Name : MR RAMA SWAMY NAIDU B Age : 75 Yr(s) Sex :Male

Registration No : MH010763869 Lab No : 212406004412BIO

Patient Episode : C17000019331 Collection Date : 08 Jun 2024 09:40
Referred By : DR. SATISH KUMAR A Reporting Date : 08 Jun 2024 13:29
Receiving Date : 08 Jun 2024 09:40
BIOCHEMISTRY
TEST RESULT UNIT BIOLOGICAL REFERENCE INTERVAL

SERUM CREATININE 1.42 # mg/dl [0.80-1.30]

METHOD:JAFFE KINETIC
*eGFR 48.0 # ml/min/1.73sq.m [>60.0]

Disclaimer :
eGFR which is primarily based on Serum Creatinine is a derivation of CKD-EPI 2009
equation normalized to1.73 sq.m BSA and is not applicable to individuals below 18 years.
eGFR tends to be less accurate when Serum Creatinine estimation is indeterminate e.g.
patients at extremes of muscle mass, on unusual diets etc. and samples with severe
Hemolysis / Icterus / Lipemia.

Specimen: Serum

SERUM SODIUM (Indirect ISE) 133.0 # mmol/l [136.0-146.0]

Specimen: Serum
SERUM POTASSIUM (Indirect ISE) 4.42 mmol/l [3.50-5.10]
Name : MR RAMA SWAMY NAIDU B Age : 75 Yr(s) Sex :Male
Registration No : MH010763869 Lab No : 212406004412BIO
Patient Episode : C17000019331 Collection Date : 08 Jun 2024 09:40
Referred By : DR. SATISH KUMAR A Reporting Date : 08 Jun 2024 13:29
Receiving Date : 08 Jun 2024 09:40
BIOCHEMISTRY
TEST RESULT UNIT BIOLOGICAL REFERENCE INTERVAL

BILIRUBIN TOTAL / DIRECT Specimen: Serum

Serum BILIRUBIN-TOTAL (DPD) 0.62 mg/dl [0.30-1.20]

Serum BILIRUBIN-DIRECT(Diazotisation) 0.08 mg/dl [<0.2]
BILIRUBIN - INDIRECT (Calculated) 0.54 mg/dl [0.20-1.00]

At the end of 12 hrs: 7.5 mg/dL

At the end of 24 hrs: 11.5 mg/dl
At the end of 48 hrs: 13 mg/dl
At the end of 72 hrs: 15 mg/dl
At the end of 4 days: 17 mg/dl
After 5 days: 15mg/dl
Note: The above reference ranges apply to well born babies between 35 to 38 weeks

Specimen : Serum
Serum SGPT/ ALT 11 U/L [<50]
Method: Enzymatic UV without P5P
Name : MR RAMA SWAMY NAIDU B Age : 75 Yr(s) Sex :Male
Registration No : MH010763869 Lab No : 212406004412BIO
Patient Episode : C17000019331 Collection Date : 08 Jun 2024 09:40
Referred By : DR. SATISH KUMAR A Reporting Date : 08 Jun 2024 13:29
Receiving Date : 08 Jun 2024 09:40
BIOCHEMISTRY
TEST RESULT UNIT BIOLOGICAL REFERENCE INTERVAL

GLUCOSE- Random
Specimen - Plasma
Plasma GLUCOSE- Random 79 mg/dl [<140]
Method: Hexokinase

Calcium Total Specimen- Serum

SERUM CALCIUM (Arsenazo III) 9.20 mg/dl [8.80-10.60]

----------------------------END OF REPORT---------------------------

Dr. Sweta Shivashanker

KMC-81102. Consultant Biochemistry
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 20:35 Hrs
Sample Processed At CORE Gurugram

PANEL NAME
MULTIPLE MYELOMA COMPREHENSIVE PANEL QUANTITATIVE, SERUM

SPECIMEN INFORMATION
Serum Collected on 08/06/2024 , 00:00 Hrs

CLINICAL HISTORY
-

CLINICAL RESULT

PROTEIN ELECTROPHORESIS

Test Name Result Unit(s) Biological reference Interval

Total Protein 6.25 g/dL 6.4-8.2
(Biuret)

Albumin 4.01 g/dL 3.57-5.42

(Gel Electrophoresis)

Alpha 1 Globulin 0.29 g/dL 0.19-0.40

(Gel Electrophoresis)

Alpha 2 Globulin 0.96 g/dL 0.45-0.96

(Gel Electrophoresis)

Beta Globulin 0.77 g/dL 0.30-0.59

(Gel Electrophoresis)

Gamma Globulin 0.22 g/dL 0.71-1.54

(Gel Electrophoresis)

Albumin/Globulin Ratio 1.79 Ratio 1.0-2.2

“M” Band See Interpretation - Absent

INTERPRETATION

A faint band seen in Gamma region.

File

Page 1 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 20:35 Hrs
Sample Processed At CORE Gurugram

COMMENTS

1. Serum protein electrophoresis is commonly used to identify multiple myeloma & related disorders.
2. Electrophoresis is a method of separating proteins based on their physical properties & the pattern is dependent on the fractions of 2 types of
protein: Albumin & Globulin (alpha1, alpha2, beta & gamma).
Components Compositions Interferences
Albumin Albumin Lipoproteins, Drugs, Bilirubin, Radiological contrast
Alpha1 - globulins α -1Albumin, α - 1 acid glycoprotein -
Alpha2 - globulins α - 2 macroglobulin, haptoglobin Haptoglobin - haemoglobin complex
Transferrin, β-lipoprotein, IgA, IgM & sometimes IgG with
Beta globulins Fibrinogen
complement protein
Gamma globulins IgG, IgA, IgM, IgD, IgE CRP
• The following conditions require serum immunofixation to differentiate monoclonal and polyclonal disorders.
• (A) A well defined 'M' band (B) Faint band. (C) Chronic inflammatory pattern (decreased Albumin, increased Alpha, increased Gamma region),
which may mask the monoclonal band. (D) Isolated increase in any region, with an otherwise normal pattern.
• Shouldering of albumin peak along anodal or cathodal side may be seen with lipoproteins, drugs, bilirubin or radiological dyes.

Page 2 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 20:35 Hrs
Sample Processed At CORE Gurugram

PANEL NAME
MULTIPLE MYELOMA COMPREHENSIVE PANEL QUANTITATIVE, SERUM

SPECIMEN INFORMATION
Serum Collected on 08/06/2024 , 00:00 Hrs

CLINICAL HISTORY
-

CLINICAL RESULT

BETA-2-M

Test Name Result Unit(s) Biological reference Interval

Beta 2 Microglobulin 6569.08 ng/mL 800 - 2340
(Turbidimetric)

COMMENTS

1. Serum Beta2 Microglobulin (ß2M) has been identified as the light chain of the HLAA, B, and C major histocompatibility complex antigens, 100 amino
acids in length and non covalently associated with the heavy chain.

2. B2M occurs on the surface of nucleated cells abundantly on lymphocytes and monocytes and on many tumor cell lines.

3. Elevated serum concentrations in the presence of a normal glomerular filtration rate suggest increased ß2M production or release. Increased levels
may be seen in lymphoproliferative diseases such as multiple myeloma, ßcell chronic lymphocytic leukaemia, Hodgkin's diseases, non-Hodgkin's
lymphoma, systemic lupus erythematosus, rheumatoid arthritis, Sjogren's syndrome, Crohn's disease, and certain viral infections, including
cytomegalovirus, nonA and nonB hepatitis and infectious mononucleosis. Elevated serum levels have also been observed in some hemodialysis patients
and in renal transplant rejection.

4. Measurement of ß2M is reportedly the most reliable test for distinguishing upper from lower urinary tract infections, and a useful method for assessing
the results of therapy and diagnosing recurrences of acute pyelonephritis using serial determinations.

Page 3 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 20:35 Hrs
Sample Processed At CORE Gurugram

PANEL NAME
MULTIPLE MYELOMA COMPREHENSIVE PANEL QUANTITATIVE, SERUM

SPECIMEN INFORMATION
Serum Collected on 08/06/2024 , 00:00 Hrs

CLINICAL HISTORY
-

CLINICAL RESULT

IMMUNOFIXATION ELECTROPHORESIS (IFE)- SERUM

Test Name Result(s)

IgG Band
See Interpretation
(Gel Electrophoresis)

lgM Band
Absent
(Gel Electrophoresis)

lgA Band
Absent
(Gel Electrophoresis)

Kappa Band
See Interpretation
(Gel Electrophoresis)

Lambda Band
Absent
(Gel Electrophoresis)

M-Spike See Interpretation

Impression See Interpretation

Interpretation Faint band seen in Gamma region corresponding to IgG and

Kappa. Kindly correlate with clinical and radiological findings
and follow-up.

Page 4 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 20:35 Hrs
Sample Processed At CORE Gurugram

COMMENTS

Serum protein electrophoresis Serum Immunofixation Results

One heavy chain (IgG/ IgM/IgA) with

M band detected or distinct band Suggestive of Monoclonal Gammopathy
one light chain Kappa/Lambda

Suspicious/poorly defined band. The level or spike( is too low to quantify or

One heavy chain (IgG/ IgM/IgA) with to call it a definite M band. Such suspected cases of unknown significance
Thin distinct band/ very thin band
one light chain Kappa/Lambda MGUS, Smouldering myeloma) requires follow ups in 3-6months. This
pattern may also be a case of myeloma on therapy.

Page 5 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 20:35 Hrs
Sample Processed At CORE Gurugram

1. Light chain disease, suggest urine Immunofixation

Either Kappa/Lambda chain only, no
M band/distinct/Thin distinct band 2. IgD or IgE disease
heavy chain band
3. Multiple bands in lambda indicate polymerised form

Only heavy chain with no apparent

Distinct/thin distinct band Heavy chain disease should be ruled out. Suggested Immunoselection.
light chain

Only heavy chain with no apparent

Very thin distinct band Cryoglobulin
light chain

2 band with same or

1. Biclonal Gammopathy
2 M band/ 2 distinct band different heavy chain and 2 band
2. Paraprotein (monomer / polymer of Immunoglobins)
with same or different light chain.

Usually indicates a polyclonal gammopathy e.g. TB, gamma globulin with

One or more heavy chain with both
A diffuse band in gamma globulin both light chains Hepatitis, SLE, AIDS, and some autoimmune region (K
light chain (kappa/Lambda)
and L) bands disorders.

The free light chain is to assess renal function. A urine immunofixation

One heavy chain with one light chain electrophoresis is recommended to know if there are free light in the urine
Thin / Very thin distinct band
and different free light chain. or even worse if there are heavy chains. Light chains are an indication that
the tubules are malfunctioning.

Page 6 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 23:01 Hrs
Sample Processed At CORE Gurugram

PANEL NAME
MULTIPLE MYELOMA COMPREHENSIVE PANEL QUANTITATIVE, SERUM

SPECIMEN INFORMATION
Serum Collected on 08/06/2024 , 00:00 Hrs

CLINICAL HISTORY
-

CLINICAL RESULT

KAPPA/LAMBDA- FREE LIGHT CHAIN

Test Name Result Unit(s) Biological reference Interval

Free Kappa (light chain) 1312.14 mg/L 3.3-19.4
(Turbidimetric)

Free Lambda (light chain) 3.16 mg/L 5.71-26.30

(Turbidimetric)

Free Kappa : Lambda Ratio 415.23 Ratio 0.26-1.65

COMMENTS

1. Serum light chain test is used in the diagnosis and monitoring of patients with monoclonal light chain diseases.
2. Immuonglobulin moleclues consist of two identical heavy chains (alpha, delta, epsilon, gamma, or mu) and two identical light chains (kappa or lambda).
3. In healthy individuals, the majority of light chains in serum are covalently linked to the heavy chains and the level of free light chains is low.
4. Elevated level of monoclonal free light chain are associated with malignant plasma cell proliferation (multiple myeloma), primary amyloidosis, and light
chain deposition disease.
5. Raised serum levels of polyclonal free light chain may be associated with autoimmune diseases such as systemic lupus erythematous.

Page 7 of 8
 Case ID 102240093508
Patient Name RAMA SWAMY NAIDU MH010763869
Age/Sex 75 years / Male
Hospital Location Yeswanthpur
Hospital Name Manipal Hospital, Yeswanthpur
Physician Name SATISH KUMAR A
Date & Time of Accessioning 09/06/2024 , 16:51 Hrs
Date & Time of Reporting 11/06/2024 , 22:25 Hrs
Sample Processed At CORE Gurugram

PANEL NAME
MULTIPLE MYELOMA COMPREHENSIVE PANEL QUANTITATIVE, SERUM

SPECIMEN INFORMATION
Serum Collected on 08/06/2024 , 00:00 Hrs

CLINICAL HISTORY
-

CLINICAL RESULT

IMMUNOGLOBULIN PROFILE

Test Name Result Unit(s) Biological reference Interval

IgG level, serum (Method: Turbidimetric) 2.98 g/L 6.103 - 16.16
(Turbidimetric )

IgA level, serum (Method: Turbidimetric) <0.020 g/L 0.84 - 4.99

(Turbidimetric)

IgM level, serum (Method: Turbidimetric) <0.101 g/L 0.35-2.42

(Turbidimetric )

COMMENTS

1. Serum immunoglobulin levels are useful for detecting or monitoring of monoclonal gammopathies and immune deficiencies.

2. The gamma globulin band, as seen in conventional serum protein electrophoresis, consists of 5 immunoglobulins. In normal serum, about 80% is
immunoglobulin G (IgG), 15% is immunoglobulin A (IgA), 5% is immunoglobulin M (IgM), 0.2% is immunoglobulin D (IgD), and a trace is immunoglobulin
E (IgE).

3. Elevations of IgG, IgA, and IgM may be due to polyclonal immunoglobulin production.

4. Monoclonal gammopathies of all types may lead to a spike in the gamma globulin zone seen on serum protein electrophoresis. Monoclonal elevations
of IgG, IgA, IgD, and IgE characterize multiple myeloma. Monoclonal elevations of IgM occur in macroglobulinemia.

5. Decreased immunoglobulin levels are found in patients with congenital deficiencies

Page 8 of 8
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CŌRE DIAGNOSTICS TM
Name : MR RAMA SWAMY NAIDU B Age : 75 Yr(s) Sex :Male
Registration No : MH010763869 Lab No : 212407013136BIO
Patient Episode : C17000020799 Collection Date : 20 Jul 2024 14:12
Referred By : DR. SATISH KUMAR A Reporting Date : 20 Jul 2024 14:59
Receiving Date : 20 Jul 2024 14:12
BIOCHEMISTRY
TEST RESULT UNIT BIOLOGICAL REFERENCE INTERVAL

SERUM CREATININE 1.43 # mg/dl [0.80-1.30]

METHOD:JAFFE KINETIC
*eGFR 47.6 # ml/min/1.73sq.m [>60.0]

Disclaimer :
eGFR which is primarily based on Serum Creatinine is a derivation of CKD-EPI 2009
equation normalized to1.73 sq.m BSA and is not applicable to individuals below 18 years.
eGFR tends to be less accurate when Serum Creatinine estimation is indeterminate e.g.
patients at extremes of muscle mass, on unusual diets etc. and samples with severe
Hemolysis / Icterus / Lipemia.

----------------------------END OF REPORT---------------------------

Dr. Sweta Shivashanker

KMC-81102. Consultant Biochemistry
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:26
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
Multiple Myeloma Comprehensive Panel Quantitative, Serum
Parameters Result Unit Biological Reference Interval
Kappa/Lambda- Free light chain
Kappa- Free Light Chain, Serum H 1017.020 mg/L 3.3-19.4
Turbidimetric/Immunoturbidimetric
Lambda - Free Light Chain, Serum L 2.550 mg/L 5.71-26.30
Turbidimetric/Immunoturbidimetric
Free Kappa : Lambda Ratio H 398.831 Ratio 0.26-1.65
Calculated

Comments
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

1. Serum light chain test is used in the diagnosis and monitoring of patients with monoclonal light chain diseases.
2. Immuonglobulin moleclues consist of two identical heavy chains (alpha, delta, epsilon, gamma, or mu) and two identical
light chains (kappa or lambda).
3. In healthy individuals, the majority of light chains in serum are covalently linked to the heavy chains and the level of free
light chains is low.
4. Elevated level of monoclonal free light chain are associated with malignant plasma cell proliferation (multiple myeloma),
primary amyloidosis, and light chain deposition disease.
5. Raised serum levels of polyclonal free light chain may be associated with autoimmune diseases such as systemic lupus
erythematous.

Dr. Shivani Sharma Dr. Deepthy Sahadevan

DCP, DNB, DipRCPath. Ph. D.
Reg. No. 1906
Page 1 of 7
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:26
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
Multiple Myeloma Comprehensive Panel Quantitative, Serum
Parameters Result Unit Biological Reference Interval

Beta 2 Microglobulin

Beta 2 Microglobulin 6428.57 ng/mL 800-2340

Nephelometry

Comments

1. Serum Beta2 Microglobulin (ß2M) has been identified as the light chain of the HLA-A, B, and C major histocompatibility
complex antigens, 100 amino acids in length and non covalently associated with the heavy chain.
2. ß2M occurs on the surface of nucleated cells abundantly on lymphocytes and monocytes and on many tumour cell lines. Its
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

function is unknown, but it may control the expression and on the cell surface.
3. Elevated serum concentrations in the presence of a normal glomerular filtration rate suggest increased ß2M production or
release. Increased levels may be seen in lymphoproliferative diseases such as multiple myeloma, ßcell chronic lymphocytic
leukaemia, Hodgkin's diseases, non-Hodgkin's lymphoma, systemic lupus erythematosus, rheumatoid arthritis, Sjogren's
syndrome, Crohn's disease, and certain viral infections, including cytomegalovirus, nonA and nonB hepatitis and infectious
mononucleosis.
4. Elevated serum levels have also been observed in some hemodialysis patients and in renal transplant rejection.
5. Measurement of ß2M is reportedly the most reliable test for distinguishing upper from lower urinary tract infections, and a
useful method for assessing the results of therapy and diagnosing recurrences of acute pyelonephritis using serial
determinations.

Dr. Shivani Sharma Dr. Deepthy Sahadevan

DCP, DNB, DipRCPath. Ph. D.
Reg. No. 1906
Page 2 of 7
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:26
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
Multiple Myeloma Comprehensive Panel Quantitative, Serum
Parameters Result Unit Biological Reference Interval
Immunoglobulin Profile
Immunoglobulin IgA L <0.020 g/L 0.84 - 4.99
Turbidimetric
IgG level, serum L 2.530 g/L 6.103 - 16.160
Turbidimetric
Immunoglobulin, IgM L <0.101 g/L 0.35-2.42
Turbidimetric

COMMENTS
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

1. Serum immunoglobulin levels are useful for detecting or monitoring of monoclonal gammopathies and immune
deficiencies.
2. The gamma globulin band, as seen in conventional serum protein electrophoresis, consists of 5 immunoglobulins. In normal
serum, about 80% is immunoglobulin G (IgG), 15% is immunoglobulin A (IgA), 5% is immunoglobulin M (IgM), 0.2% is
immunoglobulin D (IgD), and a trace is immunoglobulin E (IgE).
3. Elevations of IgG, IgA, and IgM may be due to polyclonal immunoglobulin production.
4. Monoclonal gammopathies of all types may lead to a spike in the gamma globulin zone seen on serum protein
electrophoresis. Monoclonal elevations of IgG, IgA, IgD, and IgE characterize multiple myeloma. Monoclonal elevations of
IgM occur in macroglobulinemia.
5. Decreased immunoglobulin levels are found in patients with congenital deficiencies

Dr. Deepthy Sahadevan

Ph. D.

Page 3 of 7
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:26
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
TEST NAME
IMMUNOFIXATION ELECTROPHORESIS (IFE)- SERUM
SPECIMEN INFORMATION
Serum Collected On 22-Jul-2024 10:00

RESULT

Test Name Result(s)

IgG Band Absent
IgM Band Absent
IgA Band Absent
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

Kappa Band See Interpretation

Lambda Band Absent
“M” Band See Interpretation
Impression See Interpretation
INTERPRETATION A faint band seen in gamma region corresponding to Kappa.
Before diagnosing this as Kappa light chain disease; presence
of IgD/IgE type of myeloma protein should be ruled out.
Advice urine Immunofixation.

COMMENTS

Dr. Shivani Sharma Dr. Deepthy Sahadevan

DCP, DNB, DipRCPath. Ph. D.
Reg. No. 1906
Page 4 of 7
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:26
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
Serum protein electrophoresis Serum Immunofixation Results
M band detected or distinct One heavy chain (IgG/ Suggestive of Monoclonal Gammopathy
band IgM/IgA) with one light
chain Kappa/Lambda
Thin distinct band/ very thin One heavy chain (IgG/ Suspicious/poorly defined band. The level or spike( is too low to
band IgM/IgA) with one light quantify or to call it a definite M band. Such suspected cases of
chain Kappa/Lambda unknown significance MGUS, Smouldering myeloma) requires follow
ups in 3-6months. This pattern may also be a case of myeloma on
therapy.
M band/distinct/Thin distinct Either Kappa/Lambda 1. Light chain disease, suggest urine Immunofixation 2. IgD or IgE
band chain only, no heavy disease 3. Multiple bands in lambda indicate polymerised form
chain band
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

Distinct/thin distinct band Only heavy chain with no Heavy chain disease should be ruled out. Suggested Immunoselection.
apparent light chain
Very thin distinct band Only heavy chain with no Cryoglobulin
apparent light chain
2 M band/ 2 distinct band 2 band with same or 1. Biclonal Gammopathy 2. Paraprotein (monomer / polymer of
different heavy chain and Immunoglobins)
2 band with same or
different light chain.
A diffuse band in gamma One or more heavy chain Usually indicates a polyclonal gammopathy e.g. TB, gamma globulin
globulin with both light chain with both light chains Hepatitis, SLE, AIDS, and some autoimmune
(kappa/Lambda) region (K and L) bands disorders.
Thin / Very thin distinct band One heavy chain with one The free light chain is to assess renal function. A urine immunofixation
light chain and different electrophoresis is recommended to know if there are free light in the
free light chain. urine or even worse if there are heavy chains. Light chains are an
indication that the tubules are malfunctioning.

Dr. Shivani Sharma Dr. Deepthy Sahadevan

DCP, DNB, DipRCPath. Ph. D.
Reg. No. 1906
Page 5 of 7
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:27
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
Multiple Myeloma Comprehensive Panel Quantitative, Serum
Parameters Result Unit Biological Reference Interval
Protein Electophoresis
Total Proteins L 5.71 g/dL 6.0 - 8.3

Albumin 3.71 g/dL 3.57-5.42

Gel Electrophoresis
Alpha 1 Globulin L 0.15 g/dL 0.19-0.40
Gel Electrophoresis
Alpha 2 Globulin 0.86 g/dL 0.45-0.96
Gel Electrophoresis
Beta Globulin H 0.71 g/dL 0.30-0.59
Gel Electrophoresis
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

Gamma Globulin L 0.27 g/dL 0.71-1.54

Gel Electrophoresis
Albumin/Globulin Ratio 1.85 Ratio 1.0-2.2
Calculated
“M” Band See Interpretation Absent

INTERPRETATION Kindly see serum immunofixation report.

Dr. Shivani Sharma Dr. Deepthy Sahadevan

DCP, DNB, DipRCPath. Ph. D.
Reg. No. 1906
Page 6 of 7
 UNIQUE PATIENT ID: 119606
Case ID : 24070003485 Report Status : Final Regn Date : 22-Jul-2024 17:50
Patient Name : Mr. RAMASWAMY NAIDU B Collected On : 22-Jul-2024 17:50
MH010763869
Age/DOB/Sex : 75 Years / / Male Reported On : 24-Jul-2024 16:27
Physician Name : Dr. Satish Kumar. Processed At : CORE-Gurugram.
Ref No. : Sample Type : Serum
Hospital Name : manipal Hospital , Yeswanthpur
24070003485-Mr. RAMASWAMY NAIDU B MH010763869-75 Years-Male

Dr. Shivani Sharma Dr. Deepthy Sahadevan

DCP, DNB, DipRCPath. Ph. D.
Reg. No. 1906
Page 7 of 7