Biology
(1) Review
Begin the lesson by briefly reviewing key concepts related to DNA, genes,
and chromosomes. Use a mind map on the board to visually connect these
concepts. Ask students to recall previous lessons on heredity and traits,
emphasizing how genetic information is passed from one generation to the
next.
(2) Motivation
Present a short video clip (3-5 minutes) showcasing groundbreaking
applications of genetic engineering, such as genetically modified organisms
(GMOs), gene therapy, and CRISPR technology. After the video, ask students
to share their thoughts on how these advancements might impact society,
health, and the environment.
(3) Activity
Interactive Workshop: Genetic Engineering Simulation
Materials Needed:
Simulation software or online platforms (such as LabXchange or
BioMan Biology)
Worksheets for recording observations
Colored markers and poster boards for group presentations
Instructions:
1. Group Formation: Divide students into small groups of 4-5.
2. Simulation Exploration: Assign each group a specific genetic
engineering process (e.g., CRISPR, recombinant DNA technology,
cloning). Each group will use the simulation software to explore their
assigned process.
3. Data Collection: While exploring, students will fill out a worksheet
that includes:
Key steps involved in the process
Tools and techniques used
Real-life applications of this technology
4. Poster Preparation: After completing the simulation, each group will
create a poster summarizing their findings, including diagrams or
flowcharts to illustrate the process.
5. Presentation: Groups will present their posters to the class,
explaining their assigned process and its significance in genetic
engineering.
(4) Analysis
After presentations, facilitate a class discussion about the similarities and
differences between the processes presented. Use guiding questions such
as:
What are the common steps in genetic engineering techniques?
How do these processes differ in terms of applications and ethical
considerations?
(5) Abstraction
Guide students to abstract the key concepts of genetic engineering
processes. Create a Venn diagram on the board to compare and contrast
different methods. Discuss how these methods can lead to advancements in
medicine, agriculture, and biotechnology.
(6) Application
Real-Life Problem Scenario: Present the following scenario to the
students: "A farmer is struggling with a crop that is susceptible to a certain
pest. Using genetic engineering, how could the farmer modify the crop to
increase its resistance? Discuss the potential benefits and risks involved in
this process." Encourage students to brainstorm solutions, considering both
the technological and ethical implications.
(7) Assessment
Quiz Questions:
1. Multiple Choice: What is the primary goal of genetic engineering?
A) To create new species
B) To modify an organism's DNA
C) To clone organisms
D) To study heredity
Answer: B) To modify an organism's DNA
2. True/False: Genetic engineering can only be used in plants.
Answer: False
3. Fill-in-the-Blank: The technique used to edit genes at specific
locations in the DNA is known as __________.
Answer: CRISPR
4. Multiple Choice: Which of the following is a method of gene transfer?
A) Electroporation
B) Photosynthesis
C) Fermentation
D) Respiration
Answer: A) Electroporation
5. True/False: Cloning is a genetic engineering technique that creates
genetically identical organisms.
Answer: True
(8) Assignment
Homework: Write a one-page essay discussing the potential ethical
implications of genetic engineering in humans. Include at least three
different viewpoints (supporting and opposing) and how these viewpoints
can affect public perception and policy-making in genetic engineering.
Additional Questions and Answers
1. What is genetic engineering?
Answer: Genetic engineering is the direct manipulation of an
organism's DNA to alter its characteristics.
2. Name one application of genetic engineering in medicine.
Answer: Gene therapy, which aims to treat or prevent diseases
by inserting genes into a patient's cells.
3. What is recombinant DNA technology?
Answer: A method that combines DNA from different sources to
produce new genetic combinations.
4. What is the purpose of using a vector in genetic engineering?
Answer: Vectors are used to carry the DNA of interest into the
host cell.
5. Why is CRISPR considered a revolutionary tool in genetic
engineering?
Answer: CRISPR allows for precise editing of DNA, making the
process faster, cheaper, and more accurate than previous
methods.
Interactive Activities
1. DNA Extraction Lab: Students will conduct a simple DNA extraction
using fruits (like strawberries) and common household items (dish
soap, salt, and rubbing alcohol). They will observe the DNA and discuss
its implications in genetic engineering.
2. Debate on GMOs: Organize a class debate where students are
divided into two teams—one supporting GMOs and another opposing
them. Each team will research and present their arguments, fostering
critical thinking about the ethical implications of genetic engineering.
3. Genetic Engineering Role-Play: Assign students different roles
(scientist, ethicist, farmer, consumer) in a mock town hall meeting to
discuss a new genetic engineering project. Each student will prepare a
short speech representing their character's viewpoint, promoting
engagement and understanding of various perspectives in the field of
genetic engineering.
