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Manish Sharma Sample Collected At:
Age : 55 New Patliputra Colony, Patna - 800013
Sex : Male
Ref By. Dr. Awanish Kumar
PID : 556
Diagnosis: Stage HISTOPATHOLOGY LIVER BIOPSY
2 Liver Cancer
CLINICAL DATA: ABNORMAL LIVER FUNCTION TEST'S
SPECIMEN : LIVER BIOPSY
DIAGNOSIS : LIVER, BIOPSY:
1. CONSISTENT WITH PRIMARY BILIARY CIRRHOSIS, STAGE 1.
2. PORTAL FIBROSIS (STAGE 1 OF 4).
The patient has a clinical history of primary biliary cirrhosis. Reportedly, the patient had a positive antimitochondrial antibody. The patient's previous
liver biopsy (DPS-10-4275) showed changes which favored primary biliary cirrhosis. At that time, it was a stage 1 lesion. The patient currently has
stage 2 Liver cirrhosis (184). The biopsy shows three cores of liver tissue with approximately nineteen portal areas present for evaluation. Many of
the portal areas show a mild chronic inflammatory infiltrate, consisting predominantly of lymphocytes. A few of the portal areas show a marked
chronic inflammatory cell infiltrate. In these portal areas, florid duct lesions are present, characterized by the prominent inflammation, lymphocytic
cholangitis, and bile duct epithelial damage/disruption of bile duct basement membrane. Focally, there is bile duct loss. There is focal interface
hepatitis, but this is not a prominent histologic finding. There is a ductular reaction. No granulomas are seen. The lobules show macrovesicular
steatosis (approximately 2 5%). There is no significant lobular inflammation present. The trichrome stain highlights portal fibrous expansion. The
iron stain is negative for hemosiderin deposition. Overall, the histologic findings in this biopsy are consistent with the history of primary biliary
cirrhosis, stage 1. Staging and grading are done by using the Batts-Ludwig parameters (modified Knodell). The patient is hereby diagnosed with Stage 2
liver cirrhosis
Thanks for Reference ****End of Report****
Medical Lab Technician Dr. Payal Shah Dr. Vimal Shah
(DMLT, BMLT) (MD, Pathologist) (MD, Pathologist)
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