Syrup
Formula 2: Non – Medicated Syrup (Aromatic syrup)
Formula 2: Non – Medicated Syrup (Aromatic syrup): Prepare 50 mL
No. Ingredient Master Formula
1 Lemon spirit 10 mL
2 Simple syrup q.s. 1000 mL
Procedure:
1. Simple mixing of the two ingredients.
- Use of preparation:
- Labeling:
- Storage:
Lemon spirit:
Rx Lemon Oil 10 % v/v
In Alcohol (90%) q.s.
Procedure:
1. Measure the specified volumes of lemon oil and alcohol.
2. Transfer the two liquids to the final container.
3. Perfectly close the final container and shake well.
Formula 3: Medicated Syrup: Prepare 50 ml
Formula 3: Indomethacin Syrup 5mg/ml: Prepare 50 mL
No. Ingredient Master Formula
1 Indomethacin 500 mg
2 Vanilla flavor 0.1 mL
3 Concentrated chloroform water. 2.5 mL
4 Syrup to 100 mL
Procedure:
1. Open capsules and empty the contents into a mortar and triturate.
2. Levigate the powder with small amount of simple syrup until smooth paste is
formed.
3. Add more simple syrup to the paste until liquid is formed and transfer the liquid
into a container.
4. Use additional simple syrup to rinse the remaining drug from the mortar and
pour into the container.
5. Make up to final volume with simple syrup.
6. Shake well and label.
Indication : Pain and inflammation in rheumatic disease
Stability : 60 days
Storage : Refrigerate and protect from light
Suspension
Formula 1: Calamine lotion BP
Principle:
It is a suspension containing in-diffusible Solids for external use. Here we use bentonite
as a suspending agent, dispersion of bentonite is observed if it is mixed intimately with
insoluble medicament i.e., calamine. The zinc oxide used here acts as astringent &
protective agent. Sodium citrate causes partial deflocculation of calamine and transfers
bentonite from gel to solid form in its absence. Hence it is thicker & difficult to pour
from bottle.
Requirements:
Apparatus Required:
Mortar & pestle, weigh balance, measuring cylinder, glass rod, spatula, beaker, funnel
etc.
Chemical Required:
Calamine, Zinc oxide, Bentonite, Glycerin, sodium citrate, Liquefied phenol, rose
water,
Purified water.
Formula 1: Calamine lotion BP: Prepare 10 ml
No. Ingredient Master formula Scaled formula
1 Calamine 150 gm
2 Zinc oxide 50 gm
3 Bentonite 30 gm
4 Glycerin 50 ml
5 Sodium citrate 5 gm
6 Liquefied phenol 5 ml
7 Purified water, freshly boiled 1000 ml
and cooled
Procedure:
1. Mix the weighed amounts of Calamine, ZnO, Bentonite in a mortar & pestle
until evenly dispersed. Bentonite must be distributed very well among the
calamine and zinc.
2. Dissolve Na citrate in 5 ml of water and add this solution to the mortar and
triturate to make a smooth paste with the powders.
3. Add required amounts of liquefied phenol & Glycerin.
4. Mix well then, add the water gradually to the mortar to make the preparation
pourable.
5. Make up to the final volume with water in the final container.
Directions:
Shake well before use. To be applied 2-3 times daily to the skin and allow to dry.
Uses:
1. This is used as astringent.
2. Used as smoothening agent and gives relief from itching and pain during skin
diseases and infections.
Storage:
Stored in a well closed container dark in a cool place at a temperature not exceeding
25oC.
Category: Skin protectant.
Note: phenol is caustic.
