1: Surface-active agents are included in some tablets to * 1/1

A Increase the bulk of the tablet

B Make the tablet easier to swallow

C Reduce the disintegration rate of the drug

D Improve the flow properties of the granules

E Increase the dissolution rate of the drug

2: Methyl paraben is:- * 1/1

A methyl ester of Para hydroxy benzoic acid

B diethyl ester

C is an astringent

D used as a disintegrating agent

3:- The system which is composed of a liquid dispersed in a liquid is * 1/1

A a foam

B an emulsion

C a suspension

D an aerosol

E a gel
4: Which of the following characteristics is CORRECT for cationic *1/1
aqueous creams?

A They contain anionic surfactant as part of the primary emulsifying system

B They contain cationic surfactants as part of the primary emulsifying system

C They are incompatible with cations

D The stability of the emulsion is increased when mixed with anionic drugs

E The activity of the drug is increased when mixed with anionic drugs

5: Occlusive dressings are used clinically with topical corticosteroids to * 1/1

A reduce dermal penetration of the steroid

B reduce skin atrophy

C enhance dermal penetration of the steroid

D reduce the incidence of bacterial skin infection

E enhance systemic absorption of steroid

6: All of the following are official pharmacopoeial testing procedures for *1/1
tablets EXCEPT

A dissolution

B hardness

C disintegration

D friability

E content uniformity
7: Methylcellulose and similar agents are MOST commonly used in *1/1
ophthalmic solutions to

A increase drop size

B increase ocular contact time

C reduce inflammation of the eye by their soothing effect

D suspend insoluble drugs

E reduce drop size

8: In which base should hydrocortisone acetate be incorporated to give *1/1

maximal topical absorption?

A Simple Ointment B.P.

B White soft paraffin

C Cetomacrogol cream aqueous

D Wool Alcohols Ointment B.P.

E Hydrous Ointment B.P

9: Sodium metabisulphite is used as * 1/1

A a buffering agent

B an antipruritic

C an antioxidant

D an oxidising agent

E a chelating agent
10: Which ONE of the following suppository bases is immiscible with *1/1
body fluids?

A Gelatin

B Polyethylene glycol

C Glycerinated gelatin

D Cocoa butter

E Macrogol base

11: Which ONE of the following statements about capsules is NOT true? * 1/1

A Liquids can be filled into capsules made from soft or hard gelatine

B Capsules should be stored in areas of low humidity

C In general, increasing the packing density results in a decrease in dissolution rate

D In general, the bioavailability of a powdered drug from a hard gelatine capsule

is less than that of the same drug in a compressed tablet

E Soft gelatine capsules may have an antifungal preservative added to the capsule
shell
12: A suitable method for the sterilisation of a solution of a thermolabile *1/1
drug for ophthalmic use is

A Heating with a bactericide at 100 °C for 30 min

B Aseptic filtration through a membrane filter of 4 micron pore size

C Autoclaving at 121 °C for 15 min

D Aseptic filtration through a membrane filter of 0.2 micron pore size

E Heating at 60 °C for 15 min

13: Which of the following Tablets cannot be crushed * 1/1

A Alendronate and omeprazole

B Apixaban and cyproheptadine

C Enteric coated aspirin

D Both A and C

14: Which of the following emulsifiers is used for parenteral solutions * 1/1

A egg lecithin

B cationic surfactants

C starch

D gelatin

E pectin
15: Cetrimide is a * 1/1

A o/w emulsifying agent

B cationic

C Non-ionic

D anionic

E both A and B

16: Which of the following are Anionic surfactants: * 1/1

A oleic acid

B sodium lauryl sulphate

C Cetrimide

D Tweens and spans

E both A and B

17: Which of the following is not O/W emulsion? * 1/1

A milk

B cold cream

C bees wax

D Both B and C

E vanishing cream
18: What of the following is/are cationic emulsifying agents: * 1/1

A cetyl pyridinium,

B cetrimide,

C benzalkonium chloride

D Docusate sodium

E A, B and C

19: HLB for o/w type of emulsion is * 1/1

A 8 to 20

B 4 to 6

C 2 to 3

D 1.8 to 3

20: What is the use of emulsifier Polysorbate when used with cortisone? * 1/1

A It acts as a solubilizer and wetting agent

B it acts as a disintegrating agent

C acts as a glidant

D acts as a binding agent

E imparts good colour to the emulsion

21: Which property of magnesium stearate enables it to be used as an *1/1
excipient in tablet manufacturing?

A magnesium stearate acts as a dissolution agent

B It helps with the bioavailability of the drug

C It is a surface active agent

D It acts as a lubricant and helps in easy flow of tablets

E It acts as a binding agent

22: Which of the following is not a possibility by which the *1/1

Contamination of drug can occur

A occlusion

B absorption

C inclusion

D exclusion

23: In lab pharmacists should not touch or cut * 1/1

A neoplastic tablet

B sugar syrups

C vit d capsules made of soft gelatin

D hard gelatin capsules containing amoxicillin

E Pharmacists can touch and cut everything

24: Which of the following statements defines molarity? * 1/1

A number of moles in a litre of a solution

B milliosmoles of a substance present in a litre of solution

C negative logarithm of hydrogen ion concentration

D The viscosity of a substance in 1g of a solution

E The gram equivalent of a substance

25: Which of the following statements is/are correct * 1/1

A boric acid is a weak acid

B Eye drops are usually weakly acidic in nature

C Boric acid is used in the formulation of ophthalmic preparations

D Boric acid can act as a buffer in ophthalmic formulations

E All of the above

26: Which of the following statements are true regarding surfactants * 1/1

A They have both hydrophilic and lipophilic entities in the same molecule

B The choice of surfactant is based on its hydrophilic-lipophilic balance.

C These are the compounds which lower the surface tension between two liquids, a
gas and a liquid, or a liquid and a solid.

D They may act as detergents, wetting agents, emulsifiers, foaming agents, or

dispersants.

E All of the above

27: Identify the antioxidant vitamin which can be used in ophthalmic *1/1
preparations from the options given below:

A sodium bisulphite

B sodium metabisulphite

C tocopherol/ vitamin E

D Thiourea

E All of the above

28: Which of the following is not a chelating agent: * 1/1

A magnesium metabisulphite

B Ethylenediamine tetra acetic acid (EDTA)

C Deferoxamine

D Dimercaprol

29: Starch is primarily a: * 1/1

A disintegrant

B suspending agent

C emulsifying agent

D flavoured vehicle

E colouring agent
30: Which of the following are the factors affecting stokes law: * 1/1

A viscosity

B density

C specific gravity

D particle size

E all of the above

31: Which of the following surfactants are compatible with ichthammol * 1/1

A Anionic surfactants

B cationic surfactants

C tweens

D Spans

E magnesium stearate

32: Which of the following statement is /are incorrect for suppositories: * 1/1

A They melt below 30 degrees centigrade

B They are ideal for rectal administration

C an Ideal suppository base is inert and compatible with active ingredient

D An ideal suppository base should be non-irritating

E An ideal suppository base has emulsifying and wetting properties

33: Dry powder is sterilized for: * 1/1

A At 160 degrees for 120min

B At 160 degrees for 60 min

C At 160 degrees for 75 min

D At 110 degree for 40min

E At 100 degrees for 45 minutes

34: Which of the following is used as a coating agent for sustained *1/1
release morphine:

A Hypromellose (hydroxy propyl methyl cellulose

B Starch

C Animal gelatin

D pectin

E cellulose acetate phthalate

35: Calcium oleate is an: * 1/1

A emulsifying agent

B binding agent

C coating agent

D glidant

E colouring agent
36: Chlorocresol is used as a preservative in oil-in-water creams at a *1/1
percentage concentration of

A 0.001

B 0.01

C 0.1

D 0.5

E 1.0

37: Stearyl alcohol, cetyl alcohol, cholesterol and other related *1/1
compounds are used as

A Solvents for steroidal drug prescriptions

B Preservatives in small volume parenteral preparations

C Primary emulsifiers for oil in water preparations

D Stabilisers in emulsion formulations

E Surfactants for topical preparations

38: Which is not miscible or soluble with alcohol * 1/1

A acacia

B ether

C water

D chloroform
39: The emulsifying agent in olive /lime water emulsion is * 1/1

A calcium oleate

B Ammonium laurate

C docusate sodium

D triethanolamine palmate

E ammonium stearate

40: Mineral oil not soluble in- * 1/1

A water

B ethanol (alcohol)

C Both A and B

D benzene

E ether

41: Degradation of pharmaceutical products occurs mostly due to * 1/1

A hydrolysis

B oxidation

C Photolysis

D reduction
42: Release of ingredients from original product is called * 1/1

A leaching

B diffusion

C adsorption

D porosity

43: Which of the following statement/ statements are true regarding *1/1
spans:

A span can be used as a wetting agent

B span can be used as an antifoaming agent

C spans are hydrophobic with low HLB value

D They are sorbitan esters used to prepare w/o type of emulsions

E all of the above

44: Which of the following statement/s regarding tweens are true: * 1/1

A They are chemically Polysorbates with high HLB value

B They are used as an emulsifying agent in o/w type of emulsions

C They are used as solubilizing agents and detergents

D They are hydrophilic in nature

E All of the above

45: Methyl cellulose is to be added to suspension formula to * 1/1

A improve the flavour of the suspension

B promote caking of the suspension

C decrease sedimentation rate

D As a preservative

E It improves the astringent properties of the suspension.

46: Best method to make a suppository containing cocoa butter is * 1/1

A base-compression method (cold compression method)

B Fusion method

C melt method

D levigation method

E Rolling method

47: Which of the following can be used as an enteric coating agent * 1/1

A Cellulose acetate phthalate

B Bees wax

C citric acid

D Tartaric acid

E Tannic acid
48: Tablet mottling refers to * 1/1

A Separation of tablet into multiple layers

B unequal colour distribution

C breaking of the tablet on application of pressure

D sticking of the tablet to walls of die

E Separation of the upper crown layer of the tablet

49: According to stokes law sedimentation rate is * 1/1

A indirectly proportional to viscosity

B indirectly proportional to the particle size

C indirectly proportional to the density

D indirectly proportional to the acceleration due to gravity

50: The combination of Polysorbate and coal tar is used in formulations *1/1
as they promote the following nature to the formulation

A dispersing

B solubilizing

C disintegration

D Both A and B
51: Hypromellose is used as * 1/1

A primarily a coating agent

B Secondarily a binding agent

C used to coat sustained release formulation of morphine

D increases formulation efficiency, resistance to chipping, and output

E All the above statements regarding Hypromellose are correct.

52: Talc added in concentrated aromatic water serves as a * 1/1

A Dispersant

B Binding agent

C Disintegrating agent

D Flavouring agent

E preservative

53: Which one of the following is hypotonic to 0.9% Nacl * 1/1

A 0.45% normal saline,

B 30% dextrose

C 30% sucrose

D Both are isotonic to each other

54: Which of the following types of Emulsion is a good conductor of *1/1
electricity

A O/W

B W/O

C both equally conduct electricity

D depends on the emulsifying agent used

E depends on the viscosity of the emulsion

55: Which of the following acids are not used to extract materials * 1/1

A Hydrochloric acid

B alginic acid

C sulphuric acid,

D Nitric acid

56: A prescription calls for 0.1% chlorhexidine hydrochloride in an oil-in- *1/1

water emulsion cream base. Which ONE of the following is the MOST
suitable emulgent for the preparation of the base?

A Sodium lauryl sulphate

B Wool alcohols

C Cetrimide

D Sodium stearate

E Calcium oleate
57: What needle size has the smallest diameter? * 1/1

A 28 gauge

B 25 gauge

C 22 gauge

D 19 gauge

E 18 gauge

58: what %w/w imparts self preservative nature for sugar * 1/1

A 65%

B 50%

C 22%

D 10%

E 5%

59: Which of the following statement/s of Salicyclic acid in sulphur *1/1

ointment are true:

A It is hydrophilic, water miscible,

B It is non occlusive, water washable

C It is primarily used to treat fungal infections

D It is an example of o/w emulsion

E All the above statements are true

60: Boric acid: * 1/1

A has weak antiseptic properties

B can be used in preparation of mouth wash

C acts as a buffering agent in ophthalmic

D is weakly acidic in nature

E All of the above statements regarding boric acid are true.

61: Which of the following is not important for Cockcroft –Gault *1/1
equation

A serum urea

B age

C body weight of the patient

D serum creatinine

E gender
62: Regarding the rectal dosage forms identify the incorrect statement/s *1/1
from the options given below:

A suppositories are an example of rectal dosage forms

B suppositories are usually cylindrical and tapered to a point, forming a bullet-like

shape.

C Base solubility and melting point is not an important factor for rectal dosage
form preparation

D The base should be inert and compatible with a variety of drugs

E The base should be nonirritating and non-sensitizing and have wetting and
emulsifying properties

63: The reason for enteric coating of kcl is * 1/1

A to improve texture

B to improve the viscosity and solubility of the compound

C to reduce gastric irritation caused by Kcl

D to improve its flowing properties during drug manufacturing

E Enteric coating agents prevent microbial contamination of kcl

64: Ethylene oxide is the only gas sterilant used because * 1/1

A because its not explosive

B it is sporicidal

C it is non toxic

D it is non carcinogenic
65: Eye ointment -should always * 1/1

A Be sterile

B Always have a preservative

C be soluble in water

D Have active ingredient soluble in the base

66: An ointment has bismuth subgallate with hydrocortisone bismuth *1/1

gallate is used as

A Astringent

B Emollient

C preservative

D anti-oxidant

E emulsifying agent

67: If you must add 25 ml of water to 75 g of wool fat to make lanolin, *1/1
how many milliliters of water should be added to 1 lb. of wool fat to
make lanolin?

A 150ml

B 180ml

C 120ml

D 180ml