IV FLUID RATE & DOSE
CALCULATIONS – (
Pediatric ,
Chemotherapy)
Rushikesh B Raut
Clinical Pharmacist
Kamalnayan Bajaj Hospital
Needs of Dose Calculation
Infant, adult and elderly dose calculation depending on the
weight
Without knowing how to administer and monitor medicines and
intravenous therapy it is not possible to perform this task.
Age and sex also plays a role
Sometimes a doctor is not present at the site when the patient
is in need of a medicine.
Knowing the skill of drug calculation makes a nurse confident
Conversion Factors
Solid Liquid
1 KG =1000gm 1 L=1000 ml
1 KG = 2.2 lb 1 ml = 1 cc
1 lb = 450 gm 1 tsp = 5ml
1 gm = 1000mg 1 tbsp= 15 ml
1 mg = 1000mcg 1 ml = 15 drops
Length Time
12 '' = 1 Foot 1 Hour = 60 minutes
1Inch = 2.5 cm 1 Min = 60 Seconds
1 KM = 1000m
1 M = 100 cm Temperature
1 M = 1000mm 0 F= (00 C x 1.8)+ 32
1 M = 3.3 Ft 0 C= (0 F - 32 ) x 1.8
Drop Factor
1 ml = 15 Drops = 60 Microdrops
Macroset = 15 drops
Microset = 60 drops
BT Set = 10 drops
Flow rate
Flow rate = Volume = ml
Time Hr
Drip rate = Flow rate x Drop factor = drops
60 min
1. Calculate the IV flow rate & drip rate for 1000 mL of NS to be infused
in 9 hours The infusion set is calibrated for a drop factor of 15.
2. Calculate the IV flow rate & drip rate for 250 mL of 0.9% NaCl IV over
3 HOURS .Infusion set has drop factor of 60
Examples
3. Calculate the IV flow rate & drip rate for PCV of 350
mL of over 3.5 HOURS
4. Give 750 ml of Normal Saline over 4 hours with micro
drip . Calculate IV flow rate & drip rate
5. Give 250 ml of packed red cells IV within 4 hours.
Calculate IV flow rate & drip rate
Tips for Correct Calculations:
If necessary, convert between units.
All measurements are in the same units.
In most cases, it is best to convert a larger unit to smaller units
Always check for reasonableness of your answer.
When solving dosage problems for drugs supplied in tablets or
capsules, the quantity, Q, is always 1 because the supply dosage
is per tablet or per capsule
Dose
Dose = Desired dose x Volume/qty
Dose in Hand
1. Consultant writes an order for inj pipzo 300 mg iv to patient of age 2 yrs
Pharmacy dispenses 1 vial of 1.125 gm. Dilute with 5 ml.
2. Advised dose for inj Augmentin is 125 mg. you are having 600 MG in 1 vial.
3. MD writes an order of calcium gluconate 2 gm .Dose in hand is 1375 mg in 10
ml.
4. Pediatric Patient with Allergic fever is ordered Inj Paracetemol 50 mg .Dose in
hand is of 2 ml which contains 300 mg.
5. The Oncologist ordered Inj Oxaliplatin 55 mg. Each 12ml contains 100 mg.
6. Nephrologist ordered tab Arkamin 0.15mg. dose in hand is 100 mcg.
calculate dose to be administered.
Examples
7. A solution of Ferric carboxy maltose inj. Was supposed to administer to
pateint, but the solution was very much viscous, so the Consultant ordered
to decrese the concentration to 1 mg/ ml. How will you manage?
8. Inj. Amikacin is order to pediatric patient with wt 2.5 kg . Ordered dose
is 15mg/kg. How much ml will you administer to patient if Amikacin 500
mg is available in 2 ml.
9. Inj. Meropenem is order to pediatric patient with wt 3.5 kg . Ordered
dose is 25mg/kg. How much ml will you administer to patient if
Meropenem 500 mg in powder form.
Syringe Pump
1.Consultant Ordered Inj. Streptokinase 2.5 Lakh unit stat dose.
Followed by 1 lakh units / hour, via syringe pump.How many ml will
you administer. ( Dose Available- 15,00,000 IU )
2. Consultant Ordered Inj. Polymixin B 1 Lakh unit stat dose.
Followed by 50, 000 units / hour, via syringe pump. How many ml
will you administer. ( Dose Available- 5,00,000 IU )
If consultant ordred inj N.Acetyl cystine to 65 kg patient as Inj acetyl cystiene
125 mg /kg f/b acetyl cystiene 100 mg /kg f/b acetyl cystiene 50 mg
/kg How many ampoule you will administer to patient.
Body Surface area
BSA = √Ht in cm x Wt in Kg
3600
1. Calculate BSA for a patient with Ht 1.75 m ft & 85 kg wt.
2. What is BSA for a patient with Ht 170 CM & 90 KG wt.
3. Calculate BSA of patient with weight 26 kg & height 75 cm.
Body Mass Index
BMI = Wt in Kg
(Ht in m)2
1. Calculate BMI of a person who is 174 cm height and
weighs 78 kg.
2. Calculate BMI of a person who is 169 cm and weighs 73
kg
3. Calculate BMI of a person who is 1.4 meters and weighs
64 kg.
Pediatric Doses
Clark rule
It uses Child's Wt
Who are less than 1 years of age
Wt in Pounds & never in Kg
Child's Dose = Avrg Adult dose x (child'wt in pounds)
( 150 lb )
1. Calculate dose for Cisplatin ( adult dose is 60 mg ) for a
patient whose wt is 4.5 kg .
2. Calculate dose for Paclitaxel ( adult dose is 260 mg ) for a
patient whose wt is 10.6 pounds .
3. Calculate dose for Ceftriaxone ( adult dose is 1000 mg) for a
patient whose wt is 6.8 kg .
Fried's rule
• Who are less than 2 years of age
• It uses age in months
Child's Dose = Average Adult dose x (Child's age In months )
150
1. Calculate dose for OXALIPLATIN ( adult dose is 80
mg ) for a patient whose age is 15 months.
2. Calculate dose for Paclitaxel ( adult dose is 260 mg )
for a patient whose age is 18 months.
3. Calculate dose for Ceftriaxone ( adult dose is 1000
mg) for a patient whose age is 8 months
Young's rule
Children with 2 or more years
Child's Dose = Avrge Adult dose x child age in years
childs age in years +12
1. Calculate dose for DOXORUBICIN ( adult dose is 80 mg )
for a patient whose AGE is 3.5 years.
2. Calculate dose for Rituximab ( adult dose is 480 mg ) for a
patient whose AGE is 2.8 years.
3. Calculate dose for Etoposide ( adult dose is 100 mg) for a
patient whose AGE is 2.3 years.
