Introduction
The moral conduct of research including human beings is essential, necessitating that
researchers prioritize protecting participants through informed consent, risk reduction, and
compliance with recognized ethical norms, such as those delineated in the Belmont Report. This
analysis evaluates critical aspects of the supplied movies, emphasizing their importance in
protecting research participants.
Key Points and Rationales
"Caring Corrupted: The Killing Nurses of the Third Reich"
Crucial Observation: The capacity for even well-meaning persons to engage in
detrimental research procedures when influenced by authoritative figures or driven by a
misapplied sense of obligation. This historical incident illustrates the essential requirement for
stringent ethical monitoring and personal accountability in research, particularly for vulnerable
populations.
"Research Ethics Involving Human Subjects"
Honoring their privacy and maintaining the confidentiality of their personal information,
acknowledging their right to reconsider, determine that the research does not align with their
interests, and withdraw without incurring any penalties. Participant risks must be mitigated, and
any study-related dangers should be justifiable concerning the study's benefits. The IRB
mandates that each participant furnish their informed permission.
"The Belmont Report (Part One: Basic Ethical Principles)"
Three fundamental concepts, widely recognized in our cultural tradition, are especially
pertinent to the morality of research including human subjects: the principles of respect for
persons, beneficence, and fairness. This is a significant issue addressed in the movie, as it will
act as a reminder for researchers and as essential knowledge for those involved in the
investigation and their families.
"The Belmont Report (Part Two: Applying the Principles)"
In human subject research, mitigate harms and risks while enhancing benefits; uphold
human dignity, privacy, and autonomy; implement additional safeguards for vulnerable groups;
and endeavor to equitably allocate the rewards and burdens of research. The discussion of risk
and benefit pertains to the ratio of risk, indicating that a substantial advantage should outweigh a
significantly greater risk to the subject.
"Guiding Principles of Institutional Review Boards (IRB)"
All human subjects research activities governed by HHS regulations require review by an
Institutional Review Board (IRB). Non-exempt research is subject to either Expedited
(subcommittee) review or Full Board review. Protocols cannot be accelerated if the research
entails more than minimum risk. Deliberation over the objectives of the research, particularly
concerning its participants, is the initial stage toward a productive experiment.
Conclusion
Comprehending the historical context of inappropriate research procedures and the
fundamental principles delineated in the Belmont Report is essential for researchers to prioritize
the safeguarding of human subjects. By maintaining informed consent, reducing risks, and
addressing potential vulnerabilities, researchers can perform ethical research that serves societal
interests while protecting the rights and welfare of participants.
References
Daigle, D. (2014). Research Ethics Involving Human Subjects [Video]. YouTube. Located at:
https://www.youtube.com/watch?v=-O5gsF5oyls
IRBMed. (2012). The Belmont Report (Part One: Basic Ethical Principles) [Video]. YouTube.
Located at: https://youtu.be/86zWBjDaXPk
IRBMed. (2012). The Belmont Report (Part Two: Applying the Principles) [Video]. YouTube.
Located at: https://youtu.be/cIafASIIU70
Johns Hopkins Medicine. (2016). Guiding Principles of Institutional Review Boards (IRB)
[Video]. YouTube. Located at: https://www.youtube.com/watch?v=iFik0of3iUM
UTHealth Nursing. (2017). Caring Corrupted: The Killing Nurses of the Third Reich [Video].
YouTube. Located at: https://youtu.be/Rz8ge4aw8Ws
