BIOMOLECUELS Hasin Ahmed Dekho seekho jano 9425761832
Case Study based Question No --1
Read the passage given below and answer the following questions:
When a protein in its native form, is subjected to physical changeslike change in temperature or
chemical changes like change in pH, the hydrogen bonds are disturbed. Due to this, globules unfold and
helix gets uncoiled and protein loses its biological activity. This is called denaturation of protein.
The denaturation causes change in its secondary and tertiary structures but primary structures remains
intact. Examples of denaturation of protein are coagulation of egg white on boiling, curding of milk,
and formation of cheese when an acid is added to milk.
The following 1 to 5 questions are multiple choice questions. Choose the most appropriate answer
Q1. Find the wrong statement about denaturation of proteins.
(a) The primary structure of the protein does not change.
(b) Globular proteins are converted into fibrous proteins.
(c) Fibrous proteins are converted into globular proteins. c
(d) The biological activity of the protein is destroyed.
Q2. Which statement(s) of protein remain(s) intact during denaturation process?
(a) Both secondary and tertiary structures
(b) primary structure only
(c) secondary structure only
(d) tertiary structure only Answer: (b) primary structure only
Q3. α-helix and β-pleated structures of proteins are classified as,
(a) primary structure of protein (b) secondary structure of protein
(c) tertiary structure of protein (d) quaternary structure of protein
Answer: (b) secondary structure of protein
Q4. Cheese is a
(a) globular protein (b) conjugated protein (c) denatured protein (d) derived protein
Answer:(c) denatured protein
Q5. Secondary structure of protein refers to,
(a) mainly denatured of proteins and structures of prosthetic groups
(b) three-dimensional structure, especially the bond between amino acid residues that are distant from
each other in the polypeptide chain
(c) linear sequence of amino acid residues in the polypeptide chain
(d) regular folding patterns of continuous portions of the polypeptide chain.
Answer: (d) regular folding patterns of continuous portions of the polypeptide chain
BIOMOLECUELS (2)
Match the following:
Column I column II
(i)Amino acids (A) Protein
(ii)Thymine (B) Nucleic acid
(iii) Uracil (C)DNA
(iv)Phosphodiester linkage (D) RNA
(v)Insulin
Which of the following are the best matched options?
(a) i-A, v- D, iii- C, iv-B
(b) i-D, ii-C, iii- A, iv-B
(c) i-D, v- D, iii- A, iv-B
(d) i-A, ii- C, iii- D, iv-B D
Match the following:
I II
(i) D,L Configuration (A) C-1 carbon
(ii) Anomers (B) Glyceraldehyde
(iii) Lactose (C)Glucose
(iv) Aldohexose (D) Milk
(v) Furanose
Which of the following are the best matched options?
(a) i-B, ii-A- iii-D, iv- C
(b) i-C, ii-D, iii- A, iv-B
(c) i-B, ii-C, iii- D, iv-A
(d) i-A, ii- C, iii- D, iv-B a
8. A diabetic person carries a packet of glucose with him always, because
(a) glucose increases the blood sugar level slowly
(b) glucose reduces the blood sugar level
(c) glucose increases the blood sugar level almost instantaneously
(d) glucose reduces the blood sugar level slowly
Answer: (c) glucose increases the blood sugar level almost instantaneously
9. Amino acids generally exist in the form of Zwitter ions, which means they contain,
(a) Basic – NH2 group and acidic – COOH group
(b) The basic – NH3+ group and acidic – COO– group
(c) Basic -NH2 and acidic – H+ group
(d) Basic – COO– group and acidic – NH3+ group
Answer: (d) Basic – COO– group and acidic – NH3+ group
10. Globular proteins are present in
(a) blood (b) egg (c) milk (d) all of the above
11. Which one of the amino acids can be synthesized in the body?
(a) Alanine (b) Lysine (c) Valine (d) Histidine a
12. Which of the following is not true about amino acids?
(a) Amino acids are constituents of all proteins
(b) Alanine is having one amino and one carboxylic group
(c) Most naturally occurring amino acids have D-configuration
(d) Glycine is the only naturally occurring amino acid which is optically inactive. C
13. A compound which contains both …………….……… and ……………….… is called amino acid. The
amino acids are joined by ……………………..… bonds to make polypeptide chain,
(a) amino, carboxylic group, ester (b) amino, carboxylic group, peptide
(c) nitrogen, carbon, glycosidic (d) hydroxy, carboxylic group, peptide
14. Denaturation of protein leads to loss of its biological activity by,
(a) formation of amino acids (b) disruption of primary structure
(c) disruption of both primary and secondary structure
(d) disruption of both secondary and tertiary structures only
15. Proteins are condensation polymers of,
(a) α-amino acids (b) β-amino acids (c) α-hydroxy acids (d) β-hydroxy acids
