HORMONAL CO-ORDINATION
Coordination in mammal s is done by both nervous system and hormonal (endocrine) system.
Endocrine system is made of the endocrine glands that secrete different hormones.
Hormone is a chemical substance produced by endocrine glands, carried in the blood and alters
activity of one or more target organs.
ENDOCRINE AND EXOCRINE GLANDS
Endocrine glands are ductless and their secretion directly gets into the blood whereas exocrine
glands have ducts that carry secretion from the glands to the where they have to work.
Examples of endocrine glands are thyroid gland, islets cells of pancreas, adrenal glands, etc
Examples of exocrine glands are salivary glands, pancreas, sweat glands etc
LOCATION OF ENDOCRINE GLANDS IN THE BODY
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ENDOCRINE GLANDS, THEIR HORMONES AND FUNCTIONS OF HORMONES
 ENDOCRINE        HORMONE(S) SECRETED         TARGET ORGAN(S)           FUNCTION OF THE HORMONE
 GLAND
 PITUITARY        1. Growth hormone           All body parts            -Stimulates growth
                  2. Follicle Stimulating     Ovary                     -Stimulates development of the
                  hormone                                               follicle in ovary
                  3. Luteinising Hormone      Ovary                     -Initiates ovulation
                  4. Anti - diuretic          Kidney                    -Makes kidney to re –absorb
                  Hormone                                               more water
                  5.Thyroid Stimulating       Thyroid gland             -Stimulates thyroid gland to
                  Hormone                                               secrete thyroxine
 THYROID          Thyroxine                   All body parts            Regulates metabolic rate
 ADRENAL          Adrenaline                  Heart, lungs, muscles,    Prepares the body for action
                                              eyes
 PANCREAS         1. Insulin                  Liver                     -Stimulates liver cells to
                                                                        convert excess glucose to
                  2. Glucagon                 Liver                     glycogen
                                                                        -Stimulates liver cells to
                                                                        convert glycogen to glucose
 OVARY            1. Progesterone             Uterus                    -Maintains thickness of the
                                                                        lining of the uterus
                  2. Oestrogen                Uterus                    -Initiates thickening of the
                                                                        lining of uterus lining
 TESTICLES        testosterone                Muscles and testicles     Stimulates testicles to produce
                                                                        hormone and produce
                                                                        secondary sexual
                                                                        characteristics
NOTE: Functions of Insulin and Glucagon were covered under digestive system and testosterone,
progesterone and oestrogen were covered under reproduction
FUNCTION OF ADRENALINE
It prepares the body for action. Such action are fighting, fleeing, taking part in competition etc
CONDITIONS UNDER WHICH ADRENALINE IS SECRETED
Below are conditions that lead to secretion of adrenaline:
Fear, just before competition, stress, anxiety, excitement
EFFECTS OF ADRENALINE
       Breathing rate increases and becomes deeper. This increases the rate at which oxygen is
        supplied into the body
       Increases rate of heart beat. This increase delivery of oxygen and nutrients to respiring cells
        and rate of removal of waste products from the cells.
                                                                                                          2
       Stimulates conversion of glycogen into glucose. This provides the respiring cells with
        glucose.
       Increases the uptake of glucose by cells. This increases the rate of breathing.
COMPARISON OF NERVOUS AND ENDOCRINE SYSTEM
 FEATURE                            NERVOUS SYSTEM                     ENDOCRINE SYSTEM
 Type of message                    Electrical impulses                Chemicals called hormones
 Pathway                            neurones                           blood
 Speed of transmission              Very fast                          slow
 Duration of response               Short lived                        Long lived
 Type of response                   Both voluntary and involuntary     All involuntary
 Target organs                      specific                           widespread
NEGATIVE FEEDBACK
This refers to a response that counteract the effect which produced the response that was occurring.
Eg. When it is cold, impulses are sent to skin to cause vasoconstriction, shivering, erection of hair so
that the body temperature is adjusted to normal level. After the body temperature, if it is increased
above normal level, other impulses are sent to the skin to cause vasodilation, more sweating, hair
lying on skin
Eg 2. Pituitary gland secrete ADH so that it stimulate kidney to reabsorb more water, if the blood
become too dilute, secretion of ADH stop so that concentration of blood can be normal