Title: Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection
Fraction
Clinical Scenario:
Clinical Question:
Citation:
Directness
Clinical Question Research Question
P Patients with HFpEF
I Dapagliflozin
O Improvement of HF related
symptoms
M
Validity
1. Were patients randomly assigned to treatment Yes
groups?
2. Was allocation concealed?
3.Were baseline characteristics similar at the start? Yes
4. Were patients blinded to treatment assignment? Yes
5. Were caregivers blinded to treatment assignment? Yes
6.Were outcome assessors blinded to No
treatment assignment?
7.Were all patients analysed in the groups to which Yes
they were originally randomized?
8. Was follow-up rate adequate? Yes
Results
Dichotomou Treatmen Control RR RRR ARR NNT
s outcomes t n/N 95% CI 95% CI
n/N
Outcome
Outcome
Continuous Mean Mean Mean 95% C.I. p value
Outcomes (Treatme (control) diff.
nt)
Outcome
Outcome
Applicability Issues
Sex
Comorbidities
Race
Age
Pathology
Socioeconomic issue
Individualizing the results:
Author’s Conclusion
Reviewer’s Conclusion
Clinical Bottom-line
Name: Date: