BI O MÉR I EUX
VIDAS®
ANTI-MÜLLERIAN HORMONE
On-hand testing for greater patient comfort
Did you know? VIDAS®
1/6 couples worldwide experience some form of infertility
Polycystic Ovary Syndrome (PCOS) affects 5-10% of women
(1)
Anti-Müllerian Hormone
of reproductive age (2)
On-hand quality testing for confident decisions
In 30 years, the success rate of IVF has increased
from 10% to above (3)
30% Reliability and robustness
Greater reliability through patented proprietary raw materials
Anti-Müllerian Hormone (AMH) testing ➔ Reliable results when compared with an existing automated method*
➔ Minimal impact of pre-analytical stage on test results:
for ovarian function assessment in women ≤ 8 hours at +18/+25°C ≤ 5 days at +2/+8°C ≤ 3 freezing-thawing cycles
in closed primary tube when aliquoted
AMH FEATURES ≤ 3 cycles
≤ 8 hours ≤ 5 days
Stable over the menstrual cycle Sensitive to conformational change
LH (mIU/mL) AMH (ng/mL)
in samples (5) ❄ ❄ ❄
35 FSH (mIU/mL) 6 More accurate than Antral Follicular Count
30 5 (AFC)
25
4
Inter-operator variation makes AFC subjective
VIDAS®: an easy-to-use
●
20
3
15 ● AMH provides quantitative objective results (6) VIDAS® COMMUNITY:
benchtop platform
2
10
0
1
0
A key test within the diagnostic work-up partnering over
30 000 users
-14 -12 -10 -8 -6 -4 -2 0 2 4 6 8 10 12 14
Days
Circulatory patterns of FSH, LH and AMH during the menstrual
● Just load & go
cycle of young healthy women (4)Day 0 = day of LH surge ● Limited calibration and maintenance
● Compact instrument: easily fits into your fertility center worldwide
or laboratory
24/7 availability for your patients’ comfort
A COMPLETE SOLUTION ON
YOUR VIDAS® INSTRUMENT
1 patient = 1 test for maximum flexibility
HORMONE SEROLOGY ● On-demand testing
ASSAYS PANELS ● Results during the consultation
CLINICAL APPLICATIONS AMH HEPATITIS ➔ Less patient stress
As an indicator of the ovarian follicle reserve, Detection of ovarian dysfunction ESTRADIOL HIV ➔ Immediate integration of AMH results
AMH is useful in different contexts all along (PCOS, Premature ovarian failure…): FSH TORC into the full diagnostic work-up
the reproductive lifespan: The use of AMH rather than Follicle Stimulating LH
➔ Treatment optimization
Personalization of infertility management Hormone (FSH) or Luteinizing Hormone (LH) HCG
(IVF/ART): provides direct, more accurate assessment PROLACTIN
➔ No unnecessary ovarian stimulation
Assessment of ovarian reserve for infertility of ovulation. PROGESTERONE
investigations Monitoring of ovarian damage(surgery, TESTOSTERONE
Help to select the best stimulation protocol gonadotoxic therapies) THYROID PANEL
➔ Adapt treatment First-choice marker to detect the decline of * See package insert
➔ Avoid unnecessary stimulation the ovarian reserve.
➔ Reduce risk of hyperstimulation syndrome
BI O MÉR I EUX
AVAILABLE ON
VIDAS® INSTRUMENTS:
VIDAS®, MINI VIDAS®
AND VIDAS® 3
VIDAS® AMH
Reference number 417011
Tests / kit 30
Time to result 35 min
Sample type Serum, Plasma (Li Hep)
Sample volume 200 µL
the BIOMÉRIEUX logo and VIDAS are used, pending and/or registered trademarks belonging to bioMérieux, or one of its subsidiaries or one of its companies.
Units ng/mL - pmol/L
Any other trademark is the property of its respective owner. / bioMérieux S.A. RCS Lyon 673 620 399 / Printed in France / thera/ RCS Lyon B 398 160 242
12-18/ 9316051 008/GB/B / Document and/or pictures not legally binding. Modifications by bioMérieux can be made without prior notice / BIOMÉRIEUX,
Measuring range 0.02 – 9.00 ng/mL
Calibration & Control frequency 28 days
REFERENCES
1. https://www.eshre.eu/Guidelines-and-legal/ART-fact-sheet
2. https://www.pcosfoundation.org/
3. https://www.sart.org/History_of_IVF/
4. La Marca et al Human Reproduction 2006
5. Rustamov O et al Human Reproduction 2012
6. Anderson RA et al Fertility and Sterility 2015
bioMérieux S.A. • 69280 Marcy l’Etoile • France • Tel.: + 33 (0)4 78 87 20 00 • Fax: +33 (0)4 78 87 20 90
www.biomerieux.com • www.biomerieux-diagnostics.com-
