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Dalia Banks, MD, FASE
Clinical Professor
Division Chief of Cardiothoracic Anesthesiology
Director of Cardiothoracic Anesthesiology Fellowship
Clinical Director of Sulpizio CVC and PTU
University of California San Diego
San Diego, California
Paul G. Barash, MD
Professor Emeritus and Past Chair
Department of Anesthesiology
Yale University School of Medicine
Honorary Attending Anesthesiologist
Yale-New Haven Hospital
New Haven, Connecticut
John F. Bebawy, MD
Associate Professor of Anesthesiology & Neurological Surgery
Northwestern University
Feinberg School of Medicine
Chicago, Illinois
Honorio T. Benzon, MD
Professor of Anesthesiology
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Marcelle E. Blessing, MD
Assistant Professor of Anesthesiology
Yale University School of Medicine
New Haven, Connecticut
Michelle Y. Braunfeld, MD
Professor and Vice Chair
8
Department of Anesthesiology
David Geffen School of Medicine at UCLA
Chair, Department of Anesthesiology
Greater Los Angeles VA Hospital
Los Angeles, CA
Ferne R. Braveman, MD
Vice-Chair for Clinical Affairs
Director of Division of Obstetrical Anesthesiology
Professor of Anesthesiology and Obstetrics, Gynecology and Reproductive
Medicine
Department of Anesthesiology
Yale School of Medicine
New Haven, Connecticut
Brenda A. Bucklin, MD
Professor of Anesthesiology
University of Colorado School of Medicine
Aurora, Colorado
Michael K. Cahalan, MD
Professor and Chair
Department of Anesthesiology
The University of Utah School of Medicine
Salt Lake City, Utah
Levon M. Capan, MD
Professor of Clinical Anesthesiology
New York University School of Medicine
Associate Director of Anesthesia Service
Bellevue Hospital Center
New York, New York
Louanne M. Carabini, MD
Assistant Professor
Department of Anesthesiology
9
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Edmond Cohen, MD
Professor of Anesthesiology and Thoracic Surgery
Director of Thoracic Anesthesia
Icahn School of Medicine at Mount Sinai
New York, New York
Christopher M. Conley, MD
Clinical Assistant Professor of Anesthesiology
Boston University School of Medicine
Boston, Massachusetts
10
Pasadena, California
Professor of Anesthesiology
Keck USC School of Medicine
Los Angeles, California
Visiting Associate
Medical Engineering
California Institute of Technology
Pasadena, California
Bruce F. Cullen, MD
Emeritus Professor
Department of Anesthesiology and Pain Medicine
University of Washington School of Medicine
Seattle, Washington
Rossemary De La Cruz, MD
Academic, Media, and Risk Management Associate
Department of Anesthesiology
Boston Medical Center
Boston, Massachusetts
Steven Deem, MD
Director, Neurocritical Care
Swedish Medical Center
Physicians Anesthesia Service
Clinical Professor of Anesthesiology
University of Washington
Seattle, Washington
Stephen F. Dierdorf, MD
Professor of Clinical Anesthesia
Department of Anesthesia and Perioperative Medicine
Medical University of South Carolina
Charleston, South Carolina
11
University of Washington School of Medicine
Seattle, Washington
Jan Ehrenwerth, MD
Professor Emeritus
Department of Anesthesiology
Yale University School of Medicine
New Haven, Connecticut
John H. Eichhorn, MD
Professor of Anesthesiology
College of Medicine
Provost’s Distinguished Service Professor
Department of Anesthesiology
University of Kentucky Medical Center
Lexington, Kentucky
James B. Eisenkraft, MD
Professor
Department of Anesthesiology
Icahn School of Medicine at Mount Sinai
New York, New York
Alex S. Evers, MD
Henry S. Mallinckrodt Professor and Head
Department of Anesthesiology
Professor of Developmental Biology and Internal Medicine
Washington University School of Medicine
St. Louis, Missouri
Lynne R. Ferrari, MD
12
Chief, Perioperative Anesthesia
Medical Director, Operating Rooms and Perioperative Programs
Department of Anesthesiology, Perioperative and Pain Medicine
Boston Children’s Hospital
Boston, Massachusetts
Scott M. Fishman, MD
Professor, Department of Anesthesiology and Pain Medicine
Chief, Division of Pain Medicine
Vice-Chair, Department of Anesthesiology and Pain Medicine
Director, Center for Advancing Pain Relief
University of California Davis School of Medicine
Sacramento, California
J. Sean Funston, MD
Professor
Department of Anesthesiology
The University of Texas Medical Branch
Galveston, Texas
Steven I. Gayer, MD
Professor of Anesthesiology
University of Miami Health System
Miami, Florida
Sofia Geralemou, MD
Department of Anesthesiology
Stony Brook University Hospital
Stony Brook, New York
Loreta Grecu, MD
13
Clinical Associate Professor of Anesthesiology
Stony Brook University School of Medicine
Stony Brook, New York
Dhanesh K. Gupta, MD
Professor of Anesthesiology
Chief of Neuroanesthesiology
Department of Anesthesiology
Duke University Medical Center
Durham, North Carolina
Carin A. Hagberg, MD
Joseph C. Gabel Professor and Chair
Department of Anesthesiology
UTHealth Medical School
Houston, Texas
Matthew R. Hallman, MD
Assistant Professor
Department of Anesthesiology and Pain Medicine
University of Washington School of Medicine
Seattle, Washington
Kylene E. Halloran, MD
Assistant Professor of Anesthesiology
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire
Stephen C. Haskins, MD
Assistant Anesthesiologist
Hospital for Special Surgery
Clinical Assistant Professor of Anesthesiology
Weill Cornell Medical College
New York, New York
Tara M. Hata, MD
14
Clinical Assistant Professor
Department of Pediatric Anesthesia
Cleveland Clinic
Cleveland, Ohio
Laurence M. Hausman, MD
Professor of Anesthesiology
Vice-Chair, Academic Affiliations
Director, Ambulatory Anesthesia
Department of Anesthesiology
Perioperative and Pain Medicine
Icahn School of Medicine at Mount Sinai
New York, New York
Christopher L. Heine, MD
Assistant Professor
Department of Anesthesia and Perioperative Medicine
Medical University of South Carolina
Charleston, South Carolina
Thomas K. Henthorn, MD
Professor, Anesthesiology
Department of Anesthesiology
University of Colorado
Aurora, Colorado
15
Department of Anesthesiology
Yale University School of Medicine
Medical Director
Ambulatory Procedures Unit
VA Connecticut Healthcare System
West Haven, Connecticut
Harriet W. Hopf, MD
Professor and Vice-Chair
Department of Anesthesiology
University of Utah School of Medicine
Salt Lake City, Utah
Adam K. Jacob, MD
Associate Professor of Anesthesiology
Mayo Clinic College of Medicine
Rochester, Minnesota
Farid Jadbabaie, MD
Associate Professor of Medicine (Cardiology)
Director of Echocardiography Laboratory
VA Connecticut Healthcare System
Yale School of Medicine
New Haven, Connecticut
Rebecca L. Johnson, MD
Assistant Professor of Anesthesiology
Department of Anesthesiology
Mayo Clinic College of Medicine
16
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Rochester, Minnesota
Sharma E. Joseph, MD
Instructor of Anesthesia
Boston University School of Medicine
Boston Medical Center
Boston, Massachusetts
Jonathan D. Katz, MD
Clinical Professor of Anesthesiology
Yale University School of Medicine
Professor of Anesthesiology
Frank H. Netter MD School of Medicine at Quinnipiac University
Attending Anesthesiologist
St. Vincent’s Medical Center
Bridgeport, Connecticut
Christopher D. Kent, MD
Associate Professor
Department of Anesthesiology and Pain Medicine
University of Washington
Seattle, Washington
Sandra L. Kopp, MD
Associate Professor of Anesthesiology
Department of Anesthesiology
Mayo Clinic College of Medicine
Rochester, Minnesota
Catherine Kuhn, MD
Director & Associate Dean, Graduate Medical Education
Designated Institutional Official
Professor of Anesthesiology
Department of Anesthesiology
Duke University
Durham, North Carolina
17
Jerrold Lerman, MD, FRCPC, FANZCA
Clinical Professor of Anesthesiology
Women and Children’s Hospital of Buffalo
State University of New York
Buffalo, New York
J. Lance Lichtor, MD
Department of Anesthesiology
Yale University School of Medicine
New Haven, Connecticut
Spencer S. Liu, MD
Clinical Professor of Anesthesiology
Weill College of Medicine at Cornell University
Department of Anesthesiology
Hospital for Special Surgery
New York, New York
18
Children’s Healthcare of Atlanta at Henrietta Egleston Hospital for Children
Atlanta, Georgia
Peter Mancini, MD
Assistant Clinical Professor
Department of Anesthesiology
Yale University School of Medicine
New Haven, CT
Aaron J. Mancuso, MD
Assistant Professor of Anesthesiology
Geisel School of Medicine
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire
Gerard Manecke, MD
Chair, Department of Anesthesiology
UCSD Medical Center
San Diego, California
Melissa M. Masaracchia, MD
Assistant Professor of Anesthesiology
Dartmouth-Hitchcock Medical Center
Geisel School of Medicine
Lebanon, New Hampshire
19
Accreditation Council for Graduate Medical Education
Department of Institutional Accreditation
Chicago, Illinois
Sanford M. Miller, MD
Clinical Professor (Emeritus) of Anesthesiology
NYU School of Medicine
Former Assistant Director of Anesthesiology
Bellevue Hospital Center
New York, New York
Sawyer A. Naze, MD
Resident
Department of Anesthesiology
Feinberg School of Medicine
20
Northwestern University
Chicago, Illinois
Steven M. Neustein, MD
Professor of Anesthesiology
Icahn School of Medicine at Mount Sinai
New York, New York
Mark C. Norris, MD
Director of Obstetric Anesthesia
Boston Medical Center
Clinical Professor of Anesthesiology
Boston University School of Medicine
Boston, Massachusetts
Rafael Ortega, MD
Professor
Vice-Chairman of Academic Affairs
Department of Anesthesiology
Boston University School of Medicine
Boston, Massachusetts
21
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gastric tetany. The question of diagnosis can usually be settled by
having the patient swallow the dissolved separate parts of a Seidlitz
powder, one after the other, when the carbon dioxide released within
the stomach will cause it to balloon up and assume that shape and
position which the amount of its dilatation permits.
Gastric dilatation which does not quickly yield to lavage and
suitable medication is of itself always an indication for operation.
When accompanied by a tumor, especially if this move and change
position with the stomach, a cancerous condition may be assumed,
which, while not permitting a cure, may nevertheless be ameliorated
by a gastro-enterostomy. In the absence of actual cancerous
conditions the surgical treatment of chronic dilatation is exceedingly
satisfactory.
This surgical treatment consists in the application of one at least of
the following expedients:
1. Local relief of mechanical pyloric obstruction, as by any one
of the pyloroplastic methods;
2. Gastroplication, by which the capacity of the stomach is
materially reduced;
3. Gastro-enterostomy, by which mechanical obstruction is
atoned for by a free outlet, provided at a point where gravity
as well as peristalsis shall assist in completely emptying the
viscus.
The methods in vogue a few years ago for opening the stomach
and merely stretching the pyloric outlet have been supplanted by
other plastic operations which have proved more satisfactory
because of the greater permanency of their results.
GASTROPTOSIS.
The downward displacement of the stomach, to which the term
gastroptosis has been given, implies not only more or less actual
dilatation, but also a stretching or lengthening of the upper
attachments and peritoneal folds which should hold the stomach up
in place. When these yield and the stomach is thus permitted to
drop, more or less obstruction of the pylorus and kinking of the
duodenum are apt to occur. The condition regarded surgically is not
essentially different from that of chronic dilatation. When the
stomach is distended with carbon dioxide its normal position may be
easily recognized, while, at the same time, it is determined that it is
perhaps but little dilated.
The causes which lead to this condition, aside from those which
affect the stomach proper, include tight lacing, by which the
supporting viscera are forced downward and the stomach permitted
to fall with them. In addition to such a cause any previous disease by
which the abdominal viscera have been affected or ligaments
weakened would be of more or less effect. The condition leads
sooner or later to one of dilatation, and always merges into it. Its
symptoms are those of dilatation, only in milder degree. On account
of the dragging upon the upper supports patients frequently complain
of intense lumbago, and they nearly always become neurasthenic.
Treatment.—The ordinary routine treatment failing to give relief,
one may, in mild cases, adopt an external mechanical
treatment, consisting of a suitable abdominal bandage which should
press the viscera up from beneath, and thus relieve splanchnic
congestion and weight.
Mechanical support failing and symptoms persisting, the surgeon
is able to afford relief by gastropexy, first suggested by Duret, and
consisting of an exposure of the stomach through the middle line and
its fixation to the anterior abdominal wall. This, however, has its
theoretical disadvantages, since it might be followed by symptoms
similar to those resulting from pathological adhesions. The method
has been more or less modified, sutures being passed through the
gastrohepatic omentum and gastrophrenic ligament in such a way as
to bring them into close contact and looking to their complete union.
Thus, Beyer, of Philadelphia, has reported four cases apparently
successfully operated upon in this fashion. Bier has added four
others, all of which seem to afford much encouragement to operative
treatment of gastroptosis. Furthermore, Coffey has modified the
technique in such a way as to include a sort of suspension of the
stomach by making a hammock out of the great omentum. He did
this by stitching the omentum to the abdominal peritoneum, about
one inch above the umbilicus, with a transverse row of sutures about
one inch apart.
GASTRIC TETANY.
Gastric tetany has but relatively small interest for the surgeon,
save as it may complicate some of his results or prevent his
endeavor to secure them. The condition is usually characterized by
peculiar, disturbed sensation in the extremities, with a feeling of
coldness or numbness in the limbs, and drowsiness, vertigo, and
disproportionate weakness after exercise. Somewhat severe attacks
are sometimes precipitated by lavage, and are then begun with a
complaint of formication, followed by tetanic contraction of the
muscles of the extremities. Instead of tonic spasm the muscles may
be in more or less constant motion. The muscles of the face, neck,
and abdomen are also involved. The facial expression changes, and
patients may complain of loss of vision. During these paroxysms
they may even mutter or speak unintelligibly. Chvostek some time
ago showed how to produce these spasms, when the condition is
present, by tapping over the facial nerve just at its exit from the
cranium, and Trousseau demonstrated that during the attack the
paroxysms may be produced at will by compressing the affected
parts in such a way as to impede venous or arterial circulation
through them. Some of these spasmodic attacks are accompanied
by severe pain, while spasm is usually made less painful by gently
yet forcibly overcoming it by pressure. The condition is essentially
toxic, usually autotoxic, and yet, inasmuch as it may complicate the
best efforts of the surgeon or complicate the case upon which he
would wish to operate, it is deserving of this brief description here,
largely in order that it may not be mistaken for true tetanus or be
misinterpreted in any other way.
CARDIOSPASM.
This is a term recently suggested by Mikulicz for a peculiar
contraction of the lower end of the esophagus and the cardiac orifice
of the stomach, which is occasionally met with, and until fully
described by him was somewhat misunderstood. In consequence of
the spasmodic stricture thus produced there occurs dilatation of the
esophagus above and formation of a sac, which may be discovered
by the bougie or tube, or by a good radiogram, after having been
filled with a weak bismuth emulsion. Such sacculation had always
been previously regarded as due to esophageal diverticulum, which
it greatly simulates at first and in time practically becomes. It is due
either to primary and unexplained spasm of the muscular coat at this
level, or to a primary atony for the esophageal muscle above the
stricture. It has been ascribed also to paralysis of the circular fibers
and spasm of the cardia, due to vagus involvement and to primary
esophagitis. The view that it is of congenital origin can scarcely be
sustained.
Symptoms.—The symptoms and signs produced are not widely
different from those of a capacious diverticulum. It is
difficult, often impossible, to pass a stomach tube into the stomach, it
being diverted into the upper cavity. The patient moreover, vomits
material which is undigested and more or less putrefactive, and, at
the same time, without evidences of actual stomach disease. Such a
sac may hold even two pints, and thus it will be seen how much
material may be vomited or washed out by lavage which, at the
same time, never entered the stomach. Should it be possible to enter
the stomach the two sets of contents will be found quite different.
Treatment.—While more or less benefit and relief may be
obtained from frequent washing of the abdominal sac
thus produced the real cure will only come, as shown by Mikulicz,
from opening of the stomach and dilatation of its constricted upper
orifice.
PYLORIC STENOSIS.
Reduction in caliber of the pyloric opening, amounting in extreme
cases to absolute closure, may be met with at various ages and
following various conditions.
A congenital stenosis has been observed, although very
infrequently.[54]
[54] Fiske (Annals of Surgery, July, 1906) states that there are at
present on record 121 cases of hypertrophic stenosis of the pylorus in
infants. The three theories advanced to account for the condition as
occurring before birth presuppose either a true malformation with muscular
hypertrophy, a secondary hypertrophy due to prenatal pyloric spasm, or a
spastic condition of the pyloric region without definite gross anatomical
lesion. None of these theories satisfies the condition in any but a small
proportion of cases, although either of them doubtless is or may be correct
in certain instances; 71 of these cases have now been operated upon, of
which 33 died, gastro-enterostomy giving 57 per cent. of recoveries and
pyloroplasty 54 percent.
GASTRIC ULCER.
During the past few years the studies of internists, of pathologists,
and of surgeons have all served to show that gastric ulcer in any
form is a more common lesion than was suspected by the previous
generation. At first it nearly always comes under the care of the
internist, but too often, becoming chronic, it is too long continued
under his care until a serious, perhaps almost fatal, hemorrhage
makes operative relief more dangerous, if not impossible, or until a
chronic ulcer has degenerated into a cancer, and this is permitted to
go on until the patient pays with his life the penalty for such
inattention.
Ulcers in the gastric mucosa vary from a simple fissure (such as
may be seen in the mucosa of the lip or the anus) to extensive and
deep ulcerations, which weaken the stomach structure in spite of
protective infiltration and even adhesions, until a final perforation
may terminate the case, either by hemorrhage or septic peritonitis.
While surgical teaching has of late pointed more and more definitely
to the importance of ulcers resulting from simple erosions, or
apparently mere abrasions which have not been appreciated, most
pathologists and surgeons fail to realize that even from so trifling a
surface alarming hemorrhages may occur. Such lesions appear upon
the postmortem table to be minute and unimportant, but, occurring
during life, they have an importance of their own.
Gastric ulcers, then, should be referred to as erosions, as simple
or complicated ulcers, and as ulcerating cancers, in addition to which
there may be mentioned the rare lesions produced by tuberculosis
and syphilis. These ulcers are always to be regarded seriously,
because in their milder expressions they cause pain and various
forms of dyspepsia and indigestion, while their more serious
consequences include hemorrhage, which may be fatal, and
perforation, which is essentially so unless surgical intervention be
prompt and complete.
Symptoms.—The symptoms and discomforts which they produce
include pain, which is nearly always most pronounced
within a short time after the ingestion of food, and which may be
accompanied by local tenderness more or less constant. As the case
progresses, with the pain usually comes vomiting, by which the
former is relieved, the vomitus nearly always containing excess of
hydrochloric acid and sometimes fresh or old blood. The pain of
gastric ulcer is usually referred to the back. The indigestion and the
frequent vomiting together are sufficient to produce a well-marked
anemia, which is more pronounced when much blood is lost. Blood
may not be vomited but escape into the duodenum, and will then
give to the stools a tarry character, which should always be looked
for and identified when discovered. The greater the loss of blood in
either direction the more pronounced will be the anemia. Pain,
vomiting, and evidence of loss of blood constitute the most
distinctive features of gastric ulcer. When these are accompanied by
tenderness in the epigastrium, and by pain in the back, the diagnosis
is almost complete. In the more chronic cases there may have
already occurred contraction of the pylorus and consequent
dilatation of the stomach. Thus symptoms of the latter may be added
to those of the previous condition.[55]
[55] In doubtful cases accompanied by pain it will sometimes be of
value to try the effect of orthoform in ¹⁄₂ Gm. doses, to see if it will relieve it.
This remedy will not anesthetize nerve endings which are protected by skin
or mucous membrane. The fact, then, that it affords relief implies an
ulcerated or exposed area.
The two ever-present and alarming dangers are those of
hemorrhage and perforation. Serious hemorrhage permits the
escape by the mouth of large quantities of bright, fresh blood, with a
corresponding degree of shock or collapse, and depression.
Perforation is indicated by sudden onset of intense pain, with
collapse, rapidly spreading tenderness, with abdominal rigidity and
increasing distention. In other words the symptoms of perforation are
those of acute local peritonitis of abrupt origin.
In either of these events the paramount indication is for prompt
intervention, unless the patient is already too weak to withstand the
shock of any operation. In one case this will consist of gastro-
enterostomy, with or without a gastrotomy for the purpose of
discovering the bleeding vessel and making local hemostasis. In the
other it will consist of free incision, complete toilet of the peritoneum,
with removal of all escaped material, and local attention to the site of
the perforation, doing there whatever may be needed.
Treatment.—Should the surgeon see a case of gastric
hemorrhage due to ulcer after the apparent cessation
of the active loss of blood he may easily decide to wait for a few
days until the patient has in some degree recovered strength and
atoned for such loss. On the other hand if he see the case during its
active stage he need not hesitate to open the abdomen, withdraw
the stomach, open it sufficiently for exploration, and then attack the
source of hemorrhage, be it large or small, in such manner as he
may see fit—either with the actual cautery, with a sharp spoon, with
complete excision of the ulcerated area and union of its borders by
suture, or by merely including a bleeding vessel in a loop of suture,
addressing himself at once to the formation of an anastomosis,
preferably posterior, between the stomach and the uppermost loop of
the small intestine. This procedure, which is wise in all instances,
would be imperative in nearly all save those perhaps where an
ulcerated area could be cleanly excised and its margins neatly
sutured. Should it prove that suture of the stomach wall were
impracticable its edges might be fastened to those of the abdominal
wound, a gastrostomy thus resulting, which could be later closed by
another operation.
For perforation the surgeon might have to rely, in emergency, on a
gastro-enterostomy as a relief opening, accompanied by local gauze
tamponage; the point of perforation could not be made accessible for
suture, but one should prefer suture for all cases that permit of it. In
these cases a considerable margin should be enfolded and included
within the grasp of the suture, or else the margins should be
completely excised until healthy tissue is reached. In rare instances
it has been feasible to fit into a perforation a drainage tube, or to
pack about it a gauze strip which should conduct from the stomach
cavity directly to the abdominal wound. The question of excision of
the entire ulcerated area should rest entirely upon the possibility of
repairing the defect by sutures, and this will depend in large degree
upon the location of the ulcer and the freedom with which the
stomach can be manipulated, especially with which it can be
withdrawn into the wound.
Practically every case of perforation thus operated will demand
posterior as well as anterior drainage. Aside from the treatment of
the stomach itself the general peritoneal cavity needs the same
thoroughness of cleansing and the same care in every manipulation
that would be given in a case of well-marked peritonitis already
established.
GASTRIC FISTULAS.
This term has reference especially to external fistulous openings,
which are an exceeding rarity save as relics of injury or of operation.
They have been known to occur spontaneously by perforation of an
ulcerated and adherent stomach, such perforations occurring either
in direct line or irregularly in the direction of least resistance.
Traumatic fistulas result usually from gunshot or stab wounds, or are
due to incomplete union of an opening deliberately made. In any
event they permit of the escape of more or less of the stomach
contents. Their tendency is usually toward spontaneous repair, but
this is often so slow or so incomplete that it needs to be hastened by
stimulation of the fistulous tract with silver nitrate, the actual cautery,
curetting, or by a complete resection of the entire tissue involved,
and a neat reunion with suture.
Intra-abdominal gastric fistulas result usually from perforation of
gallstones or the escape of foreign bodies. Produced in this way they
empty usually, though not always, into some neighboring portion of
the intestinal canal.
PHLEGMONOUS GASTRITIS.
Under this term is included a suppurative or necrotic inflammation
of the stomach wall, beginning probably in the submucosa, but
extending in both directions. It appears in two forms—the
circumscribed and diffuse.
Symptoms.—The symptoms of the latter are those of an intensely
acute gastritis with rapid, almost inevitably fatal
course, beginning with severe pain, quickly followed by faintness and
collapse, with early vomiting, vomited matter being first bile-stained,
then containing blood. The sensation of nausea is extreme and a
complaint of thirst constant. Frequently there are hiccough and
peculiar and uncontrollable general restlessness. Pain is, however, a
variable feature, and some cases are too rapidly necrotic to afford
much pain or tenderness. The pulse is rapid, weak, and poor, and
the temperature usually runs high. After a short time the abdomen
may be much distended, while symptoms of paralytic ileus (i. e.,
obstruction), supervene, though occasionally there is offensive
diarrhea. A well-marked case of this type comes on with fulminating
suddenness, patients later becoming apathetic and dying in stupor.
About all this there is nothing peculiarly characteristic, and similar
symptoms might be caused by mesenteric thrombus, by acute
pancreatitis, or acute gangrenous cholecystitis.
Symptoms of the more circumscribed form are similar to those just
described, but of less severity. The pain and vomiting appear
suddenly, but are less intense. If time be afforded for formation of
abscess a distinct tumor may be felt. Appetite is lost and food
regurgitated. A localized lesion favorably placed might lead to
adhesions and circumscribed collection of pus, assuming the
subphrenic or some less typical form. The pyloric end of the stomach
is more commonly involved in such a process and affords evidence
to the effect that it begins as an infection, the port of entry being
usually a gastric ulcer.
Treatment.—Treatment would be surgical if any were available,
but has never yet been applied sufficiently early to
save an acute, generalized case. On the other hand, when the lesion
has been local and has led to subsequent phlegmon, cases have
been successfully opened and drained.