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Ibnu Rozak
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Preface

The journey into stem cell research represents one of the most profound
scientific endeavors of our time. From the early exploration of basic cell
biology to the groundbreaking advances in regenerative medicine, stem
cells have opened up new possibilities for healing and restoring the human
body. "Discovering the Miracle of Stem Cells" seeks to highlight these
extraordinary potentials, particularly focusing on the contributions made
by Indonesian researchers to this rapidly evolving field.

This book covers a wide array of topics within stem cell science, encompassing both
fundamental research and clinical applications. It underscores the pivotal role that stem cells have
played in transforming modern medicine. The initial chapters, such as "Stem Cell Culture
Techniques" by Jeanne Adiwinata Pawitan, provide key insights into culturing methods and the
development of mesenchymal stem cells (MSCs), which are among the most widely applied stem
cells in regenerative therapies. Clinical applications are thoroughly explored in chapters like
"Stem Cell for Orthopaedics Application" by Ismail Hadisoebroto Dilogo, as well as
discussions on the potential use of stem cells in treating diabetes and skin aging, with contributions
from experts such as Siufui Hendrawan and Winawati Eka Putri. These chapters are enriched
with fascinating case studies in orthopedics, cardiology, dermatology, and neurology, offering
a comprehensive overview of how stem cells are being utilized in diverse medical fields.

One notable chapter, "The Potential of CD34+ Stem Cells in Increasing Fibroblast and
Collagen Levels in Ultraviolet B Exposed Skin," co-authored by Basuki Supartono, explores
the use of stem cells in anti-aging therapies, providing promising avenues for skin regeneration. In
addition, the book delves into the ethical and legal dimensions of stem cell research, expertly
analyzed by Dito Anurogo in the chapter "The Art of Socio-ethical and Legal Dimensions in
Stem Cell Research." The articles in this book have been carefully selected, reviewed, edited,
and proofread under the supervision of the National Research and Innovation Agency (BRIN),
ensuring the highest level of academic integrity.

On a broader scale, this book not only consolidates existing knowledge in the field of stem
cells but also introduces new perspectives and clinical applications specific to the Indonesian
healthcare context. While global research on stem cells is vast, this work offers a unique focus on
Indonesia's advancements, illustrating how local research and clinical trials are contributing to
global progress. By situating these developments alongside international breakthroughs,
"Discovering the Miracle of Stem Cells" adds a regional dimension to the existing body of
literature in regenerative medicine, offering insights into localized challenges and solutions often
overlooked in mainstream research.
As a researcher and clinician, I have had the privilege of witnessing firsthand the
remarkable potential of stem cell therapies to provide hope and relief to patients suffering from a
wide range of conditions.

I am deeply thankful to my colleagues, research teams, and collaborators, whose


unwavering dedication and tireless efforts have made this book possible. Their contributions have
been instrumental in advancing our collective understanding of stem cells and propelling this
pioneering field to the forefront of medical innovation. I also extend my sincere gratitude to the
National Research and Innovation Agency (BRIN) for their invaluable support.

I offer my heartfelt thanks to the readers of this book, particularly practitioners, researchers,
and students in the biomedical sciences. My hope is that this book will serve both as a valuable
reference and a source of inspiration, encouraging further research and innovation in stem cell
science.

Lastly, I wish to acknowledge the steadfast support of my wife, Dr. Prita Kusumaningsih,
SpOG, my family, my children, grandchildren, and friends, who have continuously encouraged
me throughout the writing process. Their patience and understanding have been invaluable in
bringing this work to completion.

As we continue to explore the vast potential of stem cells, I believe we are only beginning
to realize the full scope of their capabilities. "Discovering the Miracle of Stem Cells" is not
merely a record of scientific discoveries; it is a testament to the future of medicine, where healing
and regeneration become achievable for all.

Jakarta, October 12th, 2024

Editor

Prof. Dr. dr. Basuki Supartono, Sp.O.T., F.I.C.S., M.A.R.S

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