First stage
No.           المادة                              Lecture title                        Hours
                                                 Biology                                2
                                                  Cell                                  2
                                      Tissues, bone and cartilages                      3
                                  Nervous system (central & peripheral)                 4
                                                Nutrition                               2
                                  Digestive system (Mouth, Esophagus,
                                                                                        2
                                                Stomach)
1        Human Biology                Digestive system (intestine)                      1
                                     Excretory system & respiration                     3
                                 Human genetics (chromosomes & semi-
                                                                                        3
                                              lethal genes)
                                                  Skin                                  2
                                           Circulatory system                           3
                                Immunity (Inflammation, immunity & the
                                                                                        3
                                      blood , immunity to disease)
                                    Some fundamentals of measurements and
                                                                                        4
                                                calculations.
                               Interpretation of prescription or medication orders.     4
      Principles of Pharmacy                   The metric system.                       4
 2
              Practice                        Calculation of doses.                     4
                                        Reducing and enlarging formulas.                4
                                  Density, specific gravity and specific volume.        4
                                    Percentage and ratio strength calculation.          6
                                   Review of elementary concept important to
                               analytical chemistry: Strong and weak electrolytes;       4
                                    important weight and concentration units.
                                 The evaluation of analytical data: Definition of
                                                                                         1
                                                       terms.
 3    Analytical Chemistry      An introduction to gravimetric analysis: Statistical
                                 analysis of data; rejection of data; precipitation      9
                                           methods; gravimetric factor.
                                The scope of applications of gravimetric analysis:
                               Inorganic precipitating agents; organic precipitating     4
                                                      agents.
                         An introduction to volumetric methods of analysis:
                          Volumetric calculations; acid-base equilibria and     5
                                            pH calculations.
                        Buffer solutions: Theory of neutralization titrations
                                                                                3
                                           of simple system.
                            Theory of neutralization titrations of complex
                                                                                5
                                    system; Precipitation titrations.
                         Calculation of pH in complex system; Volumetric
                                                                                4
                                  methods based on complex system.
                         Equilibria in oxidation-reduction system; theory of
                                                                                6
                                     oxidation-reduction titrations.
                          Spectrophotometric analysis: An introduction to
                           optical methods of analysis; Methods based on        4
                                        absorption of radiation.
                           General concept: Information technology (IT);
                                           Computer systems
                                                                                3
                           (hardware, software, user); types of computers;
                                      major parts of the computer
                           Hardware: Hardware; input and output devices;
                                         central processing unit                4
                                                 (CPU).
                        Memory, storage media and performance: Memory;
                                            kind of memory
                         (RAM, ROM, cache memory, flash memory); data
                                                                                6
                              representation in memory; storage devices
                            (secondary storage); kind of storage devices;
                                        computer performance.
                           Computer software: Software (system software,
                                         application software);
4   Computer Sciences           programming languages; generation of
                             programming languages (machine language,
                               assembly language, high level language,
                               application generators, objective oriented       6
                           language); compiler and interpreters; operating
                          systems (O.S ); function and type of O.S; type of
                             software according to source; (commercial,
                         shareware, freeware and public domain); interface,
                                  multimedia; system development.
                               Data Communication and network: Data
                                      communication; work group
                          computing; type of networks; local area network
                        (LAN); wide area network (WAN ); WAN Devices            5
                         (HUB, router, get way, bridge, repeater); networks
                              topologies; data communication hardware;
                                               protocols.
                               The internet: Internet development; using the
                                          internet; internet services;
                           search engines; electronic mail; general concept of
                                                                                     6
                           internet; viruses and type of virus; protection from
                             virus; security system and information security;
                                    data protection act; computer crimes.
                             Mathematics: General concepts; coordinate and
                                                graph in plane;
                            inequality; absolute value or magnitude; function        6
                                               and their graphs;
                          displacement function; slope and equation for lines.
                            Limits and continuity: Limits; theorem of limits;
                                                limit involving                      4
                                 infinity; continuity; continuity conditions.
5                                Derivatives: Line tangent and derivatives;
                                             differentiation rules;
                                                                                     6
                               derivative of trigonometric function; practice
                                                    exercises.
                          Integration: Indefinite integrals; rules for indefinite
                                             integrals; integration
                           formulas for basic trigonometric function; definite       6
                            integrals; properties of definite integrals; practice
                                                    exercises.
                                Biostatistics: General concepts of statistics;
                                              statistical methods;
      Mathematics and                                                                2
                               statistical theory; applied statistics; statistical
       Biostatistics                               operations.
                           Probability concepts: Properties of probability; Set
                                                 theory and set
                              notation (basic notation); counting techniques-
                             permutations and combinations; calculating the
                                                                                     6
                          probability of an events; probability distribution of
                             discrete variable; binomial distribution, Poisson
                           distribution; continues probability distribution and
                          normal distribution, review questions and exercises.
                            The concept of central tendency: Mean of sample
                                                  and mean of
                                                                                     6
                              population; median; mode; measure of central
                                 tendency; review questions and exercises.
                          Deviations and variation: Deviation; dispersion and
                                              variability; standard
                             deviation and variance; coefficient of variations;
                              standard error; correlation analysis.(regression       9
                          model and sample regression equation); application
                            of statistic in medical field; review questions and
                                                    exercises.
    Medical Terminology         Basic word roots and common suffixes                 1
                     More word roots, suffixes and prefixes related to
                    pharmaceutical sciences (pharmacognosy, clinical        1
                           pharmacy, pharmaceutics,…etc)
                     Basic anatomical terms and abnormal conditions         2
                               The genitals and urinary tract               1
                                 The gastrointestinal tract                 1
6                          The heart and cardiovascular system              1
                    Symptoms, diagnoses, treatments, communication
                                                                            2
                               qualifiers, and statistics
                     Growth and development, and body orientation           1
                          Gynecology, pregnancy, and childbirth             1
                             The eye and the respiratory tract              1
                      The nervous system and behavioral disorders           2
                                   Blood and immunity                       1
                                    Circulatory system:
                       Location of vascular system (Heart, Arteries,        1
                                            Veins)
                                    Circulatory system:
                        Location of lymphatic system (Lymphatic             1
                                         capillary).
                                     Lymphoid tissue:
                     location of the (Thymus gland, Spleen & Lymph          1
                                            nodes)
                           Lymphoid nodule (MALT) & Tonsils                 1
                                      Nervous system:
                                                                            1
                     Central & Peripheral nervous system by location
7   Human Anatomy                   Respiratory system:
                    -Conducting portion (Nose, Nasopharynx, Trachea
                                                                            1
                                 Bronchus & Bronchioles).
                                -Respiratory portion (Lung)
                                     Digestive system:
                    -location of different parts of digestive tract (GIT)
                       (Oral cavity, Mouth, Esophagus & Stomach)            2
                    -Small intestine, Large intestine, Rectum & Anus.
                                    Digestive system:
                      Glands associated with the digestive tract by         1
                    location (Salivary glands, Pancreas, Liver & Gall
                                         bladder).
                                       Endocrine system:
                                 -location of the pituitary gland             1
                      -location of the Adrenal, Thyroid, Parathyroid, Islet
                                of Langerhans & Pineal glands.
                                  Male reproductive system:
                                                                              2
                                      -location of the testes.
                                     -Excretory genital ducts
                          -Excretory genital glands (Seminal vesicles,
                                  Prostate & Cowper's glands)
                                 Female reproductive system:
                                                                              2
                        -location of ovary, Oviduct, Uterus & Vagina.
                                         Urinary system:
                                                                              1
                              -location of the (kidney & nephrone)
                         - location of the (Ureter, Bladder & Urethra).
                        Dilution and concentration of pharmaceutical
                                                                              10
                                           preparations.
    Pharmaceutical                      Isotonic solutions.                   6
8   Calculations by    Electrolyte solutions (milliequivalents, millimoles
       Stoklosa                                                               6
                                        and milliosmoles).
                      Constituted solutions, I.V admixtures and flow rate
                                                                              8
                                           calculations.
                            General concepts: Method of physics and
                                   standards; thermodynamics
                         system and system properties; conservation of        3
                                         energy principle;
                        application of thermodynamics; the Zeroth law.
                          Pressure; temperature and temperature scales
                                      (Celsius, Fahrenheit,
                        Kelvin); equation of state; ideal gas and real gas;
                       general law of gases; clauses equation and Vander
                                                                              6
                           Waales equation; equilibrium and types of
                       equilibrium; compressibility factor, coefficient of
9   Medical Physics        volume expansion, elastic coefficient (bulk
                                            modulus).
                        Heat and energy; work and mechanical forms of
                                       work; power; the 1st
                                                                              3
                       law of thermodynamics; Boyles and Charles law;
                                        practice exercises.
                         The 2nd law of thermodynamics; reversible and
                                       irreversible process;
                      entropy and enthalpy; internal energy; heat capacity
                                                                              6
                           and adiabatic process; the relation between
                         pressure, volume, and temperature in adiabatic
                                             process.
                            Fundamental of physics: Kinetic theory of a gas;
                                         electromagnetic waves;                   6
                                  Maxwell equations; physical optics.
                              Radiation: Kirshoffs law; planks law; Stefan-
                                       Boltzman law; Wiens law;
                                                                                  6
                            Black body and Albedo; Heat transfer (radiation,
                                        convection, conduction).
                           Production of X-Ray and X-Ray spectra; absorption
                                           of X-Ray; U.V and
                                                                                  3
                              IR effects; medical and biological effects of
                                         radiation; radiotherapy.
                                              Introduction.                       3
                                          Alkanes and methane.                    6
                                             Alkenes I and II                     5
                                           Alkynes and dienes.                    5
10   Organic Chemistry I
                                          Stereochemistry I & II                  8
                                           Alcohols and ethers.                   8
                                             Alkyl halides.                       6
                                              Cycloalkanes.                       4
                                          Circulatory system:
                              Structure of the vascular system (Heart wall,       2
                                     Arteries, Veins & Capillaries)
                                          Circulatory system:
                             Structure of the lymphatic system (Lymphatic         1
                                                capillary).
                                            Lymphoid tissue:
                           Structure & function of the (Thymus gland, Spleen      1
                                            & Lymph nodes)
                                  Lymphoid nodule (MALT) & Tonsils                1
                                            Nervous system:
                                                                                  3
                                  Central & Peripheral nervous system
11       Histology
                                          Respiratory system:
                           -Conducting portion (Nose, Nasopharynx, Trachea
                                                                                  3
                                       Bronchus & Bronchioles).
                                      -Respiratory portion (Lung)
                                            Digestive system:
                                             -Digestive steps.
                             -General structure of the digestive tract (GIT)      3
                              (Oral cavity, Mouth, Esophagus & Stomach)
                           -Small intestine, Large intestine, Rectum & Anus.
                                            Digestive system:
                           Glands associated with the digestive tract (Salivary   1
                                glands, Pancreas, Liver & Gall bladder0.
                Endocrine system:
      -General structure of the pituitary gland        2
     -Histophysiologies of the pituitary gland.
                Endocrine system:
    -General structure of the Adrenal, Thyroid,        2
 Parathyroid, Islet of Langerhans & Pineal glands.
             Male reproductive system:
           -General structure of the testes.           2
             -Stages of spermatogenesis.
             Male reproductive system:
 -Excretory genital ducts-Excretory genital glands     1
   (Seminal vesicles, Prostate & Cowper'sglands)
            Female reproductive system:
   -General structure of ovary, Oviduct, Uterus &
                       Vagina.                         3
           -Stages of follicle development.
                      -Ovulation
                   Urinary system:
 -Structure & Function of the (kidney & nephrone)
-Histology of the nephrone (filtration, absorption &   3
                      excretion).
   - Structure of the (Ureter, Bladder & Urethra).
                       The skin
                                                       2
                        Thick & Thin skin
                                               Second stage
           المادة                                    Lecture title
                                                                                                hours
                           Aromatic Hydrocarbons (includes benzene, electrophilic aromatic       10
                           substitution, arenas and their derivatives).
                    Carboxylic acids: properties and reactions.                                   5
  Organic Chemistry Functional derivatives of carboxylic acids.                                   7
1
          II
                     Amines I and II.                                                             6
                    Aldehydes and ketones (include also aldol and Claisen
                    condensation); Classification, reactions and properties.                     12
                           Phenols.                                                               5
                           Importance of microbiology, History of microbiology
                                                                                                  2
                           Anatomy of bacteria: Surface appendage, Capsule, Cell wall of
                           G.+ve & G –ve bacteria, Cytoplasmic membrane.                          2
                           Bacterial physiology: Physical and chemical growth determinate,
                           growth and growth curves, bacterial reproduction.                      2
                           Genetics: Definition, genetic, element, mutation (spontaneous,
                           gene                                                                   2
                           transfer, transformation, conjugation, and gene transduction).
                           Recombinant DNA biotechnology.
                                                                                                  2
                           Sporulation and germination.
                                                                                                  2
   Medical Microbiology,
                           Sterilization (chemical + physical Methods).
                                                                                                  2
                           Chemotherapy.
                                                                                                  2
                           Morphology of Bacteria, Staining and Classification.
                                                                                                  1
                           Staphylococci species: Streptococcus pyogenes; Streptococcus
                           pneumoniae                                                             3
                           Aerobic Spore-forming bacteria Bacillus species ( B. anthracis, B.
                           subtilis, B. ceseus).                                                  1
                           Clostridium perfringens; Clostridium tetani; Clostridium botuliun
                                                                                                  3
                 Corynebacterium diphtheriae
                                                                                        1
                 Propionibacterium acnes, Listeria
                                                                                        1
                 Mycobacterium tuberculosis; M. leprae
                                                                                        1
                 Chlamyadiae; Actinomycetes
                                                                                        2
                 Identification & classification of G -ve bacteria
                                                                                        1
                 Enterobacteriaceae: E. coli; Klebsiella spp.; Cilrobacte , Sertalia,
                                                                                        4
                 The general and cellular basis of medical physiology.                  5
                 Physiology of nerves and muscles: Nerve cells; excitation              16
                 and conduction; Properties
                 of mixed nerves; glia; neurotrophins; Nerve fiber types and
                 functions; Muscles: Skeletal muscle; smooth muscle; cardiac
                 muscle. Synaptic transmission: Reflexes; cutaneous, deep
                 and visceral sensations; alert behavior, sleep and electrical
                 activity of the brain; control of posture and movement;
                 higher function of the nervous system; central regulation of
                 visceral function; the autonomic nervous system.
: Physiology I
                 Respiration: Respiratory zones; Mechanics of respiration; air 8
                 volumes; respiratory
                 muscles; compliance of the lungs and chest wall; surfactants;
                 differences in ventilation and blood flow in deferent parts of
                 the lung; Dead space and uneven ventilation; Pulmonary
                 circulation: Pressure, volume and flow. Gas transport
                 between the lungs and tissue; Regulation of respiration:
                 Neural control of breathing;
                 Respiratory centers; Regulation of respiratory activity:
                 Chemical factors; non chemical factors; Respiratory
                 adjustment in health and disease; Effect of exercise;
                 Hypoxia; Emphysema; Asthma.
                      Renal Physiology: Introduction; innervations of the renal         8
                      vessels; renal clearance;
                      renal blood flow; glomerular filtration rate (GFR):
                      Measurements; factor affecting GFR; Filtration fraction;
                      reabsorption of Na+, Cl – and glucose. Tubuloglomerular
                      feedback and glomerulotubular balance; water excretion in:
                      proximal tubules; loop of henle; distal tubules; collecting
                      ducts; the counter current mechanism; role of urea; water
                      diuresis and osmotic diuresis; acidification of the urine: H+
                      secretion; reaction with buffers; ammonia secretion; factors
                      affecting acid secretion; bicarbonate execration; regulation
                      of Na+, K+ and Cl – excretion; uremia; acidosis; micturition.
                      Cardiovascular system: origin and spread of cardiac               8
                      excitation; the electrocardiogram;
                      cardiac arrhythmias; electrographic findings in cardiac
                      diseases; mechanical events of the cardiac cycle; cardiac
                      output; cardiovascular regulatory mechanisms: Local
                      regulatory mechanisms; systemic regulation by the nervous
                      system; systemic regulation by hormones; Coronary
                      circulation; Hypertension; Heart failure; Angina pectoris.
                      States of matter, binding forces between molecules, gases,        10
                      liquids, solid
                      and crystalline matters; phase equilibria and phase rule;
                      thermal analysis.
                      Thermodynamics, first law, thermochemistry, second law,           8
                      third law,
                      free energy function and applications.
                      Solutions of non-electrolytes, properties, ideal and real         7
                      colligative
                      properties, molecular weight determination.
                      Solution of electrolytes, properties, Arrhenius theory of         5
Physical Pharmacy I
                      dissociation,
                      theory of strong electrolytes, ionic strength, Debye-Huchle
                      theory, coefficients for expressing colligative properties.
                      Ionic equilibria, modern theories of acids, bases and salts,      8
                      acid-base
                      equilibria, calculation of pH, acidity constants, the effect of
                      ionic strength and free energy.
                      Buffered and isotonic solutions: Buffer equation; buffer          7
                      capacity;
                      methods of adjusting tonicity and pH; buffer and biological
                      system.
                      Patient-Centered Communication in Pharmacy Practice               2
                   Principles and Elements of Interpersonal Communication        2
Communication
                   Nonverbal type of communication.                              2
   Skills
                   Barriers to communication.                                    2
                   Listening and empathic responding during communication.       2
                   Assertiveness.                                                2
                   Interviewing and assessment.                                  2
                   Helping patients to manage therapeutic regimens.              2
                   Patient counseling; counseling check list; point-by-point
                   discussion;                                                   2
                   counseling scenario.
                   Medication safety and communication skills.                   2
                   Strategies to meet specific needs.                            2
                   Communicating with children and elderly about
                                                                                 2
                   medications.
                   Communication skills and inter-professional collaboration.    2
                   Electronic communication in healthcare.                       2
                   Ethical behavior when communicating with patients.            2
                   Heterocyclic system: Classes of heterocyclic systems;
                   general structures; properties; Occurrence in nature and in       5
                   medicinal products.
                   Five-membered ring heterocyclic compounds: pyrrole; furan
                   and thiophen.                                                     3
                   Source of pyrrole, furan and thiophen.                            2
    Organic        Electrophilic substitution in pyrrole, furan and thiophen:
  ChemistryIII     Reactivity and orientation.                                       5
                   Six-membered ring heterocyclic compounds: Structure &
                   reactions of pyridine.                                            4
                   Saturated five-membered heterocyclic compounds.                   6
                   Heterocyclic of five & six member rings with two & three
                                                                                     5
                   heteroatoms.
                   Introduction.                                                 3
                   Intestinal protozoa (Amoeba, Balantidium, Giardia,            5
Medical Virology   Chilomastix)
and Parasitology   Haemoflagellates: Leshmania spp.; Trypanosome spp.            4
                   Sporozoa: Malarial parasites of human; Toxoplasma.            4
                        Helminthes: Classification, Flukes: Hepatic flukes, Blood           10
                        flukes
                        (Schistosoma spp).Tap worms: Taenia spp., Echinococcus
                        (Hydatid cyst).Nematods: Ascaris, Entrobius.
                        Virology: Introduction, Comparison between viruses and              16
                        bacteria and
                        other microbes; Classification of viruses; Replication;
                        Chemotherapy; Herpes viridae; Orthomyxo viruses;
                        Paramyxo viruses; Retro viruses; Hepato viruses; Oncogenic
                        viruses.
                        Solubility and distribution phenomena, solvent-solute               10
                        interactions,
                        solubility of gases in liquids, solubility of liquids in liquids,
                        solubility of non-ionic solids in liquids, distribution of
                        solutes between immiscible solvents.
                        Complexation, classification of complexes, methods of               5
                        analysis,
                        thermodynamic treatment of stability constants.
                        Kinetics, rate and orders of reactions, influence of                9
                        temperature and other
                        factors on reactions rate, decomposition of medicinal agents
                        and accelerated stability analysis.
                        Interfacial phenomena, liquid interfaces, surface free energy,      5
                        measurement of interfacial tension, spreading coefficient,
Physical PharmacyII     surface active agents and wetting phenomena.
by Alfred Martin et a
                        Colloids, dispersed system and its pharmaceutical                   5
                        application, types of
                        colloidal systems, kinetic properties, diffusion, zeta
                        potential, solubilization.
                        Micrometrics, particle size, methods of determining particle        3
                        size,
                        particle shape and surface area, porosity, density.
                        Rheology, Newtonian systems, thixotropy measurement,                5
                        negative
                        thixotropy, determination of thixotropy.
                        Polymer science, definitions pharmaceutical applications,           3
                        molecular
                        weight averages.
                  Gastrointestinal function: Digestion and absorption of       10
                  carbohydrates;
                  proteins; lipids; absorption of water and electrolytes;
                  vitamins and minerals; regulation of gastrointestinal
                  function: Introduction; gastrointestinal hormones; mouth and
                  esophagus; stomach; exocrine portion of the pancreas; liver
                  and biliary system; small intestine; colon.
                  Circulatory body fluid: Introduction; blood; bone marrow;    15
                  white blood cells; immunity; platelets; red blood cells;
                  anemia; polycythemia; blood group and Rh factor;
 Physiology II
                  hemostasis: The clotting mechanism / blood coagulation
                  tests; anti clotting mechanism; the plasma; the lymph;
                  abnormalities of hemostasis.
                  Endocrinology: Introduction; energy balance, metabolism          20
                  and nutrition;
                  the pituitary gland; the thyroid gland; the gonads:
                  development and function of the reproductive system; the
                  adrenal medulla and adrenal cortex; hormonal control of
                  calcium metabolism and the physiology of the bone;
                  endocrine functions of the pancreas and regulation of
                  carbohydrate metabolism.
                  General Introduction: The Scope of Pharmacognosy,                     3
                  definitions and basic principles.
                  Drugs from natural sources, crud drugs, official and non-             1
                  official drugs.
                  Classification of natural products.                                   2
                  Plant nomenclature and taxonomy.                                      2
                  Production of crude drugs: Cultivation, collection, drying            3
                  and storage.
                  Deterioration of crude natural products.                              1
                  Chemistry of natural drug products.                                   3
                  Quality control: Evaluation of natural products;                      4
Pharmacognosy I
                  macroscopical evaluation; physical evaluation; chemical
                  evaluation; biological evaluation; spectroscopical evaluation.
                  Phytochemical investigation of herbal products: Extraction            4
                  of the plant material; Separation and isolation of
                  constituents; characterization of the isolated compounds.
                  Separation technique: Introduction; Mechanisms of                     15
                  separation and classification based on the type of technique;
                  paper chromatography; Thin layer chromatography; Ion-
                  exchange chromatography; Gel filtration chromatography;
                  Column chromatography; Gas chromatography; HPLC;
                  Electrophoresis; Affinity chromatography.
                  Traditional plant medicines as a source of new drugs.                 3
                  Bioassay-guided fractionation
                       Tissue culture of medicinal plant: Introduction and history;      4
                       laboratory of the plant tissue culture; aseptic techniques
                       Application of the plant tissue culture; environmental and
                       biological control; plant growth regulators.
                                         Third stage
     المادة                                   Lecture title
                                                                                         hours
                 Atomic and molecular structure/ Complexation.                               6
                 Essential and trace ions: Iron, copper, sulfur, iodine.                     3
                 Non essential ions: Fluoride, bromide, lithium, gold, silver and
                                                                                             2
                 mercury.
                 Gastrointestinal agents: Acidifying agents.                                 1
   Inorganic     Antacids.                                                                   2
Pharmaceutical
                 Protective adsorbents.                                                      1
  Chemistry
                 Topical agents.                                                             2
                 Dental agents.
                                                                                             1
                 Radiopharmaceutical preparations.                                           6
                 Radio opaque and contrast media.                                            6
                 Introduction: General biosynthesis pathways of secondary
                 metabolites.                                                                2
                 Carbohydrates.
                                                                                             2
                 Glycosides: Biosynthesis, physical and chemical properties; cardiac
                 glycosides; saponin glycosides; anthraquinone glycosides; flavonoid
                 glycosides; cyanophore lycosides.                                           5
Pharmacognosy
      II
                 Glycosides: Isothiocyanate glycosides; aldehyde glycosides; alcoholic
                 glycosides; phenolic glycosides; lactone glycosides; coumarins and          5
                 chromones.
                 Resins and resin combination; tannins.
                                                                                             2
                 Lipids: fixed oils and waxes.
                                                                                             3
                  Volatile oils: Introduction; chemistry of volatile oils; biosynthesis of
                  volatile oils; hydrocarbons as volatile oils; alcohols as volatile oils;        4
                  aldehydes as volatile oils.
                  Ketones as volatile oils; Phenols as volatile oils; Oxides as volatile
                  oils; Ester as volatile oils; Phenolic ethers as volatile oils.                 3
                  Non- medicinal toxic plants.
                                                                                                  2
                  Vitamins and Amino acids.
                                                                                                  2
                  Dispersed systems: their classification; comparisons between                2
                  different systems.
                  Solutions and types of solutions.                                           2
                  Solubility: Factors affecting solubility; expression of dissolution;        4
                  dissolution rate versus solubility; preparation of solutions containing
                  non-volatile materials.
                  Official solutions; classification of official solutions; preparation and   4
                  uses.
                  Aqueous solutions containing aromatic principles; aromatic waters;          4
                  methods of preparations; stability.
Pharmaceutical    Syrups: sugar based syrups; artificial and sorbitol based syrups;           4
 Technology I     stability of syrups.
                  Definition and methods of clarification; filter aids in clarification.      3
                  Preparation of solutions using mixed solvent systems; spirits, and          3
                  elixirs.
                  Extraction; maceration and percolation.                                     3
                  Tinctures; fluid extracts; extracts of resins and oleoresins.               4
                  Colloidal dispersions; lyophilic; lyophobic.                                6
                  Coarse dispersion; suspensions.                                             6
                  Introduction to the macromolecules biochemistry: Definitions and            2
                  terms; proteins, enzymes, DNA; Clinical value.
                  Amino acids: Structures of A.A (table of standard A.A abbreviation          3
                  and
 Biochemistry I   side chain); Classification, properties, isomerism.
                  Amino acids: Chemical reactions, Zwitter ions, titration curve
                  calculating isoelectric point values. Examples and questions. Non
                  standards A.A: Structures, existence and clinical value.                    3
Peptides: Peptide bond, resonance forms, isomers, physical properties
and chemical reactions. Essential poly peptides in human body,              3
structures, roles and clinical values.
Proteins: Structure and conformations of proteins, Primary structure,
Secondary structure (4 helix, 5 sheet), tertiary structure, quaternary
structure. Classification, synthesis, cellular functions (Enzymes, cell     3
signaling, and ligand transport, structural proteins), protein in
nutrition.
Denaturation of proteins and protein sequencing: Determining A.A            3
composition, N- terminal A.A analysis, C- terminal A.A analysis,
Edman degradation, prediction protein sequence from DNA/ RNA
sequences. Methods of protein study: Protein purification, cellular
localization, proteomics and bioinformatics, structure predication and
simulation.
Carbohydrates: Chemistry and classification, biomedical importance,         3
classification of CHO, Stereochemistry of monosaccharides,
metabolism of CHO; Physiologically important monosaccharides,
glycosides, disaccharides, polysaccharides.
Lipids: Introduction, classification of lipids, fatty acids (F.A),          3
nomenclature of F.A, saturated F.A, unsaturated F.A, physical and
physiological properties of F.A, metabolism of lipids. Phospholipids,
lipid peroxidation and antioxidants, separation and identification of
lipids, amphipathic lipids.
Enzymes: Structures and mechanism, nomenclature, classification,            3
mechanisms of catalysis, thermodynamics, specificity, lock and key
model, induced fit model, transition state stabilization, dynamics and
function, allosteric modulation. Biological function, cofactors,
coenzymes, involvement in disease.
Kinetics: General principles, factors effecting enzyme rates (substrate     2
conc., pH, temperature, etc), single-substrate reaction (Michaelis-
Menten kinetics), kinetic constants. Examples of kinetic questions
and solutions.
Enzyme inhibition: Reversible inhibitors, competitive and non               1
competitive inhibition, mixed-type inhibition, Irreversible inhibition.
Inhibition kinetics and binding affinities (ki), questions and solutions.
Control of activity and uses of inactivators; multi-substrate reactions,    1
ternary-complex mechanisms, ping-pong mechanisms, non-
Michaelis- Menten kinetics, pre-steady-state kinetics, chemical
mechanisms.
Nucleic Acid: Chemical structure, nucleic acid components, nucleic          3
acid bases, nucleotides and deoxynucleotides (Properties, base
pairing, sense and antisense, super-coiling, alternative structures,
quadruple structures.
                  Biological functions of DNA: Genes and genomes, transcription and     2
                  translation, replication.
                  Biochemistry of extracellular and intracellular communication:        3
                  Plasma
                  membrane structure and function; Biomedical importance, membrane
                  proteins associated with lipid bilayer, membranes protein
                  composition, dynamic structures of membranes, a symmetric
                  structures of membranes.
                  Artificial membranes model, the fluid mosaic model, membrane          1
                  selectivity, physiological functions of plasma membranes.
                  Biochemistry of the endocrine system: Classification of hormones,     3
                  biomedical importance, the target cell concept and hormone
                  receptors, biochemistry of hormone signal transduction.
                  Special topics: Nutrition, digestion, and absorption. Biomedical      3
                  importance, digestion and absorption of carbohydrates, lipids,
                  proteins, vitamins and minerals; energy balance. Biochemistry of
                  hemostasis and clot formation.
                  Introduction.                                                             1
                  Cell injury and tissue response; Degeneration; Necrosis; Atrophy;         6
                  Hypertrophy; Metaplasia and Calcification; Inflammation and Repair.
                  Disorders of electrolytes and water and acid–base balances: Hyper         4
                  and
                  Hyponatremia; Hyper and Hypokalemia; Syndrome of inappropriate
                  secretion of ADH; Diabetes insipidus; Metabolic acidosis and
                  alkalosis; Respiratory acidosis and alkalosis.
                  Disorders of cardiovascular system: Hyperemia; Congestion and             5
                  edema;
Pathophysiology   Thrombosis; embolism and infarction; Shock; Coronary heart disease
                  and MI; Rheumatic heart disease; Heart failure; Acute pulmonary
                  edema; Essential hypertension; Secondary hypertension; Malignant
                  hypertension; Hypotension; Aneurysm versus varicose veins;
                  Disorders of respiratory system: Pneumonias; Tuberculosis;                3
                  Respiratory
                  distress syndrome; Bronchial asthma; Emphysema and
                  bronchiectasis; Cystic fibrosis; Pulmonary embolism; Pulmonary
                  hypertension.
                  Disorders of the renal system: Nephrotic syndrome;                        4
                  Glomerulonephritis;
                  Diabetic glomerulosclerosis; Hypertensive glomerular disease;
                  Pyelonephritis; Drug related nephropathies; Acute renal failure;
                  Chronic renal failure.
                 Disorders of GI and hepatobiliary systems: Peptic ulcer and Zollinger    4
                 –
                 Ellison syndrome; Irritable bowel syndrome; Crohn's disease;
                 Diarrhea; Celiac disease; Viral hepatitis; Primary biliary cirrhosis;
                 Liver failure; Cholelithiasis.
                 Disorders of thyroid function: Hypothyroidism.Hyperthyroidism.           2
                 Graves’s disease.Thyrotoxicosis.
                 Disorders of adrenal function: Cushing syndrome. Adrenal cortical        2
                 insufficiency (primary and secondary). Congenital adrenal
                 hyperplasia. Pheochromocytoma.
                 Diabetes mellitus and metabolic syndrome; Dyslipoproteinemia.            5
                    Drug distribution.                                                    4
                    Acid- base properties.                                                3
                    Statistical prediction of pharmacological activity.                   3
                   QSAR models.                                                           2
                   Molecular modeling (Computer aided drug design).                       1
                   Drug receptor interaction: force involved.                             1
                   Steric features of drugs.                                              2
   Organic
Pharmaceutical     Optical isomerism and biological activity.                             1
 Chemistry I
                   Calculated conformation.                                               1
                   Three- dimensional quantitative structure activity relationships and   1
                 databases.
                   Isosterism.                                                            1
                   Drug-receptor interaction and subsequent events.                       1
                    General pathways of drug metabolism: Sites of drug                    22
                 biotransformation; Role of cytochrome P450 mono-oxygenases in
                 oxidative biotransformation; Oxidative reactions; Reductive
                 reactions; Hydrolytic reactions; Phase II reactions.
                   Factors affecting drug metabolism.                                     2
                 General introduction to Pharmacology.                                    2
                 Pharmacokinetics.                                                        4
pharmacology I
                 Drug Receptor interaction and Pharmacodynamics.                          4
                 The autonomic nervous system (ANS).                                      2
                   Cholinergic system.                                                     6
                   Adrenergic system.                                                      6
                   Principal of antimicrobial therapy.                                     2
                   β- lactam and other cell wall synthesis inhibitor antibiotics           4
                   Protien synthesis inhibitors                                            4
                   Quinolones, Folate antagonists, and urinary tract antiseptics.          3
                   Antimycobacterium drugs                                                 2
                   Antifungal drugs.                                                       2
                   Antiprotozoal drugs.                                                    1
                   Anthelmintic drugs.                                                     2
                   Antiviral drugs.                                                        1
                   Emulsions; purpose of emulsification; methods of emulsification;       10
                   emulsifying agents; HLB system; stability of emulsions.
                   Lotions; liniments and collodions.                                     5
                   Suppositories.                                                         6
Pharmaceutical
Technology II      Powdered dosage forms.                                                 10
                   Semisolid dosage forms.                                                10
                   Incompatibilities in pharmaceutical dosage forms.                      4
                   Bioenergetics.                                                     2
                   Biologic oxidation.                                                2
                   The respiratory chain and oxidative phosphorylation.               2
                   Over view of metabolism.                                           2
                   Citric acid Cycle.                                                 2
 Biochemistry II
                   Glycolysis.                                                        2
                   Metabolism of glycogen.                                            4
                   Gluconeogenesis.                                                   3
                   Pentose phosphate pathway and other pathways of hexose             3
                   metabolism.
                   Biosynthesis of fatty acids.                                       3
                    Oxidation of fatty acids.                                                2
                    Metabolism of acylglycerol and sphingolipids.                            2
                    Lipid transport and storage.                                             2
                    Cholesterol synthesis, transport, and excretion.                         2
                    Biosynthesis of the Nutritionally Nonessential Amino Acids.              3
                    Catabolism of Proteins & of Amino Acid Nitrogen                          3
                    Catabolism of the Carbon Skeletons of Amino Acids.                       2
                    Conversion of Amino Acids to Specialized Products.                       2
                    Porphyrins & Bile Pigments                                               2
                    Alkaloids: Introduction; Physical and chemical properties; pyridine,         5
                    piperidine alkaloids; tropane alkaloids.
                    Alkaloids: Quinoline tropan alkaloids; iso-quinoline alkaloids;              5
                    imidazole alkaloids; indole alkaloids.
                    Alkaloids: Steroidal alkaloids; lupinane alkaloids; alkaloidal amines;       4
Pharmacognosy III
                    purine alkaloids.
                    Antibiotics: Natural sources; biosynthetic pathways, isolation and           6
                    purification.
                    .phytotherapy :Introduction , principles,medicinal plants in selected        10
                    health care systems.Important natural products & phytomecines used
                    in pharmacy & medicine
                    Introduction to Pharmacy Ethics (Theoretical considerations).                2
                    Code of Ethics for Pharmacists.                                              1
                    Common Ethical Considerations in Pharmaceutical Care Practice
                    (Beneficence, Autonomy, Honesty, Informed Consent,                           3
                    Confidentiality, Fidelity ………).
 Medical ethics     Interprofessional Relations.                                                 2
                    Making ethical decisions.                                                    1
                    Ethical issues related to clinical pharmacy research.                        1
                    Ethical problems in the pharmacist’s clinical practice.                      1
                    Preventing misuse of medicines.                                              1
                    Case studies in pharmacy ethics.                                             3
                                           Fourth stage
        المادة           Lecture title                                                         hours
                         Introduction to CNS pharmacology.                                     2
                         CNS stimulants.                                                       2
                         Anxiolytic and Hypnotic drugs.                                        3
                         General and Local Anesthetics.                                        3
                         Antidepressant drugs.                                                 3
                         Antipsychotic (neuroleptic) drugs.                                    3
                         Opioid analgesics and antagonists.                                    3
                         Treatment of neurodegenerative diseases.                              3
                         Antiepileptic Drugs.                                                  2
                         Diuretics.                                                            2
    Pharmacology II
                         The treatment of heart failure (HF).                                  2
                         Antiarrhythmic drugs.                                                 2
                         Antianginal Drugs.                                                    2
                         Antihypertensive drugs.                                               3
                         Drugs affecting the blood.                                            3
                         Antihyperlipidemic drugs.                                             2
                         Gastrointestinal and antiemetic drugs.                                2
                         Drugs acting on the respiratory system.                               3
                         Cholinergic agents, cholinergic receptors and their subtypes.             3
                         Cholinergic agonists; stereochemistry and structure-activity              5
                         relationships (SAR); products; cholinesterase inhibitors.
                         Cholinergic blocking agent; structure-activity relationships (SAR);       5
                         Solanaceous alkaloid and analogues; synthetic cholinergic
organic pharmaceutical
                         blocking agents and products; ganglionic blocking agents
      chemistry
                         (neuromuscular blocking agents).
                         Analgesic agents (SAR of morphine, SAR of meperidine type                 5
                         molecules; SAR of methadone type compounds; N-
                         methylbezomorphans, antagonist type analgesics in
                         benzomorphans).
                     Analgesic receptors, endogenous opioids; Products; Antitusive           5
                     agents; Anti-inflammatory analgesics.
                     Adrenergic agents (Adrenergic neurotransmitters); Adrenergic            8
                     receptors; Drugs affecting Adrenergic neurotransmission;
                     Sympathomimetic agents; Adrenergic receptor antagonists.
                     CNS depressant; Benzodiazepines and related compounds;                  7
                     Barbiturates; CNS depressant with skeletal muscle relaxant
                     properties; Antipsycotics; Anticonvulsants.
                     CNS Stimulants                                                          3
                     Steroidal & nonsteroidal hormones                                       4
                     Introduction to community pharmacy.                                     1
                     Respiratory problems: Cough, Common cold, allergic rhinitis,
                                                                                             3
                     Otitis media,          Laryngitis & Pharyngitis
                     G.I.T problemse: Diarrhea, Constipation, Heart burn and
                                                                                             4
                     indigestion, IBS and         Hemorrhoids
                     Pediatric care practice : Oral thrush, pinworms and head lice           2
                     Skin conditions: Acne, Scabies, Psoriasis, Hair loss, Fungal
                     infection, Eczema and Dermatitis , Dandruff, Cold sore, Corns           5
                     and Callus.
                     Women’s health care: Cystitis and vaginal thrush, primary
                     dysmenorrhea and                  Premenstrual syndrome.                2
Clinical Pharmacy1   CNS related problems: Headache, Insomnia, Motion sickness,
                                                                                             3
                     Nausea and vomiting
                     - Eye problems                                                          1
                     ENT problems                                                            1
                     Oral hygiene, mouth ulcer                                               1
                     Obesity and body weight control.                                        1
                     - Pain and musculoskeletal disorders                                    1
                     Nicotine replacement therapy ( NRT).                                    1
                     Dietary supplements                                                     1
                     An update in reclassification of OTC drugs ( simvastatin,
                                                                                             2
                     Tamusotisin & azithromycin).
                     Medication adherence and errors.                                        1
                     Introduction to biopharmaceutics.                                   2
                     Biopharmaceutic aspects of products; drug absorption;               6
Biopharmaceutics     mechanisms of
                     absorption; physicochemical factors; dissolution rate; effects of
                     excipients; type of dosage forms.
                One compartment open model.                       2
                Multicompartment models.                          2
                Pharmacokinetics of drug absorption.              2
                Bioavailability and bioequivalence.               2
                Clearance of drugs from the biological systems.   2
                Hepatic elimination of drugs.                     2
                Protein binding of drugs.                         2
                Intravenous infusion                              2
                Multiple dosage regimens.                         2
                Non-linear pharmacokinetics.                      2
                Dosage adjustment in renal diseases.              2
                General items &ICD10                                  2
                Predisposing factors of infectious diseases           1
                Cardiovascular diseases                               1
                Gastrointestinal diseases                             2
                Skin diseases                                         1
                -Sexually transmitted diseases                        1
                Oncogenic diseases                                    3
                Respiratory infections                                2
Public Health   Familyplaninig include maternal infections,
                                                                      2
                vaccination
                -Immunology
                General introduction                                  1
                innate &adaptive immunity                             2
                -antigen characteristics                              1
                B&Tcells                                              2
                complements                                           1
                Hypersensitivity types                                2
                          Oncogenic immunity                                                         3
                          -Auto immune diseases                                                      2
                          Immune deficiency diseases                                                 1
                          Hormones of the pituitary and thyroid glands.                          3
                          Insulin and oral hypoglycemic drugs.                                   4
                          Adreno-corticosteroids.                                                3
                          The gonadal hormones and inhibitors.                                   3
                          Autacoids and autacoid antagonists                                     3
   Pharmacology III       Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-         3
                          inflammatory agents.
                          Drugs used in erectile dysfunction.                                    2
                          Drugs used in osteoporosis.                                            2
                          Drugs used in the management of obesity.                               2
                          Cancer Chemotherapy: Anticancer drugs and                              5
                          immunosuppressants.
 Organic Pharmaceutical   β-Lactam antibiotics (Penicillins); β-Lactamase inhibitors;                9
     Chemistry III        Cephalosporins and Monobactams.
                          Aminoglycosides and Chloramphenicol; Tetracylines; Macrolides;             9
                          Lincomycins and Polypeptides; Antiviral agents (properties of
                          viruses, viral classification, products).
                          Sulfonamides (chemistry, nomenclature, mechanism of action,                4
                          resistance, toxicity, side effects, metabolism, protein binding,
                          distribution and SAR); products; Sulfones.
                          Anti-neoplastic agents: Alkylating agents; Antimetabolites;                17
                          Antibiotics; Plant products; Miscellaneous compounds.
                          Hormones and related compounds; Future anti-neoplastic agents;             6
                          Monoclonal antibodies; Gene therapy of cancer.
                          Introduction to the concept of clinical pharmacy- its activities and
                          professional           responsibilities.( including current state of       1
Clinical Pharmacy II      clinical pharmacy in Iraq) .
                          overview of pharmaceutical care practice (the patient care
                                                                                                     1
                          process).
                         Hematologic disorders: Anemia and sickle cell disease.                  2
                         Hypertension.                                                           2
                         Ischemic heart diseases                                                 2
                         Heart failure.                                                          2
                         Peripheral vascular diseases.                                           1
                         - Asthma.                                                               2
                         Chronic obstructive pulmonary disease ( COPD ).                         1
                         Diabetes mellitus & Diabetic ketoacidosis (DKA) .                       2
                         Peptic ulcer disease.                                                   2
                         Tuberculosis                                                            1
                         Infective meningitis                                                    1
                         Respiratory tract infections                                            2
                         GIT infections                                                          1
                         Gout and hyperuricemia                                                  1
                         Rheumatoid arthritis (RA) and osteoarthritis (OA)                       2
                         Osteoporosis and other metabolic bone disease.                          1
                         Infectious Endocarditis                                                 1
                         Surgical antibiotic prophylaxis                                         1
                         Urinary tract infection (UTI)                                           1
                         Introduction: general consideration; host factor, environmental     3
                         factors
                         of toxic effects.
                         Carcinogenesis.                                                     3
                         Mutagenesis:                                                        1
                         Target organs and systemic toxicology; Respiratory system, Liver,   16
General Toxicology       Kidney, Skin, Nervous system, cardiovascular system, Blood.
                         Toxic substances: Food additive and contaminants, Pesticides,       15
                         Metals,
                         Radiation and radio active materials, plants, Solvents,
                         Environmental toxicology: Air pollution, water and soil pollutants, 7
                         Gases (Tear gas, Pepper spray), CO, Cyanide(H2S).
                      Principles of pharmaceutical processing; mixing; fluid mixing;         7
                      flow
Industrial Pharmacy I characteristics; mechanisms of mixing; mixing equipments; batch
                      and continuous mixing; mixer selection; solid mixing theory and
                      particulate solid variables; forces and mechanisms.
                    Milling; pharmaceutical application; size measurement methods;          7
                    theory
                    and energy of commenution; types of mills; factors influencing
                    milling;
                    selection of mill techniques; specialized drying methods.
                    Drying: definition; purpose; humidity measurement; theory of            7
                    drying;
                    drying of solids, and classification of dryer; specialized drying
                    methods.
                    Clarification and filtration: Theory; filter media; filter aids;        7
                    selection of
                    drying method; non-sterile and sterile operations; integrity testing;
                    equipments and systems (commercial and laboratory).
                    Sterilization; validation of methods; microbial death kinetics;         7
                    methods
                    of sterilization (thermal and non-thermal); mechanisms;
                    evaluation.
                    Pharmaceutical dosage form design; pre-formulation; preliminary         3
                    evaluation; bulk characterization; solubility and stability analysis.
                    Pharmaceutical dosage forms; sterile products; development;             7
                    formulation; production; processing; quality control.
                                      Fifth stage
                 Lecture title
     المادة                                                                                 hours
                 Basic concept of prodrugs; Covalent bonds (cleavable); Prodrugs of
                 functional groups; Types of prodrugs.                                          6
                 Chemical delivery systems; Polymeric prodrugs; Types and structure
                 of polymers; Cross-linking reagents.                                           6
   Organic
Pharmaceutical   Drug targeting.
                                                                                                4
 Chemistry IV
                 Project.
                                                                                                4
                 Combinatorial chemistry; Peptides and other linear structures; Drug
                 like molecules; Support and linker; Solution-phase combinatorial               5
                 chemistry.
                Detection, purification and analgesics; Encoding combinatorial
                libraries;
                                                                                         5
                High-throughput screening; Virtual screening; Chemical diversity and
                library design.
                Pharmaceutical dosage forms: Tablets; role in therapy; advantages
                and
                disadvantages; formulation; properties; evaluation; machines used in     10
                tableting; quality control; problems; granulation, and methods of
                production; excipients, and types of tablets.
                Tablet coating; principles; properties; equipments; processing; types
                of                                                                       4
                coating (sugar and film); quality control, and problems.
                Capsules: Hard gelatin capsules; materials; production; filling
                equipments; formulation; special techniques.                             3
                Soft gelatin capsules: Manufacturing methods; nature of capsule shell
                and content; processing and control; stability.                          2
                Micro-encapsulation; core and coating materials; stability;
                equipments                                                               2
                and methodology.
                Modified (sustained release) dosage forms; theory and concepts;
 Industrial     evaluation and testing; formulation.                                     3
Pharmacy II
                Liquids: Formulation; stability and equipments.
                                                                                         3
                Suspensions: Theory; formulation and evaluation.
                                                                                         3
                Emulsions: Theory and application; types; formulation; equipments
                and                                                                      3
                quality control.
                Semisolids: Percutaneouse absorption; formulation; types of bases
                (vehicles) preservation; processing and evaluation.                      3
                Suppositories: Rectal absorption; uses of suppositories; types of
                bases;                                                                   3
                manufacturing processes; problems and evaluation.
                Pharmaceutical aerosols: Propellants; containers; formulation; types
                and
                                                                                         6
                selection of components; stability; manufacturing; quality control and
                testing.
                Interpretation of Lab. data.                                             2
Therapeutic I    Acute coronary syndrome.                                                2
                Arrhythmias                                                              2
                      Thrombosis                                                       2
                      Dyslipidemia                                                     1
                     Stroke                                                            2
                      Shock                                                            2
                      Liver cirrhosis                                                  2
                      Viral hepatitis                                                  1
                      Inflammatory bowel diseases                                      2
                      Acute renal failure (ARF)                                        1
                      Chronic renal failure (CRF)                                      2
                      Hemodialysis and peritoneal dialysis                             1
                      Systemic lupus erythematosis (SLE)                               1
                     Benign prostatic hyperplasia (BPH)                                1
                      Acid – base disorders                                            2
                      Disorders of fluid and electrolytes                              2
                      Urinary incontinence and pediatric enuresis                      1
                      Epilepsy and status epilepticus                                  2
                     multiple sclerosis                                                1
                      Parkinson's disease                                              2
                      Pain management                                                  2
                      Headache disorders                                               1
                     glucoma                                                           2
                      Parenteral nutrition                                             2
                      Enteral nutrition                                                2
                      Pharmacovigilance                                                2
                     Disorders of Carbohydrates metabolism, Hyperglycemia & Diabetes
                     mellitus, Hypoglycemia.                                           3
                     Disorders of lipid metabolism.
                                                                                       2
                     Liver Function Tests.
                                                                                       4
Clinical Chemistry Kidney Function Tests.
                                                                                       4
                     Diagnostic enzymology.
                                                                                       4
                     Hypothalamus & pituitary endocrinology, disorders of anterior
                     pituitary hormones, disorders of adrenal gland, hypopituitrism.   8
                      Reproductive system, disorders of gonadal function in males &
                      females, biochemical assessment during pregnancy.                               5
                      Tumor markers.
                                                                                                      4
                      Drug interaction with laboratory Tests.
                                                                                                      2
                      Disorders of calcium metabolism
                                                                                                      3
                      Acid- Base Disorders.
                                                                                                      4
                      Initial Evaluation and Management of the Poisoned Patient.                      3
                      Including pediatric poisoning and special consideration in the geriatric
                      patient
                      Drug Toxicity: Over the counter drugs; caffeine; theophylline;                  3
                      antihistamine and decongestant; non-steroidal anti-inflammatory
                      drugs; vitamins.
                      Prescription Medications: Cardiovascular drugs; beta blockers; ACE              13
                      inhibitors; Digoxin; Calcium channel blocker; Antiarrhythmic agents;
                      hypoglycemic drugs; Opiods; CNS depressants; tricyclic
                      antidepressants; anti-cholinergic phenothiazines; CNS stimulant.
Clinical Toxicology
                      Drug of Abuse: Opioids; Cocaine; phencyclidine; marijuana; Lysergic acid.       4
                      Chemical and Environmental Toxins: Hydrocarbones; Household                     3
                      toxins; Antiseptic; Disinfectants; Camphor; moth repellents.
                      Botanicals and plants-derived toxins: Herbal preparation; Toxic                 4
                      plants;
                      Poisonous mushrooms.
                      Project.                                                                      (1
     جميع الفروع                                                                                  hours )
                                                                                                     ,
                Course overview & basic principle of pharmacoeconomics                            2
                Cost analysis                                                                     6
                Cost effectiveness analyses (CEA).                                                2
                1st mid-term examination.                                                         2
Pharmacoeconomy
                Cost utility analyses (CUA).                                                      2
                Cost-benefit analysis (CBA)                                                       2
                Critical assessment of economic evaluation                                        4
                2nd mid-term examination.                                                         2
                    Drug-focused versus disease-focused frame work for
                    conducting                                                                2
                    pharmacoeconomic analyses.
                    Introduction to epidemiology.                                             2
                    Project presentation.                                                     2
                    Project presentation.                                                     2
                    Review of basic pharmacokinetic (PK) and pharmacodynamic
                                                                                                  2
                    (PD)
                    Clinical PK equations and calculations                                        3
                    Clinical PK in special population and cases                                   3
                    Clinical PK/PD for Aminoglycosides                                            2
                    Clinical PK/PD for Vancomycin                                                 2
                    Clinical PK/PD for Digoxin                                                    2
 Therapeutic Drug   Clinical PK/PD for Phenytoin                                                  3
   Monitoring       Clinical PK/PD for other Anticonvulsants (e.g., Carbamazepine,
                                                                                                  3
                    Valproic Acid, Phenobarbitone/Primidone, Ethosuxsimide
                    Clinical PK/PD for Theophylline                                               2
                    Clinical PK/PD for Immunossprasants (e.g., Cyclosporine,
                                                                                                  2
                    Tacrolimus
                    Clinical PK/PD for other Cardiovascular agents (e.g., Lidocaine,
                                                                                                  2
                    Procainamide/N-Acetyl Procainamide
                    Clinical PK/PD of other drugs (e.g., Lithium), Anticancer agents,
                                                                                                  4
                                              and Anticoagulats
                    Clinical Pharmacy Practice in Internal Medicine: Clinical observation
                                                       of
                                                                                                  10
                    cases; evaluation of the case sheets; case presentation; discussion and
                                                  evaluation.
                    Clinical Pharmacy Practice in Surgery wards: Clinical observation of
                    cases; evaluation of the case sheets; case presentation; discussion and       5
Hospital Training                                 evaluation.
                      Clinical Pharmacy Practice in Gynecology and Obstetrics Ward:
                       Clinical observation of cases; evaluation of the case sheets; case         5
                                   presentation; discussion and evaluation.
                         Clinical Pharmacy Practice in Pediatric Ward: Neurology ,
                                                                                                  10
                           Cardiology , GIT , Birth defects , Sepesis , Meningitis
                    Thyroid and parathyroid disorders                                             2
                    Contraception                                                                 1
                    Endometriosis                                                                 1
 Therapeutic II
                    Menstruation related disorders                                                1
                    Hormonal replacement therapy (HRT)                                            2
                    Cancer treatment and chemotherapy                                             2
                        Leukemias                                                                  2
                        Lymphomas and Multiple myeloma                                             2
                        Breast and prostate cancers                                                2
                        Adverse effects of chemotherapy                                            1
                        Human immunodeficiency viruse                                              2
                        Adrenal gland disorders                                                    1
                       Pituitary gland disorders                                                   1
                        Alzheimer's disease                                                        1
                        Schizophrenia                                                              2
                        Depressive disorders                                                       2
                        Anxiety disorders                                                          1
                        Sleep disorders                                                            1
                        Bipolar disorders                                                          2
                       colorectal cancer                                                           1
                       Diagnostic test basics, collecting &transporting specimens,             4
                       venipuncture, urine specimen, stool specimen.
                       Biochemical tests: Fasting blood glucose, Post-prandial glucose, Oral   4
                       glucose tolerance test.
                       Blood urea, Blood creatinine, Creatinine clearance, Uric acid.          4
                       Cholesterol, Lipoproteins, triglycerides.                               4
                       Blood proteins, Bilirubin.                                              4
                       Calcium, Inorganic phosphate, Serum chloride                            4
Clinical Laboratory
     Training       Alkaline phosphatase, Acid phosphatase, Alanine amiotransferase,           4
                       Aspartate aminotransferase, Lactate dehydrogenase, Creatine
                       phosphokinase.
                       Serological tests: VDRL, ASO- Titer, Hepatitis tests.                   4
                       C-reactive protein test, Rheumatic factor test, Rosebengal test,        4
                       Typhoid
                       fever test( Widal test), Pregnancy Test.
                       General urine examination, urine specimen collection.                   4
                       Hematological tests: RBC count, Hb, PCV, RBC indices, WBC               4
                       count,
                       Platelets count.
                          Blood typing, Coombs test, Bleeding time, ESR.                              4
                          Microbiological tests: culture and sensitivity tests, Staining methods      4
                          Culture media, Enriched culture media for general use                       4
                          Tests for identification of bacteria, Disk diffusion tests of sensitivity   4
                          to
                          antibiotics, Choice of drugs for disk test, bacterial disease and their
                          laboratory diagnosis.
                          Biotechnology - introduction                                                    1
                          Formulation of biotechnology product (biopharmaceutical                         4
                          consideration) Microbial consideration- sterility-pyrogen viral
                          decontamination Excipients of parentral products - solubility
                          enhancer-anti adsorption agents buffer components-preservatives –
                          osmotic agents
  pharmaceutical
  biotechnology           Route of administration Parentral route       Oral route Alternative            5
                          routes ( nasal-pulmonary-rectal-buccal transdermal )
                          Pharmacokinetic of peptides and proteins Introduction        Elimination        5
                          of proteins (proteolysis-excretion-metabolism )
                          Pharmaceutical consideration: The need for the dosage form.                     1
                           General consideration for the dosage form.                                     3
                           Pre-formulation; physical description, microscopic examination.                2
                           Melting point; phase rule; particle size; polymorphism; solubility.            2
                           Permeability; pH; partition coefficient; pka; stability; kinetics; shelf       2
                          life.
                           Rate reaction; enhancing stability.                                            2
   Dosage form             Formulation consideration: Excipients; definition and types;                   2
     Design               appearance; palatability; flavoring.
                          Sweetening; coloring pharmaceuticals; preservatives; sterilization;             2
                          preservatives selection.
                          Biopharmaceutical considerations: Principle of drug absorption;                 4
                          dissolution of the drugs.
                          Bioavailability and bioequivalancy; FDA requirements.                           3
                          Assessment of bioavailability; bioequivalence among drug products.              3
                          Pharmacokinetic principles: Half life; clearance; dosage regimen                4
                          considerations.
                          UV / visible spectroscopy; Sample handling and instrumentation;             6
Advanced Pharmaceutical   Characteristic absorption of organic compounds; Rules for
       Analyses           calculation of lambda max and application; Application of
                          UV/visible; spectroscopy; Problems and solutions.
Infra Red spectroscopy (theory and H-bonding effect; Sampling       14
techniques and interpretation of spectra; Characteristic group
frequencies of organic compounds; Application of IR spectroscopy;
Problems and solutions.
H1 –Nucleomagnetic Resonance (NMR) and C13-NMR spectroscopy; 12
Introduction, the nature of NMR absorption, chemical shifts and
factors affecting them, information obtained from NMR spectra, more
complex spin-spin splitting patterns, application of H1-NMR
spectroscopy;
C13-NMR spectroscopy: introduction and characteristics, DEPT C13-
NMR spectroscopy.
Mass spectroscopy: Introduction and interpreting Mass spectra;      11
interpreting Mass spectra fragmentation patterns, Mass behavior of
some common functional groups.
elemental microanalysis CHNSO                                       2