Central Line-Associated Bloodstream Infections
(CLABSI)
A central line bloodstream infection (CLABSI) occurs when bacteria or other germs
enter the patient’s central line and then enter into their bloodstream. These infections
are serious but can often be successfully treated. Health care workers, patients and
families can play an active role in CLABSI prevention. Most of these infections can be
prevented with the correct insertion, cleaning, and care practice of a central line.
What is this measure?
A central line is a catheter that is placed into a patient’s large vein, usually in the neck,
chest, arms or groin. The central line is often used to draw blood, or to give critically ill
patients fluids and medications more easily. The line can be left in place for several
weeks or months if needed.
Sometimes, bacteria or other germs can enter the patient’s central line and enter their
bloodstream. This can cause an infection. Johns Hopkins Medicine tracks many
different infections, including patients who develop a CLABSI.
Differential Diagnosis
The differential diagnoses for central line-associated bloodstream infections include the
following:
Exit site infections
Phlebitis
Pocket infections
Sepsis
Tunnel infections
Urinary tract infection
