1.
Ashwagandha Extract (KSM-66)
Potency: High
Effectiveness: Strong evidence supports Ashwagandha for boosting testosterone,
reducing stress, and improving sperm quality.
Mechanism: Adaptogenic herb that lowers cortisol and enhances testosterone
production.
Evidence-Based Benefits:
o Increases Testosterone Levels: Studies show up to a 17% increase in
testosterone and improved sexual health.
o Improves Sperm Count and Motility: Significant increases in sperm count and
motility in men with infertility.
o Reduces Stress and Anxiety: Improves overall reproductive function by
balancing hormones.
Suggested Dosage: 600 mg daily of KSM-66 standardized extract (5% withanolides).
2. Tongkat Ali (Eurycoma longifolia)
Potency: High
Effectiveness: Effective in increasing testosterone, enhancing libido, and reducing stress.
Mechanism: Promotes testosterone production and reduces cortisol.
Evidence-Based Benefits:
o Boosts Testosterone: Clinical studies report increased testosterone and sexual
desire.
o Improves Erectile Function and Libido: Effective in enhancing sexual
performance and reducing fatigue.
o Reduces Stress: Improves mood and hormone balance.
Suggested Dosage: 200–400 mg daily of standardized extract (1–2% eurycomanone).
3. Shilajit (Purified, Fulvic Acid)
Potency: High
Effectiveness: Highly effective for enhancing testosterone and improving sperm health.
Mechanism: Rich in minerals and fulvic acid, supporting energy production and
testosterone.
Evidence-Based Benefits:
o Increases Testosterone and Sperm Quality: Studies show significant increases
in testosterone, sperm count, and motility.
o Boosts Mitochondrial Function: Improves energy and stamina, vital for sexual
health.
Suggested Dosage: 300–500 mg daily, standardized to 60% fulvic acid.
4. Coenzyme Q10 (Ubiquinol)
Potency: High
Effectiveness: Potent antioxidant that enhances sperm motility and energy production.
Mechanism: Supports mitochondrial function and reduces oxidative damage in sperm.
Evidence-Based Benefits:
o Improves Sperm Motility and Morphology: Ubiquinol is particularly effective
for men with idiopathic infertility.
o Protects Against Oxidative Stress: Improves sperm quality by reducing DNA
fragmentation.
Suggested Dosage: 100–300 mg daily of Ubiquinol (the active form of CoQ10).
5. N-Acetylcysteine (NAC)
Potency: High
Effectiveness: Effective for reducing oxidative stress and improving hormonal balance.
Mechanism: Increases glutathione levels, protecting sperm from oxidative damage.
Evidence-Based Benefits:
o Enhances Sperm Quality: Significant improvements in sperm motility,
morphology, and count in men with oxidative stress.
o Supports Testosterone Production: Shown to help regulate testosterone levels.
Suggested Dosage: 600–1,200 mg daily.
6. Astaxanthin
Potency: High
Effectiveness: Strong antioxidant properties that protect sperm and enhance sexual
health.
Mechanism: Reduces oxidative damage and boosts mitochondrial energy.
Evidence-Based Benefits:
o Improves Sperm Quality: Shown to increase motility and reduce DNA
fragmentation.
o Boosts Hormonal Health: Supports testosterone production and overall
reproductive function.
Suggested Dosage: 4–8 mg daily.
7. Fenugreek Extract (Testofen)
Potency: Medium-High
Effectiveness: Well-studied for boosting testosterone and libido.
Mechanism: Contains saponins that stimulate testosterone production.
Evidence-Based Benefits:
o Increases Testosterone Levels and Libido: Clinical trials demonstrate
significant improvements in sexual arousal and satisfaction.
o Enhances Strength and Stamina: Effective for overall physical and sexual
performance.
Suggested Dosage: 500–600 mg daily of standardized extract (50% fenusides).
8. Mucuna Pruriens (Velvet Bean)
Potency: Medium-High
Effectiveness: Supports hormonal balance and reduces stress.
Mechanism: Contains L-Dopa, which increases dopamine and boosts testosterone.
Evidence-Based Benefits:
o Improves Sperm Quality: Effective in stress-related infertility, enhancing sperm
count and motility.
o Increases Testosterone and Reduces Oxidative Stress: Positive effects on
reproductive health.
Suggested Dosage: 500–1,000 mg daily of standardized extract (15–20% L-Dopa).
9. Maca Root (Gelatinized Maca Extract)
Potency: Medium-High
Effectiveness: Known to boost libido and support hormone balance.
Mechanism: Works as an adaptogen to regulate hormones.
Evidence-Based Benefits:
o Enhances Libido and Sexual Performance: Significant improvements in sexual
desire and satisfaction.
o Improves Sperm Count and Motility: Effective as a supportive fertility
enhancer.
Suggested Dosage: 1,500–3,000 mg daily of gelatinized extract.
10. L-Carnitine (Acetyl-L-Carnitine)
Potency: Medium
Effectiveness: Supports sperm motility and reduces oxidative stress.
Mechanism: Enhances mitochondrial energy production in sperm cells.
Evidence-Based Benefits:
o Improves Sperm Motility: Beneficial for men with low sperm motility.
o Protects Sperm from Oxidative Damage: Increases sperm viability.
Suggested Dosage: 1,000–2,000 mg daily.
11. Omega-3 Fatty Acids (DHA)
Potency: Medium
Effectiveness: Supports sperm membrane health and reduces inflammation.
Mechanism: Improves cell membrane fluidity and overall sperm quality.
Evidence-Based Benefits:
o Enhances Sperm Count and Motility: Associated with better reproductive
outcomes.
o Reduces Inflammation: Supports cardiovascular and hormonal health.
Suggested Dosage: 1,000–2,000 mg daily of combined EPA/DHA.
12. L-Arginine
Potency: Medium
Effectiveness: Effective for erectile dysfunction and improving blood flow.
Mechanism: Increases nitric oxide production, enhancing blood circulation.
Evidence-Based Benefits:
o Improves Erectile Function: Used to treat mild to moderate erectile dysfunction.
o Supports Sexual Stamina: Enhances overall blood flow and performance.
Suggested Dosage: 2,000–3,000 mg daily.
13. Boron
Potency: Medium
Effectiveness: Effective in increasing free testosterone and reducing inflammation.
Mechanism: Lowers SHBG and increases bioavailable testosterone.
Evidence-Based Benefits:
o Boosts Testosterone Levels: Shown to increase free testosterone in men.
o Supports Bone and Joint Health: Indirectly benefits reproductive health.
Suggested Dosage: 3–6 mg daily.
14. Ginkgo Biloba
Potency: Medium
Effectiveness: Known to enhance blood flow and reduce anxiety.
Mechanism: Improves microcirculation and acts as an antioxidant.
Evidence-Based Benefits:
o Improves Erectile Function: Beneficial for men with circulation issues.
o Reduces Stress and Anxiety: Enhances mental well-being, indirectly benefiting
sexual performance.
Suggested Dosage: 120–240 mg daily of standardized extract (24% flavone glycosides).
15. Lycopene
Potency: Medium
Effectiveness: Protects sperm from oxidative damage and supports prostate health.
Mechanism: Antioxidant properties that improve sperm morphology.
Evidence-Based Benefits:
o Enhances Sperm Quality: Shown to improve sperm morphology and DNA
integrity.
o Supports Prostate Health: Protects against prostate-related issues.
Suggested Dosage: 10–15 mg daily.
16. Beetroot
Potency: Medium
Effectiveness: Increases nitric oxide levels, improving blood flow and stamina.
Mechanism: High nitrate content that enhances vascular function.
Evidence-Based Benefits:
o Improves Blood Flow: Beneficial for erectile function and physical endurance.
o Supports Stamina and Energy: Boosts oxygen delivery during physical
activities.
Suggested Dosage: 500–1,000 mg daily.
17. Selenium (Selenomethionine)
Potency: Medium-Low
Effectiveness: Important for sperm motility and DNA protection.
Mechanism: Antioxidant that works synergistically with Vitamin E.
Evidence-Based Benefits:
o Enhances Sperm Motility: Essential trace mineral for reproductive health.
o Protects Sperm from Oxidative Damage: Reduces DNA fragmentation.
**Suggested Dosage
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:** 55–100 mcg daily.
18. Vitamin B6 (Pyridoxal-5-Phosphate, P-5-P)
Potency: Medium-Low
Effectiveness: Supports hormonal balance and neurotransmitter synthesis.
Mechanism: Active form that regulates testosterone and reduces stress.
Evidence-Based Benefits:
o Improves Mood and Reduces Anxiety: Important for mental and sexual well-
being.
o Supports Testosterone Levels: Regulates hormone balance.
Suggested Dosage: 10–50 mg daily.
19. Vitamin E (α-Tocopherol)
Potency: Medium-Low
Effectiveness: Protects sperm from oxidative damage.
Mechanism: Antioxidant that enhances sperm quality when combined with selenium.
Evidence-Based Benefits:
o Improves Sperm Motility and Morphology: Effective in combination with
antioxidants.
Suggested Dosage: 100–400 IU daily.
20. Vitamin B12 (Methylcobalamin) & Folic Acid
Potency: Medium-Low
Effectiveness: Essential for DNA synthesis and sperm quality.
Mechanism: Supports cellular division and reduces sperm abnormalities.
Evidence-Based Benefits:
o Enhances Sperm Quality: Reduces DNA damage and improves concentration.
o Supports Energy and Reduces Fatigue: Beneficial for overall reproductive
health.
Suggested Dosage: B12: 1,000–2,000 mcg; Folic Acid
