Pharmacy
Drug Name Route Dosage Form Concentration
Clonidine Oral Suspension 20 mcg/mL
Formula Qty: 300mL Shelf Life: 28 days
Equipment needed:
Mortar and pestle, stirring rod, graduate
Auxiliary labeling/Storage: Shake Well; Refrigerate
Directions:
1. Crush clonidine tablets and triturate to a fine powder in the mortar.
2. Add purified water and mix to form a paste.
3. Slowly add ½ the simple syrup to the mortar and mix well.
4. Transfer to graduated cylinder.
5. Rinse mortar with small amount of simple syrup and add to graduated cylinder. Stir.
6. QS with simple syrup to final volume. Stir well.
Final Product Description: Semi-opaque, orange suspension. No discernible smell.
This description is for exact products and manufacturers specified below and may vary with
substitutions
Ingredient Name/Strength/Form/ Manufacturer QS Quantity Units
Clonidine 0.2mg Tablets Purepac 30 tablet
Purified Water USP 4 mL
Simple Syrup NF X 300 mL
CITATIONS/REFERENCES
1. Pesko LJ. Compounding: Clonidine Oral Liquid. Am Druggist. 1992; (Apr): 68-.
2. Levinson ML, Johnson CE. Stability of an extemporaneously compounded clonidine
hydrochloride oral liquid. Am J Hosp Pharm. 1992; 49(Jan): 122-125
Reviewed: 12/4/2013 CGK
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