DRUG STUDY

Name of Drug Dosage/Frequenc Mechanism of Indication Contraindication Adverse Effect Nursing Responsibilities
y/ Action
Timing/Route

Generic Name: Dosage: Co-trimoxazole is - Treatment of - Patients with Integumentary: ● Obtain history for
800 mg/1 capsule an antibiotic made travelers’ diarrhea known - Rash, fever, hypersensitivity
Cotrimoxazole up of two different caused by hypersensitivity to pallor, purpura, to trimethoprim or
antibiotics susceptible sulfonamides or any sulfonamide,
Frequency: (sulfamethoxazole enterotoxigenic trimethoprim Respiratory: sulfite sensitivity.
BID and trimethoprim). Escherichia coli. - sore throat, ● Monitor daily
Brand Name: - Patients with a cough, and pattern of bowel
Timing: history of shortness of breath activity, stool
Bactrim 8am - 8pm Sulfamethizole - Treatment of drug-induced may be early signs consistency.
works by enteritis caused by immune of serious adverse ● Monitor renal,
Route: interfering with susceptible thrombocytopenia effects. hepatic, and
PO bacterial folic acid Shigella flexneri or with sulfonamides hematology
Classifications: synthesis and S. sonnei or trimethoprim. function.
growth. On the ● Monitor input and
Sulfonamides other hand, output.
- Antiprotozoal Trimethoprim ● Monitor vital
Agents (Antibiotic) works by inhibiting signs every 4
dihydrofolic acid hours.
reduction. As a ● Educate the
result, the patient that they
medication acts as may take
a bactericidal co-trimoxazole
agent in with a meal or a
susceptible snack to reduce
microorganisms. side effects.
● Instruct the
patient or
Reference: guardian to
Kizior, R., & continue
Hodgson, K. medication for
(2021). Saunders the full length of
Nursing Drug therapy.
Handbook 2021. ● Advise patient to
Elsevier. take oral doses
with 8 oz water
and drink several
extra glasses of
water daily.
● Instruct the
patient to report
immediately any
new symptoms,
especially rash,
other skin
changes,
bleeding/bruising,
fever, sore throat,
and diarrhea.
● Encourage the
patient to avoid
prolonged
exposure to UV,
and direct
sunlight because
the medication
makes them
more sensitive to
sunlight.
 Name of Drug Dosage/Frequenc Mechanism of Indication Contraindication Adverse Effect Nursing Responsibilities
y/ Action
Timing/Route

Generic Name: Dosage: Metoclopramide - Treatment of - Patients with - Extrapyramidal ● Instruct patient to
10mg/ 1 tablet causes antiemetic nausea and hypersensitivity to reactions occur avoid tasks that
Metoclopramide effects by inhibiting vomiting in patients metoclopramide. mostly in young require alertness,
Frequency: dopamine D2 and with adults (18–30 yrs) and motor skills
Q8hrs for 2 days serotonin 5-HT3 gastroesophageal receiving large until response to
then PRN receptors in the reflux doses (2 mg/kg) drug is
Brand Name: chemoreceptor established.
Timing: trigger zone (CTZ) - Akathisia ● Advise patient to
Reglan 8am, 4pm, 12am located in the area (involuntary limb avoid alcohol to
postrema of the movement, facial prevent adverse
Route: brain. This action grimacing, motor effects.
PO interferes with the restlessness). ● Monitor for
Classifications: central anxiety,
mechanisms that - Neuroleptic restlessness,
Antiemetic create the malignant extrapyramidal
sensation of syndrome symptoms (EPS)
nausea and also (diaphoresis, fever, during IV
stimulates lower unstable B/P, administration.
oesophageal muscular rigidity). ● Monitor daily
sphincter pattern of bowel
contraction and activity, stool
gastric motility. As consistency.
a result, it ● Assess skin for
accelerates rash. Evaluate for
intestinal transit, therapeutic re-
promotes gastric sponse from
emptying, and gastroparesis
relieves nausea, (nausea, vomit-
and vomiting. ing, bloating).
● Monitor renal
function
Reference: ● Monitor vital
Kizior, R., & signs every 4
Hodgson, K. hours
(2021). Saunders
Nursing Drug
Handbook 2021.
Elsevier.

Isola, S., Hussain,

A., Dua, A., Singh,
K., & Adams, N.
(2023).
Metoclopramide -
StatPearls - NCBI
Bookshelf.
National Library of
Medicine.
https://www.ncbi.nl
m.nih.gov/books/N
BK519517/
 Name of Drug Dosage / Mechanism of Indication Contraindication Adverse Effect Nursing
Frequency/ Action Responsibilities
Timing / Route

Dosage: Analgesic: - Fever - Severe hepatic Early Signs of - Check the patient’s
Generic Name: Acetaminophen
500mg/tab Activates - Mild to moderate impairment or medical record for
Toxicity:
Paracetamol descending pain severe active liver Anorexia, nausea, allergies.
diaphoresis, fatigue
Frequency: serotonergic disease - - Assess onset, type,
within the first
PRN for fever inhibitory hypersensitivity to 12–24 hrs. location, and duration of
pathways paracetamol or its pain
Brand Name: Later Signs of
Timing: in CNS. components Toxicity: Vomiting, - Assess relief of pain or
Biogesic right upper
As needed for Antipyretic: Inhibit fever
quadrant
fever hs hypothalamic tenderness, - Monitor for adverse
elevated LFTs
heat-regulating effects
within 48–72 hrs
Classification: Route: Center. after ingestion. - Instruct the patient to
PO avoid alcohol
Analgesic
Reference:
(Non-Opioid) -
Kizior, R., &
Antipyretic
Hodgson, K.
(2021).
Saunders Nursing
 Drug Handbook
2021. Elsevier.

Name of Drug Dosage / Mechanism of Indication Contraindication Adverse Effect Nursing

Frequency/ Timing Action Responsibilities
/ Route

Dosage: Omeprazole is a - In relief of - Hypersensitivity - Pancreatitis - Check the patient’s

Generic Name: - Hepatotoxicity
20mg substituted symptoms in to omeprazole, medical record for
Omeprazole - Interstitial
benzimidazole patients with other proton pump Nephritis (rarely) allergies.
- may increase risk
Frequency: gastric epigastric pain or inhibitors. - Evaluate for
of C. difficile
OD antisecretory discomfort with or - Concomitant use infection therapeutic response
Brand Name: agent and is also without heartburn with nelfinavir or (relief of GI symptoms)
Timing: known as proton rilpivirine. - Report headache,
Acifre
8am pump inhibitor onset of black, tarry
(PPI). It blocks the stools, diarrhea, and
Route: final step in abdominal pain
Classification:
PO gastric acid - Instruct to take
Antacids, production by medication before
Antireflux Agents specific inhibition meals
& Antiulcerants of H+/K+ - Do not crush,
adenosine dissolve, or divide
triphosphatase delayed-release forms
(ATPase) enzyme Avoid alcohol.
system present on - Do not eat raw food or
the secretory food that is not cooked
surface of the thoroughly, such as
gastric parietal sushi and soft-boiled
cell, thereby eggs. Meat should be
suppressing cooked until well-done.
gastric acid Do not take
secretion. unpasteurised whole
milk, cheese or fruit
Reference: juices. Spicy food and
Omeprazole carbonated "fizzy"
drinks like soft drinks
(n.d.).
should also be avoided.
MIMS
- Instruct to avoid lying
Philippines. down soon after eating
as this may worsen
https://www
reflux symptoms.
.mims.com/
 philippines/

drug/info/o

meprazole?

mtype=gen

eric

References:

Cunha, J. (2021, August 31). Metoclopramide: Generic, Uses, Side Effects, Dosages, Interaction, Warnings. RxList.

https://www.rxlist.com/metoclopramide/generic-drug.htm

Isola, S., Hussain, A., Dua, A., Singh, K., & Adams, N. (2023, July). Metoclopramide - StatPearls - NCBI Bookshelf. National Library of

Medicine. https://www.ncbi.nlm.nih.gov/books/NBK519517/

Kizior, R., & Hodgson, K. (2021). Saunders Nursing Drug Handbook 2021. Elsevier.

Omeprazole. (n.d.). MIMS Philippines. https://www.mims.com/philippines/drug/info/omeprazole?mtype=generic