Fact Sheet
SPDR® S&P® XBI Equity
Biotech ETF As of 03/31/2024
Total Return (As of 03/31/2024)
Key Features
NAV Market Value Index
(%) (%) (%)
•• The SPDR® S&P® Biotech ETF seeks to provide investment
Cumulative
results that, before fees and expenses, correspond generally to
the total return performance of the S&P® Biotechnology Select QTD 6.47 6.32 6.47
IndustryTM Index (the “Index”) YTD 6.47 6.32 6.47
•• Seeks to provide exposure to the Biotechnology segment of Annualized
the S&P TMI, which comprises the following sub-industries: 1 Year 24.70 24.49 25.67
Biotechnology
3 Year -11.18 -11.24 -11.00
•• Seeks to track a modified equal weighted index which provides
the potential for unconcentrated industry exposure across 5 Year 1.02 1.00 1.15
large, mid and small cap stocks 10 Year 7.47 7.45 7.39
•• Allows investors to take strategic or tactical positions at a
more targeted level than traditional sector based investing
Gross Expense Ratio (%) 0.35
Net Expense Ratio (%) 0.35
About This Benchmark 30 Day SEC Yield (%) 0.01
Past performance is not a reliable indicator of future performance.
The S&P Biotechnology Select Industry® represents the Investment return and principal value will fluctuate, so you may have a
biotechnology segment of the S&P Total Market Index (“S&P gain or loss when shares are sold. Current performance may be higher
or lower than that quoted. All results are historical and assume the
TMI”). The S&P TMI is designed to track the broad U.S. equity reinvestment of dividends and capital gains. Visit ssga.com for most
market. The biotechnology segment of the S&P TMI comprises recent month-end performance. Performance is shown net of fees.
the Biotechnology sub-industry. The Index is modified Performance of an index is not illustrative of any particular investment. It
is not possible to invest directly in an index. Index returns are unmanaged
equal weighted. and do not reflect the deduction of any fees or expenses. Index returns
reflect all items of income, gain and loss and the reinvestment of dividends
and other income as applicable.
Fund Information
Inception Date 01/31/2006
Characteristics
CUSIP 78464A870
Est. 3-5 Year EPS Growth -9.77%
Index Dividend Yield 0.11%
Price/Earnings Ratio FY1 14.58
Number of Holdings 135
Price/Book Ratio 3.68
Average Market Cap (M) US$11,569.60
Not FDIC Insured. No Bank Guarantee. May Lose Value.
1
Top 10 Holdings Weight (%)
EXACT SCIENCES CORP 1.17
VIKING THERAPEUTICS INC 1.16
CRINETICS PHARMACEUTICALS IN 1.13
EXELIXIS INC 1.09
BRIDGEBIO PHARMA INC 1.09
CYTOKINETICS INC 1.08
DYNE THERAPEUTICS INC 1.08
MADRIGAL PHARMACEUTICALS INC 1.06
SAREPTA THERAPEUTICS INC 1.06
AMGEN INC 1.06
Totals may not equal 100 due to rounding.
ssga.com the calculation. public health issues, or other events could 500 and the 500 are trademarks of Standard
Price/Book Ratio The weighted harmonic have a significant impact on the Fund and its & Poor’s Financial Services LLC (“S&P”); Dow
Information Classification: General average of closing market price divided by investments. Jones® is a registered trademark of Dow Jones
the most recent reported book value for each Equity securities may fluctuate in value and Trademark Holdings LLC (“Dow Jones”) and
security in the fund’s portfolio as calculated for can decline significantly in response to the has been licensed for use by S&P Dow Jones
State Street Global Advisors the last twelve months. activities of individual companies and general Indices; and these trademarks have been
One Iron Street, Boston MA 02210 market and economic conditions. licensed for use by S&P DJI and sublicensed
T: +1 866 787 2257 Funds investing in a single sector may be for certain purposes by State Street Global
Important Risk Information subject to more volatility than funds investing Advisors. The fund is not sponsored, endorsed,
in a diverse group of sectors. sold or promoted by S&P DJI, Dow Jones, S&P,
Weights are as of the date indicated, are Because of their narrow focus, sector their respective affiliates, and none of such
Glossary funds tend to be more volatile than broadly parties make any representation regarding
subject to change, and should not be relied
upon as current thereafter. diversified funds and generally result in greater the advisability of investing in such product(s)
NAV The market value of a mutual fund’s or price fluctuations than the overall market. nor do they have any liability for any errors,
ETFs total assets, minus liabilities, divided by Investing involves risk including the risk of loss
of principal. The Fund is classified as “diversified” under omissions, or interruptions of these indices.
the number of shares outstanding. the Investment Company Act of 1940, as The S&P Select Industry series is designed
Market Value Determined by the midpoint The information provided does not constitute
investment advice and it should not be relied amended (the “1940 Act”); however, the Fund to measure the performance of narrow GICS
between the bid/offer prices as of the closing may become “non-diversified,” as defined (Global Industry Classification Standard)
time of the New York Stock Exchange (typically on as such. It should not be considered a
solicitation to buy or an offer to sell a security. under the 1940 Act, solely as a result of sub-industries. The S&P Biotech Select
4:00PM EST) on business days. tracking the Index (e.g., changes in weightings Industry Index is an equal-weighted index that
Gross Expense Ratio The fund’s total It does not take into account any investor's
particular investment objectives, strategies, of one or more component securities). When draws constituents from the Biotechnology
annual operating expense ratio. It is gross of the Fund is non-diversified, it may invest a segment of the S&P TMI. Liquidity and market
any fee waivers or expense reimbursements. tax status or investment horizon. You should
consult your tax and financial advisor. relatively high percentage of its assets in a capitalization screens are applied to the index
It can be found in the fund’s most recent limited number of issuers. to ensure investability.
prospectus. The whole or any part of this work may not be
reproduced, copied or transmitted or any of Passively managed funds invest by Distributor State Street Global Advisors
30 Day SEC Yield (Also known as sampling the index, holding a range of Funds Distributors, LLC, member FINRA, SIPC,
Standardized Yield) An annualized yield that its contents disclosed to third parties without
SSGA’s express written consent. securities that, in the aggregate, approximates an indirect wholly owned subsidiary of State
is calculated by dividing the net investment the full Index in terms of key risk factors and Street Corporation. References to State Street
income earned by the fund over the most This communication is not intended to be an
investment recommendation or investment other characteristics. This may cause the may include State Street Corporation and its
recent 30-day period by the current maximum fund to experience tracking errors relative to affiliates. Certain State Street affiliates provide
offering price. advice and should not be relied upon as such.
The Fund's investments are subject to performance of the index. services and receive fees from the SPDR ETFs.
Est. 3-5 Year EPS Growth Based on the While the shares of ETFs are tradable on
underlying holdings of the fund. The actual changes in general economic conditions, Before investing, consider the
general market fluctuations and the risks secondary markets, they may not readily
earnings estimates for the underlying holdings trade in all market conditions and may funds’ investment objectives, risks,
are provided by FactSet, First Call, I/B/E/S inherent in investment in securities markets. charges and expenses. To obtain a
Investment markets can be volatile and prices trade at significant discounts in periods of
Consensus, and Reuters and are used to market stress. prospectus or summary prospectus
calculate a mean 3-5 year EPS growth rate of investments can change substantially due
to various factors including, but not limited ETFs trade like stocks, are subject to which contains this and other
estimate. investment risk, fluctuate in market value and
Index Dividend Yield The weighted average to, economic growth or recession, changes information, call 1-866-787-2257 or
in interest rates, changes in the actual or may trade at prices above or below the ETFs
of the underlyings’ indicated annual dividend
perceived creditworthiness of issuers, and net asset value. Brokerage commissions and visit ssga.com. Read it carefully.
divided by price, expressed as a percentage. ETF expenses will reduce returns.
Price/Earnings Ratio FY1 The weighted general market liquidity. The Fund is subject
to the risk that geopolitical events will disrupt Intellectual Property Information: The ©
2024 State Street Corporation.
harmonic average of current share price S&P 500® Index is a product of S&P Dow Jones All Rights Reserved.
divided by the forecasted one year earnings securities markets and adversely affect global
economies and markets. Local, regional or Indices LLC or its affiliates (“S&P DJI”) and Tracking Number: 6033285.1.4.AM.RTL
per share for each security in the fund. have been licensed for use by State Street Expiration Date: 07/31/2024
Negative and positive outliers are included in global events such as war, acts of terrorism,
the spread of infectious illness or other Global Advisors. S&P®, SPDR®, S&P 500®,US ETF-XBI 20240411/14:09
