood glucose of 200(true)
c. Fasting blood glucose of 140
d. Blood glucose level of 200, 2 hours post oral glucose intake
72. Insulin secretion form:
a. B cell
b. Alpha cell
73. Which drug has least effect of hypoglycemia?
a. metformin
b. glibenclamide
74. Patient was on cyclosporine and changes to tacrolimus. Tacrolimus comparison
with Cyclosporine all answers are true except:
a. more potent
b. less nephrotoxicity
c. longer duration
76. Sulfasalazine prevents the absorption of which element:
a. Folate
77. Azathioprine SE not dose related:
a. bone marrow depression
b. hepatotoxicity
c. Infection(true)
d. Pancreatitis
78. All DMARDs except:
a. prednisolone
79. Patient take DMARDs and after 2 weeks have eye problem which drug cause
that: (I am not sure it was in my exam)
a. sulfalazine
b. hydroxyquine
80. pro-kinetic drug has anti emetic effect:
Safe for renal impairment pt was in option
a. domepridone
b. Cisapride
81What is the medication that’s used in the treatment of glaucoma, medication-related edema,
heart-failure related edema?
Acetazolamide
82All can resist Beta lactamase except:
a.Augmentin
b.Doxcycycline
c.Dicloxacilln
d.Azythromycin 83Which is true about Digoxin MOA is:
Positive inotropic effect
84drug given for ductus arteriosus:
Indomethacin
85- which of the following cause depression in T-lymphocyte:abatacept
86- Which of the following S.E of B2 agonist ?
a. Hypokalemia
b. Hypomagnesia
c. Tremor
87- prostaglandin that can be used for glaucoma and eyelash Hypotrichosis
a. Lantoprost
b. Travoprost
c.bimatoprost
d. tafluprost
88- Acyclovir MOA:
a. DNA polymerase
89- Selective cox 2
Celecoxib
790Pentation through CSF )cerebrospinal fluid (depends on all except:
a.Lipid soulibility
b.Water soulibility
c.Mwt
d.protein binding
91- Not ACEIs SE:
Postural hypotension
92which of the following if administered with digitalis will not affect its action:
Captopril 93- Not to be used in Chrons disease:
a. Adalimumab
b. Certolizumab
c. Etanercept
d. Another biological treatment
e.
f. 94Which not used in heart failure:
g. Captopril
h. Digoxin (check please )
i. Nefidipine
j. Propranolol
k.
l. 95- Cromylin used in asthma to :
m. Decrease inflammation
n. Mast cell stabilizer
\1. Cyclosporine is more toxic in which route: .o
a. oral .p
b. IV .q
c. IM .r
d. SC .s
.t
2. IBS (irritable bowel syndrome) symptoms: ( In the exam mentioned that .u
pt eliminated all dairy products)
a. chronic constipation .v
b. chronic diarrhea .w
c. alternatively constipation and diarrhea .x
.y
3. Used in motion sickness except: .z
a. Hyoscine (scopolamine) .aa
b. Meclizine.bb
c. Promethazine HCL .cc
d. 4th option.dd
.ee
(The 4th option In My exam
was Propamide)
4. Which is not given for constipation? .ff
a. Lactulose (bulk laxative).gg
b. Loperamide (ttt of diarrhea).hh
c. Na-Pico sulfate (stimulant laxative) .ii
d. Docusate sodium (stool softener laxative) .jj
.kk
.ll
mm.
‫التتنسوني من صالح دعائكم وبالتوفيق والنجاح للجميع‬ Maryam Fat

19/8/2019- Version 1

This exam is similar to (19/3/2019)

 19/8/2019- Version 2

Assalamu alaikum, my exam was very easy. It was exact copy of 10 Jan 2018, 12 March 2018,
and 8 sept 2017. Please do include me in your dua. There was only 1 calculation, 120ml.
NAZREEN

1. Aspirin overdose symptoms are all of the following except:

a. Hypothermia
b. Metabolic acidosis
c. Respiratory depression

2. Mechanism of action and indications of aspirin:

Irreversible cox inhibitor, Inhibit platelet aggregation, PG inhibitor
3. aspirin difference from other nsaids
a. has cardio beneficial effect
b. irreversible COX inhibitor

3- Patient with gout history present to ER with gouty attack, which NSAID is contraindicated:
Aspirin
Note: The best NSAIDs to use with gout are: ibuprofen 800 mg TID and Indomethacin 25 to 50
mg QID

4- Picture of nail with thick texture and brown discoloration, Nail fungal infection DOC:
a. Fluconazole
b. Terbinafine
c. Griseofulvin

Note: According to the British Association of Dermatologists, the guidelines goes by terbinafine
OR itraconazole in the first line

5- Insulin that cannot be given as an IV:

a. Lispro ( rapid acting ..... .> short -acting )
b. Aspart ( rapid acting )
c. Glulisine ( rapid acting )
d. humuline (=isophane)( intermediate acting )
6-which Insulin type that's its reaction time is not effected by site of administration:
Glargine (lantus)

7- Comparison between Acyclivir with Valacyclovir:

Greater bioavailability, more potent, renal something
Ans all

8- Acyclovir is not effective in which virual infection? The options are NOT diseases but viruses
names!
a. Herpes zoster
b. Epstein-barr virus
C.CMV
d. herpes zoster

9- Type of penicillin that cannot be administered IV:

a. Penicillin G
b. Penicillin V
c. Others two options

10- Which iron dose is questionable:

a. 120 mg for 20 kg child
b. 90 mg for 15 kg child
c. 21 mg for 7 kg infant
d. 30 mg for 6 kg infant

11- Female is menopause, she experiences hot flushes, developed spinal osteoporosis which to
use?
Alenderonte
Note :If there is no alderonate in choices, the answer will be (estrogen and progesterone)

12- Lactating mother wants to use contraceptive which cannot be used:q19

a. Progestin alone
b. combination( estrogen and progestron)
c. copper T
d. condoms
Note: Estrogen only 1st CI
Combination 2nd CI

13-ACEI’s beneficial effect is caused by all of the following mechanisms except:

Vasodilation by inhibition of bradykinin metabolism
14- Patient taking ACEl (ramipril) which antacid should not be used:
a. Calcium carbonate
b. Magnesium
c. Aluminum
d. Potassium bicarbonate

15- Sulfasalazine prevents the absorption of which element?

F olate

16- Sulfasalazine should be given with which supplement?

Folic acid

17- Which is not given for constipation:

a. Lactulose (constipation)
b. Loperamide
c. Na-picosulfate (constipation)

18- New born infant had an infection he was given medication and kept under supervision; after
6 days he developed depressed breathing, gray coloration and rash, which drug is most likely
he's on?
Chloramphenicol (cause hemolytic anemia, protein synthesis inhibitor 50s subunit)

1 9 Female taking UTI medication, after few days she developed rashes and red spots on hands,
face, (they mean to say exposed areas) what medication she's on? Theyattached a hand that
shows red spots with the question.
Ans: ciprofloxacin
quinolones, ttc, acyclovir, amiodarone, diuretics)

20- A Kid took peanut butter and he’s allergic to peanut; he developed rashes and urticarial.
What type of allergic reaction is this?
a. Type 1
b. Type 2
c. Type 3
d. Type 4

21- Read about Acetaminophen (paracetamol) full mechanism of action, and its effect in Reyes
disease in kids with fever related to viral infection. you can choose more than one true
statement.
a. Acetaminophen has a great anti-inflammatory
b. inhibit PG in CNS
c. It has no risk in Reyes disease for kids with viral fever
d. irreversible cox3 inhibitor
Note: please check this answer

22- Not a side effect of (ACEIs) ramipril:

a. Hypokalemia
b. Low level of potassium

23- All of the following cause constipation except:

a. Bisacodyl
b. Morphine
c. Calcium
d. ACEI

24- Medication in an Inhalation route, can be used for long term to control asthma:
a. Salmetrol
b. Budesonide (Inhaled corticosteroids)

25- Which of the following is not used in TB treatment

a. INZ
b. Refamp in
c. Streptomycin
d. Ethambutol
e. PZN

26- patient with TB take more than one drug why??

To decrease the risk of developing drug-resistance

27- When giving ethambutol for a long duration, continuous follow-up/check-up is necessary
because of this condition:
a. Renal failure
b. Liver dysfunction
c. vision problem

28- DOC in bacterial meningitis:

Cefuroxime.
Note: Bacterial meningitis > Antibiotics as 3rd generation cephalosporin ( cefuroxime,
cefotaxime, ceftriaxone) and vancomycin may be added. Penicillin plus chloramphenicol

29- Patient was found to have an infection with gram +ve and -ve, which drug to use? We have
to choose a broad spectrum antibiotic
Amoxicillin

30- Pregnant woman with hypertension, what is the drug of choice?

Methyldopa

32-What is the medication that’s used in the treatment of glaucoma, medication-related

edema, heart-failure related edema?
Acetazolamide

33- Patient on three medication for HIV, after couple of years there is still evidence of infection,
enfuvirtide added to them which of the following is true:
The answer was the one that include the mechanism of action of enfuvirtide and how it’s
taken(SC).
They asked also about its low side effect profile and its reconstitution study them.

Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 subunit of the
viral envelope glycoprotein and prevents the conformational changes
required for the fusion of viral and cellular membranes. It works by
disrupting the HIV-1 molecular machinery at the final stage of fusion
with the target cell,
preventing uninfected cells from becoming infected. Enfuvirtide is a
biomimetic peptide that was rationally designed to mimic components of the
HIV-1 fusion machinery and displace them, preventing normal fusion.
Enfuvirtide is an antiretroviral drug used in combination therapy for
the treatment of HIV-1/AIDS.

34- What is the antiviral that’s the most suitable for HSV infection? Get a general idea about
HSV viral infection please
Acyclovir

35- Pharmacist monitoring of drug despising and refill will give an idea about:
a. Drug utilization
b. Drug disposal
c. Drug adherence
36-What’s the type of study that’s MOST reliable? Robust( it is same as reliable don’t confuse
with it
a. Cohort randomized
b. Case study
c. Case report
d. Case scenario

37- What’s the type of study that’s LEAST reliable? Memorize types of studies please
a. Cohort randomized
b. Case study
c. Case report
d. Case scenario

38- Manufacturer recall of medication from pharmacy is called:

Voluntary call

39- Approved duration for the use of tamoxifen is:

10 yrs
40- DOC for status epilepsy:
Diazepam
Note: 1st 🡪 Diazepam 2nd 🡪 lorazepam/midazolam 3rd 🡪 phenytoin

41-patient with panic attack what is DOC

a. buspiron
b. benzodiazepan
c. antidepressant
d. barbiturate

42- benzodiazepines are all except:

a-anticonvulsant
b-muscle relaxant
c-Antero amnesia
d-anti pscychotic

43- Patient has a problem in bowel emptying, he develops pain while passing stool. Which is the
least likely condition to cause this problem?
Hyperthyroidism

44- Patient take DMARDs and after 2 weeks have eye problem, Which DMARD
related to vision problem:
hydroxyquine

45- Patient present to ER because of gouty attack, he was given NSAID, when should we
consider giving prophylaxis therapy for gout: ((you can choose more than one))
- more than One attack per year
- Association with Kidney stones
- Urate excretion more than 500 mg
-Uric acid more than 10mg

46- Digoxin cannot be used in which condition:

a.Heart failure
b.Along with ACEI and diuretics
c.In ventricle atrial fibrillation
d.Left diastolic HF

47- All of the following are indications of diabetes except:

a. Polyuria and unexplained weight loss
b. Random blood glucose of 200
c. Fasting blood glucose of 140
d. Blood glucose level of 200, 2 hours post oral glucose intake

48-insulin secrets form which cell ?

B cell

49-All can resist Beta lactamase except:

a.Augmentin
b.Doxcycycline
c.Dicloxacilln
d.Azythromycin

50- Study acetyl salicylic acid full mechanism of action as an analgesic and cardio protective.
Acetyl salicylic acid (aspirin)characterized by :
● cardio protective action
● Has antiplatelet action
● Analgesic and antipyretic
● Has anti inflammatory action
● All of the above.
51-which drug has least effect of hypoglycemia:
Metformin or ascarbose
52- Azathioprine SE not dose related
infection

53- which of the following no need for antibiotic dose adjustment ?

a.hypercholestrylemia
b.elderly patient
c.renal disease patient
d.AIDS

54- Patient with TB has discoloration in urine (reddish color) on which medication?
Rifampicin

55- patient on cyclophosphamid has developed hematuria due to release of which :

a. phosphoramide mustard
b. Acrolein
c. Mensa

56- Which is true about Digoxin MOA is:

Positive inotropic effect

57 drug given for ductus arteriosus:

Indomethacin

58- which of the following cause depression in T-lymphocyte:

abatacept, cyclospoirn, tacrolimus, sirolimus baciliximb, daclizumab (check please)

59- Which of the following S.E of B2 agonist ?

a. Hypokalemia
b. Hypomagnesia
c. Tremor

60- Patient has irritable bowel disease, the doctor advice the patient to remove dairy products
from his diet, which symptoms patient have:
a- chronic Constipation
b- chronic diarrhea
Note: dairy products cause constipation
61- Etoposide cause DNA damage through inhibition:
a. Topoisomerase I
b. Topoisomerase II
c. Topoisomerase III
d. Topoisomerase IIII

62- prostaglandin that can be used for glaucoma and eyelash Hypotrichosis
a. Lantoprost
b. Travoprost
c.bimatoprost
d. tafluprost

63- Acyclovir MOA:

a. DNA polymerase

64- micro-organism resistant mechanism against antibiotics:

Enzymes

65- Aortic dissection DOC along with B blocker:

Sodium nitroprusside

66- Antibiotic that cause hand rash:

cipro

67- Patient diagnosed with hodgkin lymphoma. Doctor decides to stop him from dairy product.
Which amino acid patient will avoid:
Tyramine

68- 5 days old infant given antibiotic which cause apnea and gray coloration for the baby?
Chloramphenicol
69- smoker with COPD , what is the drug of choice ?
a. Busonide
b. Ipratopium
c. Theophyllin
d. Montelukast

70- A physician wants to switch a terminally-ill patient from slow release morphine sulphate
tablets, 15 mg twice daily, to a liquid morphine sulphate dosage form because the patient has
difficulty in swallowing tablets. If a morphine sulphate solution containing 5 mg per mL is
prescribed q4h, what volume should be dispensed for a 20 day supply to provide the same pain
relief as the tablet regimen?
a.20 mL
b.60 mL
c.100 mL
d.120 Ml
‫المسألة الوحيدة في هذا األمتحان‬

71-Action of insulin except:

Decrease glucose production in liver
Decrease liver glucose uptake
Insert glucose in muscle and adipose tissue

72- Which is contraindicated with sulfa sensitivity

Celecoxib

73- Selective cox 2

Celecoxib

74 Pentation through CSF )cerebrospinal fluid( depends on all except:

a.Lipid soulibility
b.Water soulibility
c.Mwt
d.protein binding
75-female take antibiotics and suffer from ear problem which AB cause this:
Amikacin

76-used in motion sickness except:

Cinnarazine
Hyoscine
Scopolamine
Promethazine HCL
4th option (I can’t remember this choise, but all of these 4 choices used for motion sickness)

77- Study heparin mechanism of action.

injectable anticoagulant mechanism of heparin:
-inhibit platelet aggregation
-inhibit antithrombin 3
Sorry dont remember answer
78- Not ACEIs SE:
Postural hypotension

79-which of the following if administered with digitalis will not affect its action:
Captopril

80- Patient was diagnosed with malignant glioma and doctor decides to put him on
chemotherapy. Which of the following is DOC:
Temozolomide
In my exam other options were mentioned study this one well I chose (check please)

81- Cyclosporine SE will increase if given in which route:

IV

82- Study letrazole mechanism of action and side effects, you can choose more than one
answer.
I choose aromatase inhibitor with no androgen Side effects.
83- True about SSRI:
Safest one to use for long term.

84- Used in emergency HTN:

Na nitroprusside

85- Associated with CNS side effects:

Mefnamic acid

86- Which of the following causes tachycardia:

a.B blocker
b.verapamil
c.diltiazem
d.isosorbide dinitrate

87- patient with ED (erectile dysfunction) and take Sildenafil which CI with sildenafil:
isosorbide dinitrate

88- Not a monoclonal antibody:

a.infliximab
b.etarnecept
c.adalimuab
d.cetrilizumab

89- Not to be used in Chrons disease:

a. Adalimumab
b. Certolizumab
c. Etanercept
d. Another biological treatment

90- Which not used in heart failure:

Captopril
Digoxin
83- True about SSRI:
Safest one to use for long term.

84- Used in emergency HTN:

Na nitroprusside

85- Associated with CNS side effects:

Mefnamic acid

86- Which of the following causes tachycardia:

a.B blocker
b.verapamil
c.diltiazem
d.isosorbide dinitrate

87- patient with ED (erectile dysfunction) and take Sildenafil which CI with sildenafil:
isosorbide dinitrate
88- Not a monoclonal antibody:
a.infliximab
b.etarnecept
c.adalimuab
d.cetrilizumab

89- Not to be used in Chrons disease:

a. Adalimumab
b. Certolizumab
c. Etanercept
d. Another biological treatment

90- Which not used in heart failure:

Captopril
Digoxin
Nefidipine
Propranolol

91- Cromylin used in asthma to :

Decrease inflammation
Mast cell stabilizer

92- patient have hair loss (bladness) ‫ الصلع‬, the doctor give him topical treatment is:
Minoxidil

93- The DOC for acute attack of asthma:

Albuterol

94- patient came to the pharmacy and have chest pain, the pharmacist decide to turn the
patient to cardiologist because:

The pain radiating on neck and shoulders, arms and jaw

95- The best advice to a patient taking corticosteroid inhaler for asthma (you can choice more
than 1 choice)

a) Take rapid breath after pressing the inhaler

 b) Hold your breath for 10 seconds after complete inhalation

c) rinse your mouth with water after using the inhaler

d) keep one finger distance between your lips & the inhaler

96- Patient was on cyclosporine and changes to tacrolimus. Tacrolimus

comparison with Cyclosporine: ) exept
a. more potent
b. Less side effects (less nephrotoxicity )
c. longer duration
d. all of the above
Note: read about th is question
97- All are true about benzodiazepine except:

● Cause amnesia.
● Cause muscle relaxant.

Need 1-4 week for the effect

1-2w

9/9/2019- Version 1

(My exam was so easy, most of the questions came as case studies, but once you
read the questions you will know what to answer). All the questions are repeated
from all 2018 files, also from file: Agwa 1/9/2019

1) Which one of the following penicillin’s not administered as IV?

a) Penicillin G
b) Penicillin V
c) Ampicillin
d) Amoxicillin

2) Female taking UTI medication, after few days she developed rashes
and red spots on hands, face, neck (ie: exposed areas) what medication
she's on?
a) ciprofloxacin
b) amoxicillin
Note: Fluroquinolones cause photosensitivity as a side effect.

3) Antibiotic that can resist B lactamase producing bacteria:

a) cefopodoxime
b) cepoperazone
c) Azithromycin
d) cefazoline

4) DOC for bacterial meningitis:

a) Cefuroxime
b) Tetracycline
c) Chloramphenicol

5) least used for beta lactamase producing bacteria

a) amoxicillin + clavulanic acid
b) Dicloxacillin (nowadays it’s least to be used)
c) Erythromycin
d) Doxycycline

6) DOC of pregnant woman with UTI?

A. Cefuroxime
b. cephalexin

7) Acyclovir is not effective in which viral infection?

a. Herpes zoster
b. Epstein-barr virus
C. Cytomegalovirus (CMV)
d. herpes zoster

8) Which antiviral is most suitable for HSV encephalitis infection?

a) acyclovir
b) foscanet

9) Treatment with which biological is associated with reduction in T

effector memory cells
a) Efalizumab
b) Alefacept --- double check*
c) Adalimumab
d) Etanercept

10) All are beneficial effects of ACE inhibitors has in heart failure
except?
a) Have positively ionotropic effect --- double check*
b) Decrease vasoconstriction by inhibiting angiotensin II
c) Increase vasodilation by bradykinin inhibition
d) Decrease aldosterone secreation

11) Which one not reduce the effect of digitalis?

a) Cyclosporin
b) Azithromycin--- double check*
c) Captopril
d) Ciprofloxacin

12) Sulfasalazine reduce the absorption of?

Folate

13) Which supplement must be taken with sulfasalazine?

Folic Acid

14) Which one is not DMARD?

a) Prednisolone
b) Methotrexate
c) leflunomide
d) Infliximab
15) A physician wants to switch a terminally- ill pt. from slow release
morphine sulphate tab. 15 mg bid to a liquid morphine sulphate dosage
form, because pt has difficulty in swallowing tab. If a morphine sulphate
solution contain 5mg per ml is prescribed q4hr … What volume should
be dispensed for a 20 days supply to provide the same pain relief as the
tab. Regimen??

a. 120ml

16) Which iron dose is questionable?

a. 120 mg for 20 kg child
b. 30 mg for 6 kg infant
c. 21 mg for 7 kg infant
d. 90 mg for 15 kg child
Note:
Child: every 1 kg = 6mg
Infant: every 1 kg = 3mg

17) Anti-fugal for nail infection (with a pic) is

Terbinafine

18) Which anti-TB is not used as first line?

Streptomycin

19) Which chemotherapy used in the treatment of Malignant Glioma:

Carmustin

20) Azathioprine, which one of the following is not a dose related side
effects (Idiopathic Syncretic)?
Infection
21) Case about a woman took overdose of aspirin, what symptoms she
will not experience?
a) Hypothermia
b) Metabolic Acidosis
c) Respiratory Depression
d) Convulsions

22) Most common side effect of salbutamol is?

Tremor

23) Smoker with COPD what is the DOC?

Ipratropium

24) The DOC for acute attack of asthma?

Albuterol

25) Which NSAID that works well in RA but it causes GIT disturbance
and is the one used in the closure of Patent Ductus Arteriosus (PDA)?
Indomethacin

26) Maximum duration for the use of tamoxifen is?

a) 2 years
b) 5 years
c) 7 years
d) 10 years

27) which statement is true about letrazole?

a. mild androgenic SE, aromatase inhibitor.
b. aromatase inhibitor, not cause endometriosis, mild androgenic SE.
c. aromatase inhibitor, no need corticosteroid co administration, mild
androgenic SE.
d. aromatase inhibitor, no need corticosteroid co-administration,
not cause endometriosis.
28) (Case) An HIV patent was on multiple antivirals and there still
evidence of infection, Enfuvirtide was added to his regimen, what true
about it?
a. integrase inhibitor
b. S.C
c. can used without reconstitution
d. low side effects
e) b and d

29) Which biological treatment is not used in Chron’s Disease ?

a) infliximab
b) etanercept
c) adalimumab
d) cetrilizumab

30) Which anti-TB that needs optic monitoring while using it? Or maybe
it was which one is least to cause urine discoloration? (am not sure
what was the question, anyway the answer for both is >>>
Ethambutol

31) (Case) Treatment of Sickle cell anemia?

Hydroxy urea

32) (Case) Broad spectrum antibiotic for meningitis that caused by both
G+ and G- bacteria?
amoxicillin

33) The use of broad spectrum for long term can cause which infection?
a) heleicobacter pylori
b) E.coli
c) shigella
d) Clostridium difficile = (which causes Pseudomembranous Colitis)
34) Mechanism of action of acetaminophen?
a. Small risk of Reyes syndrome (Paracetamol has no risk on Reyes
Disease in kids with viral fever)
b. Anti-inflammatory
c. Inhibit PG in CNS
d. No platelet action
e) c and d

35) Mechanism of action of Acetyl Salicylic Acid?

a. has cardio beneficial effect
b. irreversible COX inhibitor
c. can't stop arthritis progression
d. a and b

36) Patient was on cyclosporine and changes to tacrolimus) Tacrolimus

comparison with Cyclosporine, what’s true about tacrolimus?
a) longer duration, less nephrotoxic, need low dose of corticosteroid
along with it.
b) lower rejection rates, less potent, less nephrotoxic
c) short duration, less nephrotoxic, need low dose of corticosteroid
along with it.
d) lower rejection rates and it need low dose of corticosteroid along
with it.
Note: I don’t remember what the rest choices were about exactly, but I
do remember that all were wrong, and d was right. (The question came
like this)

37) (Case) A patient suffers from esophagus reflex, which additional

symptoms if happened the patient should be referred to cardiologist?
a) mild pain in arms
b) pain in central abdominal
c) pain that spread to jaws, neck, shoulders and arm
d) pain in illu fosse "something like this"

38) (Case) Patient has a problem in bowel emptying, he develops pain

while passing stool. Which one is not a differential diagnosis of
constipation?
a) Bowel obstruction
b) IBD
c) Carcinoma
d) hyperthyroidism

39) (Case) A patient has IBS (irritable bowel syndrome) and the
physician advised her to eliminate dairy products from diet for about 3
months, which symptom the patient have?
a) Chronic constipation
b) Chronic diarrhea
c) Alternatively constipation and diarrhea (this answer is true)

40) Pro-kinetic drug has anti emetic effect?

a) Domepridone
b) Cisapride

41) Which contraceptive pill is contraindicated with lactating mother?

a) Progestin alone
b) Combination
c) Copper T (loop)
d) Condoms
Note: The first answer must be (estrogen) alone , if it’s not there then
the 2nd answer will be (Combination: estrogen and progesterone)

42) Female is menopause, she experiences hot flushes, developed

spinal osteoporosis which to use?
a) Alendronate
b) Estrogen and progesterone
c) progestin
Note: The first answer must be alderonate, if it’s not there then the 2nd
answer will be (estrogen and progesterone)

43) All are factors affect cerebro-spinal fluid (CSF) penetration Except?
a) Lipid solubility
b) Water solubility
c) Molecular weight
d) Plasma protein binding

44) Which is not given for constipation?

a) Lactulose
b) Loperamide
c) Na-Pico sulfate
d) Docusate sodium

45) Pharmacist monitoring of drug dispensing and refill will give an idea
about?
a) Drug utilization
b) Drug disposal
c) Drug adherence

46) What type of study that’s MOST robust?

a) Cohort Randomized Trials
b) Case study
c) Case report
d) case series

47) What type of study that’s LEAST robust?

a) Cohort Randomized Trials
b) Case study
c) Case report
d) Case scenario

48) Manufacturer recall of medication from pharmacy is called?

a) Voluntary call
b) Immediate recall
c) involuntary call

49) Patient with ED (erectile dysfunction) and take Sildenafil which one
is absolute CI with sildenafil:
isosorbide dinitrate

50) True about SSRIs?

a. Most effective in chronic anxiety disorders
b. Give effect 1-4 weeks
c. Can't be first line for anxiety disorders

51) Benzodiazepines all true indications EXCEPT:

a) Muscle relaxants
b) Anxiolytics
c) Antrograde amnesia
d) Antipsychotics

52) DOC (vasodilator) with b blockers in treating aortic dissection?

a) minoxidil
b) hydralazine
c) diazoxide
d) sodium nitroprusside

53) Contraindicated in CHF?

a) Hydrochlorothiazide
b) Nefidipine
c) Captopril
d) Digoxin
54) Which anti-hypertensive that has short acting effect and used for
hypertension emergency?
a) Sodium nitroprusside
b) Clonidine
c) Captopril

55) Which medicine used to treat glaucoma, heart failure-related

edema, medications-related edema, reduces intraocular pressure after
surgery?
Acetazolamide

56) Which of the following causes tachycardia?

a) Propranolol
b) Verapamil
c) Diltiazem
d) Isosorbide dinitrate

57) ACEI can increase level of?

a) Sodium
b) Potassium
c) Calcium
d) Magnesium

58) Ramipril not physiological actions?

a) Hypokalemia
b) Low level of potassium
c) Increased renin in plasma
d) Angiotensin II receptor inhibitor
Note: Check this question again

59) (Case) a patient is using 4 drugs (enalapril, simvastatin, amiodarone,

….), which one of them can cause dry cough?
Enalapril
60) (Case) Female patient having UTI and she started feeling decreased
hearing, which antibiotic she’s on?
Amikacin

61) Patient with gouty arthritis, which NSAID is contraindicated?

a. Aspirin.
b. sulindac
c. Ibuprofen
d. Mefenamic acid

62) which NSAID has CNS side effects?

a. Aspirin.
b. sulindac
c. Ibuprofen
d. Mefenamic acid

63) A patient present to emergency with gout, he received NSAID when

a prophylaxis therapy for gout is considered?
a. More than One attack per year
b. Association with Kidney stones
c. Ureate excretion 500 mg
d. Blood urea level more than10mg/dl
e. b and d

64) All used in motion sickness except?

a. Hyoscine (scopolamine)
b. Meclizine
c. Promethazine HCL
d. Propamide

65) Which NSAID is more selective to cox-2 more than cox-1:

Celecoxib
66) Which NSAID is contraindicated in sulfonamide sensitivity?
Celecoxib

67) (Case) of female feels panic when speaking to audience. Treatment

of panic attack?
a) benzodiazepines
b) TCAs
c) antipsychotics
d) SSRIs
e) Buspirone

68) A Kid took peanut butter and he’s allergic to peanut; he developed
rashes and urticarial. What type of allergic reaction is this?
a. Type 1 = Allergy to food
b. Type 2
c. Type 3
d. Type 4

69) Patient with TB take more than one drug why?

a. To decrease the risk of developing drug-resistance
b. To shorten infection
c. To shorten duration of treatment
d. Less side effects
e. make combination ….

70) When giving ethambutol (anti-TB) for a long duration, which one of
the following check-ups is necessary?
Visual Acuity

71) Cyclosporin effect increased by which rout?

Intravenous
72) Not caused constipation?
Bisacodyl

73) Not used to relieve constipation?

Loperamide

74) Which Insulin type that its reaction time is not effected by site of
administration?
Insuline Glargine (Lantus)

75) Which Insulin type that cannot be given as an IV?

Insuline isophane (Humuline)

76) New born infant had an infection he was given medication and kept
under supervision; after 6 days he developed depressed breathing, gray
coloration and rash, which drug is most likely he's on?
Chloramphenicol

77) The best advice to a patient taking corticosteroid inhaler for

asthma?
Hold your breath for 10 seconds after complete inhalation and rinse
your mouth with water after using the inhaler

78) A child suffered from acute asthma attack and diagnosed with
asthma, which single treatment for long term use to prevent
exacerbations of asthma?
a) Salmeterol
b) Ipratrobuim
c) Salbutamol
d) Corticosteroid

79) MOA of Cromylen Na is?

Inhibits mast cells degranulation
80) Main MOA of anticoagulants is?
Activating protein synthesis, anti-thrombin III

81) Acyclovir competes with dGTP as a substrate for viral (MOA of

Acyclovir)
DNA polymerase

82) Etoposide cause DNA damage through inhibition of ?

a. Topoisomerase I
b. Topoisomerase II
c. Topoisomerase III
d. Topoisomerase IIII

83) Prostaglandin that can be used for glaucoma and approved to be

used for eyelash Hypotrichosis?
a. Lantoprost
b. Travoprost
c. bimatoprost
d. tafluprost

84) All are Actions of insulin except?

a. Decrease glucose production in liver
b. Decrease liver glucose uptake
c. Insert glucose in muscle and adipose tissue
d. Decrease blood glucose level

85) A child with hairline and bald batches, the doctor advise him to take
which topical treatment?
Minoxidil
86) Which of the following no need for antibiotic dose adjustment?

a. Patient with hypercholesterolemia

b. Elderly patient

c. Patient with renal disease

d. Patient with AIDS

87) All are indications of diabetes except?

a) Polyuria and unexplained weight loss
b) Random blood glucose of 200
c) Fasting blood glucose of 140
d) Blood glucose level of 200, 2 hours post oral glucose intake

88) Which medicine used to treat influenza A and B, act as a potent

inhibitor …, cleaves sialic acid?
Oseltamivir

89) The metabolic effect of combining glucocorticoid and tacrolimus is?

a. Hypocalcemia

b. Hyperglycemia

c. Hyperlipidemia

d. Hyponatremia
90) Which one of the following antacid must be used in caution with
ACE inhibitors?
K+ bicarbonate

91) (Case) A patient is taking procarbazine an anticancer used to treat

Hodgkin Lymphoma disease. Which amino acid is contraindicated
with ?
a) phenylalanine
b) tyramine
c) valine
d) leucine

92) Patient on cyclophosphamide has developed hematuria due to

release of which substance?
Acrolein

93) Valacyclovir benefit over acyclovir?

a) better bioavailability
b) better tolerance
c) less renal impairment
d) all of them

94) Which drug has least effect of hypoglycemia?

metformin

95) DOC for status epilepsy is?

a) clonazepam
b) diazepam
c) Phenobarbital
96) A way for microorganism to resist antibiotic is through?
Enzymes

97) Digoxin is CI against?

Diastolic Failure

98) In pancreas, which cell is responsible to secrete insulin?

Beta Cells

99) Analgesic used during acute MI?

Morphine

100) Which medicine cause reddish Colour of urine?

Rifampicin

Hope u all do best in your exam …. Good Luck

9/9/2019- Version 2

‫مسائل وكانت‬7 ‫كان فيه‬2019/2/19 .. ‫االمتحان الحمد لله كان مكرر من امتحان‬
‫سهله‬
‫الحمد لله وتعويض بشكل مباشر ما عدا وحده جديده لكن سهله و االسئلة سهلة‬
‫لكن مش‬
‫مباشرة … وبالتوفيق للجميع‬

Diaphragm 1:

2.MTC mean: maximum safe concentration

3.MEC mean : minimum effective concentration
4. Above MTC: toxic
5. Area under MEC : Not effective.
6-Which of the following used to make mydriasis in checking refractive
errors?
Atropine
Tropicamide
NB. Atropine is not used now due to its prolonged mydriatic effect
7- case scenario about female patient have GOUT was weak & dizzy &
fatigue and
another problems like she can’t raise her hand and having some blood
disorders like
agrnaulocytosis and leucopenia and type of anemia which anti gout are
probably to cause
this Side effects :
a- allopurinol
b- colchicine
C- probencid
Answer: B
8-Pt in the ICU for 3 days which antacid is used :-
2
a-PPIs
b-H2 blocker
c-sucralfate
Answer: a
9- Drug used in IBD(Inflammatory bowel disease) remission:
- infliximab
10- SIADH(Syndrome of inappropriate antidiuretic hormone) cause all
of the following
except:-
a-hyponatremia
b-hypernatremia
c-water excess
d-Inadequate vasopressin production
Answer: B
11- Case of a patient asked for an OTC for her constipation, she said
that she
experienced painful defecation. You decided to transfer her to a
physician because you
think she have
a.Anal fissure
b.Anal fistula
c.Rectal fissure
d.Rectal abscess
Answer: a
12- emulsion inversion:
a-conversion of W/O emulsion to O/w emulsion and vice versa
13- Conductivity in emulsion, the dispersed phase for such emulsion is:
a- Aqueous
b- Non aqueous
c- Aqueous and non aqueous
Answer: B
3
14- CMAX. :
answer..A ( or ..max. drug conc. in plasma ...or. max. serum conc. )
15- TMAX. :
a. max. time to reach drug max. conc.
b. time required to reach max. plasma conc.
answer..B
16- conc. at CMAX. is 23.5 ,the T will be:
a. 2hrs
b.3hrs
c.4hrs
d.5hrs
answer..B
17- Mechanism of action of Digitalis all is true expect :
a. inc. contractility
b. dec. vascular resistance
c. reduse ventricular rate in atrial fibrillation
d. have modify effect on central nervous system
answer.. B
18- patient admitted to ER with chest pain, diagnosed as prinzmetal
angina ,regarding this
angina which is true :
a.Occur at rest not associated with physical activity
b.Associated with artery spasm
c.Associated with atherosclerosis
d.Not responsive to nitroglycerin and CCB
answer...all true except D
4
19- side effect of all anti-arrythmic :
a.blurred vision
b. torsade de points
answer.. B
20- old patient admitted with arrhythmia ,regarding arrthmia which is
true:
a.most common cause is re-entry
b.antiarrythmia more safer
c.most ttt is CCB and NA channel blocker
d.SA is pace of heart contraction
Answer: all true except b
21- Advantage of IV route is true: (without except)
a.used in emergency
b.dose can be titrated
c.fastest
d. safe and convenient
answer..A ,B,C---TRUE
22- Foam in pharmacy spray:
a. Topical
b.Burn dressing
c. Rectal
d. all
answer...D
23-If dose of drug is 0.2 ml ,How many dose will be in 15ml :
answer.. 15ml /0.2 ml =75 ml
24-How many gram of 5% ointment will be prepared from 2 gm :
answer.. (5%= 5gm ----100 ,,2gm---?
2*100/5=40 gm
25- How many gram will be in 250 ml of 5% solution :
answer.. 5% = 5gm ---100ml
??--------250ml
= 250 *5 /100=12.5 gm
5
26-Particle size affect the following :
a.solubililty
b.dissolution
c.content-content uniformity
d.suspend abililty
e.penetrability
answer...ALL
27- Pt. have lower HDL and lower dyslipidemia managment :
a. atrovastatin
b. Niacin
c. fenofibtates
d.Rosuvastatin
answer... B
28- Patient got stung by bee, suffered from severe bronchospasm, and
severe
hypersensitivity reaction, which drug is most suitable for this case:
Dopamine
Norepinephrine
Epinephrine
Antihistaminic
answer.... Epinephrine
29- conductivity test ,dilution test, dye test used for :
a- Suspension
b- Emulsion
c- Foam
d- Gel
answer...B
30- Morphine cause tolerance except :
a- Rispiratory depression
b- Euphoria
c- Pint point pupil
Answer: c
6
31-A child unconscious in starting or cessation of activity that last less
than 30 seconds
What is the type of seizures he has:
a. Simple partial
b. Complex partial
c. Absence
d. Myoclonic
Answer: C
32- patient with acute mania , which drug isn’t effective:
answer... phenytoin
33- ttt. of STatus Epilepsy :
answer... phenytoin
N.B: used in ttt: 1- benzodiazepines (diazepam)
2- Clonazepam 3- phenytoin
34- IN absence seizure all of the following prescribed except:
a- ethosuxamide
b- diazepam
c- lamotrigine
d- carbamezapine
answer.... D
35- patients with blood pressure 220/150 and glaucoma which drug
should be avoided:
a-labetalol
b-fendolopam
c-Na nitropuroside
d-nitroglycerin
answer... B
36- TCA metabolized by :
answer... CYP450
37- TCA act on all ,EXCEPT :
a. alpha adrenoreceptor
b. beta adrenoreceptor
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c.Muscrinic receptor
d. Histamine receptor
Answer: B
38- TCA used in all except :
a-panic attack
b-schizophrenia
c-Migrain
d- Neuropathic pain
answer... B
39- DOSE pt.75 mg ,How ml. 125mg /5ml solution :
answer.... 125mg -----5ml
75mg ------??
= 75 *5/125=3ml
40- patient with infection sensitives to tetracycline , pt is renal impaired
Which one of
tetracyclines is suitable for him:
a- Doxycycline
b- Minocycline
c- Tetracycline
answer.. A
41- patient with pharyngitis, the pt was penicillin allergic but the
organism is penicillin
sensitive ,injectable abtibiotics is not preferred in this situation ,what is
the safest and
effective alternative
a- Penicillin
b- Cephalosporin
c- Azithromycin
d- Tetracycline
Answer: c
42- phenytoin S.E. all , Except :
a-gingival hyperplasia
b-nystagmus
c-nephrotoxicity
d-steven-gohnson syndrome
8
answer.... C
43- Bacteria move by :
answer... Flagella
44- NOT Fungus :
answer.... E.COLI
45- case : parkinson :
Tremor & agitation i
difficulty to initiate &
voluntary ii
movements
abnormalities in
postural and normal iii
position

answer ... ALL

46- drug not used in Parkinson:
a-levodopa
b-bromocriptine
c-Chlorthalidone
d-MAOI
answer... C
N.B.: NOT USE IN PARKINSON:
( 1- Chlorthalidone 2- Chlorpromazine 3- Halopridol )
47- B adrenergic agonist least effect+:
answer... begin prostatic hypertrophy
48- TB. medication ,INH,PYZ,RMP ,which is the SE. of INH :
answer... peripheral neuropathy
49- Affect dissolution rate, absorption rate, content uniformity and
stability:
a. particle size
b. size distribution
c. interaction with surface molecule
d. all
answer... D
50- antiviral used for influenza and , Parkinson:
9
a-amantidine
b-lamuvidine
c-zidovudine
answer.... A
51- mitochondrial toxicity,, ANTIVIRUAL used:
a-lamivudine
b-amatidine
c-zidovudine
answer.... C (N.B. : 1- Stavudine 2- Zidovudine)
52- antiviral used in HBV:
a-lamivudine
b-amatidine
c-zidovudine
d. stavudine
answer... A
53- patient with HIv , the CD4 less than:-
a-200
b-400
c-500
d-600
answer... A
54- CD4 bind to which antigen in the HIV positive Pt:
a-T lymphocyte
b-B lymphocyte
c-macrophages
d-natural killer
answer... A
55- 50% alchohol is to be diluted with purified water, how many parts
of purified water
(0% alchohol) to prepare 20% preparation:
a- 30parts water + 20 parts 50% alchohol.
b-30 part alcohol +20 part water.
c-50 part alcohol+50 part water
10
answer... A
56- long case have arrhythmia+ COPD can use except
a-digitalis
b-verpamil
c-amiodarone
d-diltiazem
Answer: c
57- pilocarpine used in all of the following except:-
a-acute attack of closed angle of glaucoma
b-standard drug for close angle glaucoma
c-used alternatively with mydriatic to separate the iris
d-standard one for open angle glaucoma
Answer: d
58-question all about immune reconstitution inflammatory syndrome
except
a-not effected by glucocorticoids or antiinflammatories
b-the action of antiviral starts
c-the patient start to respond to ttt
Answer: a
59- Pt is taking anti-seizure medication and wants to stop it, which of
the following low
recurrence:-
a- EEG abnormalities
b-frequent seizure attack
c-cerebral known lesions
d-seizure began at early age
Answer: d
60- In myasthenia gravis which is true except:
A. Autoimmune disease againtACh receptors
b. Diagnosed by edrophonium
C. Not treated with cortitcosteroids
Answer: c
61-patient with hypertension put on antihypertensive drug, after few
months
11
developed heart failure manifested as reduction in heart rate and
contraction,
which antihypertensive drug patient put on:
a. Lisinopril
b. verpamil
c. prozosin
d. Thiazide diuretic
answer.. B
62-Nitroglycerin not use in route of administration :
or .(about nitroglycerin least favorable route of administration :)
a. oral
b. buccal
c.Transdermal
d. sublingual
answer... A
63-side effect of all anti-arrythmic :
a.blurred vision
b. torsade de points
answer.. B
64- old patient admitted with arrhythmia ,regarding arrthmia which is
true:
a.most common cause is re-entry
b.antiarrythmia more safer
c.most ttt is CCB and NA channel blocker
d.SA is pace of heart contraction
answer..A ,C,D –TRUE
65-chest x ray show what like to cause this infection :
answer... MYcobacterium avium complex
66-Morphine cause tolerance except :
a- Rispiratory depression
b- Euphoria
c- Pint point pupil
answer... C ( least tolerance ..pint point pupil)
12
67-Meperidine not suitable for use long time beacuse:
a-Nephrotxicity
b- Neurotoxicity
c- Cardiotoxicity
answer... B
68-TCA used in all except :
a-panic attack
b-schizophrenia
c-Migrain
d- Neuropathic pain
answer... B
69-B adrenergic agonist least effect+:
answer... begin prostatic hypertrophy
70-question all about immune reconstitution inflammatory syndrome
except
a-not effected by glucocorticoids or anti-inflammatories
b-the action of antiviral starts
c-the patient start to respond to ttt
answer: a
71-Primaquine is contraindicated in all of the following except:
a-SLE,RA
b-G6PD deficiency
c-Lactating female
d-Pregnancy
Ans: c
72- case about patient recently widowed, is suffering from severe
depression, is
taking imipramine
TCA block the uptake of :
a-serotonin
b-norepinephrine
c-Serotonin and norepinephrine
d-dopamine
Ans: c
13
73- case about patient taking propranolol as cardio-protective in
myocardial
infarction, all of the following are effects of propranolol except:
a-reduce infarct size
b-increased O2 demand
c-decreases mortality and morbidity
Ans: b
74- Long case about Parkinson patient:
What is the effect of carbidopa on levodopa:
a-Decrease its metabolism in the CNS
b-Decrease its peripheral decarboxylation to dopamine
c-Decrease its elimination
Ans: b
75- Which of the following is not fungus:
a-Yeast
b-Mushroom
c-Mucor
d-Escherichia
Ans: d
76-Which drug is high alert and should always be properly labeled and
separated:
a-Epinephrine inj (epipen)
b- Norepinephrine 3- …….
Ans: a
77- A 70-yr old diabetic patient on oral hypoglycemics and suffering
from
hypertension, which of the following antihypertensive drugs is not
recommended:
a-Losartan
b-Enalapril
c-Hydrochlorothiazide
d-Atenolol
Ans: d
78- All of the following are side effects of thiazide diuretics except:
a-Hyponatremia
b-Hypocalcemia
14
c-Hyperuricemia
d-Hypervolemia
Ans: b
80- Loop diuretics are contraindicated in all of the following except:
A-Renal diseases
b-Sensitivity to sulfonamides
c-Anuria despite using loop diuretics
d-Na and water depletion
Ans: a
81- Which of the following is true about dry cough associated with ACEI
:
a-Mediated by bradykinin and substance p
b-In women more than men 3- Develops within 6 months
c- Dose related
Ans: c
82- effect of levodopa decreased with which vitamin:
a-B12
B-B6
C-B2
D-B3
answer... B
83- effect of levodopa on body diminished :
a- after less than 3 yrs
b-after 2 yrs
c-after 3 yrs up to 5 yrs
d-after 5 yrs
answer.. C
84.high Therapeutic index mean:
answer... no side effect
85-All of the following are non-competitive acetyl cholinesterase
inhibitors, except:
a-Donepezil
b- Rivastigmine
15
c- Galantamine (reversible and competitive ache inhibitor)
d- Tacrine
Answer: c
86-Metabolic effects of BB include all of the following except:
a- Decreased glucagon release
b- Decreased glycogenolysis
c- Hypertriglyceridemia
d- Hyperglycemia
Answer: d
87- Ipratropium approved for: Maintaining COPD
88. atropine least S.E : - decrease gastric secretion
89 - Patient with arrhythmia discharged from the hospital which
medication used to
control his condition :- verapamil
90. prinzmetal angina:
a-sudden spasm
b-sudden spasm with atherosclerosis
c-sudden spasm with atherosclerosis and not responsive to CCBs and
nitroglycerin
d- sudden spasm ,with atherosclerosis, and respond to CCBs and
nitroglycerin
Answer: d
91- Xanax ®‫آ‬alprazolam (CDA) must store in:
a. Steel cupboard well closed
b. Cupboard opened by 2 person
answer: a
92. years old Male patient , he is a smoker and he is taking an
antiarrhythmic
medications , which of the following drugs should be avoided :
A. Digoxin
B. Verapamil
C. Amiodrone
D. lidocaine
Answer: b

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