كلية العلوم الصحية
والتمريض
Experiment No 2 Date…………………………..
Quantitative Estimation of Antiacid in Solution (Moles/liter)
Aim :
To estimate the concentration of sodium bicarbonate present in the given anti-acid solution, in moles/liter
Principle:
Sodium bicarbonate is an antiacid used to relieve heartburn and acid indigestion, the method is an acid- base
titration method, since sodium bicarbonate is weak base, it is neutralized with hydrochloric acid.
HCl + NaHCO3 → NaCl + H2O + CO2
Hydrochloric acid Sodium Bicarbonate Sodium Chloride Carbon dioxide
Each 1 mole of hydrochloric acid ≡ 1 mole of Sodium Bicarbonate
Materials required
Sample, hydrochloric acid, methyl orange indicator, Burette, Pipette, Conical flask, dropper , beaker and measuring
cylinder.
.
Assay Procedure
1. Fill the burette with HCl up to Zero
2. Pipette 20 mL of the sample and transfer into a conical flak.
3. Add 2 drops of methyl orange indicator (yellow color will appear)
4. Titrate with 0.1 M hydrochloric acid solution until you obtain the end point. Yellow color change to pink).
5. Repeat the procedure for three times and record the readings
Result
Burette Reading Volume of Average
S. NO. 0.05M HCl Volume of
Initial Final solution used 0.05M HCl
Average
Volume of HCl ……………………….
𝑀𝑜𝑙𝑎𝑟𝑖𝑡𝑦 𝑜𝑓 𝐻𝐶𝑙 𝑠𝑜𝑙𝑢𝑡𝑖𝑜𝑛 × 𝑣𝑜𝑙𝑢𝑚𝑒 𝑜𝑓 𝐻𝐶𝑙 𝑠𝑜𝑙𝑢𝑡𝑖𝑜𝑛 𝑐𝑜𝑛𝑠𝑢𝑚𝑒𝑑
𝑁𝑜. 𝑜𝑓 𝑚𝑜𝑙𝑒𝑠 𝑜𝑓 𝐻𝐶𝑙 𝑐𝑜𝑛𝑠𝑢𝑚𝑒𝑑 =
1000
No. of Moles of HCl = -------------- Moles.
No. of Moles of HCl = No. of Moles of sodium bicarbonate (Na HCO3)
= --------------Moles
- No. of Moles of sodium bicarbonate (20 ml) = -------------- Moles.
𝑵𝒐. 𝒐𝒇 𝒎𝒐𝒍𝒆𝒔 𝒐𝒇 𝒔𝒐𝒅𝒊𝒖𝒎 𝒃𝒊𝒄𝒂𝒓𝒃𝒐𝒏𝒂𝒕𝒆 × 𝟏𝟎𝟎𝟎
𝑵𝒐. 𝒐𝒇 𝒎𝒐𝒍𝒆𝒔 𝒐𝒇 𝐬𝐨𝐝𝐢𝐮𝐦 𝐛𝐢𝐜𝐚𝐫𝐛𝐨𝐧𝐚𝐭𝐞𝒊𝒏 𝟏 𝑳 =
𝑽𝒐𝒍𝒖𝒎𝒆 𝒐𝒇 𝒔𝒂𝒎𝒑𝒍𝒆 (𝒎𝑳)
= -------------------- Mole/l
Conclusion
The no of moles of sodium bicarbonate in anti-acid sample was found to be …………………. Mole\l
Questions
Calculate the weight of carbonate ………………………………………..
