PHA 046 - PHARMACEUTICAL MICROBIOLOGY AND PARASITOLOGY

TERM 3- Post Test

1 Mr. P daughter was brought to the hospital because A 10. Which of the following is/are ESKAPE pathogen/s?
she has a high fever, her throat tissues are inflamed Acinetobacter baumannl!
and her tongue exhibits a strawberry-like appearance. ID. Candida albicans
After diagnosis, the doctor prescribed penicillin. What Pseudomonas aeruginosa
is the diagnosis? EnterocOccus faecalis
A Diphtheria V Staphylococcus epidermidis
B Pertussis A. I, M, IV
C Scarletina B. Iand ||
D Pyoderma C Vonly
E. Scalded Skin Syndrome D. , I, 1, IV
2. What is the etiologic agent of Weil's disease? 11, DOC for most cestodal and trematodal infections
A. Yersinia pestis A. Mebendazole
8. Bartonella quintang B lvermectin
C. Qrientia tsutsugamushi Diethylcarbamazine citrate
C
D Leptospira interroqgns Praziquantel
Ehrlichia chaffeensis 12. Three-dimensional images of live cells can be
- 3. Strain of Escherichia coli which causes Montezuma's produced with
Revenge. A Darkfield microscopy.
A EPEC (Entero-pathogenic E. coli) B. Fluorescence microscopy.
8 ETEC (Entero-toxigenic E. coli) C Transmission electron microscopy.
C. EHEC (Entero-hemorrhagic E. coli) D. Confocal microscopy.
D EIEC (Entero-inyasive E. coli) Phase-contrast microscopy
E.
E.EAEC (Entero-aggregative E. coli) 13. Which of the following is not a function of glycocalyx?
4. Brucellosis in humans is associated with the A It forms false feet for movement of an
consumption of unpasteurized milk and soft cheeses organism
made from the milk of infected goats, infected with B. Protection of bacterial cell from drying out.
Brucella C It allows the bacterium to attach to the host.
A Suis - u i D It hides the bacterial cellfrom other cells.
abortus 14. Ringworm on thescalp is known as
C. canis A Tineg capitis
D mylensis Tinea pedis
E. militensis Tineo ungulum
Gram () bacterial cell walls contain the ff. Onychomycosis
components, EXCEPT n 15. These are sexually transmitted diseases EXCEPT
A Lipoproteins A. Trypanosomiasis
B. Lipoteichoic acid B. Hepatitis B
C. Lipopolysaccharide C. Lymphagranuloma venereum
D. Outer membrane D Chícken pox
6. Characteristic of aprokaryotic bacteria fol selno g-16. Which of the following statements about fermentation
A Nuclear membrane is incorrect?
B 80s ribosome A. Fermentation releases energy from sugars or
C Peptidoglycan other organic molecules by oxidation.
D. Segmented genome B. 02 is required in fermentation.
7. German measles virus is a member of which viral C In lactic acid fermentation, pyruvic acid is
famlly? reduced by NADH to lactic acid.
A Herpes D In alcohol fermentation, acetaldehyde is
Orthomyxovirus reduced by NADH to produce ethanol
C Toga virus 2 17. The causative agent of food poisoning, TSS and skin
D Paramyxovirus boils
8 Roc-shaped bacteria curved to form commas are StaphylocOccUs epidermldis
known as B StaphylococCUS qureus
A Bacilli C StreptocoCCUS mnutans
B. Cocci StreptococCus pyoqenes
Spiral E. StreptocoCcUs pneumonia
D. Vibrios & -18. Bacteria that derive their energy from oxidation of
B 9. The following viruses possess an outer envelope of organic molecules
lipoprotein EXCEPT: A. Autotrophs
A Varlcella-zoster virus B. Heterotrophs
Papilloma virus C Chemoautotrophs
C Influenza virus
D HIV virus
D Photoautotrophs
G 19, Afemale palent presented complaints of severe pain
the pelvic area, frothy yellow vaginal D. Differentlalmedia
discharge with
an unpleasant odor, and vulvovaginal itching. 0 33. Resistant bacteria, EXCEPT:
the most probably causative agent?
What is A VRSA
A
Chlamydio trachomatis C
MRSA
Trichomonas vaginalis VRE
C. Neisserig qonorrhege D. Pseudomonas aeruginosa
D Candida alblcans A 34. State of being diseased or unhealthy within a
20. Characterized physlologlcally by a "sardonlc smile" population
A A. Morbidity
Corynebacterium diphtheria
Clostridium difficile B Prevalence
C. Incidence
Clostridium tetani D
Mortality
D
E
Clostridium botulinum 0 35. Asecondary ínfection that results from destruction of
Clostridium perfringens
21. Virus that infect bacteria normal microflora and often follows the use of broad
A Viroid spectrum antibiotics.
B Prions
A Mixed infection
C
B Subclinical infection
Bacteriophage C. Inapparent infection
D. Methanogens D Superinfection
22. Discovered the 1st
A.
chemotherapeutic agent, Salvarsan
John Snow
E Co-morbid infection
36. All of the following are macrolide antibiotics, EXCEPT:
B. Paul Erhlich
C Alexander Fleming
A Erythromycin
B Oleandromycin
D. Richard Petri C
E. Edward Jenner Vancomycin
D. Spiramycin
) 37. An antibiotic most commonly used in topica
For number 23-25
preparations.
A Hepa A A Clotrimazole
B Hepa B B. Vidarabine
C Hepa C C Griseofulvin
D. Hepa D D Bacitracin
E
Hepa E Foscarnet
A 23. Picornaviridae ) 38. What is the prominent adverse effect of
C 24. Flaviviridae aminoglycosides?
E-25. Caliciviridae A. Hepatotoxicity
8. Cardiotoxicity
Choices for numbers 26-30 C. Neurotoxicity
Diagnostic test for bacteria lnfections: D. Nephrotoxicity
A Mc Fayden's Reaction E Dermal tOxicíty
B Dlck test O39. Which of the following anti-infective is not
C Widal test bactericidal?
D. Urea breath test A Carbenicillin
E. Montoux test B. Gentamlcin
3 26. Used to determine susceptibility to scarlet fever C Cefuroxime
27. Apresumptive serological test for enteric fever D. Erythromycin
A 28. A diagnosis of anthrax E. Vancomycin
29. Aprocedure to diagnose H.pylori infection )-40. Which among the following antiviral drugs is a
E30. Adiagnosis of TB proteaseinhibitor?
o31. Mechanism of action of this anti-tubercular agent is to A Efavirenz
B Lamivudine
inhibit protein synthesis
A PZA C Zidovudine
B Streptomycin D Saquinavir
C INH
E. Abacavir
D. Ethambutol 3 41. The main host defense against bacterial exotoxin
A Activated macrophages secreting proteases
32. Thioglycollate agar is an example of
B IgG and IgM antibodies
A Enriched media
B Selective media C. Helper-T cells
Anaerobic media
 D. Modulation of host cell
response to the toOxin receptors In
C Resistance to penlcillin is known to be due to
42. Administration of toxoids confers cleavage of B-lactamase
A
Naturally acquired active immunlty Reslstance to tetracycline is due to an
Naturally acquired passive immunity enzyme that hydrolyzes the ester linkages
Artificially acquired active immunity A 50. This light-sensitive anti-fungal is reserved for
the most
D. Artificially
acquired passive immunity lifethreatening infections and is given intravenously
43. The following are A Amphotericin B
non-communicable
related to the lifestyle the person.
of
diseases and B Flucytosirne
Cancer C Polyixin B
D. Caspofungin
Diabetes mellitus Type |l B S1. The
COPD internationally recommended strategy for the
control of tuberculosis is DOTS, which stands for:
IV. HIV/AIDS A Directly Observed Short-Term Strategy
A I,IV
B Directly Observed Treatment Short Course
B I, (V
C
C Directly Observed Therapy Short Course
1, I1, II D Directly Observable Standard Treatment
D. , I, IV E Duratlon of Observed Treatment Short
044. The absorption of this antifungal is increased with fatty Course
food intake A f2. Which of the ff. statements about Pneumocystis
A Itraconazole carinil is true?
Terbinafin A. Antibodies are found only in infected
C Fluconazole immunocompromlsed hosts
D Griseofulvin B It is a ricketssia
45. This antifungal para;yzes the causative agent by C It can caUse pulmonary tuberculosis
inhibiting GABA transmission and let the body D Pathogernic for patilents with AIDS with CD4
counts of > 800 cells/ml
eliminate the paralyzed remains
E. Dlagnosls Is through sputum smear
A. Diethylcarbamazine
Albendazole microscopY
C Ivermectin Ct3. Antibodythat Is produced first in response to a
D Praziquantel
primary infection
A IgG
46. Human immunodeflciency virus targets which cell in
IgA
the immune system? (C) IgM
A CD4+ T helper cell
D. lgD
B Bcell
E. IgE
C CDB+B helper cell A 4. Antibody present in breastmik
D. CD4+ T cytotoxic cell'
Natural killer cell
(A) igG
E.
inhabits thá skin) B. IgA
B47. Anosocomial pathogen that normaly
prosthetic devices such
C jgM
and commonly contaminates D IgD
as, catheters and heart valves, leading to symptomatic E. IgE
microbemla
A S5. change in the DNA which results in an insertion or
A
A. Staphylococcusqureus deletion of one or more bases
StaphvlocoGCUS epldermis A. Frameshift mutation
CStreptocOCCus qureus B Point mutation
D. StreptocOcCUS DYOgenes C Nonsense mutation
E StreptocOCCUS mutons D Spontaneous mutation
48. Abiological vector E. InduUced mutation
DNA can be
A. Anopheles mosquito Atechnique where a small samples of
B Cockroach quickly amplified for analysis
C. Housefly A. Hybridoma
Aedes aegypti Recombinant DNA
D
E Termite C Polymerase Chain Reaction
about resistance to
49. The following statements D Cloning
antimicrobial drugsare true except: E. Fluorescence
Resistance to chloramphenicol is
due to reside in the liver
A 7. Fixed macrophages that protect and
enzyme that acetylates the drug reduced
A. Osteoclast
B Resistance to penicillin is due to B. Alveolar macrophages
affinity of transpeptidases
 complement
C. Kupfer cells A Speciflc antibody &
hemolysin
B Red blood cells &
D. Hi_tocytes Heat-inactivated patient'sserum
E Sinusoids C.
D Gulnea plg serum
Á S8. Duration of immunity of rabies vaccine is Rat red blood cells
A 2 years where antibodies cause antigensto clump
B. S years E 6. Acondition
together.
C 10 years A. Opsonisation
D 6 years B. Phagocytosis
E 20 years C. Complement fixation
A S9. Acomplement fixation diagnostic rest for syphilis is D, Neutrallzation
A. Wassermann test E. Agglutinationplasmodla that Is transmi
form of
B. Widal test
t o: Inmalarla, the
C Schick test from mosquito to human is the
D Direct ELISA A. Gametocyte
E Indirect ELISA B Merozoite

4a0 Collective term for

microbes on and inside human C Oocyst
bodies
D. Trophozoite
A. Microbial count E. Sporozoite diseases except
lead to the following
A 8. Exotoxins can
B.
Too numerous to count
Normal microbiota A Rabies
C
D Microbiofilm 8 Tetanus
E Biological flora C. Diphtherla
D Botulism
A lo Cause of Lyme disease Cholera caused
A. Borrelia burgdorferl ecreasein blood pressure
Candida albicans 9. Alife-threatening
referred to as
C Salmonella typhi by bacteria is
Limulus Polyphemus A Shock
D. Technical knock-out
E.
Treponema palidum
bacteria in a sample (c) Septic shock
method used toidentify
A
b). without Hypotension
culturing the bacteria D

Flow cytometry E Anemia manifest as tiny red

)20.Lesighs of theoral cavity which
A
B. Phage typing specks in patients infected
C
Immunofluorescence patches with central white
with Rubeola virus
D Fluorescent in situ Hybridization Erythema infectiosum
ELISA A.
occur in this Macular rash
(03. Hemolytic disease of the newborn will
A C Fever blisters
condition: sensitlzed
A. Second or higher pregnancy of Rh(+) D Koplik's spots
with an Negri bodies
Rh(-) Mother, Rh (+) baby E.
causative agent of genital herpes
father 1. The most common
Rh(+)
Second or higher pregnancy of father A. HSV-1
Rh(-)
mother, Rh(+) baby with an B HSV-2
sensltized
Second or higher pregnancy of C HSV-3
with an Rh(-)
Rh(+) Mother, Rh (+) baby D HSV-4
father E. HSV-6
Rh(-)
Second or higher pregnancy of father low-molecular weight compound which i
D F 2. This is a against
mother, Rh(+) baby with an Rh(+) very effective agalnst influenza A virus but not
influenza A
of
E. Second or higher
pregnancy of Rh(-) influenza B virus. The incidence
wih an Rh(-) father of this drug.
mother, Rhl+) baby infections is greatly reduced by the use
the increase in Sibromycin
a 04. The following are involved in fever except:
A.
abnormally high body temperature or B. Anthramycin
A. Endotoxins C Sulfaguanidine
B Exotoxins D. Acycloguanosine
C. Lipopolysaccharides E. Amantadine
pneumonia and still
D Interleukin-1 (q3. This is the Commonest cause of global in isolates
E TNF-a responds well to penicillin despitea
indicator system of a showing reduced susceptibility to this agent.
What is included in the
B (5. complement fixation test?
 A
B
Leglonella pneumaphila Bacllus cereus
MycoplYsma pneumonia D
This is the most common form
of botulism

D.
Streptococcus pneumoniae
Haemophilus influenza A Infant botulism
Foodborne botulism
B
E. Streptococcus pyogenes Wound botulism
C
r4. Characteristics of the causative agent of tetanus, D. Endemic botulism
chills, fever and
except:
A 3. Apoultry farmer has symptomsof large number of
A
Gram positive headache. Two weeks ago he lost a
B disease. What is the
undiagnosed
Produces endospores his livestock to an
C Obligate arobe most likely condition of the farmer.
D Transmitted through contaminated soil A Psittacosis
E.
Produces a potent neurotoxin 0-fever
5. Which of thefollowing is not a tickborne disease? C Anthrax
A. D. Ornithosls
Babesiosls by insects. Which of
Ehrlichiosls An ill patient denied being bitten
following Rickettsial infection is most likely the
Lyme disease the
cause of the Illness?
D. Relapsing fever
E. Tularemia
A. Ricketsial pox
B. 0-fever
r6. Causative agent for Undulant fever. Scrub typhus
A. Bartonella henselae D. Rocky mountain spotted fever
B Borrela burqdorterl 5. A malarial organism producingcellsringlike
and
C Brucella melitensis crescentlike forms within red blood
Bacillus anthracis Plasmodium vivax
Bordetella pertussis
E.
B) Plasmodium falciparum
A7. This refers to inflammation of theurinary bladder. C Plasmodium malariae
A. Cystitis D. Plasmodium ovale
Urethritis changes in the
Ureteritis 6. This ís a condition where there are small later
antigenic structure of an organism which mat
C
D Pyelonephritis result to an epidemic
E. Nephritis A Antigenic shift
method of
A 78. Which of the following is an indirect B Antigenic drift
estimating bacterial number? Tolerance
C
A Turbidity method
D Immunity
Serial dilution influenza
7. this conditlon that results when children with
B
C Most probable number f
or varicella are given Aspirin
D Filtration A Herxheimer reaction
E Direct microscopic count
B. Salicylism
Á 29. Which of the following drugs is most resistant to the C. Reye syndrome
action of penicilinase?
D Asthma
A. Methicillin
B. Amoxicillin This is/are examples of viruses classified under
C Benzathine penicillin Paramyxoviridae family
Influenza virus
D. Ticarcillin
E. Mezlocillin
Respiratory syncitial Virus
Measles virus
20. Apatient presents with an abscess. The pus was
examined containing yellow granules. The sample was A. Ionly
tested negative to acid-fast bacili. The patient most B l only
likely has C. land ll only
A Nocardiosis D Iland lIlionly
B. Actinomycosis E 1, land I
C Streptococcal infection (9. Koplik's spots seen among patients with measles are
R. Staphylococcal infection usually locallzed in the
Agoatfarmer presents with a fever of unknown A Upper Extremities
A Lower Extremities
origin, which of the following organism is responsible B
C. Mouth
for thiÇ?
AJ B. melitensis D. Scalp
B B. abortus V0. This/these statement/s is/are regarding patients with
C. B. Suis measles during pregnancy
 may result to birth defects C
is associated with spontaneous abortions D R
may also result to premature labor E. M
Human Papilloma Vaccine
A. Ionly 4 )95.
B. |only A. P
C, Iand ll only B. H
Iland Illonly C.
D. R
E. I,Il and I
E. M
Vaccine
( 96. Equine West Nile Virus
For number 91-100
A. C
P - mRNA Vaccine
B. Y
H-Protein subunit Vaccine C. X
A-Viral Vector Vaccine
R- Virus-like Particle (VLP) Vaccine E.
M- Conjugated Vaccine Hepa B Vaccine
97
X- Nucleic Acid Vaccine A
C- Subunit Vaccine B C
Y- Attenuated Vaccine C M
91. Pfizer Vaccine D.
A. P E. R
H 98 H. Influenza Type B Vaccine
A A. H
C.
R B. A
D.
M C. R
E
J&J Janssen Vaccine D
92.
E Y
A. MMR Vaccine
H 99
B.
C A
D A R
B
D. R
C.
E
Moderna Vaccine D.
93
A E
CMV Vaccine
H D100.
A. H
A
D R B. A
M C. C
E
Novovax Vaccine D. P
94.
A P
H