ESIC QUESTION PAPER 2015 (PHARMACIST)

(ALLOPATHY)
Q.1) The matrix of blood is known as

[a] Plasma

[b] Serum

[c] RBC and WBC

[d] WBC and platelets

Q.2) The life span of RBC is approximately

[a] Less than 10 days

[b] Between 100-120 days

[c] Between 2-3 months

[d] More than three months

Q.3) The normal level of Hb per 100 ml of blood in women is

[a] 14g

[b] 18 g

[c] 20g

[d] 10 g
Q.4) A rise in blood cholesterol may lead to a deposition of
cholesterol on the walls of blood vessels. This causes the
arteries to lose their elasticity and get stiffened. This is called

[a] Hypertension

[b] Hypotension

[c] Arteriosclerosis

[d] Systolic pressure

Q.5) Amino acids are the product of the digestion of

[a] Protein

[b] fat

[c] Vitamin

[d] Carbohydrate

Q.6) All are true about milk as a diet except

[a] It is low in iron content but rich in calcium, sodium and

potassium

[b] The major carbohydrate is lactose

[c] The chief proteins are caseinogens and lactalbumin

[d] It is rich in vitamin C and D but poor in Vitamin A and
Riboflavin

Q.7) A 68-year-old male has been brought to the emergency

in a state of coma. The patient is a known alcoholic from the
past 10 years. A diagnosis of hepatic encephalopathy has
been made. Which of the following nutrient should be
avoided so as to reduce the ammonia formation in the body

[a] Protein

[b] Carbohydrates

[c] Fats

[d] Minerals and Vitamins

Q.8) The stage in which daughter chromosomes move toward

the poles of the spindle is

[a] Anaphase

[b] Metaphase

[c] Prophase

[d] Telophase

Q.9) Ribosomes helps in

[a] Protein synthesis

[b] Photosynthesis

[c] Lipid synthesis

[d] Respiration

Q.10) The plasma membrane is impermeable to all molecules

except

[a] Glucose

[b] ATP

[c] Urea

[d] K+

Q.11) Labelling, packaging are associated with

[a] Price mix

[b] Product mix

[c] Place mix

[d] Promotion mix

Q.12) Which of the following packaging material protect the

drug content against light

[a] Plastic containers

[b] Amber coloured glass containers

[c] Both

[d] None

Q.13) Which of the following packing is commonly used for

packing of tablet & capsules

[a] Blister pack

[b] Strip pack

[c] Both

[d] None

Q.14) Dissolution of a drug particle is described by

[a] Noyes- Whitney equation

[b] Stock’s equation

[c] Drag’s equation

[d] None

Q.15) If the dose of a drug is inadequate, then it generally

requires the following one, to make up its bulk

[a] Binders
[b] Disintegrants

[c] Lubricants

[d] Diluents

Q.16) Which of the following mixer is a first high shear powder

blender/mixer

[a] Diosna mixer

[b] Littleford lodige mixer

[c] Plow mixer

[d] Gral mixer

Q.17) Which treatment is used for solubility of gelatin

[a] Heat

[b] Formalin

[c] Water

[d] Alcohol-

Q.18) Which of the following one is used as opacifier

[a] TiO2

[b] MgO
[c] Siliactes

[d] All of the above

Q.19) In dissolution test, flask is maintained at

[a] 37° C ±0.5 ºC

[b] 41°C ±1°C

[c] 37° C ± 2 ºC

[d] 40° C ± 1 ºC

Q.20) Which of the following substance is used as muco

adhensive

[a] Acacia

[b] CMC

[c] Burnt sugar

[d] Saccharin

Q.21) Which of the following is a type of Oral dosage form

[a] Aerosol

[b] Nebulizer

[c] Subcutaneous administration

[d] Tablet

Q.22) What do you mean by otic dosage form

[a] Dosage form for the drugs administered through the ears

[b] Dosage form for the drugs administered through the eyes

[c] Dosage form for the drugs administered through the nose

[d] Both for the eyes and the nose

Q.23) Of the following oral liquid formulations which would

be considered as an oropharyngeal formulation

[a] Syrup

[b] Elixir

[c] Mouth wash

[d] Linctus

Q.24) OROS is

[a] Oral osmotic pump

[b] Hydrodynamic balance system

[c] Ocular insert

[d] None
Q.25) Rate limiting step of controlled release system is

[a] Absorption of drug in body

[b] Release of drug from dosage form

[c] Elimination of drug from body

[d] Distribution of drug in body

Q.26) Which one of these is not an antioxidant

[a] Sodium bisulphate

[b] Sodium chloride

[c] Sodium metabisulphite

[d] Sodium sulphite

Q.27) Chemically pyrogens are

[a] Lipopolysaccharides

[b] Proteins

[c] Carbohydrates

[d] Lipoprotein

Q.28) In extemporaneous preparation of a suspension,

levigation is used to

[a] Reduce viscosity

[b] Reduce zeta potential

[c] Reduce particle size

[d] All of the above

Q.29) Wilson disease is due to the excess of

[a] Cu

[b] Zn

[c] Fe

[d] Ca

Q.30) Pellagra is due to the deficiency of

[a] Niacin

[b] Thiamine

[c] Vitamin B12

[d] Vitamin C

Q.31) Match the following

Capsule Size Capacity

(i) 0 (A) 0.10 mL

(ii) 1 (B) 0.15 mL

(iii) 3 (C) 0.30 mL

(iv) 5 (D) 0.55 mL

(E) 0.75 mL

[a] i-E, ii-D, iii-C, iv-B

[b] i-D, ii-A, iii-B, iv-C

[c] i-D, ii-B, iii-A, iv-E

[d] i-E, ii-D, iii-B, iv-C

Q.32) Which one of the following is a retrovirus

[a] Polio virus

[b] Hepatitis B virus

[c] Varicella virus

[d] Human immunodeficiency virus

Q.33) Fatty acids in the body are mostly oxidized by

[a] a-oxidation
[b] β-oxidation

[c] γ-oxidation

[d] All of the above

Q.34) Ergot is produced during

[a] Honeydew stage

[b] Sclerotium stage

[c] Ascopore stage

[d] Sphacelia stage

Q.35) Belladona herbs belongs to the chemical class of

[a] Indole alkaloids

[b] Isoquinoline alkaloids

[c] Tropane alkaloids

[d] Quinazoline alkaloids

Q.36) Which of the following has Oxytocic in action

[a] Ipecac

[b] Ergot

[c] Cinchona
[d] Coca leaves

Q.37) Standards for disinfectant fluids come under

[a] Schedule O

[b] Schedule R

[c] Schedule S

[d] Schedule E

Q.38) One of the following is needed for the cosmetics

manufacture

[a] Form 36

[b] Form 32

[c] Form 20

[d] Form 22

Q.39) Which pharmaceutical products is not included in

schedule C

[a] Toxins

[b] Sera

[c] Antigen
[d] Capsule

Q.40) Blood bank comes under the schedule

[a] B

[b] D

[c] F

[d] G

Q.41) Match the following

Type of mill Principle of action

A- Cutter mill i- Impact

B- Revolving mill ii- Pressure

C- Roller mill iii- Attrition and impact

D- hammer mill iv- Cutting

[a] A-iv, B-iii, C-ii, D-I

[b] A-iv, B-ii, C-iii, D-I

[c] A-iv, B-I, C-iii, D-ii

[d] A-iii, B-iv, C-i, D-ii

Q.42) State pharmacy council should have the following
number of elected members

[a] 6

[b] 5

[c] 9

[d] 7

Q.43) Drug and magic remedies act came into

[a] 1955

[b] 1948

[c] 1985

[d] 1919

Q.44) Grant a licence to manufacture a drug requires

[a] Form 24

[b] Form 25

[c] Form 26

[d] Form 27
Q.45) For parenteral preparation in glass containers,
minimum area required

[a] 250 sq. metres

[b] 400 sq. metres

[c] 500 sq. metres

[d] 150 sq. metres

Q.46) Post marketing surveillance comes under clinical trial

[a] Phase I

[b] Phase II

[c]Phase III

[d] Phase IV

Q.47) Hensen’s disease name of which disease

[a] Tuberculosis

[b] Malaria

[c] Leprosy

[d] Viral disease

Q.48) Vitamin B6 is given with isoniazide prophylacticalcy to
preventing

[a] Rickctisial infection

[b] Nephrotoxicity

[c] Neurotoxicity

[d] Hepatitis

Q.49) Match the following

Average weight of tablet Maximum % of difference allowed

1. <130 mg (i) 5

2. 130-324 mg (ii) 7.5

3. >324 mg (iii) 10

[a] 1-(iii), 2-(ii), 3-(i)

[b] 1-(1), 2-(ii), 3-(iii)

[c] 1-(iii), 2-(1), 3-(ii)

[d] 1-(ii), 2-(iii), 3-(1)

Q-50) Which mill is used to get the free flowing spheroidal

particles
[a] Colloid mill

[b] Attrition mill

[c] Cutter mill

[d] Jaw crusher

ANSWERS:
1: A 2: B 3: A 4: C 5: A 6: D 7: A 8: A 9: A 10: B

11: B 12: C 13: A 14: A 15: D 16: B 17: A 18: A 19: A 20: B

21: D 22: A 23: C 24: A 25: B 26: B 27: A 28: C 29: A 30: A

31: A 32: D 33: B 34: —35: C 36: B 37: A 38: B 39: D 40: C

41: A 42: A 43: A 44: B 45: A 46: D 47: C 48: C 49: A 50: B